Search found 1104 matches

by Henry
Tue 16 Jul 2019 16:46
Forum: Medical Topics
Topic: Disulfiram: A Test of Symptom Reduction Among Patients With Previously Treated Lyme Disease
Replies: 9
Views: 1036

Re: Disulfiram: A Test of Symptom Reduction Among Patients With Previously Treated Lyme Disease

Actually, alternative approaches are being considered, once one gets beyond the unproven "hang up" of a persistent infection as the one and only mechanism involved : https://medicalxpress.com/news/2019-06- ... tment.html .
by Henry
Tue 16 Jul 2019 16:07
Forum: Medical Topics
Topic: Disulfiram: A Test of Symptom Reduction Among Patients With Previously Treated Lyme Disease
Replies: 9
Views: 1036

Re: Disulfiram: A Test of Symptom Reduction Among Patients With Previously Treated Lyme Disease

We'll see. In contrast to some of the unproven "unorthodox treatments" that have been proposed, the results of a well-conducted placebo-controlled study certainly would be useful in determining whether this --or other drugs-- eliminate the symptoms associated with PTLDS. My concern is the rationale ...
by Henry
Mon 15 Jul 2019 17:37
Forum: Medical Topics
Topic: Disulfiram: A Test of Symptom Reduction Among Patients With Previously Treated Lyme Disease
Replies: 9
Views: 1036

Re: Disulfiram: A Test of Symptom Reduction Among Patients With Previously Treated Lyme Disease

All should be cautioned that it is easy to find LOTS of things that will kill Borrelia in vitro. Rat poison would be an excellent example. However, some of these "drugs" would be much to toxic to even consider using them to treat patients. Also, unless one does placebo-controlled studies, it is impo...
by Henry
Thu 20 Jul 2017 18:26
Forum: General Topics
Topic: Lyme Disease fluorescent microscopy
Replies: 1
Views: 2082

Re: Lyme Disease fluorescent microscopy

Acridine orange (AO) stains nucleic acids present in both DNA and RNA, whether the cells involved are alive or not. AO staining is no proof of viability since dead bacterial cells will stain AO positive as well. Furthermore, all life -- including bacterial life-- requires a minimal amount of genetic...
by Henry
Wed 5 Jul 2017 2:45
Forum: General Topics
Topic: Who do you cheer for in this lawsuit???
Replies: 1
Views: 2249

Re: Who do you cheer for in this lawsuit???

Only a fool would believe anything that ILADS and these scoundrels have to say.
by Henry
Wed 28 Jun 2017 17:28
Forum: Published Studies
Topic: Receptor tyrosine kinases and Lyme disease bacterium Borrelia burgdorferi
Replies: 3
Views: 2744

Re: Receptor tyrosine kinases and Lyme disease bacterium Borrelia burgdorferi

The issue is always whether the results of such in vitro studies are clinically relevant. The same can be said for the results of numerous in vitro studies on persisters. Another major issue in the tyrosine kinase study is whether human cell lines, which really are abnormal cells, are truly represen...
by Henry
Wed 28 Jun 2017 15:56
Forum: Published Studies
Topic: Receptor tyrosine kinases and Lyme disease bacterium Borrelia burgdorferi
Replies: 3
Views: 2744

Re: Receptor tyrosine kinases and Lyme disease bacterium Borrelia burgdorferi

One must be very careful in relating the results of these in vitro studies to events that may occur during human neuroborreliosis acquired naturally. In this study, a cell line ( that may not be typical in all respects to normal human oligodendrocytes) was infected with Borrelia at a MOI of 10:1 -- ...
by Henry
Sun 25 Jun 2017 1:33
Forum: General Topics
Topic: Dr. Cameron
Replies: 7
Views: 3742

Re: Dr. Cameron

Thank you, hv808ct. All of the information that I have posted is in the public domain. None of it comes under the heading of top secret confidential information. After reading it, those who have a few working brain cells will conclude that ILADS is a pseudo-scientific who leadership is dominated by ...
by Henry
Sat 24 Jun 2017 17:42
Forum: Medical Topics
Topic: Chronic Lyme Disease: A Working Case Definition
Replies: 7
Views: 4524

Re: Chronic Lyme Disease: A Working Case Definition

I too sent them a message and received no response. I find all of this to be rather strange and unusual -- to say the least.
I wonder if there really is an issue with using Horowitz's ideas without attribution, i.e., plagiarism?