Signs of a still active, ongoing borrelia infection?

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Signs of a still active, ongoing borrelia infection?

Post by X-member » Sun 9 Feb 2014 18:11

Video-microscopy and pictures of Borrelia burgdorferi and other spirochete like structures links collection
Dr Marie Kroun, Denmark

http://lymerick.net/videomicroscopy.htm

A quote:
It is important to understand that Borrelia burgdorferi can only be hit by antibiotics, when they are active and proliferating! – i.e. during the patients SYMPTOMATIC PERIODS! – which can be judged ONLY by patients detailed symptom log, especially if it shows the for Borrelia typical cyclical pattern repeatedly! – combined with multiple tests able to diagnose ACTIVE Borrelia infection specifically, and other test done to out rule other possible causes of the patients symptoms!

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Re: Signs of a still active, ongoing borrelia infection?

Post by X-member » Thu 27 Feb 2014 18:34

One more quote from the link in the post above:
A positive response to trial antibiotic treatment should always be taken as a sign that the patient has an ongoing infection that is treatable by antibiotics, whether is has been proven to be due to ACTIVE Borreliosis or not! The SYMPTOMATIC patient should NOT be denied further antibiotic treatment, because symptoms can be abrogated, just like when treating herpes with acyclovir, and because perhaps long lasting debilitating symptoms can possibly be prevented by prompt treatment every time the patients Borreliosis flares up?!

If a patient improves (again and again) on given antibiotic treatment, despite the doctor can perhaps not put a name to the infection yet (because the right test weren’t done at the right time)! – the patients physician should see the antibiotic-responsiveness as sign that this patient needs further testing AND offer treatment until the patient is no longer symptomatic!

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Re: Signs of a still active, ongoing borrelia infection?

Post by X-member » Mon 3 Mar 2014 21:48

More (from the link in the first post):
THESE AND MANY OTHER PUBLISHED WORKS ALL EMPHASISE THAT ANY NEGATIVE BORRELIA SEROLOGY TEST CAN NOT BE USED TO EXCLUDE PERSISTENT ACTIVE BORRELIOSIS in the SYMPTOMATIC PATIENT – not even when more SEROLOGY tests are being used in combination!

Thus a declne in antibody result after antibiotic treatment, SHOULD NOT be taken as a positive sign of the Borrelia infection was cured forever, especially not when the patients symptoms recur shortly!
when symptoms reappear within less than 1-3 YEARS after stopping antibiotic treatment for proven Borrelia infection, then suspect a relapse of ACTIVE Borreliosis and seek proof of it by all possible means!

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Re: Signs of a still active, ongoing borrelia infection?

Post by X-member » Mon 3 Mar 2014 21:57

And, I don't think that a relapse mean that the patient only get a new erythema migrans rash. :roll:


Reinfection in Patients with Lyme Disease

http://cid.oxfordjournals.org/content/45/8/1032.full

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Re: Signs of a still active, ongoing borrelia infection?

Post by X-member » Tue 4 Mar 2014 0:03

Borrelia burgdorferi detected by culture and PCR in clinical relapse of disseminated Lyme borreliosis.
Oksi J1, Marjamäki M, Nikoskelainen J, Viljanen MK.


http://www.ncbi.nlm.nih.gov/pubmed/10442678

A quote:
We conclude that the treatment of Lyme borreliosis with appropriate antibiotics for even more than 3 months may not always eradicate the spirochete. By using PCR, it is possible to avoid unnecessary retreatment of patients with 'post-Lyme syndrome' and those with 'serological scars' remaining detectable for months or years after infection.
Last edited by X-member on Fri 27 Mar 2015 3:47, edited 1 time in total.

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Re: Signs of a still active, ongoing borrelia infection?

Post by X-member » Tue 4 Mar 2014 12:16

Microscopy, Culture or PCR-verified cases of persistent [seronegative] Lyme Borreliosis (Marie Kroun)

http://lymerick.net/persistent-borreliosis.html

A quote:
ABSCENCE OF PROOF FOR INFECTION, IS NOT PROOF FOR ABSCENCE OF INFECTION!
A diagnosis of chronic borreliosis can not be made from positive, nor can it be excluded from negative test results solely!
Borreliosis is mainly a CLINICAL DIAGNOSIS, that must be based on a disease history with:
1. suspected/known EXPOSURE to tick/Borrelia/other TBI (previously recognized tickbite, previous erythema migrans, previous or current positive serology are all positive indicators of exposure to Borrelia plus eventual other tickborne infections simultaneously)
2. CURRENT SYMPTOMATOLOGY especially when in a characteristic cyclical pattern (prospectively registered / described in a very detailed symptom log (Excel diary) and might be
3. supported by positive test results, and last but not least, the
4. RESPONSE TO ANTIBIOTIC TREATMENT (followed from day to day with the diary, during treatment, compared to before treatment, will measure and document both beneficial as well as adverse effect of antibiotic treatment!)
- are all factors that must be taken into consideration by the patient and doctor, when establishing diagnosis and decide on treatment!

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Re: Signs of a still active, ongoing borrelia infection?

Post by X-member » Fri 27 Mar 2015 3:31

I activate this thread since a person ask a question about this in another thread.

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Re: Signs of a still active, ongoing borrelia infection?

Post by X-member » Tue 31 Mar 2015 16:45

Perhaps this belong in this thread too?

Studies or research on late complicated Lyme

http://www.lymeneteurope.org/forum/view ... 536#p25874

A quote:
CONCLUSIONS: Our data implicate B henselae as a potential human tick-borne pathogen. Patients with a history of neuroborreliosis who have incomplete resolution of symptoms should be evaluated for B henselae infection*.
* And/or other infections.

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Re: Signs of a still active, ongoing borrelia infection?

Post by X-member » Mon 4 Apr 2016 20:21

ADVANCED TOPICS IN LYME DISEASE DIAGNOSTIC HINTS AND TREATMENT GUIDELINES FOR LYME AND OTHER TICK BORNE ILLNESSES (Dr Burrascano)

http://www.borrelia-tbe.se/media/burrguide200810.pdf

A quote:
It has been observed that symptoms will flare in cycles every four weeks. It is thought that this reflects the organism’s cell cycle, with the growth phase occurring once per month (intermittent growth is common in Borrelia species). As antibiotics will only kill bacteria during their growth phase, therapy is designed to bracket at least one whole generation cycle. This is why the minimum treatment duration should be at least four weeks. If the antibiotics are working, over time these flares will lessen in severity and duration. The very occurrence of ongoing monthly cycles indicates that living organisms are still present and that antibiotics should be continued.

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Re: Signs of a still active, ongoing borrelia infection?

Post by X-member » Sat 23 Jul 2016 15:24

Bump!

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