http://www.newhaven.edu/515835/http://www.embl.de/aboutus/communicatio ... index.html
Henrietta Lacks had Syphilis and they knew spirochetal prion proteins could not be killed as testified before Congress.
Coexistence of ribbon and helical fibrils originating from hIAPP20–29 revealed by quantitative nanomechanical atomic force microscopy
Uncontrolled misfolding of proteins leading to the formation of amyloid deposits
is associated with more than 40 types of diseases,
such as neurodegenerative diseases and type-2 diabetes.
These irreversible amyloid fibrils typically assemble in distinct stages. Transitions among the various intermediate stages are the subject of many studies
but are not yet fully elucidated.
Here, we combine high-resolution atomic force microscopy and quantitative nanomechanical mapping to determine the self-assembled structures of the decapeptide hIAPP20–29, which is considered to be the fibrillating core fragment of the human islet amyloid polypeptide (hIAPP) involved in type-2 diabetes.
We successfully follow the evolution of hIAPP20–29 nanostructures over time, calculate the average thickening speed of small ribbon-like structures, and provide evidence of the coexistence of ribbon and helical fibrils, highlighting a key step within the self-assembly model.
In addition, the mutations of individual side chains of wide-type hIAPP20–29 shift this balance and destabilize the helical fibrils sufficiently relative to the twisted ribbons to lead to their complete elimination. We combine atomic force microscopy structures, mechanical properties, and solid-state NMR structural information to build a molecular model containing β sheets in cross-β motifs as the basis of self-assembled amyloids.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581879/
40 diff. diseases...LOL
TRY HUNDREDS OF LIES OF SINdromes. http://online.wsj.com/article/PR-CO-201 ... 04463.html
July 12, 2013, 6:05 a.m. ET
Autism Epidemic Linked to Epidemic of Vaccine Induced Diabeteshttp://www.biomedcentral.com/1471-2180/9/137
Genome sequencing of diverse bacterial species has revealed widespread distribution of conserved gene products
with as-yet unknown functions.
Among these are a family of small proteins with approximate molecular masses of 12 kDa, which have been variously classed as
"domain of unknown function" (DUF) 149, Pfam 2575 and COG-0718 .
Such genes have been identified in a wide variety of bacterial phyla,
a list that includes many significant pathogens of humans, domestic animals and plants (Fig. 1).
thumbnailFigure 1. Alignment of the predicted amino acid sequences of YbaB/EbfC orthologs of
H. influenzae (Hi),
E. coli (Ec),
Vibrio cholerae (Vc),
Pseudomonas putida (Pp),
Rickettsia rickettsiae (Rr),
Neisseria gonorrhoeae (Ng),
Bdellovibrio bacteriovorus (Bba),
Clostridium perfringens (Cp),
Bacillus subtilis (Bs),
Enterococcus faecalis (Ef),
Streptococcus pneumoniae (Sp),
Mycobacterium tuberculosis (Mt),
Bacteroides capillosus (Bc), and
B. burgdorferi (Bbu).
Identical amino acids are boxed and shaded. Amino acid residues of YbaBEc and YbaBHi that comprise αlpha-helices 1 and 3 of their determined protein structures are identified.
DNA-binding by Haemophilus influenzae and Escherichia c
You see they HAD to have have known. They KNEW in 1985 what really caused AIDS immune suppression.
Gene sharing stealth they gave us.
Just like they knew when they gave our soldiers Anthrax and Smallpox vaccines so they could get its and giggles watching them suffer lies of PTSD by the THOUSANDS as 22 a day take their own lives from brain altering infections.