Intracellular Borrelia

General or non-medical topics with information and discussion related to Lyme disease and other tick-borne diseases.
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inmacdonald
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Re: Intracellular Lyme

Post by inmacdonald » Sun 29 Jan 2012 23:43

Intracellular Residence of Borrelia within Neurons and Central Nervous System Cells (human)
From the manuscripts of Judith Miklosssy MD PhD

Dr Judith Miklosssy has demonstrated ( with the use of specific Monoclonal antibodies to Borrelia
species (OSP A) that intradellular forms of Borrelia are present withiin diseased Human tissues:

From her PhD thesis in 2005 Figure

http://www.miklossy.ch/media/83fcb06de3 ... a86321.pdf


From her PhD thesis in 2008: (fiure 7 i) (figure 7h)

http://www.ncbi.nlm.nih.gov/pmc/article ... 4-5-40.pdf

http://www.ncbi.nlm.nih.gov/pmc/article ... 4-5-40.pdf
Attachments
Choroid plexus cell with spirochete - Miklosssy 2008 Fig 7.jpg
Human Choroid plexus cell (Figure 7h)
Choroid plexus cell with spirochete - Miklosssy 2008 Fig 7.jpg (19.51 KiB) Viewed 4363 times
Miklossy 2008 Intracellular spirochete cortical neuron Immunostain(arrow)Fig7.jpg
Human Cortical Pyramidal neuron - Intracellular borrelia -immunostain OspA (Figure 71)
Miklossy 2008 Intracellular spirochete cortical neuron Immunostain(arrow)Fig7.jpg (12.62 KiB) Viewed 4363 times
Miklossy Rat Neuron with Intracellular Borrelia Fig7  i.jpg
Intracellular Borrelia within a Rat Neuron( Figure )
Miklossy Rat Neuron with Intracellular Borrelia Fig7 i.jpg (4.5 KiB) Viewed 4367 times

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Re: Intracellular Lyme

Post by X-member » Mon 30 Jan 2012 12:42

Very interesting! Thank you!

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Re: Intracellular Lyme

Post by X-member » Mon 20 Feb 2012 21:22

More info about intracellular borrelia in the topic below:

"Segmentation in the Borrelia Genome Genetic Implications"

http://www.lymeneteurope.org/forum/view ... 686#p27068

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Re: Intracellular Borrelia

Post by X-member » Thu 20 Sep 2012 15:57

"Chronic persistent Lyme Disease (LD) or chronic Borreliosis"

http://www.borreliose-nachrichten.de/wp ... liosis.pdf

A quote:
In case of a chronic infection, it can take several hours or even days until they* are visible under the microscope, as they “slip out” of the cells (erythrocytes and macrophages).
* The spirochetes

dorothy de kok
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Re: Intracellular Borrelia

Post by dorothy de kok » Sat 10 Nov 2012 16:36

Hi all

After gently 'breaking open' the perfect-looking red blood cells of a person with ongoing symptoms of Lyme Disease (even after extended courses of antibiotics which are supposed to clear the infection), it does not take long before many spirochetes and other microbes are clearly visible with a phase contrast condenser.
What some classify as Post Lyme Syndrome, is nothing more that continuing infection resulting in continuing symptoms.
Textbook staining of spirochetes is also problematic as there is nothing to stain. All is hidden, but CAN be revealed, with a little effort and some practice.


http://youtu.be/S7TiMtpuRXo

dorothy de kok
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Re: Intracellular Borrelia

Post by dorothy de kok » Sat 10 Nov 2012 16:53

Sorry about above link.

I hope this one works better.

http://www.youtube.com/watch?feature=pl ... M9ZruVX5Zs

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inmacdonald
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Re: Intracellular Borrelia

Post by inmacdonald » Mon 12 Nov 2012 15:55

IN VIVO
Images of Borrelia burgdorferi
Inside of Living Cells
IN VIVO evidence of the Image type
[with bonus images of IN VIVO Treponema pallidum in intracellular
sites inthe living rabbit - see the PDF file)
________________________________________----

Judith Miklossy MD PhD DSC

link: [PDF file with multiple intracellular images)
https://www.dropbox.com/s/ue8aa4xuo0a7y ... 9_2007.pdf
______________________________

Alan B. MacDonald MD:

Images of Borrelia burgdorferi inside the cytoplasmic compartment of living
human neurons in Alzheimer's Disease:
Intracellular Bb Alzheimer brain.jpg
Intracellular Borrelia burgdorferi inside the cytoplasmic compartment of human neurons 2 Alzheimer's Disease
Intracellular Bb Alzheimer brain.jpg (98.17 KiB) Viewed 4144 times
Intracellular Spirochetal DNA inside alzheimer nerons.jpg
Intracellular DNA of borreliaburgdorferi inside of the cytoplasmic compartment of human neuron from Alzheimers Disease
Intracellular Spirochetal DNA inside alzheimer nerons.jpg (136.49 KiB) Viewed 4144 times
Conclusion:

IN VIVO evidence is presented for Borrelia burgdorferi to localize
INTRACELLULARLY 9within cytoplasmic compartment of living cells - Neurons of
Alzheimer's Disease obtainefrom fresh frozen antthen thawed whole brains
from Alzheimer's disease obtained from the Harvard University Brain Bank.

Respectfully<
A

PS: Note also the image evidence for In vivo Intracellular location of Treponema pallidum
within Rabbit cells in Experimental Laboratory induced Syphilis via intratesticular
or by intradermal inoculation- Institut Alfred Fournier - Professor Pierre Collart MD.

dorothy de kok
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Re: Intracellular Borrelia

Post by dorothy de kok » Tue 13 Nov 2012 17:10

Absolutely beautiful images.

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Re: Intracellular Borrelia

Post by X-member » Thu 19 Dec 2013 17:10

From Sweden:

Zoonoser med fokus på fästingburna zoonoser
Ingvar Eliasson, klinisk bakteriolog
Klinisk mikrobiologi, Laboratoriemedicin NU-sjukvården


http://www.mikrobiologi.net/patogenes20 ... onoser.pdf

A google translated quote from page 23:
Immunological escape (immune evasion)
a) phase and antigenic variation
b) hiding in immunologically low-active compartments (immune
privileged sites) for example, brain, joints, intracellular etc
(c) Cyst-and/or bleb formation)

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inmacdonald
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Re: Intracellular Borrelia

Post by inmacdonald » Thu 26 Dec 2013 18:14

Intracellular Borrelia: Human Autopsy evidence:


Not Just In TISSUE CULTURE MODELS bu also IN VIVO to:

_________________________-
Intraneuronal composite Miklossy and MacDonald.jpg
Intra neuronal IN ViVo [In Human] autopsy
Intraneuronal composite Miklossy and MacDonald.jpg (77.42 KiB) Viewed 3767 times
________________________


Cystic borrelia Invade Human Neuron cells - Autospy Study:
____________________________________
Cyst  invades human neuron Alz dis.jpg
Borrelia Cyst invades autopsy human neuron cell
Cyst invades human neuron Alz dis.jpg (74.05 KiB) Viewed 3767 times

Respectfully,
Alan B. MacDonald MD FCAP FASCP
December 26, 2013

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