How can the word "chronic" be used?

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http://www.lymeneteurope.org/forum/view ... =30#p41791

A quote (from the post above):

marked by long duration or frequent recurrence : not acute....

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More examples can be found in the thread/post below:

http://www.lymeneteurope.org/forum/view ... 721#p41709

A quote (Norway):

Chronic Lyme borreliosis

Ongoing infection with Borrelia bacterium that has lasted more than 6 months.

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Dr Alan MacDonald, Borrelia Disease, Acute and Chronic, January 2015 Part 1

https://www.youtube.com/watch?v=r6-wzKk8Utg

In this video (7.22 min) Dr Alan B MacDonald explain what the word "chronic" (in chronic borreliosis) stands for.

Part 2 (if someone is interested):

Dr Alan MacDonald, Borrelia Disease, Acute and Chronic Part 2 January 2015

https://www.youtube.com/watch?v=PZXL3UUa4mY

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Chronic or Late Lyme Neuroborreliosis: Analysis of Evidence Compared to Chronic or Late Neurosyphilis

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551238/

A quote:

Importantly, the existence of late Lyme disease is approved by all official guidelines in the U.S., Canada and Europe. The terms “late” and “chronic” Lyme disease, as in syphilis, are synonymous and define tertiary Lyme disease. The use of “chronic” Lyme disease as a different entity is inaccurate and confusing.

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It is our belief that the vast majority of chronic bacterial infections are biofilms.

Garth Ehrlich, PhD, has been examining how chronic infections persist* despite of antimicrobial treatment.

Watch his interesting interview:

Dr. Garth Ehrlich - Twenty Years of Biofilm Research

https://www.youtube.com/watch?v=OK-6B2J-si0

Information about how the word "persistent" can be used can be found in the thread below:

How can the word "persistent" be used?

http://www.lymeneteurope.org/forum/view ... =11&t=5732

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I have not yet found any physician that use chronic Lyme borreliosis only in the meaning of persistent active borreliosis after treatment and include cases that still have an early persistent borreliosis after treatment in this group.

But a treatment failure in an early stage, can (of course) become a late (chronic) infection if the patient don't get more treatment when the infection still is in an early stage.

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I found this question in another thread:

I would be very interested to know to what extent it has been known that Lyme can be a chronic infection.

This have been known for many, many years.

Chronic Lyme disease: misconceptions and challenges for patient management
John J Halperin

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440423/

A quote:

Untreated infection, particularly with joint involvement, can be chronic, lasting years.

I also give you some information about European borreliosis from EUCALB:

http://www.eucalb.com/

Two quotes:

Lyme arthritis is rare in Europe but is more frequently seen in north America....

Acrodermatitis chronica atrophicans (ACA)
Is an unusual progressive fibrosing skin lesion which is probably the most common manifestation of chronic Lyme borreliosis in Europe.

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Treating Chronic Lyme, Dr. Burrascano

http://forums.prohealth.com/forums/inde ... no.136739/

Two quotes:

J. J. Burrascano, MD April 24, 2004

. Early Lyme Disease ("Stage I")
- At or before the onset of symptoms
- Can be cured if treated properly

. Disseminated Lyme ("Stage II")
- Multiple major body systems affected
- More difficult to treat

. Chronic Lyme Disease ("Stage III")
- Ill for one or more years
- Serologic tests less reliable
- Treatment must be more aggressive and of longer duration

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Chronic Neurologic Manifestations of Lyme Disease
Eric L. Logigian, M.D., Richard F. Kaplan, Ph.D., and Allen C. Steere, M.D.
N Engl J Med 1990; 323:1438-1444November 22, 1990DOI: 10.1056/NEJM199011223232102

http://www.nejm.org/doi/full/10.1056/ne ... 1223232102

IDSA call this Late Neurologic Lyme Disease.

http://www.idsociety.org/uploadedfiles/ ... isease.pdf

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Public health impact of strain specific immunity to Borrelia burgdorferi

By Khatchikian CE, et al. • http://www.ProHealth.com • November 20, 2015

http://www.prohealth.com/library/showar ... ibid=21842

A quote:

Editor’s Note: Most Lyme-literate researchers and doctors do not believe that it is possible to acquire immunity to Borrelia burgdorferi through early treatment of Lyme. This study involves at least one researcher whose interests represent the Infectious Diseases Society of America (IDSA), which has biased and flawed guidelines for the treatment of chronic Lyme disease. The study may therefore be based upon an unproven premise.