33% treatment failure in late Lyme borreliosis?

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33% treatment failure in late Lyme borreliosis?

Post by X-member » Sun 31 Jul 2016 16:20

Chronic Lyme Article from 1987...?

http://www.lymeneteurope.org/forum/view ... 716#p41716

hv808ct posted this in the thread above:
Regarding the 1987 article, it reports 3 untreated cases that were eventually diagnosed and treated.
The first case occurred during 3/82—6/85 and was treated with 2wk of iv pen.
The 2nd case occurred during 9/83--3/86 and was treated with 2wk of iv pen.
The 3rd case occurred during 8/83--1/84. Overt ACA was treated with 4wk of oral pen. Subsequent complications occurred between 3/85--5/85 and were resolved with iv pen.
Last edited by X-member on Sun 31 Jul 2016 16:50, edited 1 time in total.

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Re: 33% treatment failure in late Lyme borrelios?

Post by X-member » Sun 31 Jul 2016 16:27

Systemisk Borreliose og langtidsplager (Dr Eikeland, Norway)

(Systemic Borreliosis and long-term ailments)

http://xn--flttsenteret-ucb.no/wp-conte ... 140116.pdf

A quote:
200 patients

• 60 % did not have LB
• 16 % had a form of localized or disseminated LNB
• 17 % were diagnosed with probable/questionable PTLBS
8 % were diagnosed with probable/questionable continuing Borrelia infection

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Re: 33% treatment failure in late Lyme borrelios?

Post by X-member » Sun 31 Jul 2016 16:34

Invincible borrelia?

http://www.lymeneteurope.org/forum/view ... 175#p44306

A quote:
This means that treatment failures and relapses occur in Sweden and are treated with abx.

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Re: 33% treatment failure in late Lyme borrelios?

Post by X-member » Sun 31 Jul 2016 16:46

Diagnosis and Treatment of Lyme borreliosis
Deutsche Borreliose-Gesellschaft e. V.


http://www.borreliose-gesellschaft.de/T ... elines.pdf

A quote:
In the early stage, i. e. in the first 4 weeks after the start of infection, a failure rate of 10% is to be expected with antibiotic treatment. (121/135)
In the chronic forms, it is significantly higher at up to 50%. (30/31/52/55/74/99/121)

Even earlier studies referred to the problem area of chronic Lyme borreliosis and the limits of its susceptibility to treatment. (31/55/59/61/62/65/92/94/121/138) In all these studies, the duration of treatment was generally limited to a maximum of four weeks. Considerable therapeutic failure rates occurred under these conditions, even with repeated courses of treatment. (78/82/90)

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Re: 33% treatment failure in late Lyme borreliosis?

Post by X-member » Mon 1 Aug 2016 14:24

Norway (Dr Eikeland), a translated quote:
Re-treatment after new objective signs/findings ..
http://xn--flttsenteret-ucb.no/wp-conte ... 140116.pdf

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Re: 33% treatment failure in late Lyme borreliosis?

Post by X-member » Tue 2 Aug 2016 0:45

Invincible borrelia?

http://www.lymeneteurope.org/forum/view ... =10#p44316

Henry wrote:
X-member: Oh yes, I agree. However, such patients are extremely difficult to find.
Let us say that treatment failure is only 1% (I think that is what professor Björn Olsen at the center for vector-borne infections in Uppsala, Sweden have said in media) and in Sweden 40 000 people are diagnosed with borreliosis/year.

Then there are 400 Swedish patients with treatment failure every year to do studies on.

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