Active neuroborreliosis or inflammation: are the diagnostic guidelines at stake?

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Active neuroborreliosis or inflammation: are the diagnostic guidelines at stake?

Post by X-member » Sun 23 Dec 2018 12:55

Acta Neurol Belg. 2018 Dec 17. doi: 10.1007/s13760-018-01067-2. [Epub ahead of print]

Active neuroborreliosis or inflammation: are the diagnostic guidelines at stake?

De Cauwer H1,2, Lagrou K3, Coeckelbergh E4,5, Bogaerts A6, Leenders J4, Vanneste D7,8.

Abstract
Neuroborreliosis can induce a variety of neurological syndromes: e.g., cranial neuritis, plexitis, radiculitis, meningitis, cerebellitis, … We report on five cases of patients with a diagnosis of neuroborreliosis based on clinical symptoms, serologic tests and MR imaging results. However, neither of them fulfils the diagnostic criteria for definite neuroborreliosis. Are the diagnostic criteria still valid or is there a need to revise them? Is our diagnosis correct? Are these cases post-Lyme auto-immune neuronal inflammation, and not due to still active spirochetal infection? Do we need to consider immunosuppressive therapy instead of third-generation cephalosporins?

KEYWORDS:
Diagnostic criteria; Differential diagnosis; MR imaging.; Myelitis; Neuroborreliosis

PMID: 30556097 DOI: 10.1007/s13760-018-01067-2
https://www.ncbi.nlm.nih.gov/pubmed/30556097

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