http://www.efns.org/fileadmin/user_uplo ... liosis.pdf
And now, Halperins information again:Duration of treatment
There are no comparative controlled studies of treatment
length in European late LNB. A recent American openlabel
randomized comparison (class III) of 14-day vs.
28-day treatment with ceftriaxone (2 g daily) for late
Lyme borreliosis (143 patients, of whom a third with
neurological symptoms) showed similar cure rates (76%
and 70%, respectively) after 1 year, and there were more
discontinuations as a result of adverse events in the 28-
day group . Another series (class IV) of late LNB
showed disappearance of symptoms in 69/79 (87%) after
100 days regimens with various antibiotics, whereas
14 days with ceftriaxone cured four of 13 (31%) .
A quote (from: "17.6 Treatment – The Myth that More
(and more and more…) is Better"):
Does it look like Halperin is talking about late (stage 3) neuroboreliosis?Numerous studies have now shown that Lyme disease – even in the presence of
nervous system infection – can readily be treated with fairly short courses of conventional antibiotics.