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Severity criteria

Posted: Wed 16 Aug 2017 17:53
by ta2Ed
Dear collegues.
I need info on criteria of severity for acute Lyme.
I would be grateful for any clarifications.

Re: Severity criteria

Posted: Thu 17 Aug 2017 22:13
by lou
It is not clear what you are asking for. I have never heard of anything like this that would measure severity. Sometimes it is said that there are several stages, with acute being the first stage. This is based on syphilis which is said to have several stages, and is also a spirochete, so that is probably where it came from.

Acute usually means the early stage, just after being bitten. How long that lasts is subject to differing opinions. Some say if it is treated within the first year, you still have a good chance. Others don't believe the window of opportunity lasts that long and a study ongoing at a U.S. university said that even many people who are treated early may still continue to have symptoms. I won't go into all the opinions on the subject, except to say that late stages can still respond to treatment.

An informal way, nothing said officially, of thinking of severity of acute disease is how many different symptoms you have. Once it becomes disseminated, usually the symptoms increase in frequency and kind. However, just having one severe symptom could ruin a person's day.

Maybe you could tell us more about what you are looking for when you asked this question.

Re: Severity criteria

Posted: Sun 27 Aug 2017 19:05
by ta2Ed
OK. I am a laboratory specialist and I process laboratory data of a group of acute patients. I need some criteria for separating the cohort into inapparant, light, medium and heavy forms.
I did not find any clear landmarks in the literature, so I asked the question here.

Re: Severity criteria

Posted: Mon 28 Aug 2017 21:20
by lou
I see. Not being a lab person, not sure how to reply. I guess it depends on what kind of test this is, as to whether you could quantify severity. Some kinds are said to be either positive or negative, others do have gradations, as I understand it. You would be better off talking to other lab people about the specific kind of test you are using. I have sent you an email with the contact information for a U.S. lab. There are some in Germany too, but I don't have those addresses.