Tick Transmitted Spongioform (Prion) Brain Disease

Topics with information and discussion about published studies related to Lyme disease and other tick-borne diseases.
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inmacdonald
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Tick Transmitted Spongioform (Prion) Brain Disease

Post by inmacdonald » Tue 28 Feb 2012 22:27

Spiroplasma ( spiral mycoplasma) transmitted by ticks - Spongioform Brain Disease - Role of Cell Wall Deficient organism (CWD) and Chronic Wasting Disease (CWD) in mammals
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2007 Spiroplasma Transmissible by Ticks Part 0 Title.jpg
Title
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2007 Spiroplasma Transmissible by Ticks Fig 1d  Enlarged -Electron Microscopy.jpg
Electron Microscopy
ElectronMicroscopy profile of the CWD -Fig 1d in original article
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2007 Spiroploasma Transmissible by Ticks Fig 3.jpg
Figure 3 - original article
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Alan B. MacDonald, MD
Feb 28,2012
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inmacdonald
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Re: Tick Transmitted Spongioform (Prion) Brain Disease

Post by inmacdonald » Tue 28 Feb 2012 22:34

2007 Article

Link: http://jmm.sgmjournals.org/content/56/9 ... l.pdf+html

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2007 Spiroploasma Transmissible by Ticks Part 1 abstract.jpg
Abstract
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Alan B. MacDonald MD
Feb 28,2012
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Re: Tick Transmitted Spongioform (Prion) Brain Disease

Post by inmacdonald » Tue 28 Feb 2012 22:41

March 2012 - CDC - Emerging Infectious Diseases
Link to full text article:
http://wwwnc.cdc.gov/eid/article/18/3/1 ... rticle.htm
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20121 CWD Part 1 - Energing Infect Dis.jpg
Title and Authors
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20121 CWD Part 2 - Emerging Infect Dis.jpg
Abstract
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2012 CWD part 3 - Emerging Infect Dis.jpg
Discussion - continued
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Alan B. MacDonald MD
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Re: Tick Transmitted Spongioform (Prion) Brain Disease

Post by inmacdonald » Tue 28 Feb 2012 22:47

Chronic Wasting Disease - Due to Prion Infection- and the role of Cell Wall Deficient organisms (CWD)
in its pathogenesis

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Link : 2009 article

Given that prion disease in humans can be difficult to diagnose and the asymptomatic incubation period can last decades, continued research, epidemiologic surveillance, and caution in handling risky material remain prudent as CWD continues to spread and the opportunity for interspecies transmission increases. Otherwise, similar to what occurred in the United Kingdom after detection of variant CJD and its subsequent link to BSE, years of prevention could be lost if zoonotic transmission of CWD is subsequently identified,


Link:

Link : 2009 Transmissible spongioform encephalopathy

http://www.neurology.org/content/72/3/2 ... l.pdf+html

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Alan B. MacDonald, MD
February 28, 2012
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Re: Tick Transmitted Spongioform (Prion) Brain Disease

Post by inmacdonald » Tue 28 Feb 2012 23:30

CWD

CWD have perennially ( since the Era of Dr Lida Mattman) indicated "Cell Wall Deficient" organisms

Now we encounter another cypher for "CWD" -----namely Chronic Wasting Disease--------

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Dr Lida Mattman's monograph - CRC Press - Third Edition - - Cell Wall Deficient Forms--Stealth Pathogens
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Cell Wall Deficient Forms - Stealth Pathogens - 3rd edition - CRC Press
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Tom Grier on Dr. Lida H. Mattman

link:

http://www.lymeneteurope.org/info/notes ... ient-forms
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Alan MacDonald's comment -
Dr Lida Mattman was a brilliant, visionary, microbiologist who educated
generations of Medical students as Professor of Microbiology, at the Wayne State School of Medicine.
She was very kind to young investigators in the field of clinical microbiology. It was a delight to speak
with her and to share ideas about Cell Wall Deficient microbes and their contributions to human diseases which were in the realm of "idiopathic diseases" . She spoke a number of languages. We would sometimes converse in French. She would challenge ideas, some new and some old and established with the question
"Pourquoi?". Dr Mattman was nominated several times for the Nobel Prize in Medicine by her colleagues.
In our collective hearts she had already won the Medal.
Mainstream microbiology never fully appreciated her genius. We now read in the words of the
Centers for Disease Control and Prevention, that Dr. Mattman'[s convictions and her writings, and Images
in her textbook are indeed the key to an understanding of "idioopathic" diseases, in this present case,
the etiology of Spongioform Brain Degeneration, the most feared disease by pathologists who are obligated
to handle Autopsy brain tissues from patients who die from Creutzfeldt Jakob Disease, can now be attributed to a Cell Wall Deficient microbe; A microbe ( Dr Pruisner's exhortations notwithstanding)
which has a DNA genomic signature; and a microbe which has a key role in the production of Misfolded
proteins PrP(sc).
Thank you Dr Mattman, for your scholarship, your leadership, and your kindness.
Alan B. MacDonald MD

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Alan B. MacDonald MD
Feb 28,2012

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Re: Tick Transmitted Spongioform (Prion) Brain Disease

Post by inmacdonald » Thu 1 Mar 2012 19:08

Dialogue between Dr Brenner and Dr Brown following publication of

Neurology 2008
Title 2008 Transmissible spongioform encephalopathy in the 21st century Neuroscience for the clinical neurologist.jpg
Title
Title 2008 Transmissible spongioform encephalopathy in the 21st century Neuroscience for the clinical neurologist.jpg (24.35 KiB) Viewed 3171 times
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Please refer to the PDF file attached below:

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Spiroplasmas resistance profiles.jpg
Spiroplasmas resistance profiles
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Attachments
Neurology - Spongioform Disease - 2008 - Remarks post publication.pdf
Author's remarks post publication 2008
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