Search found 100 matches

by TicksSuck
Tue 31 Jul 2012 21:04
Forum: Published Studies
Topic: Persistent Spirochete Antigens in Mice
Replies: 38
Views: 9302

Re: Persistent Spirochete Antigens in Mice

Indeed... (Answering my own question) Presence of infection in 1 of a total of 21 Myd88–/– mice was easily demonstrated by several modalities, including culture of mouse tissues and the ticks used for xenodiagnosis. The failure of antibiotics to eliminate B. burgdorferi from a single Myd88–/– mouse ...
by TicksSuck
Tue 31 Jul 2012 20:29
Forum: Published Studies
Topic: Persistent Spirochete Antigens in Mice
Replies: 38
Views: 9302

Re: Persistent Spirochete Antigens in Mice

B. burgdorferi was not recovered by culture or xenodiagnosis with ticks after antibiotic treatment of WT mice and all but one of the immunodeficient mice with heightened pathogen burden due to impaired TLR responsiveness. Do they mean it was not recovered from any but one of the mice? So, it was re...
by TicksSuck
Tue 10 Jul 2012 20:05
Forum: Published Studies
Topic: Persistent Spirochete Antigens in Mice
Replies: 38
Views: 9302

Re: Persistent Spirochete Antigens in Mice

However, we have so far treated more than 50 mice with ceftriaxone only, using the above-mentioned regimen, and have not found a single spirochete in the cultured samples (Yrjänäinen et al., unpublished results). Ceftriaxone-treated mice have only had positive culture results if they have received ...
by TicksSuck
Tue 10 Jul 2012 19:02
Forum: Published Studies
Topic: Persistent Spirochete Antigens in Mice
Replies: 38
Views: 9302

Re: Persistent Spirochete Antigens in Mice

J Infect Dis. (2007) 196(12): 1866-1867 doi:10.1086/523828 Reply to Wormser et al. and to McSweegan Heta Yrjänäinen, Jukka Hytönen, Xiao-yu R. Song, Jarmo Oks, Kaija Hartiala1 and Matti K. Viljanen To the Editor—We would like to thank Dr. Wormser and colleagues [1], as well as Dr. McSweegan [2], fo...
by TicksSuck
Tue 10 Jul 2012 19:00
Forum: Published Studies
Topic: Persistent Spirochete Antigens in Mice
Replies: 38
Views: 9302

Re: Persistent Spirochete Antigens in Mice

J Infect Dis. (2007) 196(12): 1865-1866 doi:10.1086/523826 Anti-Tumor Necrosis Factor-α Activation of Borrelia burgdorferi Spirochetes in Antibiotic-Treated Murine Lyme Borreliosis: An Unproven Conclusion Gary P. Wormser, Stephen W. Barthold, Eugene D. Shapiro, Raymond J. Dattwyler, Johan S. Bakken...
by TicksSuck
Mon 9 Jul 2012 18:26
Forum: Published Studies
Topic: Persistent Spirochete Antigens in Mice
Replies: 38
Views: 9302

Re: Persistent Spirochete Antigens in Mice

It would be interesting to hear the opinion on Yrjänäinen's studies from those who find Bockenstedt's latest paper so wonderful.
by TicksSuck
Mon 11 Jun 2012 13:39
Forum: Published Studies
Topic: Viable but Non Cultivatible Borrelia and other Pathogens
Replies: 9
Views: 1752

Re: Viable but Non Cultivatible Borrelia and other Pathogens

CultivATIBLE, cultivATABLE or cultivABLE?
by TicksSuck
Fri 1 Jun 2012 4:57
Forum: Lyme Café
Topic: What continent are you from?
Replies: 6
Views: 4187

Re: What continent are you from?

Canada
by TicksSuck
Fri 1 Jun 2012 3:13
Forum: Published Studies
Topic: An Historical Observation on Klempner and Embers
Replies: 26
Views: 3299

Re: An Historical Observation on Klempner and Embers

Henry wrote: What many people do not know is that many antibiotics have anti-inflammatory properties that could relieve certain symptoms (depending on their nature) and cause one to feel better in the absence of a prior persistent infection. The tetracyclines provide a good example of this. For a l...
by TicksSuck
Thu 31 May 2012 20:41
Forum: Published Studies
Topic: An Historical Observation on Klempner and Embers
Replies: 26
Views: 3299

Re: An Historical Observation on Klempner and Embers

This could go on and on and I have other things to do. I don't have anything more to say on the subject. Henry, I find your reply perplexing. You have been going on and on answering many posts which were far from the level of intelligence of the questions here from CO. I (and surely many others) wo...