LymeNet Europe

Infect Immun. 1988 August ; 56(8): 1831-1836 Changes in infectivity and plasmid profile of the Lyme disease spirochete, Borrelia burgdorferi, as a result of in vitro cultivation. http://iai.asm.org/cgi/content/abstract/56/8/1831 http://iai.asm.org/cgi/reprint/56/8/1831.pdf T G Schwan, W Burgdorfer a...

CYA? (the pharmacy, I mean) Yeah, maybe. He implied that it was a regulation that was implemented because the pharmacy had no control over how the customer would handle the drug. Stored on a window sill?, top of the fridge?, dashboard of a car? It may be a state regulation, maybe national, I don't ...

From the link: A contested example of a rare exception is a case of renal tubular damage purportedly caused by expired tetracycline (reported by G. W. Frimpter and colleagues in JAMA, 1963;184:111). This outcome (disputed by other scientists) was supposedly caused by a chemical transformation of the...

I'm too busy to look for all the abstracts that Yvonne posted (or others) that might have 'suspicious' funding, but I'm sure they're here. Yes, but we expect better of the Grand High Pooh-Bah. ??????? I don't know of many Lymies who've ever used Pen G. So I'm confused why that's important here. Bic...

This 1996 paper about the dynamics of ceftriaxone and vancomycin was discussed in some detail in a thread about a year ago: http://www.lymeneteurope.org/forum/viewtopic.php?f=5&t=83&p=9890#p9890 There is a link to the full version in that post. You may remember it as the one in which you asked about...

Would it be impudent of me to point out that your first reference quotes of the abstract only are to a 1990 paper that was funded by Glaxo, the manufacturer of cefuroxime (Ceftin)? Or that the implications that you quoted from the abstract are not supported in the fine print of the full text?: "the ...

Applied and Environmental Microbiology, October 2007 , p. 6045-6052, Vol. 73, No. 19 0099-2240/07/$08.00+0 doi:10.1128/AEM.00228-07 Copyright © 2007, American Society for Microbiology. All Rights Reserved. Mixed Infections, Cryptic Diversity, and Vector-Borne Pathogens: Evidence from Polygenis Fleas...

Another mention of in vitro vs in vivo discrepancies. How many of us are beating ourselves up by using an antibiotic that looks good in vitro but has minimal or no activity in vivo? However, the in vitro and the in vivo antibiotic susceptibilities of Bartonella do not correlate well for a number of ...

If Blumenthal's action was so off the wall (unfounded) then why did IDSA settle by agreeing to review and possibly rewrite the Guidelines with fresh authors? And if it was intended by IDSA to be a rubber-stamp operation then why the extended "comment period"? http://www.lymeneteurope.org/forum/viewt...

IMHO the single biggest issue with the 2006 Guidelines is IDSAs refusal to address or even acknowledge late stage relapsing (chronic) Lyme. The evidence for it is overwhelming and the mechanisms are well known; antigenic variation, intracellular location, L-forms (cysts), sequestration in poorly per...