Chronic/late persistent Lyme borreliosis?

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X-member
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Chronic/late persistent Lyme borreliosis?

Post by X-member » Sat 8 Feb 2014 17:44

I have now explained (in some other places in this forum) that acute stands for early and chronic stands for late (no matter where in the body the infection is located).

But how is a still active/ongoing infection after treatment called?

ILADS:

Chronic Persistent Lyme Borreliosis: PCR Evidence of Chronic Infection Despite Extended Antibiotic Therapy—A Retrospective Review

http://www.ilads.org/lyme_research/lyme_articles9.html

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Re: Chronic/late persistent Lyme borreliosis?

Post by X-member » Sat 8 Feb 2014 17:46

German physicians.

Prolonged antibiotic therapy in PCR confirmed persistent Lyme disease

http://www.grin.com/en/e-book/166179/pr ... me-disease

velvetmagnetta
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Re: Chronic/late persistent Lyme borreliosis?

Post by velvetmagnetta » Sat 28 Mar 2015 4:41

X-member wrote:I have now explained (in some other places in this forum) that acute stands for early and chronic stands for late (no matter where in the body the infection is located).

But how is a still active/ongoing infection after treatment called?

ILADS:

Chronic Persistent Lyme Borreliosis: PCR Evidence of Chronic Infection Despite Extended Antibiotic Therapy—A Retrospective Review

http://www.ilads.org/lyme_research/lyme_articles9.html

How about calling it something I know we can all agree on:

"Chronic-Persistent-Late-Disseminated-Lyme-Neuroborreliosis" or CPLDLNB. :roll:

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Re: Chronic/late persistent Lyme borreliosis?

Post by X-member » Sat 28 Mar 2015 15:35

I agree with both ILADS and German "LLMD:s"!

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Re: Chronic/late persistent Lyme borreliosis?

Post by X-member » Thu 23 Jul 2015 15:42

Evidence assessments and guideline recommendations in Lyme disease: the clinical management of known tick bites, erythema migrans rashes and persistent disease

ILADS, 2014

http://informahealthcare.com/doi/pdf/10 ... 014.940900

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Re: Chronic/late persistent Lyme borreliosis?

Post by X-member » Mon 27 Jul 2015 16:10

ZHANG ON THE HUNT FOR BETTER ANTIBIOTICS TO TREAT CHRONIC PERSISTENT LYME DISEASE

http://lookingatlyme.blogspot.se/2014/1 ... cs-to.html

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Re: Chronic/late persistent Lyme borreliosis?

Post by X-member » Sun 2 Aug 2015 18:07

Chronic Lyme Disease and Co-infections: Differential Diagnosis

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565243/

A quote:
The diagnostic difficulties of Lyme disease and co-infections always concern chronic Lyme disease (late Lyme disease, stage III). The synergic-pathological mechanism requires that co-infections are also present in chronic persistent form.

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Re: Chronic/late persistent Lyme borreliosis?

Post by X-member » Wed 2 Sep 2015 15:47

Chronic Lyme disease: misconceptions and challenges for patient management
Halperin

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440423/

Two quotes (from table 2):
Acute neuroborreliosis (meningitis, radiculitis, cranial neuritis)
Ceftriaxone 2 g/day for 14–21 days or cefotaxime 2 g tid for 14–21 days, or penicillin 24 MU/day ×14–21 days or probably po doxycycline 200–400 mg/day for 21–42 days
Chronic or recurrent neuroborreliosis (eg, treatment failure after first course)
Ceftriaxone 2 g/day for 28 days or cefotaxime 2 g tid for 28 days
Edit to add:

Maybe this (from table 2) also belong in this thread?
Disease resistant to oral treatment
Ceftriaxone 2 g/day for 14–28 days or cefotaxime 2 g tid for 14–28 days, or penicillin 24 MU/day ×14–28 days

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Re: Chronic/late persistent Lyme borreliosis?

Post by X-member » Fri 11 Sep 2015 19:10

The International Lyme and Associated Diseases Society

http://www.ilads.org/lyme/ILADS_Guidelines.pdf

A quote:
Symptoms may continue despite 30 days of treatment (persistent Lyme disease). The patient may relapse in the absence of another tickbite or erythema migrans rash (recurrent Lyme disease), or be poorly responsive to antibiotic treatment (refractory Lyme disease).

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Re: Chronic/late persistent Lyme borreliosis?

Post by X-member » Sun 20 Sep 2015 16:17

Dr Horowitz (facebook):

https://www.facebook.com/drrichardhorow ... 8703458262

A quote:
I presented 4 lectures over the 2 days on an overview of Lyme, co-infections, the MSIDS map, as well as case presentations to illustrate how the MSIDS map can be used in chronic persistent illness.

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