Blumenthal Announces Grant for Lyme Disease Testing

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phyfe
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Blumenthal Announces Grant for Lyme Disease Testing

Post by phyfe » Fri 8 Aug 2014 18:24

http://wnpr.org/post/blumenthal-announc ... se-testing
Blumenthal Announces Grant for Lyme Disease Testing
By Heather Brandon

Sen. Richard Blumenthal, at right, reviews an intake questionnaire in 2011 at the Western Connecticut Health Network Lyme Disease Registry, alongside Amber Butler and Ramin Ahmadi (file photo).

U.S. Senator Richard Blumenthal announced on Wednesday a $600,000 federal grant to improve testing for Lyme disease.

The Connecticut Democrat made the announcement in Danbury alongside researchers from Western Connecticut Biomedical Research Institute and the Seattle-based RareCyte, Inc.

Blumenthal's office said Lyme disease affects some 300,000 Americans each year, and that Connecticut has among the largest number of reported cases.

Many of the current tests used to detect Lyme disease can give false negative results early in the course of the illness, leading to delayed treatment. Blumenthal's office said that better testing will enable earlier detection and better treatment of the disease.

The ailment is named after Lyme, Connecticut, where it was first identified in 1975.

Camp Other
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Re: Blumenthal Announces Grant for Lyme Disease Testing

Post by Camp Other » Fri 8 Aug 2014 19:47

I tweeted this recently. I'm interested in hearing more about this test because I get the impression they are looking to develop a test that is similar to one used for dogs in detecting Lyme disease. Also, I get the impression that they're working on a direct detection test.

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Re: Blumenthal Announces Grant for Lyme Disease Testing

Post by Camp Other » Fri 8 Aug 2014 19:56

This link contains more detailed info:

http://www.stamfordplus.com/stm/informa ... 2040.shtml
The scientists have developed an assay method for direct visualization of the Lyme infection in blood that combines RareCyte’s density-based separation and enrichment technology for rare cells with immunofluorescence microscopy. The assay could have significant impact on the state of current Lyme disease diagnostics.
Ron Seubert, CEO of RareCyte, Inc stated, “We are extremely pleased with our fruitful collaboration with Dr. Paul Fiedler and his group at the WCHN Biomedical Research Institute. Development of more sensitive and accurate methods of direct detection of Borrelia burgdorferi for the purpose of diagnosing Lyme disease patients is a high-priority area of interest for NIAID.
...RareCyte, analyzed blood samples of a small cohort of patients clinically diagnosed with acute Lyme disease using RareCyte technology before, during and after antibiotic treatment. In all patients, B.burgdorferi-positive staining objects were identified in the blood. In some cases the positive staining objects persisted even after antibiotic treatment had been completed. “Based on these preliminary results, we see a potential for monitoring symptomatic patients for response to antibiotic therapy as well. However, the RareCyte assay for Lyme disease detection requires further development and study before it can be made available for routine clinical use. The SBIR grant will support that effort,” said Dr. Kaldjian.
The research will be supported by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health under Award Number R43AI113990.
Press Release on the RareCyte website:

http://rarecyte.com/news-events.html?ref=16

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