Incidence of Bbsl infection after tick bite in Sweden & Åland Islands, Finland

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RitaA
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Incidence of Bbsl infection after tick bite in Sweden & Åland Islands, Finland

Post by RitaA » Sun 6 Sep 2015 22:19

http://www.ncbi.nlm.nih.gov/pubmed/26341726
Ticks Tick Borne Dis. 2015 Aug 22. pii: S1877-959X(15)30006-6. doi: 10.1016/j.ttbdis.2015.08.009. [Epub ahead of print]

A prospective study on the incidence of Borrelia burgdorferi sensu lato infection after a tick bite in Sweden and on the Åland Islands, Finland (2008-2009).

Wilhelmsson P1, Fryland L2, Lindblom P1, Sjöwall J3, Ahlm C4, Berglund J5, Haglund M6, Henningsson AJ7, Nolskog P8, Nordberg M9, Nyberg C9, Ornstein K10, Nyman D9, Ekerfelt C11, Forsberg P12, Lindgren PE13.

Author information

1 Medical Microbiology, Department of Clinical and Experimental Medicine, Linköping University, 581 85 Linköping, Sweden.
2 Infectious Diseases, Department of Clinical and Experimental Medicine, Linköping University, 581 85 Linköping, Sweden; Clinical Immunology, Department of Clinical and Experimental Medicine, Linköping University, 581 85 Linköping, Sweden. Electronic address: linda.fryland@liu.se.
3 Department of Infectious Diseases and Department of Clinical and Experimental Medicine, Linköping University, 581 85 Linköping, Sweden.
4 Division of Infectious Diseases, Department of Clinical Microbiology, Umeå University, 901 85 Umeå, Sweden.
5 School of Health Science, Blekinge Institute of Technology, 371 79 Karlskrona, Sweden.
6 Department of Infectious Diseases, Kalmar County Hospital, 381 95 Kalmar, Sweden.
7 Department of Clinical Microbiology, Division of Medical Services, Ryhov County Hospital, 551 85 Jönkoping, Sweden.
8 Department of Communicable Disease Control and Prevention, Region Västra Götaland, Skaraborg Hospital, 541 85 Skövde, Sweden.
9 The Åland Group for Borrelia Research, Mariehamn, Åland, Finland.
10 Department of Internal Medicine, Hässleholm Hospital, 281 38 Hässleholm, Sweden; Department of Clinical Sciences, Lund University, 221 00 Lund, Sweden.
11 Clinical Immunology, Department of Clinical and Experimental Medicine, Linköping University, 581 85 Linköping, Sweden.
12 Infectious Diseases, Department of Clinical and Experimental Medicine, Linköping University, 581 85 Linköping, Sweden; Department of Infectious Diseases and Department of Clinical and Experimental Medicine, Linköping University, 581 85 Linköping, Sweden.
13 Medical Microbiology, Department of Clinical and Experimental Medicine, Linköping University, 581 85 Linköping, Sweden; Department of Clinical Microbiology, Division of Medical Services, Ryhov County Hospital, 551 85 Jönkoping, Sweden.

Abstract

Lyme borreliosis (LB) is a common and increasing tick-borne disease in Europe. The risk of acquiring a Borrelia infection after a tick bite is not fully known. Therefore, we investigated the incidence of Borrelia infection after a bite by a Borrelia-infected tick and if the Borrelia load and/or the duration of tick-feeding influenced the risk of infection. During 2008-2009, ticks and blood samples were collected from 1546 tick-bitten persons from Sweden and the Åland Islands, Finland. Follow-up blood samples were taken 3 months after the tick bite. The duration of tick feeding was microscopically estimated and Borrelia was detected and quantified in ticks by real-time PCR. Anti-Borrelia antibodies were detected in sera using ELISA tests and immunoblot. Five percent (78/1546) of the study participants developed Borrelia infection (LB diagnosis and/or seroconversion) after a tick bite (45% bitten by Borrelia-infected ticks and 55% bitten by uninfected ticks). Of these, 33 developed LB (whereof 9 also seroconverted) while 45 participants seroconverted only. Experience of non-specific symptoms was more frequently reported by Borrelia-infected participants compared to uninfected participants. All who seroconverted removed "their" ticks significantly later than those who did not. The Borrelia load in the ticks did not explain the risk of seroconversion. Regional and sex differences in the Borrelia seroprevalence were found. The risk of developing a Borrelia infection after a bite by a Borrelia-infected tick is small but increases with the duration of tick feeding.

Copyright © 2015 Elsevier GmbH. All rights reserved.

KEYWORDS:

Asymptomatic infection; Bacterial load; Borrelia burgdorferi sensu lato; Lyme borreliosis; Tick bite; Tick-feeding

PMID: 26341726 [PubMed - as supplied by publisher]

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ChronicLyme19
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Re: Incidence of Bbsl infection after tick bite in Sweden & Åland Islands, Finland

Post by ChronicLyme19 » Mon 21 Sep 2015 21:24

All who seroconverted removed "their" ticks significantly later than those who did not.
I wonder how much longer it was, minutes, hrs, days, weeks?
Half of what you are taught is incorrect, but which half? What if there's another half missing?

X-member
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Re: Incidence of Bbsl infection after tick bite in Sweden & Åland Islands, Finland

Post by X-member » Wed 24 Feb 2016 18:03

NordTick 2016 Conference

http://www.lymediseaseaction.org.uk/lat ... onference/

A quote:
Knut Eirik Eliassen described a study investigating the incidence of tick bites and EM in 4 Norwegian counties. They reported an average incidence of EM of 449/100,000 inhabitants – much higher than they had expected.

lou
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Re: Incidence of Bbsl infection after tick bite in Sweden & Åland Islands, Finland

Post by lou » Fri 26 Feb 2016 19:26

And I wonder how long these people were followed. It was more than two years after my tickbite that the roof fell in on me symptom-wise. Before that there were odd small things, like a knee that wouldn't bend very well, and once in a while a burning sensation in one place only in my skin. Very few doctors would have suspected or treated this. If such a thing occurred in this study, would they have said it was unrelated at the time?

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Re: Incidence of Bbsl infection after tick bite in Sweden & Åland Islands, Finland

Post by X-member » Sat 27 Feb 2016 0:05

This article from Finland is in Swedish.

"Skjutna rådjur minskar inte fästingburna sjukdomar"

http://svenska.yle.fi/artikel/2015/06/2 ... -sjukdomar

Professor Dag Nyman, Åland a translated quote:
Borrelia bacteria can for a long time be silent and still in the body. Then they are not dangerous and do no harm. But if you get symptoms it should be investigated. Have you been to borreliosis areas it is natural to investigate whether it could be borreliosis that causes the symptoms, says Nyman.

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