LymeNet Europe

Bumping old topic, looking for new information.

I find this part really intriguing: In patients with late Lyme disease, antibodies to OspA are present [27]. In a prospective study performed in-house on over 400 PCR positive patients with late-stage Lyme disease, 71% had a positive WB (interestingly, 43% of these patients only had a positive IgM ...

Also, if there are still "signs" in the blood, what are are they? Then what happens as far as diagnosis and treatment when it's not "a clean bill of health?"

from article "Tick test for persistent Lyme disease tried in humans" By Kathryn Doyle NEW YORK Fri Feb 28, 2014 11:29am EST For most people who contract Lyme disease, a couple of weeks of antibiotics clear up the infection easily. About four weeks later, patients with no signs of the infecting bact...

Agree. Thanks for summarizing -- and explaining -- the big picture so well. The quote from Levin was to point out how problematic the CDC 10 band selected criteria is, clearly illustrated by running a computer program to analyze band patterns just on his samples (maybe even supplied to Levin from th...

Adding this post by Dr. MacDonald from thread "NIH Videocast: Ticks - Lyme & Other Diseases" http://www.lymeneteurope.org/forum/viewtopic.php?f=7&t=5237 because of its relevance to the discussion on IgM antibodies here. Dr. Tom Schwan PHD of Rocky Mtn Lab, Hamilton , Montana informs us that For RELA...

Pamela Weintraub, in Cure Unknown , pgs 118-119, wrote: Even Andrew Levin, founder and president of Immunetics, the Cambridge, Massachusetts, company that manufactures the Western blots used by commercial labs, has his doubts. Suspecting the CDC pattern was overly ridged and prone to miss cases, he...

Thanks ChuckG, for posting a link to the full paper. Very interesting for me to note all the sources of the various citations included in the article, and also that John F Anderson is one of this article's co-authors. Dr. Anderson is one of the original team members of the group from Connecticut/Yal...

Hi duncan, No, I don't have any other sourcing and would love to read them too, but Henry's posts were and are always of high interest to me, and in particular this one about the bands. You may remember this old thread, "Maintaining IgM Antibodies for Years, Poor Prognosis in LD" http://www.lymenete...

Henry had posted this information on the thread "Retreatment of LD Patients - Biostat Review:" Look at the date-- 1991. Things have improved since then, especially with regard to Western blots. Current data from the CDC indicates that the 45 kDa, 58 kDa, 66 kDa and 93 kDa are characteristic of late ...