Lyme Disease News & Current Medical Research

The latest publications of scientific medical research, articles and news on Lyme disease from many resources are automatically displayed here.

List of latest Lyme news and medical research

Friday 25 November 2022

Molecular Testing for Diagnosis of Early Lyme Disease

Am J Clin Pathol. 2022 Aug 10:aqac080. doi: 10.1093/ajcp/aqac080. Online ahead of print.NO ABSTRACTPMID:35946458 | DOI:10.1093/ajcp/aqac080 (Source: American Journal of Clinical Pathology)


Friday 25 November 2022

Systematic Review and Meta-analysis of Lyme Disease Data and Seropositivity for Borrelia burgdorferi, China, 2005 ‒2020

Emerg Infect Dis. 2022 Dec;28(12):2389-2397. doi: 10.3201/eid2812.212612.ABSTRACTSince its initial identification in 1986, Lyme disease has been clinically diagnosed in 29 provinces in China; however, national incidence data are lacking. To summarize Lyme disease seropositivity data among persons across China, we conducted a systematic literature review of Chinese- and English-language journal articles published during 2005‒2020. According to 72 estimates that measured IgG by using a diagnostic enzyme-linked assay (EIA) alone, the seropositivity point prevalence with a fixed-effects model was 9.1%. A more conservative 2-tier testing approach of EIA plus a confirmatory Western immunoblot (16 estimates) yielded seropositivity 1.8%. Seropositivity by EIA for high-risk exposure populations w...

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Friday 25 November 2022

Neuroborreliosis in India - A Diagnostic Challenge and a Great Mimicker: A Case Series

CONCLUSION: Lyme's disease, a common disease of the west does exist in the Indian subcontinent as well. Because of increasing global travel and migration and change in vector habitat the disease seems to have percolated in the non endemic areas too. Proper history of travel or exposure to tick bite is important. We want to emphasize, Neuroborreliosis, a great mimicker may have diverse and varied neurological presentations and has a potential for reversibility with appropriate treatment even after a significant delay in diagnosis.PMID:35598127 (Source: Journal of the Association of Physicians of India)


Friday 25 November 2022

Epidemiology of Lyme borreliosis based on outpatient claims data of all people with statutory health insurance, Germany, 2019

ConclusionsThese findings serve as a solid basis for regionally tailored population-based intervention programmes and can support modelling studies assessing the development of LB epidemiology under various climate change scenarios. (Source: Eurosurveillance)


Friday 25 November 2022

Economic Burden of Reported Lyme Disease in High-Incidence Areas, United States, 2014-2016

Emerg Infect Dis. 2022 Jun;28(6):1170-1179. doi: 10.3201/eid2806.211335.ABSTRACTApproximately 476,000 cases of Lyme disease are diagnosed in the United States annually, yet comprehensive economic evaluations are lacking. In a prospective study among reported cases in Lyme disease-endemic states, we estimated the total patient cost and total societal cost of the disease. In addition, we evaluated disease and demographic factors associated with total societal cost. Participants had a mean patient cost of ≈$1,200 (median $240) and a mean societal cost of ≈$2,000 (median $700). Patients with confirmed disseminated disease or probable disease had approximately double the societal cost of those with confirmed localized disease. The annual, aggregate cost of diagnosed Lyme disease could be $3...


Friday 25 November 2022

001 An unusual cause of lymphocytic meningitis

A 36-year-old Spanish man, with a background of ketamine use, presented with a 10-day history of severe headache, photophobia, nausea, unsteadiness and slurring of speech. His CT head was normal. CSF white cell count was 151 (lymphocytes), protein 0.7, glucose 2.3 (serum 3.6). He was treated with IV acyclovir for two weeks with no clinical improvement. On examination he remained distressed by headache and photophobic with severe dysarthria, bidirec- tional nystagmus and ataxia. Blood tests were normal or negative including HIV, serology for syphilis, mycoplasma, lyme and brucella, ANA, ENA, dsDNA, ANCA, ACE, LGI1 and NMDA antibodies, anti-Hu, Ri and Yo. IGRA was positive. MRI brain scan was normal. Serial lumbar punctures showed a variable CSF white cell count, with a negative extended vir...


Friday 25 November 2022

Economic Burden of Reported Lyme Disease in High-Incidence Areas, United States, 2014-2016

Emerg Infect Dis. 2022 Jun;28(6):1170-1179. doi: 10.3201/eid2806.211335.ABSTRACTApproximately 476,000 cases of Lyme disease are diagnosed in the United States annually, yet comprehensive economic evaluations are lacking. In a prospective study among reported cases in Lyme disease-endemic states, we estimated the total patient cost and total societal cost of the disease. In addition, we evaluated disease and demographic factors associated with total societal cost. Participants had a mean patient cost of ≈$1,200 (median $240) and a mean societal cost of ≈$2,000 (median $700). Patients with confirmed disseminated disease or probable disease had approximately double the societal cost of those with confirmed localized disease. The annual, aggregate cost of diagnosed Lyme disease could be $3...


Friday 25 November 2022

Epidemiology of Lyme borreliosis based on outpatient claims data of all people with statutory health insurance, Germany, 2019

ConclusionsThese findings serve as a solid basis for regionally tailored population-based intervention programmes and can support modelling studies assessing the development of LB epidemiology under various climate change scenarios.PMID:35959689 | DOI:10.2807/1560-7917.ES.2022.27.32.2101193 (Source: Euro Surveill)

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Friday 25 November 2022

Economic Burden of Reported Lyme Disease in High-Incidence Areas, United States, 2014-2016

Emerg Infect Dis. 2022 Jun;28(6):1170-1179. doi: 10.3201/eid2806.211335.ABSTRACTApproximately 476,000 cases of Lyme disease are diagnosed in the United States annually, yet comprehensive economic evaluations are lacking. In a prospective study among reported cases in Lyme disease-endemic states, we estimated the total patient cost and total societal cost of the disease. In addition, we evaluated disease and demographic factors associated with total societal cost. Participants had a mean patient cost of ≈$1,200 (median $240) and a mean societal cost of ≈$2,000 (median $700). Patients with confirmed disseminated disease or probable disease had approximately double the societal cost of those with confirmed localized disease. The annual, aggregate cost of diagnosed Lyme disease could be $3...


Friday 25 November 2022

Comprehensive analyses of transcriptomes induced by Lyme spirochete infection to CNS model system

CONCLUSION: Our study suggested that TLR6, ANGPT1, LDLR, SREBF1, TNC, and ITGA may be candidate mammal biomarkers for LNB, and the TLR6/PI3K-Akt signaling pathway may play an important role in LNB pathogenesis.PMID:35964914 | DOI:10.1016/j.meegid.2022.105349 (Source: Infection, Genetics and Evolution)


Friday 25 November 2022

Economic Burden of Reported Lyme Disease in High-Incidence Areas, United States, 2014-2016

Emerg Infect Dis. 2022 Jun;28(6):1170-1179. doi: 10.3201/eid2806.211335.ABSTRACTApproximately 476,000 cases of Lyme disease are diagnosed in the United States annually, yet comprehensive economic evaluations are lacking. In a prospective study among reported cases in Lyme disease-endemic states, we estimated the total patient cost and total societal cost of the disease. In addition, we evaluated disease and demographic factors associated with total societal cost. Participants had a mean patient cost of ≈$1,200 (median $240) and a mean societal cost of ≈$2,000 (median $700). Patients with confirmed disseminated disease or probable disease had approximately double the societal cost of those with confirmed localized disease. The annual, aggregate cost of diagnosed Lyme disease could be $3...


Friday 25 November 2022

Bacterial infection-driven lymphomagenesis

Purpose of review The first convincing evidence for a causal relationship between bacterial infection and lymphomagenesis came from the link between gastric lymphoma and chronic Helicobacter pylori gastritis. This review will summarize the current epidemiological, clinical, and biological evidence of a causative role of bacteria in the development of malignant lymphomas, particularly, the extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue type. Recent findings Other microorganisms have been associated with specific extranodal lymphoma sites with variable and not always definitive, evidence, including Chlamydia psittaci, Borrelia burgdorferi, Campylobacter jejuni and, most recently, Coxiella Burnetii. According to most plausible models, lymphoma growth is a co...


Friday 25 November 2022

Economic Burden of Reported Lyme Disease in High-Incidence Areas, United States, 2014-2016

Emerg Infect Dis. 2022 Jun;28(6):1170-1179. doi: 10.3201/eid2806.211335.ABSTRACTApproximately 476,000 cases of Lyme disease are diagnosed in the United States annually, yet comprehensive economic evaluations are lacking. In a prospective study among reported cases in Lyme disease-endemic states, we estimated the total patient cost and total societal cost of the disease. In addition, we evaluated disease and demographic factors associated with total societal cost. Participants had a mean patient cost of ≈$1,200 (median $240) and a mean societal cost of ≈$2,000 (median $700). Patients with confirmed disseminated disease or probable disease had approximately double the societal cost of those with confirmed localized disease. The annual, aggregate cost of diagnosed Lyme disease could be $3...


Friday 25 November 2022

Erythema Multiforme: A Presentation of COVID-19 Pneumonia

We present the case of a 63-year-old female unvaccinated against COVID-19. She presented with fever, cough, shortness of breath, and rash. The symptoms were present for four days and appeared after contact with a confirmed symptomatic COVID-19-positive family member. The rash started first on the chest and then spread to the face and whole body including the palms and soles. It was erythematous and maculopapular and is associated with ulceration and swelling of the lips. In places, it was confluent and had a target-like appearance. On admission, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction (PCR) was negative. As she was septic with initial suspicion of tick-borne infections, she was started on doxycycline. Given her symptoms on presentation, th...


Friday 25 November 2022

Review of the clinical spectrum of typical and atypical Lyme neuroborreliosis in southwest England

Conclusions This is the largest UK review of neuroborreliosis. The presentation is usually typical, but atypical presentations vary and can be challenging. The majority of patients recover fully. amyrossrussell@gmail.com (Source: Journal of Neurology, Neurosurgery and Psychiatry)


Friday 25 November 2022

Florid Lymphoid Hyperplasia or Lymphoma-like Lesion of the Lower Genital Tract: A 35-Year Literature Review in View of the New WHO Classification

Florid lymphoid hyperplasias of the lower female genital tract, also known as pseudolymphoma or lymphoma-like lesions, are benign lesions displaying histologic features which mimic aggressive B-cell lymphomas. Initially described by Young and colleagues in 1985, fewer than 100 cases have been published, making this lesion rather uncommon and subject to misdiagnoses. However, given that this entity has now been included in the World Health Organization’s most recent classification, greater clarity would be beneficial for pathologists and physicians. Thus, our report aims to review these entities and provide all available data. We reviewed the available literature according to PRISMA guidelines. We found that lymphoma-like lesions, regardless of their localization, display numerous superfi...


Friday 25 November 2022

165 A creepy diagnosis

A 44-year-old-female presented with 3 weeks history of sacral anaesthesia, painful left leg paraesthesia and urinary retention requiring intermittent self-catheterisation. A week prior, she had headache, flu-like symptoms and dysuria and received oral antibiotics for E-Coli urinary infection with a negative vaginal swab. She was systemically well. On examination, there was mild left ankle dorsiflexion and plantar flexion weakness, brisk lower limb reflexes and altered sensation in left L5 and bilateral S1 dermatomes. MRI of her whole spine showed subtle signal change in the conus medullaris. CSF revealed 113 white blood cells (80% lymphocytes) with normal protein and glucose and negative oligoclonal bands. Her CT chest,abdomen and pelvis was unremarkable as were: autoimmune and vasculitis ...


Friday 25 November 2022

Identifying platelet-derived factors as amplifiers of B. burgdorferi-induced cytokine production

Clin Exp Immunol. 2022 Aug 24:uxac073. doi: 10.1093/cei/uxac073. Online ahead of print.ABSTRACTPrevious studies have shown that monocytes can be 'trained' or tolerized by certain stimuli to respond stronger or weaker to a secondary stimulation. Rewiring of glucose metabolism was found to be important in inducing this phenotype. As we previously found that Borrelia burgdorferi (B. burgdorferi), the causative agent of Lyme borreliosis (LB), alters glucose metabolism in monocytes, we hypothesized that this may also induce long-term changes in innate immune responses. We found that exposure to B. burgdorferi decreased cytokine production in response to the TLR4-ligand lipopolysaccharide (LPS). In addition, B. burgdorferi exposure decreased baseline levels of glycolysis, as assessed by lactate ...


Friday 25 November 2022

A Tick-borne Cause of Hyponatremia: SIADH Due to Lyme Meningitis

An 83-year-old woman was incidentally found to have hyponatremia (125 mmol/L) when undergoing inpatient colonoscopy because of unspecific gastrointestinal symptoms and weight loss; no pathology was found on endoscopy. Further biochemistry was in keeping with the syndrome of inappropriate antidiuretic hormone (SIADH) secretion (urinary sodium 66 mmol/L, urinary osmolality 321 mosmol/kg, low uric acid); adrenal and thyroid function as well as glucose were normal. The patient was remarkably fit for her age, she was a lifelong non-smoker and her only medication was candesartan for hypertension. (Source: The American Journal of Medicine)

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Friday 25 November 2022

Tick range expansion to higher elevations: does Borrelia burgdorferi sensu lato facilitate the colonisation of marginal habitats?

Parasites can alter host and vector phenotype and thereby affect ecological processes in natural populations. Laboratory studies have suggested that Borrelia burgdorferi sensu lato, the causative agent of human L... (Source: BMC Evolutionary Biology)


Friday 25 November 2022

Forthcoming Issues

Lyme Disease and the Expanded Spectrum of Blacklegged Tick-Borne Infections (Source: Infectious Diseases Clinics of North America)


Friday 25 November 2022

Early Disseminated Lyme Disease

Early disseminated Lyme disease can involve the peripheral or central nervous system, but with early diagnosis and treatment, prognosis for full recovery is excellent. The typical clinical presentations of neuroborreliosis are highlighted, and an approach to diagnosis and treatment is described. (Source: Infectious Diseases Clinics of North America)


Friday 25 November 2022

Knowing the entire story – a focus group study on patient experiences with chronic Lyme-associated symptoms (chronic Lyme disease)

Healthcare providers frequently struggle to provide effective care to patients with chronic Lyme-associated symptoms (chronic Lyme disease, CLD), potentially causing these patients to feel misunderstood or neg... (Source: BMC Family Practice)


Friday 25 November 2022

Nervous System Lyme Disease –Facts and Fallacies

This article will review the reasons for these misunderstandings and the arguments against them. (Source: Infectious Diseases Clinics of North America)


Friday 25 November 2022

Assessment of Knowledge, Attitudes, and Practices Toward Ticks and Tickborne Disease among Healthcare Professionals Working in Schools in New York and Maryland

J Sch Nurs. 2022 Jun 1:10598405221099484. doi: 10.1177/10598405221099484. Online ahead of print.ABSTRACTHealthcare Professionals Working in Schools (HPWS) are responsible for providing health services to students and play a role in providing education to prevent illnesses, including tickborne diseases (TBD). Providing TBD education to children has been shown to increase prevention behaviors and knowledge of TBD symptoms, but little is known regarding the current state of TBD awareness among HPWS. In spring 2019 we conducted a cross-sectional knowledge, attitudes, and practices (KAP) survey of HPWS in two states with a high incidence of Lyme disease (LD) to inform design of TBD prevention programs. The survey queried general knowledge of TBDs, school practices regarding TBDs, and availabili...


Friday 25 November 2022

Cardiac Manifestations of Lyme Disease

Lyme carditis is an uncommon manifestation of Lyme disease. Most cases present with heart block of varying degrees, but the spectrum of disease includes other transient arrhythmias and structural manifestations, such as myopericarditis or cardiomyopathy. Antibiotics hasten the resolution of Lyme carditis, and cardiac pacing can be an adjunctive therapy. Outcomes are generally good, but there are rare fatalities associated with Lyme carditis. The latter underscores the continued need for improved modes of prevention of Lyme disease and the importance of its early recognition and treatment. (Source: Infectious Diseases Clinics of North America)

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Friday 25 November 2022

Assessment of Knowledge, Attitudes, and Practices Toward Ticks and Tickborne Disease among Healthcare Professionals Working in Schools in New York and Maryland

J Sch Nurs. 2022 Jun 1:10598405221099484. doi: 10.1177/10598405221099484. Online ahead of print.ABSTRACTHealthcare Professionals Working in Schools (HPWS) are responsible for providing health services to students and play a role in providing education to prevent illnesses, including tickborne diseases (TBD). Providing TBD education to children has been shown to increase prevention behaviors and knowledge of TBD symptoms, but little is known regarding the current state of TBD awareness among HPWS. In spring 2019 we conducted a cross-sectional knowledge, attitudes, and practices (KAP) survey of HPWS in two states with a high incidence of Lyme disease (LD) to inform design of TBD prevention programs. The survey queried general knowledge of TBDs, school practices regarding TBDs, and availabili...


Friday 25 November 2022

Lyme Disease in Children

Lyme disease is now the most frequently reported vector-borne disease in the United States. The highest incidence is in children aged 5 to 9  years with a male predominance. The most common manifestation, erythema migrans, is sometimes not recognized, leading to risk of complications. Testing for Lyme disease should only be done if there is a consistent clinical syndrome with exposure in a Lyme-endemic area. Most forms of Lyme disease a re successfully treated with short courses of oral therapy. Prevention and management of tick bites is important. (Source: Infectious Diseases Clinics of North America)


Friday 25 November 2022

Assessment of Knowledge, Attitudes, and Practices Toward Ticks and Tickborne Disease among Healthcare Professionals Working in Schools in New York and Maryland

J Sch Nurs. 2022 Jun 1:10598405221099484. doi: 10.1177/10598405221099484. Online ahead of print.ABSTRACTHealthcare Professionals Working in Schools (HPWS) are responsible for providing health services to students and play a role in providing education to prevent illnesses, including tickborne diseases (TBD). Providing TBD education to children has been shown to increase prevention behaviors and knowledge of TBD symptoms, but little is known regarding the current state of TBD awareness among HPWS. In spring 2019 we conducted a cross-sectional knowledge, attitudes, and practices (KAP) survey of HPWS in two states with a high incidence of Lyme disease (LD) to inform design of TBD prevention programs. The survey queried general knowledge of TBDs, school practices regarding TBDs, and availabili...

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Friday 25 November 2022

Epidemiology of Lyme Disease

Lyme disease is the most common vector-borne illness in North America and Europe. The etiologic agent, Borrelia burgdorferi sensu lato, is transmitted to humans by certain species of Ixodes ticks, which are found widely in temperate regions of the Northern hemisphere. Clinical features are diverse but death is rare. The risk of human infection is determined by the distribution and abundance of vector ticks, ecologic factors influencing tick infection rates, and human behaviors that promote tick bite. Rates of infection are highest among children aged 5 to 15  years and adults aged more than 50 years. In the northeastern United States where disease is most common, exposure occurs primarily in areas immediately around the home. Knowledge of disease epidemiology is important for patient mana...


Friday 25 November 2022

Assessment of Knowledge, Attitudes, and Practices Toward Ticks and Tickborne Disease among Healthcare Professionals Working in Schools in New York and Maryland

J Sch Nurs. 2022 Jun 1:10598405221099484. doi: 10.1177/10598405221099484. Online ahead of print.ABSTRACTHealthcare Professionals Working in Schools (HPWS) are responsible for providing health services to students and play a role in providing education to prevent illnesses, including tickborne diseases (TBD). Providing TBD education to children has been shown to increase prevention behaviors and knowledge of TBD symptoms, but little is known regarding the current state of TBD awareness among HPWS. In spring 2019 we conducted a cross-sectional knowledge, attitudes, and practices (KAP) survey of HPWS in two states with a high incidence of Lyme disease (LD) to inform design of TBD prevention programs. The survey queried general knowledge of TBDs, school practices regarding TBDs, and availabili...


Friday 25 November 2022

Early Lyme Disease (Erythema Migrans) and Its Mimics (Southern Tick-Associated Rash Illness and Tick-Associated Rash Illness)

Erythema migrans, an expanding erythematous skin lesion that develops days to weeks following an Ixodes species tick bite, is the most common clinical manifestation of Lyme disease. Presentations in the United States differ somewhat from that in Europe, presumably because of the different etiologic agents. Diagnosis is based on the appearance of the skin lesion, rather than on laboratory testing. After treatment with an appropriate oral antibiotic for 10 to 14  days, the prognosis is excellent. Two conditions that cause a similar skin lesion following a tick bite, but are of unknown cause, are Southern tick-associated rash illness in the United States and tick-associated rash illness in Japan. (Source: Infectious Diseases Clinics of North America)


Friday 25 November 2022

Peptidylarginine Deiminase 2 Autoantibodies Are Linked to Less Severe Disease in Multiple Sclerosis and Post-treatment Lyme Disease

ConclusionPADI2 expression was observed in diverse regions and cells of the CNS, and anti-PAD2 autoantibodies were associated with less severe symptoms in subsets of patients with MS and PTLD. These data suggest that anti-PAD2 antibodies may attenuate inflammation in diseases of different etiologies, which are united by high PADI2 expression in the target tissue. (Source: Frontiers in Neurology)


Friday 25 November 2022

Lyme Arthritis

Arthritis is the most common late manifestation of Borrelia burgdorferi infection in the United States, usually beginning months after the tick bite. In most patients with Lyme arthritis (LA) today, arthritis is the presenting manifestation of the disease. Patients have swelling and pain in one or a few large joints, especially the knee. Serologic testing is the mainstay of diagnosis. Responses to antibiotic treatment are generally excellent, although a small percentage of patients have persistent, postinfectious synovitis after 2 to 3  months of oral and IV antibiotics, which respond to anti-inflammatory therapies. Herein we review the clinical presentation, diagnosis, and management of LA. (Source: Infectious Diseases Clinics of North America)


Friday 25 November 2022

Effectiveness of antibiotic treatment in children with Lyme neuroborreliosis - a retrospective study

Lyme neuroborreliosis (LNB) is a tick-borne infection caused by the spirochete Borrelia burgdorferi sensu lato complex with various neurological manifestations. The recommended treatment for LNB in Swedish childr... (Source: BMC Pediatrics)


Friday 25 November 2022

Diagnostic Testing for Lyme Disease

Standard 2-tier testing (STTT), incorporating a screening enzyme immunoassay (EIA) or an immunofluorescence assay (IFA) that reflexes to IgM and IgG immunoblots, has been the primary diagnostic test for Lyme disease since 1995. In 2019, the Food and Drug Administration approved a modified 2-tier test strategy using 2 EIAs: offering a faster, less expensive, and more sensitive assay compared with STTT. New technologies examine early immune responses to Borrelia burgdorferi have the potential to diagnose Lyme disease in the first weeks of infection when existing serologic testing is not recommended due to low sensitivity. (Source: Infectious Diseases Clinics of North America)

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Friday 25 November 2022

More than 1 in 7 people worldwide have had Lyme disease

Lyme disease is becoming increasingly common across the world, with warming temperatures one possible culprit for ticks spreading to new regions (Source: New Scientist - Health)

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Friday 25 November 2022

When to Think About Other Borreliae:

In North America, several hard tick-transmitted Borrelia species other than Borrelia burgdorferi cause human disease, including Borrelia miyamotoi, Borrelia mayonii, and possibly Borrelia bissettii. Due to overlapping clinical syndromes, nonspecific tickborne disease (TBD) testing strategies, and shared treatment approaches, infections with these lesser known Borrelia are likely under-reported. In this article, we describe the epidemiology, clinical manifestations, diagnosis, and treatment of these less common Borrelia pathogens. (Source: Infectious Diseases Clinics of North America)


Friday 25 November 2022

Occam vs Hickam

A 23-year-old man presented with new onset horizontal diplopia 5 months after a left orbital floor fracture. Examination revealed bilateral abduction deficits and disc swelling. Urgent MRI and MRI showed no significant abnormalities in the CNS. Lumbar puncture revealed a minimally elevated opening pressure and significant leukocytosis. Additional CSF testing revealed probable Lyme meningitis. The patient responded to a course of oral doxycycline, with rapid resolution of his diplopia, abduction deficits, and disc edema. (Source: Survey of Ophthalmology)


Friday 25 November 2022

The Role of the Infectious Disease Consultation in Lyme Disease

A consultation regarding Lyme disease can be challenging for the infectious disease physician when the referral question centers on the use of prolonged or empirical antibiotic treatment of Lyme disease and associated tick-borne infections. Patients who have been infected with Borrelia burgdorferi, and many who have been misdiagnosed, are confronted with a seemingly endless array of misinformation that is not in keeping with the current understanding of the clinical spectrum of Lyme disease and its response to evidence-based treatment. Preparing for these conversations with a good grasp of the public beliefs regarding Lyme disease and its treatment can be beneficial. (Source: Infectious Diseases Clinics of North America)


Friday 25 November 2022

News at a glance: Webb telescope dinged, U.S.-Russia research paused, and NASA ’s UFO study

Table of contents A version of this story appeared in Science, Vol 376, Issue 6599. Download PDF ASTRONOMY Star mapper provides Milky Way portrait he European Space Agency’s Gaia satellite has now mapped almost 2 billion of the Milky Way’s stars, logging their positions, speeds, temperatures, and other parameters—and allowing astronomers to chart the Galaxy’s structure and evolution. Last week, operators released the third major trove of data, including lists of 800,000 binary stars, 10 million variable stars, and, within the Solar System, 156,000 asteroids and rocky bodies. Launched in 2013, Gaia has already uncovered new nearby satellite galaxies, fast-moving stars escaping the Milky Way, and evidence of past ga...

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Friday 25 November 2022

Persistent Symptoms After Treatment of Lyme Disease

Most patients with Lyme disease will fully recover with recommended antibiotic therapy. However, some patients report persisting nonspecific symptoms after treatment, referred to as posttreatment Lyme disease symptoms (PTLDs) or syndrome (PTLDS), depending on the degree to which the individual ’s symptoms impact their quality of life. PTLDs occur in a portion of patients diagnosed with chronic Lyme disease (CLD), a controversial term describing different patient populations, diagnosed based on unvalidated tests and criteria. Practitioners should review the evidence for the Lyme disease diagnosis and not overlook unrelated conditions. Current evidence shows that prolonged antibiotic therapy provides little benefit and carries significant risk. Further research to elucidate the mechanisms ...


Friday 25 November 2022

Lesion Localization and Prognosis Using Electrodiagnostic Studies in Facial Diplegia: A Rare Variant of Guillain-Barre Syndrome

Conclusions Bilateral facial nerve palsy is an extremely rare condition with a varied etiology. Electrodiagnostic studies are useful in detecting the underlying pathophysiologic processes, prognosis, and central or peripheral lesion localization in patients with facial diplegia.PMID:35719795 | PMC:PMC9200109 | DOI:10.7759/cureus.25047 (Source: Herpes)


Friday 25 November 2022

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Tick-borne diseases are a growing public health concern across much of North America.1 Black-legged ticks, in particular, continue their range of expansion in the northeast and upper midwestern United States, bringing with them an impressive list of human pathogens. Dr Mead puts the consequences of this phenomenon into context in our first article, entitled, “Epidemiology of Lyme disease.” East of the Mississippi, the vector tick Ixodes scapularis, commonly called the deer tick, may transmit seven different pathogens. (Source: Infectious Diseases Clinics of North America)


Friday 25 November 2022

Lesion Localization and Prognosis Using Electrodiagnostic Studies in Facial Diplegia: A Rare Variant of Guillain-Barre Syndrome

Conclusions Bilateral facial nerve palsy is an extremely rare condition with a varied etiology. Electrodiagnostic studies are useful in detecting the underlying pathophysiologic processes, prognosis, and central or peripheral lesion localization in patients with facial diplegia.PMID:35719795 | PMC:PMC9200109 | DOI:10.7759/cureus.25047 (Source: Herpes)


Friday 25 November 2022

Lyme Disease and the Expanded Spectrum of Blacklegged Tick-Borne Infections

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA (Source: Infectious Diseases Clinics of North America)

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Friday 25 November 2022

Reversible high-grade atrioventricular block with septal myocardial edema in Lyme carditis

AbstractA  34-year-old road builder was admitted to the authors’ emergency department due to progressive dyspnoea that had been present for 6 days. The patient had a history of excessive smoking (60 cigarettes/day). The medical history was otherwise unremarkable. A transient rash had occurred during wo rk 2 weeks previously. The patient could not remember a bite. The electrocardiogram showed 2:1 atrioventricular (AV) block with narrow QRS complexes. D‑dimer and C‑reactive protein were slightly elevated; all other laboratory findings were within normal range. Echocardiography revealed normal findings. ELISA and western blot analysis confirmed acute Lyme disease. Cardiac magnetic resonance imaging (MRI) disclosed myocardial edema in the interventricular septum. Antibiotic treatm...


Friday 25 November 2022

Anaplasmosis-Induced Atrial Flutter Resolving With Antibiotic Therapy

We describe a case of a 56-year-old man with recent tick exposure who presented in atrial flutter with variable atrioventricular block after 3 days of fever, chills, and arthralgias. The patient was successfully treated and stably returned to sinus rhythm after initiation of antibiotics without cardioversion and was found to be positive for A. phagocytophilum but negative for Lyme disease. To our knowledge, this represents the first reported case of anaplasmosis-associated atrial flutter. As infections increase in incidence, clinicians in endemic areas should be aware of the potential manifestations and treatment considerations of tick-borne carditis. (Source: Infectious Diseases in Clinical Practice)


Friday 25 November 2022

Management and clinical outcomes of Lyme disease in acute care facilities in 2 endemic regions of Quebec, Canada: a multicentre retrospective cohort study

CMAJ Open. 2022 Jun 28;10(2):E570-E576. doi: 10.9778/cmajo.20210063. Print 2022 Apr-Jun.ABSTRACTBACKGROUND: Despite increases in cases of Lyme disease, little is known about the management and clinical course of the disease in Canada. We aimed to describe the management and clinical course of Lyme disease in patients treated in acute care facilities in Quebec and to assess adherence to the 2006 Infectious Diseases Society of America (IDSA) guideline.METHODS: This retrospective multicentre cohort study included pediatric and adult patients with serologically confirmed Lyme disease treated in acute care facilities (12 community hospitals and 2 tertiary care centres) of 2 endemic regions of Quebec (Estrie and Montérégie), from 2004 to 2017. We considered drug choice, prescribed dose and tre...

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Friday 25 November 2022

Immune evasion strategies of major tick-transmitted bacterial pathogens

Trends Microbiol. 2022 Aug 30:S0966-842X(22)00214-1. doi: 10.1016/j.tim.2022.08.002. Online ahead of print.ABSTRACTTick-transmitted bacterial pathogens thrive in enzootic infection cycles, colonizing disparate vertebrate and arthropod tissues, often establishing persistent infections. Therefore, the evolution of robust immune evasion strategies is central to their successful persistence or transmission between hosts. To survive in nature, these pathogens must counteract a broad range of microbicidal host responses that can be localized, tissue-specific, or systemic, including a mix of these responses at the host-vector interface. Herein, we review microbial immune evasion strategies focusing on Lyme disease spirochetes and rickettsial or tularemia agents as models for extracellular and int...


Friday 25 November 2022

CspZ FH-Binding Sites as Epitopes Promote Antibody-Mediated Lyme Borreliae Clearance

Infection and Immunity, Ahead of Print. (Source: Infection and Immunity)


Friday 25 November 2022

Rickettsial infections are an unlikely cause of peripheral facial palsy in Southern Jutland, Denmark

CONCLUSION: Rickettsiosis is unlikely as a common cause of facial palsy in Southern Jutland, Denmark.FUNDING: The study was supported financially by the Knud and Edith Eriksen Mindefond and the Region of Southern Denmark.TRIAL REGISTRATION: The study population and the control group were approved by the Regional Committees on Health Research Ethics for Southern Denmark (S-20170136 and S-20170049) and by the Danish Data Protection Agency (17/31901 and 18/28928). All participants provided informed consent before their enrollment in the study.PMID:36065885 (Source: Danish Medical Journal)


Friday 25 November 2022

Molecular survey on the presence of arthropod-borne bacteria and protozoans in roe deer (Capreolus capreolus) and ticks from Central Italy

Acta Trop. 2022 Jul 1:106586. doi: 10.1016/j.actatropica.2022.106586. Online ahead of print.ABSTRACTEnvironmental changes, due to climatic emergency and to anthropogenic activities severely impact on the epidemiology of vector borne diseases, mostly when transmitted by ticks. The data about the distribution of microorganisms responsible for them in roe deer (Capreolus capreolus) population living in Italy are scanty and completely lacking in Tuscany, so a molecular survey was carried out to estimate the prevalence of some zoonotic tick-borne pathogens in roe deer, and ticks removed from them, living in areas of Central Italy with high risk of arthropod exposure. Spleen samples from 72 roe deer were tested by PCR for Anaplasma phagocytophilum, Borrelia burgdorferi s.l., Francisella tularens...


Friday 25 November 2022

Genes, Vol. 13, Pages 1604: Large-Scale Sequencing of Borreliaceae for the Construction of Pan-Genomic-Based Diagnostics

Genes doi: 10.3390/genes13091604 Authors: Kayla M. Socarras Benjamin S. Haslund-Gourley Nicholas A. Cramer Mary Ann Comunale Richard T. Marconi Garth D. Ehrlich The acceleration of climate change has been associated with an alarming increase in the prevalence and geographic range of tick-borne diseases (TBD), many of which have severe and long-lasting effects—particularly when treatment is delayed principally due to inadequate diagnostics and lack of physician suspicion. Moreover, there is a paucity of treatment options for many TBDs that are complicated by diagnostic limitations for correctly identifying the offending pathogens. This review will focus on the biology, disease pathology, and detection methodologies used for the Borreliaceae family which incl...

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Friday 25 November 2022

Sciatic –Vagal Nerve Stimulation by Electroacupuncture Alleviates Inflammatory Arthritis in Lyme Disease-Susceptible C3H Mice

Lyme disease is caused by Borrelia burgdorferi, and the pathogenesis of the disease is complex with both bacterial and host factors contributing to inflammatory responses. Lyme disease affects different organs including joints and results in arthritis. Immune responses stimulated by B. burgdorferi through toll-like receptors cause infiltration of leukocytes, which produce inflammatory cytokines and facilitate spirochete clearance. However, arthritic manifestations and chronic fatigue syndrome-like symptoms persist long after completion of antibiotic treatment regimens in a significant number of patients. To counter the effects of inflammation, treatment by non-steroidal anti-inflammatory drugs, hydroxychloroquine, or synovectomy to eradicate inflammatory arthritis in the involved joint cou...


Friday 25 November 2022

Unilateral ptosis and mydriasis secondary to presumed Lyme neuroborreliosis

(Source: Journal of AAPOS)


Friday 25 November 2022

Late onset Parry-Romberg syndrome: Lyme disease as a possible cause?

Australas J Dermatol. 2022 Jul 18. doi: 10.1111/ajd.13894. Online ahead of print.NO ABSTRACTPMID:35849704 | DOI:10.1111/ajd.13894 (Source: The Australasian Journal of Dermatology)


Friday 25 November 2022

Maladie de Lyme chez un nouveau-n é, compliquée par une réaction de Jarisch–Herxheimer

CMAJ. 2022 Sep 12;194(35):E1218-E1220. doi: 10.1503/cmaj.220112-f.NO ABSTRACTPMID:36096504 | PMC:PMC9477248 | DOI:10.1503/cmaj.220112-f (Source: Canadian Medical Association Journal)


Friday 25 November 2022

Rural parents' experience in receiving care for their newborn with Lyme disease

CMAJ. 2022 Jul 18;194(27):E950. doi: 10.1503/cmaj.220945.NO ABSTRACTPMID:35851535 | PMC:PMC9299737 | DOI:10.1503/cmaj.220945 (Source: Canadian Medical Association Journal)

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Friday 25 November 2022

Exp érience des soins chez une nouveau-née atteinte de la maladie de Lyme, relatée par des parents en milieu rural

CMAJ. 2022 Sep 12;194(35):E1232. doi: 10.1503/cmaj.220945-f.NO ABSTRACTPMID:36096507 | PMC:PMC9477254 | DOI:10.1503/cmaj.220945-f (Source: Canadian Medical Association Journal)


Friday 25 November 2022

Rural parents' experience in receiving care for their newborn with Lyme disease

CMAJ. 2022 Jul 18;194(27):E950. doi: 10.1503/cmaj.220945.NO ABSTRACTPMID:35851535 | PMC:PMC9299737 | DOI:10.1503/cmaj.220945 (Source: cmaj)


Friday 25 November 2022

Maladie de Lyme chez un nouveau-n é, compliquée par une réaction de Jarisch–Herxheimer

CMAJ. 2022 Sep 12;194(35):E1218-E1220. doi: 10.1503/cmaj.220112-f.NO ABSTRACTPMID:36096504 | PMC:PMC9477248 | DOI:10.1503/cmaj.220112-f (Source: Canadian Medical Association Journal)


Friday 25 November 2022

Rural parents' experience in receiving care for their newborn with Lyme disease

CMAJ. 2022 Jul 18;194(27):E950. doi: 10.1503/cmaj.220945.NO ABSTRACTPMID:35851535 | PMC:PMC9299737 | DOI:10.1503/cmaj.220945 (Source: Canadian Medical Association Journal)


Friday 25 November 2022

Exp érience des soins chez une nouveau-née atteinte de la maladie de Lyme, relatée par des parents en milieu rural

CMAJ. 2022 Sep 12;194(35):E1232. doi: 10.1503/cmaj.220945-f.NO ABSTRACTPMID:36096507 | PMC:PMC9477254 | DOI:10.1503/cmaj.220945-f (Source: Canadian Medical Association Journal)

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Friday 25 November 2022

Rural parents' experience in receiving care for their newborn with Lyme disease

CMAJ. 2022 Jul 18;194(27):E950. doi: 10.1503/cmaj.220945.NO ABSTRACTPMID:35851535 | PMC:PMC9299737 | DOI:10.1503/cmaj.220945 (Source: cmaj)


Friday 25 November 2022

Maladie de Lyme chez un nouveau-n é, compliquée par une réaction de Jarisch–Herxheimer

CMAJ. 2022 Sep 12;194(35):E1218-E1220. doi: 10.1503/cmaj.220112-f.NO ABSTRACTPMID:36096504 | PMC:PMC9477248 | DOI:10.1503/cmaj.220112-f (Source: Canadian Medical Association Journal)


Friday 25 November 2022

Rural parents' experience in receiving care for their newborn with Lyme disease

CMAJ. 2022 Jul 18;194(27):E950. doi: 10.1503/cmaj.220945.NO ABSTRACTPMID:35851535 | PMC:PMC9299737 | DOI:10.1503/cmaj.220945 (Source: Canadian Medical Association Journal)


Friday 25 November 2022

Exp érience des soins chez une nouveau-née atteinte de la maladie de Lyme, relatée par des parents en milieu rural

CMAJ. 2022 Sep 12;194(35):E1232. doi: 10.1503/cmaj.220945-f.NO ABSTRACTPMID:36096507 | DOI:10.1503/cmaj.220945-f (Source: Canadian Medical Association Journal)


Friday 25 November 2022

Rural parents' experience in receiving care for their newborn with Lyme disease

CMAJ. 2022 Jul 18;194(27):E950. doi: 10.1503/cmaj.220945.NO ABSTRACTPMID:35851535 | DOI:10.1503/cmaj.220945 (Source: cmaj)


Friday 25 November 2022

Maladie de Lyme chez un nouveau-n é, compliquée par une réaction de Jarisch–Herxheimer

CMAJ. 2022 Sep 12;194(35):E1218-E1220. doi: 10.1503/cmaj.220112-f.NO ABSTRACTPMID:36096504 | DOI:10.1503/cmaj.220112-f (Source: Canadian Medical Association Journal)


Friday 25 November 2022

Rural parents' experience in receiving care for their newborn with Lyme disease

CMAJ. 2022 Jul 18;194(27):E950. doi: 10.1503/cmaj.220945.NO ABSTRACTPMID:35851535 | DOI:10.1503/cmaj.220945 (Source: cmaj)


Friday 25 November 2022

Exp érience des soins chez une nouveau-née atteinte de la maladie de Lyme, relatée par des parents en milieu rural

CMAJ. 2022 Sep 12;194(35):E1232. doi: 10.1503/cmaj.220945-f.NO ABSTRACTPMID:36096507 | DOI:10.1503/cmaj.220945-f (Source: Canadian Medical Association Journal)

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Friday 25 November 2022

Rural parents' experience in receiving care for their newborn with Lyme disease

CMAJ. 2022 Jul 18;194(27):E950. doi: 10.1503/cmaj.220945.NO ABSTRACTPMID:35851535 | DOI:10.1503/cmaj.220945 (Source: Canadian Medical Association Journal)


Friday 25 November 2022

Maladie de Lyme chez un nouveau-n é, compliquée par une réaction de Jarisch–Herxheimer

CMAJ. 2022 Sep 12;194(35):E1218-E1220. doi: 10.1503/cmaj.220112-f.NO ABSTRACTPMID:36096504 | DOI:10.1503/cmaj.220112-f (Source: Canadian Medical Association Journal)


Friday 25 November 2022

Rural parents' experience in receiving care for their newborn with Lyme disease

CMAJ. 2022 Jul 18;194(27):E950. doi: 10.1503/cmaj.220945.NO ABSTRACTPMID:35851535 | DOI:10.1503/cmaj.220945 (Source: cmaj)


Friday 25 November 2022

Exp érience des soins chez une nouveau-née atteinte de la maladie de Lyme, relatée par des parents en milieu rural

CMAJ. 2022 Sep 12;194(35):E1232. doi: 10.1503/cmaj.220945-f.NO ABSTRACTPMID:36096507 | DOI:10.1503/cmaj.220945-f (Source: cmaj)


Friday 25 November 2022

Infectious diseases and cognition: do we have to worry?

ConclusionsTaken together, the studies examined in the present review emphasize that numerous acute and chronic infectious diseases share mechanisms that, when added to specific risk factors frequently found in older persons, contribute to considerably increase the risk of cognitive outcomes such as cognitive decline and dementia. This review may help to appreciate the role that infectious diseases play in cognitive trajectories and thus promote further investigation on the topic. (Source: Neurological Sciences)


Friday 25 November 2022

Maladie de Lyme chez un nouveau-n é, compliquée par une réaction de Jarisch–Herxheimer

CMAJ. 2022 Sep 12;194(35):E1218-E1220. doi: 10.1503/cmaj.220112-f.NO ABSTRACTPMID:36096504 | DOI:10.1503/cmaj.220112-f (Source: cmaj)


Friday 25 November 2022

Infectious diseases and cognition: do we have to worry?

CONCLUSIONS: Taken together, the studies examined in the present review emphasize that numerous acute and chronic infectious diseases share mechanisms that, when added to specific risk factors frequently found in older persons, contribute to considerably increase the risk of cognitive outcomes such as cognitive decline and dementia. This review may help to appreciate the role that infectious diseases play in cognitive trajectories and thus promote further investigation on the topic.PMID:35867217 | DOI:10.1007/s10072-022-06280-9 (Source: Herpes)


Friday 25 November 2022

Exp érience des soins chez une nouveau-née atteinte de la maladie de Lyme, relatée par des parents en milieu rural

CMAJ. 2022 Sep 12;194(35):E1232. doi: 10.1503/cmaj.220945-f.NO ABSTRACTPMID:36096507 | DOI:10.1503/cmaj.220945-f (Source: Canadian Medical Association Journal)


Friday 25 November 2022

Taking an antibiotic after sex could help curb three common STDs

A new study has shown that taking a single dose of a widely used, cheap antibiotic within 3 days after condomless sex can help prevent chlamydia, syphilis, and gonorrhea, three sexually transmitted infections (STIs, also referred to as sexually transmitted diseases or STDs ) that have soared in the United States, Europe, and elsewhere over the past 2 decades. The study, mainly in men who have sex with men (MSM) in San Francisco and Seattle, was halted in May after an independent data monitoring board found that the strategy, known as doxycycline postexposure prophylaxis (doxyPEP), reduced the risk of chlamydia and gonorrhea by more than 60%—a result so convincing there was no need to continue the study. DoxyPEP also appeared to protect against syphilis, but too few cases occur...


Friday 25 November 2022

Maladie de Lyme chez un nouveau-n é, compliquée par une réaction de Jarisch–Herxheimer

CMAJ. 2022 Sep 12;194(35):E1218-E1220. doi: 10.1503/cmaj.220112-f.NO ABSTRACTPMID:36096504 | DOI:10.1503/cmaj.220112-f (Source: cmaj)


Friday 25 November 2022

Delivery and effectiveness of entomopathogenic fungi for mosquito and tick control: current knowledge and research challenges

Acta Trop. 2022 Jul 29:106627. doi: 10.1016/j.actatropica.2022.106627. Online ahead of print.ABSTRACTInsects, ticks, and mites represent a threat to animal health globally, mainly due to their role as vectors of pathogens. Among the most important diseases, those transmitted by mosquitoes (e.g., malaria and arboviral infections) and ticks (e.g., Lyme borreliosis, babesiosis, and viral haemorrhagic fever) have a huge impact on human health. The principal methods available for reducing the public health burden of most vector-borne diseases are vector-based intervention relying to insecticides and acaricides. However, the use of these products is challenged by the introduction of invasive species, the quick development of physiological insecticide and acaricide resistance, and their non-targe...


Friday 25 November 2022

Exp érience des soins chez une nouveau-née atteinte de la maladie de Lyme, relatée par des parents en milieu rural

CMAJ. 2022 Sep 12;194(35):E1232. doi: 10.1503/cmaj.220945-f.NO ABSTRACTPMID:36096507 | DOI:10.1503/cmaj.220945-f (Source: cmaj)


Friday 25 November 2022

Prediction model for juvenile idiopathic arthritis: challenges and opportunities

Acute and chronic musculoskeletal pain is a common reason for referral to the pediatric rheumatologist. (1,2,3) The differential diagnosis is extensive; patients may be diagnosed with inflammatory joint pain, includingjuvenile idiopathic arthritis (JIA), arthritis related to infection (e.g.: reactive arthritis – including rheumatic fever and post-strep, viral arthritis, Lyme disease) and other autoimmune and inflammatory disorders such as systemic lupus erythematosus; painful non-inflammatory MSK disorders include overuse injuries (e.g.: patellofemoral pain syndrome (PFPS)), osteochondroses (i.e.: Osgoo d-Schlatter disease), benign joint hypermobility syndromes, benign limb pain of childhood; orthopedic disorders (e.g.: Legg-Calvé-Perthes and osteochondritis dissecans) and chronic MSK p...


Friday 25 November 2022

Case report: Dueling etiologies: Longitudinally extensive spinal cord lesion mimicking spinal cord infarct with simultaneous positive Lyme serology and amphiphysin antibody

ConclusionWe describe an unusual steroid-responsive, longitudinally extensive spinal cord lesion with radiological features of spinal cord infarct and a simultaneous finding of intrathecal Lyme antibodies and serum amphiphysin antibodies. (Source: Frontiers in Neurology)


Friday 25 November 2022

Cell ‐Mediated Cytotoxicity in Lyme Arthritis

ConclusionsWe propose that CD8+ T cell-mediated cytotoxicity, CD4+ T cell help, autoantibodies to vascular antigens, and complement deposition, may each have a role in microvasculature damage in post-antibiotic LA.This article is protected by copyright. All rights reserved. (Source: Arthritis and Rheumatology)


Friday 25 November 2022

FtlA and FtlB Are Candidates for Inclusion in a Next-Generation Multiantigen Subunit Vaccine for Lyme Disease

Infection and Immunity, Ahead of Print. (Source: Infection and Immunity)


Friday 25 November 2022

Lyme Disease, Anaplasmosis, and Babesiosis, Atlantic Canada

Emerg Infect Dis. 2022 Jun;28(6):1292-1294. doi: 10.3201/eid2806.220443.ABSTRACTIn July 2021, a PCR-confirmed case of locally acquired Babesia microti infection was reported in Atlantic Canada. Clinical features were consistent with babesiosis and resolved after treatment. In a region where Lyme disease and anaplasmosis are endemic, the occurrence of babesiosis emphasizes the need to enhance surveillance of tickborne infections.PMID:35608954 | DOI:10.3201/eid2806.220443 (Source: Emerging Infectious Diseases)

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Friday 25 November 2022

No correlation between symptom duration and intrathecal production of IgM and/or IgG antibodies in Lyme neuroborreliosis – a retrospective cohort study in Denmark

Lyme borreliosis is a vector-borne disease caused by spirochaetes of the Borrelia burgdorferi (Bb) sensu lato complex [1]. Lyme borreliosis has various distinct symptom manifestations, and 10 –15% of European patients develop Lyme neuroborreliosis (LNB) [2]. (Source: Journal of Infection)

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Friday 25 November 2022

Lyme Disease, Anaplasmosis, and Babesiosis, Atlantic Canada

Emerg Infect Dis. 2022 Jun;28(6):1292-1294. doi: 10.3201/eid2806.220443.ABSTRACTIn July 2021, a PCR-confirmed case of locally acquired Babesia microti infection was reported in Atlantic Canada. Clinical features were consistent with babesiosis and resolved after treatment. In a region where Lyme disease and anaplasmosis are endemic, the occurrence of babesiosis emphasizes the need to enhance surveillance of tickborne infections.PMID:35608954 | DOI:10.3201/eid2806.220443 (Source: Emerging Infectious Diseases)


Friday 25 November 2022

A Multiplex PCR assay for a differential diagnostic of rickettsiosis, Lyme disease and scrub typhus

CONCLUSION: We successfully developed a Multiplex PCR assay for differential diagnosis of rickettsiosis, Lyme disease and scrub typhus that could be a rapid and easy option in clinical and epidemiological practice.PMID:36124484 | DOI:10.4103/0972-9062.337506 (Source: Journal of Vector Borne Diseases)


Friday 25 November 2022

Borrelia miyamotoi FbpA and FbpB Are Immunomodulatory Outer Surface Lipoproteins With Distinct Structures and Functions

Pathogens that traffic in the blood of their hosts must employ mechanisms to evade the host innate immune system, including the complement cascade. The Lyme disease spirochete, Borreliella burgdorferi, has evolved numerous outer membrane lipoproteins that interact directly with host proteins. Compared to Lyme disease-associated spirochetes, relatively little is known about how an emerging tick-borne spirochetal pathogen, Borrelia miyamotoi, utilizes surface lipoproteins to interact with a human host. B. burgdorferi expresses the multifunctional lipoprotein, BBK32, that inhibits the classical pathway of complement through interaction with the initiating protease C1r, and also interacts with fibronectin using a separate intrinsically disordered domain. B. miyamotoi encodes two separate bbk32...

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Friday 25 November 2022

Saponins from Panax notoginseng ameliorate steroid resistance in lupus nephritis through regulating lymphocyte-derived exosomes in mice

In this study, low-dose methylprednisolone (0.8 mg/kg/day, MP) was used to induce a steroid-resistant lupus nephritis (SR-LN) mouse model in weeks one to four, and a therapeutic steroid dosage (MP 12 mg/kg/day) or a combined PNS (PNS 100 mg/kg/day) treatment was administered from week five to eight. Lymphocyte-derived exosomes (Lyme-Exos) were isolated from the spleens of mice and injected into untreated homozygous LN mice for 14 days via the tail vein. At the end of the experiment, the efficacy and mechanism of action of different groups of Lyme-Exos on LN mice were observed. The results revealed that exogenously injected Lyme-Exos were effectively taken up by the kidney and affected the progression of kidney disease. Steroid-resistant lymphocyte-derived exosomes intervented with PNS ...


Friday 25 November 2022

A man with Erbs disease

A man, currently aged 72, developed a spastic paraparesis without sensory abnormalities progressing to wheel-chair dependence and late urinary incontinence over 14 years. Apart from a history of type 2 diabetes mellitus, he was otherwise well. Extensive blood and CSF investigations including screening for HIV, HTLV1, syphilis, and Lyme disease were normal or negative. There was no evidence of neuropathy or denervation on EMG. MRI showed mild non-specific white matter signal change in both cerebral hemi- spheres. A provisional diagnosis of primary lateral sclerosis (PLS) was revised with the finding of elevated Very Long Chain Fatty Acids (VLCFAs). Genetic testing revealed a novel missense variant c.1771C>G p. (Arg591Gly) in exon 7 of the ABCD1 gene. Mutation in ABCD1 transporter leads t...


Friday 25 November 2022

Identification of amino acid domains of Borrelia burgdorferi P66 that are surface exposed and important for localization, oligomerization, and porin function of the protein

In this study, we experimentally characterized specific domains of P66 with regard to structure and function. First, we aligned the amino acid sequences of P66 from Lyme disease-causing Borrelia and relapsing fever-causing Borrelia to identify conserved and unique domains between these disease-causing clades. Then, we examined whether specific domains of P66 are exposed on the surface of the bacteria by introducing c-Myc epitope tags into each domain of interest. The c-Myc epitope tag inserted C-terminally to E33 (highly conserved domain), to T187 (integrin binding region domain and a non-conserved domain), and to E334 (non-conserved domain) were all detected on the surface of Borrelia burgdorferi. The c-Myc epitope tag inserted C-terminally to E33 and D303 in conserved domains disrupted P...


Friday 25 November 2022

A < i > Borrelia burgdorferi < /i > outer surface protein C (OspC) genotyping method using Luminex technology

by Patrick Pearson, Olivia Skaltsis, Chu-Yuan Luo, Guang Xu, Zachary Oppler, Dustin Brisson, Stephen M. RichBorrelia burgdorferi is an important tickborne human pathogen comprising several strains based on nucleotide sequence of the outer surface protein C (ospC) gene. Detection and characterization of differentospC genotypes is vital for research onB.burgdorferi and the risk it poses to humans. Here we present a novel, multiplex assay based on Luminex xMAP technology for the detection ofB.burgdorferi ospC genotypes. The assay has five major steps: amplification of theospC gene, hydrolyzation of surplus primers and nucleotides, incorporation of biotinylated nucleotides into the template DNA, hybridization to Luminex microspheres, and detection of fluorescent signals corresponding to eachos...


Friday 25 November 2022

Underrepresentation of Dermatologic Conditions in POC

PHM Session: Dermatologic Disease Presentations, Skin Color, and Disparities in Medical Care Presenters: Deawodi Ladzekpo, MD, and Sonya Tang Girdwood, MD, PhD, Cincinnati Children’s Hospital, Ohio Drs. Ladzekpo and Tang Girdwood brought to light disparities in medical care that result from the underrepresentation of dermatologic conditions in patients of color (POC). The topic was introduced with a reference to Lyme disease, in particular the fact that many POC aren’t diagnosed until they have advanced disease compared to white patients. The question was then put forth: Do POC not have symptoms until they are in the later stages? Or rather, does the lack of awareness of the appearance of erythema migrans on the skin of color delay their diagnosis and treatment? The first half of the s...

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Friday 25 November 2022

Knowing the entire story - a focus group study on patient experiences with chronic Lyme-associated symptoms (chronic Lyme disease)

CONCLUSION: Central themes found in CLD patients' communication are 1. the experience of significant symptoms, 2. for which adequate relief is only rarely found from conventional medical practitioners, and 3. that are largely invisible to the outside world. Verbalizing these themes, patients use various repertoires for their shared experiences, such as a feeling of abandonment or not being heard by the medical system, feelings of loss with respect to their previous health, and the idea that they might have been better off had they been diagnosed sooner. Working with these repertoires will enable healthcare providers to establish a shared perspective with their CLD patients, thus engaging in more fruitful doctor-patient communication. We hypothesize that these findings are not unique to CLD...


Friday 25 November 2022

Lyme neuroborreliosis as a cause of sudden sensorineural hearing loss and facial palsy

We present a case of sudden sensorineural hearing loss and rapidly progressive facial palsy in a female patient in her 40s with no, apparently, notable past medical or surgical history. Investigations revealed a positive serology forB.  burgdoferi and the MRI allowed us to identify suggestive signs of Lyme meningitis with multiple cranial nerve involvement. After diagnosis, the patient was treated with intravenous ceftriaxone with a full recovery of sensorineural deafness and facial palsy. This case report highlights the importance of collecting a complete medical history in all cases of facial palsy and sudden hearing loss while presenting an infrequent clinical presentation of early disseminated Lyme disease with neuroborreliosis. (Source: Clinical Case Reports)


Friday 25 November 2022

Knowing the entire story - a focus group study on patient experiences with chronic Lyme-associated symptoms (chronic Lyme disease)

CONCLUSION: Central themes found in CLD patients' communication are 1. the experience of significant symptoms, 2. for which adequate relief is only rarely found from conventional medical practitioners, and 3. that are largely invisible to the outside world. Verbalizing these themes, patients use various repertoires for their shared experiences, such as a feeling of abandonment or not being heard by the medical system, feelings of loss with respect to their previous health, and the idea that they might have been better off had they been diagnosed sooner. Working with these repertoires will enable healthcare providers to establish a shared perspective with their CLD patients, thus engaging in more fruitful doctor-patient communication. We hypothesize that these findings are not unique to CLD...


Friday 25 November 2022

Persistent Borrelia burgdorferi < em > Sensu Lato < /em > Infection after Antibiotic Treatment: Systematic Overview and Appraisal of the Current Evidence from Experimental Animal Models

Clin Microbiol Rev. 2022 Oct 12:e0007422. doi: 10.1128/cmr.00074-22. Online ahead of print.ABSTRACTLyme borreliosis is caused by spirochetes belonging to the Borrelia burgdorferi sensu lato group, which are transmitted by Ixodes tick species living in the temperate climate zones of the Northern Hemisphere. The clinical manifestations of Lyme borreliosis are diverse and treated with oral or intravenous antibiotics. In some patients, long-lasting and debilitating symptoms can persist after the recommended antibiotic treatment. The etiology of such persisting symptoms is under debate, and one hypothesis entails persistent infection by a subset of spirochetes after antibiotic therapy. Here, we review and appraise the experimental evidence from in vivo animal studies on the persistence of B. bu...

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Friday 25 November 2022

Diversity of Borrelia burgdorferi sensu lato in ticks and small mammals from different habitats

Ixodid ticks are important vectors for zoonotic pathogens, with Ixodes ricinus being the most important in Europe. Rodents are hosts of immature life stages of I. ricinus ticks and are considered main reservoirs ... (Source: Parasites and Vectors)

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Friday 25 November 2022

Six versus 2 weeks treatment with doxycycline in European Lyme neuroborreliosis: a multicentre, non-inferiority, double-blinded, randomised and placebo-controlled trial

Conclusion Our results strongly indicate that there are no benefits of doxycycline treatment beyond 2 weeks in European LNB. Trial registration number 2015-001481-25. (Source: Journal of Neurology, Neurosurgery and Psychiatry)


Friday 25 November 2022

Occam versus hickam

A 23-year-old man presented with new onset horizontal diplopia 5 months after a left orbital floor fracture. Examination revealed bilateral abduction deficits and disc swelling. Urgent MRI and MRI showed no significant abnormalities in the CNS. Lumbar puncture revealed a minimally elevated opening pressure and significant leukocytosis. Additional CSF testing revealed probable Lyme meningitis. The patient responded to a course of oral doxycycline, with rapid resolution of his diplopia, abduction deficits, and disc edema. (Source: Survey of Ophthalmology)


Friday 25 November 2022

Diving into the complexity of the spirochetal endoflagellum

Trends Microbiol. 2022 Oct 13:S0966-842X(22)00256-6. doi: 10.1016/j.tim.2022.09.010. Online ahead of print.ABSTRACTSpirochaetes, a phylum that includes medically important pathogens such as the causative agents of Lyme disease, syphilis, and leptospirosis, are in many ways highly unique bacteria. Their cell morphology, subcellular organization, and metabolism reveal atypical features. Spirochetal motility is also singular, dependent on the presence of periplasmic flagella or endoflagella, inserted subterminally at cell poles and not penetrating the outer membrane and elongating outside the cell as in enterobacteria. In this review we present a comprehensive comparative genomics analysis of endoflagellar systems in spirochetes, highlighting recent findings on the flagellar basal body and fi...


Friday 25 November 2022

Utility of Whole Blood Real-Time PCR Testing for the Diagnosis of Early Lyme Disease

CONCLUSIONS: When used concurrently with serologic testing, WB-RTPCR testing increases diagnostic sensitivity in cases of ELD.PMID:35723600 | DOI:10.1093/ajcp/aqac068 (Source: American Journal of Clinical Pathology)


Friday 25 November 2022

CME: Neuroborreliosis

Praxis (Bern 1994). 2022;111(14):779-787. doi: 10.1024/1661-8157/a003939.ABSTRACTCME: Neuroborreliosis Abstract. Lyme disease is the most common infectious disease transmitted by ticks throughout Europe. Bacteria of the Borrelia burgdorferi complex are transmitted via tick bites to humans. The typical initial presentation is a localized infection of the skin (Erythema migrans). If the patient is not treated with antibiotics, a disseminated infection might occur, presenting as neurological Lyme disease, Lyme carditis, Lyme arthritis or Acrodermatitis chronica atrophicans. A neuroborreliosis occurs in 3-15% of the cases. It may present as polyradiculitis, meningitis or - in rare cases - as encephalomyelitis. The antimicrobial therapy of neuroborreliosis is doxycyclin, ceftriaxone or penicill...


Friday 25 November 2022

Range Expansion of Ixodes scapularis and Borrelia burgdorferi in Ontario, Canada, from 2017 to 2019

Vector-Borne and Zoonotic Diseases, Ahead of Print. (Source: Vector-Borne and Zoonotic Diseases)

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Friday 25 November 2022

Testing Raman spectroscopy as a diagnostic approach for Lyme disease patients

Lyme disease (LD), the leading tick-borne disease in the Northern hemisphere, is caused by spirochetes of several genospecies of the Borreliella burgdorferi sensu lato complex. LD is a multi-systemic and highly debilitating illness that is notoriously challenging to diagnose. The main drawbacks of the two-tiered serology, the only approved diagnostic test in the United States, include poor sensitivity, background seropositivity, and cross-reactivity. Recently, Raman spectroscopy (RS) was examined for its LD diagnostic utility by our earlier proof-of-concept study. The previous investigation analyzed the blood from mice that were infected with 297 and B31 strains of Borreliella burgdorferi sensu stricto (s.s.). The selected strains represented two out of the three major clades of B. burgdor...


Friday 25 November 2022

Regional seropositivity for Borrelia burgdorferi and associated risk factors: findings from the Rhineland Study, Germany

Lyme borreliosis is the most prevalent vector-borne disease in Europe, and numbers might increase due to climate change. However, borreliosis is not notifiable in North Rhine-Westphalia (NRW), Germany. Hence, ... (Source: Parasites and Vectors)


Friday 25 November 2022

Lyme Carditis Presenting With Complete Heart Block and Wide Complex Escape Rhythm

Tex Heart Inst J. 2022 Sep 1;49(5):e207515. doi: 10.14503/THIJ-20-7515.ABSTRACTA 19-year-old woman with newly diagnosed Lyme disease presented with complete heart block and an accompanying escape rhythm with a right bundle branch block morphology. With antibiotics, her dysrhythmia resolved completely within 24 hours of presentation. This case highlights an unusual electrocardiographic manifestation of Lyme carditis.PMID:36315846 | DOI:10.14503/THIJ-20-7515 (Source: Texas Heart Institute Journal)


Friday 25 November 2022

Seroprevalence of Borrelia IgG antibodies among individuals from Eastern Slovakia

CONCLUSION: The study reveals that IgG-seropositivity for Borrelia burgdorferi in Eastern Slovakia is predominant in men and occurs mainly in rural areas. The findings also suggest that exposure to Borrelia burgdorferi (with subsequent antibody response in serum) does occur, mostly without giving rise to clinical Lyme borreliosis.PMID:35841220 | DOI:10.21101/cejph.a6808 (Source: Central European Journal of Public Health)


Friday 25 November 2022

Highlighting Infranodal Block in Lyme Carditis

Tex Heart Inst J. 2022 Sep 1;49(5):e217777. doi: 10.14503/THIJ-21-7777.NO ABSTRACTPMID:36315845 | DOI:10.14503/THIJ-21-7777 (Source: Texas Heart Institute Journal)

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Friday 25 November 2022

Lyme disease in a neonate complicated by the Jarisch-Herxheimer reaction

CMAJ. 2022 Jul 18;194(27):E939-E941. doi: 10.1503/cmaj.220112.NO ABSTRACTPMID:35851530 | PMC:PMC9299745 | DOI:10.1503/cmaj.220112 (Source: cmaj)


Friday 25 November 2022

Lyme Carditis Presenting With Complete Heart Block and Wide Complex Escape Rhythm

Tex Heart Inst J. 2022 Sep 1;49(5):e207515. doi: 10.14503/THIJ-20-7515.ABSTRACTA 19-year-old woman with newly diagnosed Lyme disease presented with complete heart block and an accompanying escape rhythm with a right bundle branch block morphology. With antibiotics, her dysrhythmia resolved completely within 24 hours of presentation. This case highlights an unusual electrocardiographic manifestation of Lyme carditis.PMID:36315846 | DOI:10.14503/THIJ-20-7515 (Source: Texas Heart Institute Journal)


Friday 25 November 2022

Lyme disease in a neonate complicated by the Jarisch-Herxheimer reaction

CMAJ. 2022 Jul 18;194(27):E939-E941. doi: 10.1503/cmaj.220112.NO ABSTRACTPMID:35851530 | PMC:PMC9299745 | DOI:10.1503/cmaj.220112 (Source: cmaj)


Friday 25 November 2022

Highlighting Infranodal Block in Lyme Carditis

Tex Heart Inst J. 2022 Sep 1;49(5):e217777. doi: 10.14503/THIJ-21-7777.NO ABSTRACTPMID:36315845 | DOI:10.14503/THIJ-21-7777 (Source: Texas Heart Institute Journal)


Friday 25 November 2022

Lyme disease in a neonate complicated by the Jarisch-Herxheimer reaction

CMAJ. 2022 Jul 18;194(27):E939-E941. doi: 10.1503/cmaj.220112.NO ABSTRACTPMID:35851530 | PMC:PMC9299745 | DOI:10.1503/cmaj.220112 (Source: Canadian Medical Association Journal)


Friday 25 November 2022

Lyme Carditis Presenting With Complete Heart Block and Wide Complex Escape Rhythm

Tex Heart Inst J. 2022 Sep 1;49(5):e207515. doi: 10.14503/THIJ-20-7515.ABSTRACTA 19-year-old woman with newly diagnosed Lyme disease presented with complete heart block and an accompanying escape rhythm with a right bundle branch block morphology. With antibiotics, her dysrhythmia resolved completely within 24 hours of presentation. This case highlights an unusual electrocardiographic manifestation of Lyme carditis.PMID:36315846 | DOI:10.14503/THIJ-20-7515 (Source: Texas Heart Institute Journal)


Friday 25 November 2022

Lyme disease in a neonate complicated by the Jarisch-Herxheimer reaction

CMAJ. 2022 Jul 18;194(27):E939-E941. doi: 10.1503/cmaj.220112.NO ABSTRACTPMID:35851530 | DOI:10.1503/cmaj.220112 (Source: Canadian Medical Association Journal)


Friday 25 November 2022

Highlighting Infranodal Block in Lyme Carditis

Tex Heart Inst J. 2022 Sep 1;49(5):e217777. doi: 10.14503/THIJ-21-7777.NO ABSTRACTPMID:36315845 | DOI:10.14503/THIJ-21-7777 (Source: Texas Heart Institute Journal)


Friday 25 November 2022

Lyme disease in a neonate complicated by the Jarisch-Herxheimer reaction

CMAJ. 2022 Jul 18;194(27):E939-E941. doi: 10.1503/cmaj.220112.NO ABSTRACTPMID:35851530 | DOI:10.1503/cmaj.220112 (Source: cmaj)


Friday 25 November 2022

Lyme Carditis Presenting With Complete Heart Block and Wide Complex Escape Rhythm

Tex Heart Inst J. 2022 Sep 1;49(5):e207515. doi: 10.14503/THIJ-20-7515.ABSTRACTA 19-year-old woman with newly diagnosed Lyme disease presented with complete heart block and an accompanying escape rhythm with a right bundle branch block morphology. With antibiotics, her dysrhythmia resolved completely within 24 hours of presentation. This case highlights an unusual electrocardiographic manifestation of Lyme carditis.PMID:36315846 | DOI:10.14503/THIJ-20-7515 (Source: Texas Heart Institute Journal)


Friday 25 November 2022

Redox Imbalance and Its Metabolic Consequences in Tick-Borne Diseases

One of the growing global health problems are vector-borne diseases, including tick-borne diseases. The most common tick-borne diseases include Lyme disease, tick-borne encephalitis, human granulocytic anaplasmosis, and babesiosis. Taking into account the metabolic effects in the patient’s body, tick-borne diseases are a significant problem from an epidemiological and clinical point of view. Inflammation and oxidative stress are key elements in the pathogenesis of infectious diseases, including tick-borne diseases. In consequence, this leads to oxidative modifications of the structure and function of phospholipids and proteins and results in qualitative and quantitative changes at the level of lipid mediators arising in both reactive oxygen species (ROS) and ROS enzyme–dependent reacti...


Friday 25 November 2022

Highlighting Infranodal Block in Lyme Carditis

Tex Heart Inst J. 2022 Sep 1;49(5):e217777. doi: 10.14503/THIJ-21-7777.NO ABSTRACTPMID:36315845 | DOI:10.14503/THIJ-21-7777 (Source: Texas Heart Institute Journal)

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Friday 25 November 2022

Climate Change and Cascading Risks from Infectious Disease

AbstractClimate change is adversely affecting the burden of infectious disease throughout the world, which is a health security threat. Climate-sensitive infectious disease includes vector-borne diseases such as malaria, whose transmission potential is expected to increase because of enhanced climatic suitability for the mosquito vector in Asia, sub-Saharan Africa, and South America. Climatic suitability for the mosquitoes that can carry dengue, Zika, and chikungunya is also likely to increase, facilitating further increases in the geographic range and longer transmission seasons, and raising concern for expansion of these diseases into temperate zones, particularly under higher greenhouse gas emission scenarios. Early spring temperatures in 2018 seem to have contributed to the early onset...


Friday 25 November 2022

Lyme Carditis Presenting With Complete Heart Block and Wide Complex Escape Rhythm

Tex Heart Inst J. 2022 Sep 1;49(5):e207515. doi: 10.14503/THIJ-20-7515.ABSTRACTA 19-year-old woman with newly diagnosed Lyme disease presented with complete heart block and an accompanying escape rhythm with a right bundle branch block morphology. With antibiotics, her dysrhythmia resolved completely within 24 hours of presentation. This case highlights an unusual electrocardiographic manifestation of Lyme carditis.PMID:36315846 | DOI:10.14503/THIJ-20-7515 (Source: Texas Heart Institute Journal)


Friday 25 November 2022

Borrelial lymphocytoma

Wien Klin Wochenschr. 2022 Aug 9. doi: 10.1007/s00508-022-02064-5. Online ahead of print.ABSTRACTBorrelial lymphocytoma is a rare cutaneous manifestation of early localized European Lyme borreliosis. It manifests as a nodule or plaque with a diameter of up to a few centimeters. The lesion is, as a rule, solitary. It is more common in children than in adults and, in contrast to erythema migrans and acrodermatitis chronica atrophicans, has male predominance. A tick bite has been reported in approximately one half of patients; the tick bite is usually at the site or in the vicinity of the later borrelial lymphocytoma. The predilection site for the development of lesions is the breast in adults and the ear lobe in children. Borrelial lymphocytoma is frequently associated with erythema migrans,...


Friday 25 November 2022

Tick feeding modulates the human skin immune landscape to facilitate tick-borne pathogen transmission

During cutaneous tick attachment, the feeding cavity becomes a site of transmission for tick salivary compounds and tick-borne pathogens. However, the immunological consequences of tick feeding for human skin remain unclear. Here, we assessed human skin and blood samples upon tick bite and developed a human skin explant model mimicking Ixodes ricinus bites and tick-borne pathogen infection. Following tick attachment, we observed rapidly occurring patterns of immunomodulation, including increases in neutrophils and cutaneous B and T cells. T cells upregulated tissue residency markers, while lymphocytic cytokine production was impaired. In early stages of Borrelia burgdorferi model infections, we detected strain-specific immune responses and close spatial relationships between macrophages an...


Friday 25 November 2022

Lyme Disease, Anaplasmosis, and Babesiosis, Atlantic Canada

Emerg Infect Dis. 2022 Jun;28(6):1292-1294. doi: 10.3201/eid2806.220443.ABSTRACTIn July 2021, a PCR-confirmed case of locally acquired Babesia microti infection was reported in Atlantic Canada. Clinical features were consistent with babesiosis and resolved after treatment. In a region where Lyme disease and anaplasmosis are endemic, the occurrence of babesiosis emphasizes the need to enhance surveillance of tickborne infections.PMID:35608954 | DOI:10.3201/eid2806.220443 (Source: Emerging Infectious Diseases)


Friday 25 November 2022

Long-lost ‘sea dragon’ replicas unearthed in museum collections

This report will have people taking a closer look at some of their casts.” Decades before the word “dinosaur” entered the scientific lexicon, ichthyosaurs were the rock stars of the nascent paleontology field. The first complete ichthyosaur skeleton hailed from Lyme Regis, a seaside town along southern England’s iconic Jurassic Coast. Eroding out of the area’s wave-battered limestone cliffs are the inhabitants of a tropical sea from 200 million years ago, including squidlike ammonites, pterosaurs, and a slew of marine reptiles, including ichthyosaurs and long-necked plesiosaurs. Fossil hunters have flocked to these crumbling cliffs for centuries, thanks in part to the prodigious collecting of pioneering paleontologist Mary Anning in the early 1800s. The daughter of an a...


Friday 25 November 2022

A wolf in sheeps clothing

A 28 year-old Caucasian woman was found to have reduced visual acuity during routine optician checks and was referred to ophthalmology and then neurology. Examination revealed acuities of 6/12 in both eyes, pale optic discs and reduced colour perception. MRI brain did not show any lesions. Routine bloods were normal as were serum ACE, B1, B12, folate, HIV, syphilis, Lyme serology, AQP4-IgG and MOG-IgG. Leber’s and AD optic atrophy screens were negative. CSF protein was 0.41, WBC 7 (100% lymphocytes), elevated IgG Index 1.4 (normal<0.8),OCBs in serum and CSF with a single additional band raising the possibility of inflammatory optic neuritis. There was apparent stabilisation on empiric steroids which was then converted to steroid sparing immunosuppressants. However, as vision decli...


Friday 25 November 2022

The environment, the tick, and the pathogen – It is an ensemble

Ixodes scapularis is one of the predominant vectors of Borrelia burgdorferi, the agent of Lyme disease in the USA. The geographic distribution of I. scapularis, endemic to the northeastern and northcentral USA, is expanding as far south as Georgia and Texas, and northwards into Canada and poses an impending public health problem. The prevalence and spread of tick-borne diseases are influenced by the interplay of multiple factors including microbiological, ecological, and environmental. Molecular studies have focused on interactions between the tick-host and pathogen/s that determine the success of pathogen acquisition by the tick and transmission to the mammalian host. In this review we draw attention to additional critical environmental factors that impact tick biology and tick-pathogen i...


Friday 25 November 2022

Knowing the entire story - a focus group study on patient experiences with chronic Lyme-associated symptoms (chronic Lyme disease)

CONCLUSION: Central themes found in CLD patients' communication are 1. the experience of significant symptoms, 2. for which adequate relief is only rarely found from conventional medical practitioners, and 3. that are largely invisible to the outside world. Verbalizing these themes, patients use various repertoires for their shared experiences, such as a feeling of abandonment or not being heard by the medical system, feelings of loss with respect to their previous health, and the idea that they might have been better off had they been diagnosed sooner. Working with these repertoires will enable healthcare providers to establish a shared perspective with their CLD patients, thus engaging in more fruitful doctor-patient communication. We hypothesize that these findings are not unique to CLD...

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Friday 25 November 2022

Enhancement of cranial nerves in Lyme neuroborreliosis: incidence and correlation with clinical symptoms and prognosis

ConclusionsMRI cranial nerve enhancement is common in LNB patients, but it can be clinically occult. Facial and oculomotor nerves are most often affected. Enhancement of the facial nerve distal internal auditory canal and parotid segments correlate with degree of facial palsy. (Source: Neuroradiology)

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Friday 25 November 2022

Brain damage markers neuron-specific enolase (NSE) and S100B in serum in children with Lyme neuroborreliosis —detection and evaluation as prognostic biomarkers for clinical outcome

AbstractLyme borreliosis (LB) is the most common tick-borne infection in Europe, with Lyme neuroborreliosis (LNB) its second most frequent clinical manifestation. Prognostic factors for clinical outcomes in LNB have not been identified. Elevated serum levels of the brain damage markers neuron-specific enolase (NSE) and S100 calcium-binding protein B (S100B) have been associated with poor clinical outcomes in other disorders of the central nervous system. The aim of this study is to assess NSE and S100B in serum as prognostic biomarkers for clinical outcomes in paediatric LNB patients. Children evaluated for LNB (n = 121) in Sweden were prospectively included during 2010–2014, serum samples were collected on admission, and all children underwent a 2-month follow-up. Patients with pleo...


Friday 25 November 2022

GSE216261 Borrelia burgdorferi gene expression from inside its tick vector during a bloodmeal

Contributors : Anne L Sapiro ; Beth Hayes ; Seemay ChouSeries Type : Expression profiling by high throughput sequencingOrganism : Borreliella burgdorferiBorrelia burgdorferi, the causative agent of Lyme disease, is transmitted to vertebrate hosts by Ixodes ticks. As it moves from tick to host, B. burgdorferi must adapt to survive in a vastly different environment. During the tick bloodmeal, which lasts several days, B. burgdorferi is primed for mammalian infection, growing increasingly virulent as it senses cues from its surroundings in the tick. This conditioning is dependent on key transcriptional regulators; however, the downstream transcriptional changes occurring inside of the tick that promote B. burgdorferi transmission and infection are poorly understood due to technical difficulti...


Friday 25 November 2022

Climate change and child health: A nationwide survey among paediatricians in Germany

CONCLUSION: The results of the study illustrate that the topic "climate change and health" has a high relevance for paediatricians and that information measures for parents are considered to be effective. Although paediatricians are concerned with the topic, there is an implementation deficit. Support is needed in the form of intensifying awareness raising projects and educational modules for paediatricians to move from knowledge to action.PMID:35710526 | DOI:10.1016/j.zefq.2022.03.007 (Source: Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen)


Friday 25 November 2022

Systematic Review and Meta-analysis of Lyme Disease Data and Seropositivity for Borrelia burgdorferi, China, 2005 ‒2020

J. Stark et al. (Source: Emerging Infectious Diseases Journal)


Friday 25 November 2022

Pfizer buys stake in Lyme vaccine developer Valneva

(Source: Chemical and Engineering News)


Friday 25 November 2022

Identification of novel conserved Ixodes vaccine candidates; a promising role for non-secreted salivary gland proteins

Vaccine. 2022 Nov 8:S0264-410X(22)01292-0. doi: 10.1016/j.vaccine.2022.10.032. Online ahead of print.ABSTRACTIxodes ricinus and Ixodes scapularis are the main vectors for the causative agents of Lyme borreliosis and a wide range of other pathogens. Repeated tick-bites are known to lead to tick rejection; a phenomenon designated as tick immunity. Tick immunity is mainly directed against tick salivary gland proteins (TSGPs) and has been shown to partially protect against experimental Lyme borreliosis. TSGPs recognized by antibodies from tick immune animals could therefore be interesting candidates for an anti-tick vaccine, which might also block pathogen transmission. To identify conserved Ixodes TSGPs that could serve as a universal anti-tick vaccine in both Europe and the US, a Yeast Surfa...


Friday 25 November 2022

Hematogenous dissemination of pathogenic and non-pathogenic Leptospira in a short-term murine model of infection

Leptospirosis is an emerging zoonosis caused by pathogenic Leptospira spp. Because rodents are natural hosts of Leptospira, rodent models of pathogenesis have been limited, but are valuable to understand infection in reservoir animals even in the absence of disease. Mouse models of infection provide advantages due to genetic tractability, so developing murine models of Leptospira infection is crucial for further understanding the biology of this organism. Previously our laboratory developed a short-term murine model of Borrelia burgdorferi hematogenous dissemination to investigate the role of adhesion proteins on bacterial survival and dissemination within a host. Here we adapt this model to Leptospira. C3H/HeJ mice are anesthetized, inoculated intravenously, and then bacteria are allowed ...


Friday 25 November 2022

IJERPH, Vol. 19, Pages 14893: Prevalence of Lyme Carditis in Patients with Atrioventricular Blocks

International Journal of Environmental Research and Public Health doi: 10.3390/ijerph192214893 Authors: Krzysztof A. Kaczmarek Katarzyna Szwabe Irmina Urbanek Pawel Ptaszynski Aleksander Strzelecki Jerzy K. Wranicz Iwona Cygankiewicz Infections with Borrelia may cause cardiac conduction system abnormalities, including atrioventricular blocks (AVBs). Therefore, we aimed to identify patients in whom Lyme carditis (LC) could be considered as the initial diagnosis among consecutive subjects who were referred for implantation of a permanent pacemaker due to symptomatic AVBs. To date, such a systematic evaluation has not been reported yet. Validation of the Suspicious Index for Lyme Carditis (SILC) in our study population was considered as an additional goal. We investigated...

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Friday 25 November 2022

Lyme disease in a neonate complicated by the Jarisch-Herxheimer reaction

CMAJ. 2022 Jul 18;194(27):E939-E941. doi: 10.1503/cmaj.220112.NO ABSTRACTPMID:35851530 | PMC:PMC9299745 | DOI:10.1503/cmaj.220112 (Source: Canadian Medical Association Journal)

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Friday 25 November 2022

11 The epidemiology of infections as a risk factor for psychiatric illness

Michael Eriksen Benros, M.D., Ph.D. is professor and Head of Research at Mental Health Centre Copenhagen, Copenhagen University Hospital, Denmark. He received a two year grant from GLA for his study: Nationwide Cohort Studies Examining Psychiatric Disorders and Suicidal Behavior after Lyme disease. Abstract The immune system is linked to an increasing number of medical diseases, including lately also severe mental disorders. Utilizing the nationwide registers and biobanks in Denmark we have consistently displayed that infections and autoimmune diseases increases the risk of developing severe mental disorders in a dose-response relationship, where the risk of severe mental disorders particularly increases with the amount of infections exposed to. It is a broad range of infections and autoi...


Friday 25 November 2022

Lyme disease in a neonate complicated by the Jarisch-Herxheimer reaction

CMAJ. 2022 Jul 18;194(27):E939-E941. doi: 10.1503/cmaj.220112.NO ABSTRACTPMID:35851530 | DOI:10.1503/cmaj.220112 (Source: Canadian Medical Association Journal)


Friday 25 November 2022

Rurality, Socioeconomic Status, and Residence in Environmental Risk Areas Associated with Increased Lyme Disease Incidence in Ontario, Canada: A Case-Control Study

Vector-Borne and Zoonotic Diseases, Ahead of Print. (Source: Vector-Borne and Zoonotic Diseases)


Friday 25 November 2022

The challenge of Morgellons disease: a patient with clinico-pathologic correlation

Morgellons disease is a rare condition characterized by patient reporting multicolored fibers and other non-organic or organic particles embedded in and protruding from diffuse skin ulcerations. Although the scientific community is prone to believe that Morgellons disease is a psychiatric disorder, an infectious pathogenesis associated with Borrelia burgdorferi in the setting of Lyme disease has also been proposed. The histopathology is usually considered as non-specific. To illustrate this condition, we present the case of an adult woman with significant ulcerative skin lesions and cicatricial changes on the face, trunk, and arms. (Source: Clinics in Dermatology)

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Friday 25 November 2022

Is Vestibular Neuropathy Rather a Neuritis?

Conclusion In this cohort, there was a large number of VN patients with infectious signs; several patients tested positive for HSV and LD. Therefore we recommend testing VN patients not only for HSV but also for LD and other neurotropic viruses. This approach enables to complement the standard VN treatment with a specific treatment.PMID:36381739 | PMC:PMC9635860 | DOI:10.7759/cureus.29959 (Source: Herpes)


Friday 25 November 2022

Lyme Disease, Anaplasmosis, and Babesiosis, Atlantic Canada

Emerg Infect Dis. 2022 Jun;28(6):1292-1294. doi: 10.3201/eid2806.220443.ABSTRACTIn July 2021, a PCR-confirmed case of locally acquired Babesia microti infection was reported in Atlantic Canada. Clinical features were consistent with babesiosis and resolved after treatment. In a region where Lyme disease and anaplasmosis are endemic, the occurrence of babesiosis emphasizes the need to enhance surveillance of tickborne infections.PMID:35608954 | DOI:10.3201/eid2806.220443 (Source: Emerging Infectious Diseases)


Friday 25 November 2022

Borrelia multiplex: a bead-based multiplex assay for the simultaneous detection of Borrelia specific IgG/IgM class antibodies

Lyme borreliosis (LB) is the most common tick-borne infectious disease in the northern hemisphere. The diagnosis of LB is usually made by clinical symptoms and subsequently supported by serology. In Europe, a ... (Source: BMC Infectious Diseases)

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Friday 25 November 2022

IJERPH, Vol. 19, Pages 6516: Climate Changes Exacerbate the Spread of Ixodes ricinus and the Occurrence of Lyme Borreliosis and Tick-Borne Encephalitis in Europe & mdash;How Climate Models Are Used as a Risk Assessment Approach for Tick-Borne Diseases

IJERPH, Vol. 19, Pages 6516: Climate Changes Exacerbate the Spread of Ixodes ricinus and the Occurrence of Lyme Borreliosis and Tick-Borne Encephalitis in Europe—How Climate Models Are Used as a Risk Assessment Approach for Tick-Borne Diseases International Journal of Environmental Research and Public Health doi: 10.3390/ijerph19116516 Authors: Chrysa Voyiatzaki Sevastiani I. Papailia Maria S. Venetikou John Pouris Maria E. Tsoumani Effie G. Papageorgiou Climate change has influenced the transmission of a wide range of vector-borne diseases in Europe, which is a pressing public health challenge for the coming decades. Numerous theories have been developed in order to explain how tick-borne diseases are associated with climate change. These theories include highe...


Friday 25 November 2022

Increased macrophage phagocytic activity with TLR9 agonist conjugation of an anti- Borrelia burgdorferi monoclonal antibody

Clin Immunol. 2022 Nov 14:109180. doi: 10.1016/j.clim.2022.109180. Online ahead of print.ABSTRACTBorrelia burgdorferi (Bb) infection causes Lyme disease, for which there is need for more effective therapies. Here, we sequenced the antibody repertoire of plasmablasts in Bb-infected humans. We expressed recombinant monoclonal antibodies (mAbs) representing the identified plasmablast clonal families, and identified their binding specificities. Our recombinant anti-Bb mAbs exhibit a range of activity in mediating macrophage phagocytosis of Bb. To determine if we could increase the macrophage phagocytosis-promoting activity of our anti-Bb mAbs, we generated a TLR9-agonist CpG-oligo-conjugated anti-BmpA mAb. We demonstrated that our CpG-conjugated anti-BmpA mAb exhibited increased peak Bb phagoc...


Friday 25 November 2022

Bacteria and protozoa with pathogenic potential in Ixodes ricinus ticks in Viennese recreational areas

In this study we collected ticks in popular recreational areas in the city of Vienna in the years 2019 and 2020 and analyzed them for the presence of such putative pathogenic microorganisms. By using reverse line blot (RLB) hybridization we detected DNA of B. burgdorferi s. l., Rickettsia spp., Babesia spp., Candidatus Neoehrlichia mikurensis (CNM) and Anaplasma phagocytophilum. Moreover, we also screened them for the relapsing fever spirochete Borrelia miyamotoi employing real-time PCR. The most frequently detected pathogens were B. burgdorferi s. l. in 28.6% of the ticks in 2019 and 21.3% of the ticks in 2020. The genus Rickettsia was detected in 13.8% of the ticks from 2019 and only in 4.6% from 2020. Babesia spp. were detected in 5.7% in 2019 and 4.2% in 2020. Furthermore, we detected ...


Friday 25 November 2022

Supportive Oligonucleotide Therapy (SOT) as a Potential Treatment for Viral Infections and Lyme Disease: Preliminary Results

This study revealed that for Lyme Disease, one or two SOT administrations can lead to a statistically significant decrease in DNA copies, while for viruses, two or three administrations are required to achieve a statistically significant reduction in the genetic material. These preliminary results indicate that antisense SOT therapy can be considered a potential treatment for viral as well as Lyme diseases.PMID:36412742 | DOI:10.3390/idr14060084 (Source: Herpes)


Friday 25 November 2022

Utility of Whole Blood Real-Time PCR Testing for the Diagnosis of Early Lyme Disease

CONCLUSIONS: When used concurrently with serologic testing, WB-RTPCR testing increases diagnostic sensitivity in cases of ELD.PMID:35723600 | DOI:10.1093/ajcp/aqac068 (Source: American Journal of Clinical Pathology)


Friday 25 November 2022

Use of the Western blot technique to identify the immunogenic proteins of Borrelia burgdorferi for developing a Lyme disease vaccine

CONCLUSION: The strong immune response to the 41 kDa flagellin protein by the different mammalian species suggests the utility of a possible vaccine targeting this protein, although other proteins may also be appropriate, for preventing Lyme disease following a bite from an infected tick.PMID:36403566 | DOI:10.1016/j.biopha.2022.114013 (Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie)


Friday 25 November 2022

Shorter Duration of Antibiotics Noninferior for Lyme Disease

A shorter course of oral doxycycline is effective in treating erythema migrans, the most frequent manifestation of early Lyme borreliosis, and can reduce harmful antibiotic use, trialists recently reported. (Source: JAMA)


Friday 25 November 2022

023 Tick feeding on human skin represses the local immune response facilitating pathogen transmission

As a consequence of global temperature rise, ticks (Ixodida) and tick-borne diseases are emerging. During tick attachment to human skin, the feeding cavity becomes a site of transmission for tick salivary compounds, which can exert immunosuppressive effects. Tick-borne pathogens including Borrelia burgdorferi may benefit from dampened immune activation at the bite site. We therefore assessed local and circulating human immune cells and cytokine secretion upon tick bite and developed a human skin explant model mimicking Ixodes ricinus bite. (Source: Journal of Investigative Dermatology)

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Friday 25 November 2022

Imaging of Uncommon Bacterial, Rickettsia, Spirochete, and Fungal Infections

This article reviews uncommon bacterial (brucellosis, actinomycosis, neuromelioidosis, nocardiosis, whipple disease, and listeriosis), Rickettsia, spirochete (neurosyphilis and Lyme disease), and fungal (mucormycosis, aspergillosis, candidiasis, cryptococcosis, and Cladophialophora bantiana) diseases affecting central nervous system (CNS), focusing primarily on their cranial manifestations. These infections often show a variety of neuroimaging features that may be similar or differ from typical pyogenic bacterial meningitis and abscess. Familiarity with these patterns is essential for timely recognition and initiation of appropriate management. Neuroimaging is also useful for identifying complications of CNS infections and follow-up evaluation after initiation of treatment. (Source: Neuroi...


Friday 25 November 2022

Genetic variation of Borreliella burgdorferi in Fairfax County, Virginia, targeting the OspC gene in white-footed mice

In this study, five unique tissue types were sampled from 90 mice and screened for B. burgdorferi infections. This initial screening revealed a 63% overall B. burgdorferi infection rate in the mice collected (57/90). A total of 163 tissues (30.4%) tested positive for B. burgdorferi infections and when mapped to Borreliella types, 143,894 of the initial 322,480 reads mapped to 10 of the reference sequences in the ospC strain library constructed for this study at a 97% MOI. Two tissue types, the ear and the tongue, each accounted for 90% of the observed Borreliella sequence diversity in the tissue samples surveyed. The largest amount of variation was observed in an individual ear tissue sample with six ospC sequence types, which is equivalent to 60% of the observed variation seen across all ...


Friday 25 November 2022

Knowing the entire story - a focus group study on patient experiences with chronic Lyme-associated symptoms (chronic Lyme disease)

CONCLUSION: Central themes found in CLD patients' communication are 1. the experience of significant symptoms, 2. for which adequate relief is only rarely found from conventional medical practitioners, and 3. that are largely invisible to the outside world. Verbalizing these themes, patients use various repertoires for their shared experiences, such as a feeling of abandonment or not being heard by the medical system, feelings of loss with respect to their previous health, and the idea that they might have been better off had they been diagnosed sooner. Working with these repertoires will enable healthcare providers to establish a shared perspective with their CLD patients, thus engaging in more fruitful doctor-patient communication. We hypothesize that these findings are not unique to CLD...


Friday 25 November 2022

Lyme Disease, Anaplasmosis, and Babesiosis, Atlantic Canada

Emerg Infect Dis. 2022 Jun;28(6):1292-1294. doi: 10.3201/eid2806.220443.ABSTRACTIn July 2021, a PCR-confirmed case of locally acquired Babesia microti infection was reported in Atlantic Canada. Clinical features were consistent with babesiosis and resolved after treatment. In a region where Lyme disease and anaplasmosis are endemic, the occurrence of babesiosis emphasizes the need to enhance surveillance of tickborne infections.PMID:35608954 | DOI:10.3201/eid2806.220443 (Source: Emerging Infectious Diseases)


Friday 25 November 2022

IJERPH, Vol. 19, Pages 9449: Triangulating the New Frontier of Health Geo-Data: Assessing Tick-Borne Disease Risk as an Occupational Hazard among Vulnerable Populations

International Journal of Environmental Research and Public Health doi: 10.3390/ijerph19159449 Authors: Sarah P. Maxwell Connie L. McNeely Chris Brooks Kevin Thomas Determining interventions to combat disease often requires complex analyses of spatial-temporal data to improve health outcomes. For some vulnerable populations, obtaining sufficient data for related analyses is especially difficult, thus exacerbating related healthcare, research, and public health efforts. In the United States (U.S.), migrant and seasonal workers are especially affected in this regard, with data on health interventions and outcomes largely absent from official sources. In response, this study offers a multi-modal approach that involves triangulating geographically specified health data that incor...

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Friday 25 November 2022

Viruses, Vol. 14, Pages 1584: Infection with Borrelia burgdorferi Increases the Replication and Dissemination of Coinfecting Powassan Virus in Ixodes scapularis Ticks

Viruses doi: 10.3390/v14071584 Authors: Charles E. Hart Frank A. Middleton Saravanan Thangamani Powassan virus (POWV) is a tick-borne neuroinvasive flavivirus endemic to North America. It is generally transmitted by the tick, Ixodes scapularis. This species also transmits Borrelia burgdorferi, the causative agent of Lyme disease. Infection with B. burgdorferi can result in arthritis, carditis, and neuroborreliosis. These pathogens experience sylvatic overlap. To determine the risk of human exposure to coinfected ticks, the interactions between POWV and B. burgdorferi are assessed in laboratory-infected I. scapularis. Adult male and female I. scapularis ticks are orally inoculated with either both pathogens, POWV only, B. burgdorferi only, or uninfected media. After twenty-one ...

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Friday 25 November 2022

Lyme disease in a neonate complicated by the Jarisch-Herxheimer reaction

CMAJ. 2022 Jul 18;194(27):E939-E941. doi: 10.1503/cmaj.220112.NO ABSTRACTPMID:35851530 | DOI:10.1503/cmaj.220112 (Source: cmaj)

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Friday 25 November 2022

Lyme disease in a neonate complicated by the Jarisch-Herxheimer reaction

CMAJ. 2022 Jul 18;194(27):E939-E941. doi: 10.1503/cmaj.220112.NO ABSTRACTPMID:35851530 | PMC:PMC9299745 | DOI:10.1503/cmaj.220112 (Source: Canadian Medical Association Journal)


Friday 25 November 2022

Lyme neuroborreliosis: warning about the risk of false negative of CSF Borrelia burgdorferi antibody index related to high level of CSF albumin

(Source: European Journal of Clinical Microbiology and Infectious Diseases)


Saturday 19 November 2022

Guard Against Lyme Disease This Summer

SATURDAY, Aug. 1, 2020 -- Summer means higher odds of getting Lyme disease, so know how to avoid it, health experts say. Lyme disease is caused by a bacterium carried by some ticks and, if left untreated, can cause severe health problems. Ticks can... (Source: Drugs.com - Daily MedNews)


Saturday 19 November 2022

Global Lyme Alliance Reaches GuideStar ’s Highest Seal of Transparency

Platinum Seal allows donors to focus on progress and results for top Lyme disease organization(PRWeb August 10, 2020)Read the full story at https://www.prweb.com/releases/global_lyme_alliance_reaches_guidestars_highest_seal_of_transparency/prweb17313403.htm (Source: PRWeb: Medical Pharmaceuticals)

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Saturday 19 November 2022

Transforming the Global Economy or Parachuting Cats into Borneo?

Credit: United Nations Office for Disaster Risk Reduction (UNDRR)By Lawrence SurendraBANGKOK, Thailand, Aug 24 2020 (IPS) The COVID 19 Pandemic continues relentlessly. Deaths approaching a million globally, 22 million infected and growing. Brazil, India, the US and Russia accounting for almost 50% of the total cases in the world. Medically the promise of a vaccine is given as signs of hope; what surprises awaits us when such a vaccine is available, would be another story. Economically, to address the uncertainty and the grim future ahead, the UN, some governments and even Joe Biden the US Presidential hopeful, are waving “Build Back better” as ways to achieve ‘a new normal’ out of the current pandemic. “Build Back Better” emerged out of the 3rd International Conference on Disa...


Saturday 19 November 2022

Can Lyme Disease be Cured

? (Source: eMedicineHealth.com)


Saturday 19 November 2022

Late-Stage Lyme Disease and Psychiatric Illness: Final Verdict? Late-Stage Lyme Disease and Psychiatric Illness: Final Verdict?

Patients with Lyme neuroborreliosis, a late-stage manifestation of Lyme disease, may develop psychiatric illness, but new research suggests that when symptoms do develop, they tend to resolve within a year.Medscape Medical News (Source: Medscape Internal Medicine Headlines)


Saturday 19 November 2022

Yale scientists identify protein that protects against Lyme disease

The newly identified protein acts like an early warning signal to the immune system when exposed to the bacteria at causes Lyme disease. (Source: Yale Science and Health News)


Saturday 19 November 2022

Mayo Clinic Minute: Will there be a Lyme disease vaccine for humans?

(Source: MayoClinic.com Full Feed)

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Saturday 19 November 2022

Brandon Jutras receives Emerging Leader Award to advance Lyme disease research

(Virginia Tech) The awards are designed to support established and up-and-coming scientists who have identified new and defined approaches to improve diagnostics or therapeutics for Lyme disease. (Source: EurekAlert! - Medicine and Health)


Saturday 19 November 2022

It's Tick Season: 5 Things to Know About Lyme Disease Tests It's Tick Season: 5 Things to Know About Lyme Disease Tests

Prepare for tick season by reviewing these five things to know about Lyme disease testing.CDC Expert Commentary (Source: Medscape Infectious Diseases Headlines)


Saturday 19 November 2022

Amid recent tick population surge in CNY, U. S. Rep. Katko highlights efforts to combat tick-borne illness like those underway at Upstate Medical

One element of Upstate's work on Lyme disease and ticks is it's wildly successful tick identification program. Since April, more than 13,000 ticks have been sent to Upstate, with nearly one-third carrying some sort of infectious disease. (Source: SUNY Upstate Medical)

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Saturday 19 November 2022

Spending More Time Outside During The Pandemic? Scientists Say Beware Of Ticks.

With Lyme disease on the rise, people need to take special care to avoid tick encounters amid the COVID-19 crisis. (Source: Science - The Huffington Post)


Saturday 19 November 2022

It's Tick Season: Protect Yourself From Lyme Disease

SUNDAY, July 25, 2021 -- When you're heading outdoors this summer, keep an eye out for ticks during and after your outing, health experts say. These common parasites can transmit Lyme disease, a potentially serious illness. Lyme disease is... (Source: Drugs.com - Daily MedNews)


Saturday 19 November 2022

Cracking the Lyme disease code

(Washington State University) The next time a tick feeds on you, Washington State University researchers hope to make sure persistent arthritis caused by Lyme disease doesn't linger for a lifetime. (Source: EurekAlert! - Medicine and Health)


Saturday 19 November 2022

Lyme borreliosis and associations with mental disorders and suicidal behavior: a nationwide Danish cohort study - Fallon BA, Madsen T, Erlangsen A, Benros ME.

OBJECTIVE: Lyme borreliosis is a tick-borne infectious disease that may confer an increased risk of mental disorders, but previous studies have been hampered by methodological limitations, including small sample sizes. The authors used a nationwide retrosp... (Source: SafetyLit)


Saturday 19 November 2022

How to Prevent Tick Bites and Lyme Disease

by Sarah Elizabeth Adler, AARP, Updated July 14, 2020 | ... En espa ñol | Ticks: They're the tiny pests that stop outdoor fun in its tracks — and experts say they stay active well into fall, making ... (Source: AARP.org News)


Saturday 19 November 2022

Why Tick Season Could Be Worse In The Summer Of COVID-19

(CNN) — After more than three months of shutdowns, mandatory quarantines, self-imposed exile from society and working from home, nature-lovers looking for a well-earned breath of fresh air could face a possible collision course between coronavirus and tick-borne illnesses this summer. A “perfect storm,” warns Eva Sapi, a University of New Haven biology professor and group director for the Lyme Disease Research Group. Noting the mild winter on the East Coast, Sapi says, “We do have a bad year for the ticks.” Hikers, campers and anyone else eager for an escape could “just explode into the outdoors. And there may not be the same thoughtful approach” to preventing exposure, explains Dr. Sorana Segal-Maurer, director of the Dr. James J. Rahal, Jr. Divi...


Saturday 19 November 2022

Raking Your Leaves to the Edge of Your Yard an Invitation to Ticks

SUNDAY, March 22, 2020 -- Where you put leaves raked from your yard last fall could affect your family's risk of bites from ticks that transmit Lyme disease-causing bacteria, a new study suggests. In areas where Lyme-causing ticks are prevalent,... (Source: Drugs.com - Daily MedNews)


Saturday 19 November 2022

Lyme disease ticks produce antibiotic that protects them from human skin bacteria

(University of California - San Francisco) Ticks live dangerous lives, spending most of their time questing for a host across wildly different habitats and seasons. Once they encounter a reptile, bird, or a mammal like us, they become intimately connected with it -- and all of its bacteria and viruses -- for days on end. Though ticks are notorious for transmitting pathogens such as the Lyme disease bacterium, how does their immune system keep them safe from contracting pathogens themselves? (Source: EurekAlert! - Infectious and Emerging Diseases)


Saturday 19 November 2022

Updated'Be tick aware' toolkit: Raising awareness of the potential risk posed by ticks and tick-borne disease in England

This updated toolkit provides background information on ticks, Lyme disease risk, how to improve awareness of ticks and mitigate against tick-borne diseases through the promotion of Public Health England's key message which is to'be tick aware'. (Source: Current Awareness Service for Health (CASH))


Saturday 19 November 2022

Help in the fight against Lyme disease

Lyme disease is a bacterial infection caused by the bite of an infected black-legged tick, commonly known as a deer tick. Preventing tick bites is the best defense against the disease. And now there is good news for those looking for an alternative insect repellant to fight off ticks, says Dr. Omar Abu Saleh, a Mayo Clinic [...] (Source: News from Mayo Clinic)


Saturday 19 November 2022

How This Founder Went From Serving People With Lyme Disease To Serving The One In Three People With Chronic Conditions

Supporting entrepreneurs can take many forms from grants to providing access to capital and from expanding their networks of mentors and peers to providing training that addresses both hard and soft skills. (Source: Forbes.com Healthcare News)

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Saturday 19 November 2022

$1.8M to advance device for detecting COVID-19, cancer, contaminants

(University of Arizona College of Engineering) In her Little Sensor Lab, University of Arizona professor Judith Su is working to sense single molecule amounts of 'anything worth sensing' -- including biomarkers for cancer, Alzheimer's disease, Lyme disease and even COVID-19. (Source: EurekAlert! - Medicine and Health)

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Saturday 19 November 2022

July 2021

App Helps Screen for Autism Spectrum Disorder Step It Up! : Get Active for Your Health Disruptive Leg Movement? : Managing Restless Legs Syndrome Protect Yourself From Lyme Disease Noisy Planet (Source: NIH News in Health)


Saturday 19 November 2022

Ticks and Lyme Disease: Symptoms, Treatment, and Prevention

Lyme disease is on the rise. How can you prevent it? What are the symptoms, and what should you do if you think you or your pet have it? (Source: FDA Center for Drug Evaluation and Research - What's New)


Saturday 19 November 2022

Tipping Point: The Resistance Is Gaining In The Lyme Wars

Mainstream medicine has failed many Lyme disease patients. It's fast becoming irrelevant. (Source: Forbes.com Healthcare News)


Saturday 19 November 2022

Lyme disease symptoms: How do you get Lyme disease? Is it contagious?

LYME DISEASE is normally harmless, but if it is left untreated it can be deadly. How do you get Lyme disease? (Source: Daily Express - Health)


Saturday 19 November 2022

Las garrapatas y la enfermedad de Lyme: s íntomas, tratamiento y prevención

La enfermedad de Lyme est á proliferando. ¿Cómo puede prevenirla? ¿Cuáles son los síntomas y qué debe hacer si cree haberla contraído? (Source: FDA Center for Drug Evaluation and Research - What's New)

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Saturday 19 November 2022

Fashion model, 27, claims CBD has helped her ditch medication for crippling Lyme disease

EXCLUSIVE: Kelly Brooks, 27, of Hampshire, suffers from chronic Lyme disease - a tick-borne condition that has severe symptoms including agonising joint pain, fatigue and headaches. (Source: the Mail online | Health)


Saturday 19 November 2022

Lyme disease symptoms: The sign in your knees you may have been bitten by an infected tick

LYME disease is a bacterial infection that is passed on to humans by infected ticks. High-risk areas include grassy and wooded areas, making that leisurely stroll not seem so idyllic any more. Look for a sign on your knee that you may be needing a visit to your doctors pronto. (Source: Daily Express - Health)


Saturday 19 November 2022

Lyme disease continues to spread. Can a seasonal shot help slow the spread of the tick-borne illness?

With no vaccine against Lyme right now, the author and his colleagues are working to create seasonal protection. (Source: Washington Post: To Your Health)


Saturday 19 November 2022

We Used to Have a Lyme Disease Vaccine. Are We Ready to Bring One Back?

At my animal hospital in upstate New York, an epicenter of the U.S. tick epidemic, my dog Fawn lets out a whimper as the veterinarian injects her with her annual Lyme disease shot. I roll my eyes. She doesn’t know how good she has it. The injection means that if a tick bites her (and in rural New York, a tick always does), the creepy crawly will feast on dog blood that’s been supercharged with a Lyme bacteria-killing substance, and Lyme disease won’t be transmitted to Fawn. I wish I could be shot up with that superpower. Currently, there is no human vaccine for Lyme disease—even though more than two decades ago, people could get a safe and effective preventative shot similar to Fawn’s. Now, thanks to potent anti-vaccine pushback, all we can do is try to avoid ...


Saturday 19 November 2022

WNBA ’s Elena Delle Donne Is ‘Hurt’ League Denied Her a Medical Waiver Despite Taking 64 Pills a Day

(NEW YORK) — WNBA MVP Elena Delle Donne was shocked and hurt when her request to be medically excused for the season was denied by an independent medical panel. Having battled Lyme disease for more than a decade and now taking 64 pills a day, she thought she was definitely going to be considered high-risk to get severe illness if she contracted the coronavirus. The panel of independent doctors the league and union agreed upon to make that decision thought otherwise, ruling Monday that she was not “high risk, and should be permitted to play in the bubble.” The disease is not included on the Centers for Disease Control and Prevention’s list of underlying conditions that could put someone at an increased risk for severe illness from COVID-19. The Washington Mystics st...

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Saturday 19 November 2022

Lyme disease symptoms: A certain feeling in the head could be a warning sign

LYME disease is a bacterial infection which could lead to severe physical and mental problems if not diagnosed at an early stage. Spotting the early warning signs will ensure prompt treatment and noticing this peculiar feeling in the head could mean you're at risk. (Source: Daily Express - Health)


Saturday 19 November 2022

What Happens if You Go Untreated for Lyme Disease?

Title: What Happens if You Go Untreated for Lyme Disease?Category: Diseases and ConditionsCreated: 6/17/2020 12:00:00 AMLast Editorial Review: 6/29/2020 12:00:00 AM (Source: MedicineNet Arthritis General)


Saturday 19 November 2022

A Quick Tour of the New Lyme Disease Guideline A Quick Tour of the New Lyme Disease Guideline

Dr Paul Auwaerter highlights the major changes in this guideline, which was a collaboration of the IDSA, AAN, and ACR.Medscape Infectious Diseases (Source: Medscape Infectious Diseases Headlines)


Saturday 19 November 2022

Recommendations Developed for Management of Lyme Disease

FRIDAY, Dec. 11, 2020 -- In new evidence-based clinical practice guidelines, published online Nov. 30 in Clinical Infectious Diseases, recommendations are presented for the prevention, diagnosis, and treatment of Lyme disease. The guidelines were... (Source: Drugs.com - Pharma News)


Saturday 19 November 2022

Lyme Disease Found In More Than A Third Of Maine Deer Ticks

ORONO, Maine (AP) — More than a third of the deer ticks submitted to a Maine lab last year tested positive for Lyme disease, a surveillance report from the lab said. The report is from the University of Maine Tick Lab. The lab found that a smaller percentage of ticks tested positive for anaplasmosis and babesiosis, which are other tick-borne diseases. The tick lab’s manager, Griffin Dill, said the information will help authorities learn how fast the ticks are spreading in the state. The study is the first of its kind in Maine, the Bangor Daily news reported. The report found that just shy of 39% of deer ticks tested positive for Lyme. The data also show ticks were more frequently found higher on the bodies of children than adults. Lyme disease can cause symptoms such as neck stiffn...


Saturday 19 November 2022

Joint Guidelines Favor Antibody Testing for Lyme Disease Joint Guidelines Favor Antibody Testing for Lyme Disease

New clinical practice guidelines on Lyme disease place a strong emphasis on antibody testing to assess for rheumatologic and neurologic syndromes.Medscape Medical News (Source: Medscape Infectious Diseases Headlines)


Saturday 19 November 2022

Updates in Clinical Practice Guidelines for Lyme Disease Updates in Clinical Practice Guidelines for Lyme Disease

Recent guidance from several specialty societies can answers many patients'questions and aid clinical decision-making regarding tick bites.Medscape Family Medicine (Source: Medscape Infectious Diseases Headlines)


Saturday 19 November 2022

Yale scientists identify protein that protects against Lyme

(Yale University) Yale researchers have discovered a protein that helps protect hosts from infection with the tick-borne spirochete that causes Lyme Disease, a finding that may help diagnose and treat this infection, they report Nov. 11 in the journalPLOS Pathogens. (Source: EurekAlert! - Medicine and Health)

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Saturday 19 November 2022

Portable lab you plug into your phone can diagnose illnesses like coronavirus

Engineers with the University of Cincinnati have created a tiny portable lab that plugs into your phone, connecting it automatically to a doctor's office through a custom app UC developed. The lab the size of a credit card can diagnose infectious diseases such as coronavirus, malaria, HIV or Lyme disease or countless other health conditions like depression and anxiety. (Source: World Pharma News)

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Saturday 19 November 2022

What Causes Joint Pain?

DiscussionMusculoskeletal problems are common problems in pediatric practice with up to 15% of acute care visits being for this problem. Joint pain is a common concern for families but the differential diagnosis is extensive and needs thoughtful consideration. History is a key to discerning the potential diagnosis but also in guiding the physical examination and laboratory examination. Family history especially for systemic diseases should be considered. On physical examination all joints should be examined include sacroiliac and temporomandibular joints. Is this arthritis or arthralgia? Distinction between inflammatory and non-inflammatory joints is important. Joints with inflammation are painful or stiff after rest and improve with activity. Joints without inflammation are better afte...


Saturday 19 November 2022

Lyme Disease-Carrying Ticks Are Turning Up On California's Beaches

The blood-sucking critters are capable of thriving along the western coast, according to new research. Though experts don't exactly know how they're picking up the bacteria that causes the illness.(Image credit: James Gathany/AP) (Source: NPR Health and Science)


Saturday 19 November 2022

Have We Been Thinking About Long-Haul Coronavirus All Wrong?

A few years ago, Jaime Seltzer was helping coordinate research projects, grant applications and funding for a Stanford research group studying a condition called myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Up to 2.5 million Americans, including Seltzer, have ME/CFS, and yet it felt like almost no one paid attention to her group’s research. “What is it going to take for researchers to take ME seriously?” she and her colleagues often wondered aloud. The morbid answer, they hypothesized, was a pandemic. Since ME/CFS often follows viral infections, they feared it would take something as destructive as mass illness for the larger scientific community to take notice. Unfortunately, this year they were proven right. As the COVID-19 pandemic presses on, doctors ...


Saturday 19 November 2022

Maine Had Record Number Of Lyme Disease Cases In 2019

AUGUSTA, Maine (AP) — Maine reported a record number of Lyme disease cases last year, and the number could rise as data continues to trickle in, officials said Thursday. There were at least 2,079 cases in 2019, the Maine Center for Disease Control and Prevention reported. It’s too early to say why the numbers grew last year. But the numbers underscore the importance of taking precautions to avoid tick bites, said Dr. Nirav Shah, director of the Maine CDC. Winter is a time of low ticket activity. But ticks can be active when the temperature climbs above 40, as it did last weekend in Maine. The state also experienced increases in two other tickborne diseases, with 685 cases of anaplasmosis and 138 cases of babesiosis. Lyme disease is caused by bacteria carried by infected deer ticks....


Saturday 19 November 2022

Veterinary college receives $3.5 million NIH grant to develop Lyme disease vaccine

(Virginia Tech) Renowned tick immunobiologist Utpal Pal wants to adapt the rabies vaccination platform to produce antibodies that can protect against Borrelia burgdorferi, the bacteria responsible for Lyme disease. The intention is to apply this work to other tick-borne diseases in the future. (Source: EurekAlert! - Medicine and Health)


Saturday 19 November 2022

Ticks on a 'quest' for blood at California's beaches. Is Lyme disease a rising risk?

Lyme disease-carrying ticks usually found in woodlands and fields are spreading along California's beaches, carried by an unknown host. (Source: Los Angeles Times - Science)

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Saturday 19 November 2022

Bat tick found for the first time in New Jersey

(Rutgers University) A tick species associated with bats has been reported for the first time in New Jersey and could pose health risks to people, pets and livestock, according to a Rutgers-led study in the Journal of Medical Entomology. This species (Carios kelleyi) is a " soft " tick. Deer ticks, which carry Lyme disease, are an example of " hard " ticks. (Source: EurekAlert! - Infectious and Emerging Diseases)


Saturday 19 November 2022

Lyme disease like 'waking with a hangover' every day

A engineer forced to quit work hopes pop star Justin Bieber will raise awareness of the condition. (Source: BBC News | Health | UK Edition)

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Saturday 19 November 2022

How to Stop the Next Pandemic

It ’s not just Covid-19. Pathogens once confined to nature are making their way into humans on a more regular basis. And it’s our fault. (Source: NYT Health)

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Saturday 19 November 2022

Lyme Disease: Testing, Prophylaxis, and Treatment Lyme Disease: Testing, Prophylaxis, and Treatment

From what to do when a patient presents with a tick, to which antibiotic to select for treatment.Medscape Family Medicine (Source: Medscape FamilyMedicine Headlines)


Saturday 19 November 2022

What Do Coronavirus And Lyme Disease Have In Common? More Than You Might Think

Lyme and Covid-19 are replacing syphilis as the great masquerader. They share many puzzling symptoms and are all easily missed. (Source: Forbes.com Healthcare News)


Saturday 19 November 2022

Justin Bieber ’s Lyme Disease Reveal, Why It Is A Tough Diagnosis

Here is why Lyme Disease is tough to diagnose, tough to understand, and tough to have. (Source: Forbes.com Healthcare News)


Saturday 19 November 2022

Citrus Flavoring Is Weaponized Against Insect-Borne Diseases

The E.P.A. has approved nootkatone, which is found in cedars and grapefruit. It repels ticks, mosquitoes and other dangerous bugs for hours, but is safe enough to eat. (Source: NYT Health)


Saturday 19 November 2022

Babesiosis, a dangerous tick-borne infection that attacks red blood cells, appears to be a growing problem

The disease is most often caused by the tiny parasites and transmitted to humans in warmer months by deer ticks — the same ones that spread Lyme disease. (Source: Washington Post: To Your Health)


Saturday 19 November 2022

Ticks and mosquitoes may await the pandemic-weary seeking outdoor exercise

Insects can pass along serious illnesses, such as Lyme disease and West Nile virus. Because of covid-19, health agencies are focusing less on these problems. (Source: Washington Post: To Your Health)


Saturday 19 November 2022

Justin Bieber looks like a drug addict, fans said. Then the singer revealed he has Lyme disease.

More details about his affliction will be unveiled in an upcoming documentary series, Bieber said. (Source: Washington Post: To Your Health)


Saturday 19 November 2022

Lyme disease symptoms: Six lesser-known warning signs you may be infected

LYME disease is a debilitating bacterial infection and with lockdowns easing and more people venturing outside, knowing the potential risks and symptoms is extremely important. If you experience any of these six, lesser-known warning signs you may be at risk. (Source: Daily Express - Health)


Saturday 19 November 2022

Man says his legs looked like a'zombie' after two tick bites gave him different diseases 

Don Murry Grubbs, from White House, Tennessee was diagnosed with two tick-borne illnesses - Lyme disease and Rocky Mountain Spotted Fever - after being bitten by two different ticks. (Source: the Mail online | Health)


Saturday 19 November 2022

New State Law Sets Up Group to Study Lyme Disease Testing New State Law Sets Up Group to Study Lyme Disease Testing

New Hampshire has signed into law a bill that establishes a commission to study the limitations of current testing for Lyme disease and other tick-borne illnesses and available treatment.Associated Press (Source: Medscape Infectious Diseases Headlines)

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Saturday 19 November 2022

Health Highlights: Jan. 9, 2020

Here are some of the latest health and medical news developments, compiled by the editors of HealthDay: Justin Bieber Reveals He Has Lyme Disease Singer Justin Bieber says he has Lyme disease. He revealed his condition Wednesday in an Instagram... (Source: Drugs.com - Daily MedNews)


Saturday 19 November 2022

Lyme disease: Feeling this sensation in your head could mean an infection by a tick bite

LYME disease is a bacterial infection which is transmitted by a tick bite. Feeling this sensation in your head could mean you're at risk. (Source: Daily Express - Health)


Saturday 19 November 2022

Trista Sutter ’s husband Ryan reveals his mystery illness is Lyme disease

The former “Bachelorette” winner has Lyme disease that was triggered by high levels of mold in his body, he shared on wife Trista... (Source: Reuters: Health)

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Saturday 19 November 2022

Evita las picaduras de garrapatas y la enfermedad de Lyme

Pasos para ayudar a prevenir las picaduras y las enfermedades. ... por: Sarah Elizabeth Adler, AARP, 14 de julio de 2020 | ... In English | Garrapatas: Son las peque ñas plagas que interrumpen la di... (Source: AARP.org News)


Saturday 19 November 2022

Immunoassay May Help Identify Pediatric Lyme Arthritis Immunoassay May Help Identify Pediatric Lyme Arthritis

In Lyme disease-endemic areas, a C6 peptide enzyme immunoassay (EIA) test may help guide initial management of children with acute arthritis, an observational study suggests.Reuters Health Information (Source: Medscape Orthopaedics Headlines)


Saturday 19 November 2022

She Tested Negative for Lyme Disease. So What Was Wrong?

Her lethargy and joint pain suggested a tick-borne illness. Adding to the mystery, was a recent trip abroad a clue or a red herring? (Source: NYT Health)


Saturday 19 November 2022

UMD awarded funds to head off tick-borne infection before it begins

(University of Maryland) The University of Maryland (UMD) received funding from the Steven& Alexandra Cohen Foundation to develop novel therapeutic strategies to stop infection from Lyme disease pathogens before it begins. Unlike traditional antibiotics that attack the pathogen directly and put it on the defensive, UMD is exploring antimicrobials that would interfere with the pathogen on a biomolecular level to inhibit it from causing an infection in the first place. (Source: EurekAlert! - Infectious and Emerging Diseases)


Saturday 19 November 2022

A 360-degree approach to Lyme disease

(Harvard Medical School) A $5 million donation to Harvard Medical School will propel Lyme disease research, education (Source: EurekAlert! - Medicine and Health)



Saturday 19 November 2022

Lyme disease symptoms: An early sign of the bacterial infection to look out for

LYME disease is a bacterial infection that can be spread to humans by infected ticks, tiny spider-like creatures that dwell in woodland. Untreated Lyme disease can cause a host of debilitating health problems so it is vital to act on the early warning sign. (Source: Daily Express - Health)

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Saturday 19 November 2022

Lyme disease symptoms: How common is lyme disease in the UK?

LYME DISEASE is an infection spread by ticks and is potentially life-threatening. How common is lyme disease in the UK? (Source: Daily Express - Health)


Saturday 19 November 2022

What Are the 3 Stages of Lyme Disease

? (Source: eMedicineHealth.com)

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Saturday 19 November 2022

Insurance claims related to Lyme disease up by 117 percent in U.S.

Insurance claim lines related to Lyme disease, a bacterial infection transmitted through the bite of black-legged ticks, increased by 117 percent across the country between 2007 and 2018, according to new research. (Source: Health News - UPI.com)


Saturday 19 November 2022

No, Lyme disease is not an escaped military bioweapon, despite what conspiracy theorists say

Some tick-spread bacteria could be weaponized — but this would be a pretty useless choice. (Source: Washington Post: To Your Health)

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Saturday 19 November 2022

‘Ticks Surprise Us:’ 2021 May Be Big Lyme Disease Year

This winter was one of the warmest on record, and lingering summer heat could add weeks of outdoor activity to animals that carry ticks, which thrive in hot, humid conditions. (Source: WebMD Health)


Saturday 19 November 2022

Student, 22, shares video of her seizures caused by Lyme disease

Steph Todd, from Thornbury in Gloucestershire, said people say her seizures make it look like she is 'possessed' and that she desperately wants treatment in the US. (Source: the Mail online | Health)


Saturday 19 November 2022

Lyme disease claim lines increased 117% from 2007 to 2018

(FAIR Health) From 2007 to 2018, claim lines with diagnoses of Lyme disease increased nationally 117%. The new FAIR Health Study Uncovers Geographic, Age and Gender Variation, among Other Notable Statistics. Comparing Lyme disease to other tick-borne diseases, the study draws on data from FAIR Health's comprehensive repository of over 29 billion private healthcare claim records -- the largest in the country. (Source: EurekAlert! - Infectious and Emerging Diseases)


Saturday 19 November 2022

The Lyme Wars, Part 2: Which Way Should We Treat?

We know far too little about Lyme and how to diagnose it, let alone have agreement between major advisory groups as to how to treat the disease. (Source: Forbes.com Healthcare News)


Saturday 19 November 2022

2021 May Be Big Lyme Disease Year 2021 May Be Big Lyme Disease Year

For the first time, Lyme disease-carrying ticks -- typically associated with woodlands in New England and other forested regions of the US -- have been found in abundance near beaches in Northern California, new research shows.WebMD Health News (Source: Medscape Infectious Diseases Headlines)


Saturday 19 November 2022

Walking in woods or tall grass? Check yourself for ticks every day

As tick populations take hold permanently in large swaths of Canada, more people will be exposed and contract Lyme disease. (Source: CBC | Health)


Saturday 19 November 2022

New test for Lyme disease could spot the tick-borne infection in just 15 minutes 

Scientists at Columbia University, New York, are developing test that uses microchips to detect antibodies against Lyme disease. The condition, spread by ticks, can be fatal to humans. (Source: the Mail online | Health)


Saturday 19 November 2022

Lyme disease: Warning of cases of the disease on the rise in the UK - do you have it?

LYME DISEASE is on the rise according to Doctor Hilary on Lorraine with new cases of the disease everyday. What is it and how to know if you might have it? (Source: Daily Express - Health)


Saturday 19 November 2022

Lyme Disease Pathogen Present in Ticks Near the Coast

In Northern California, the proportion of ticks infected with the bacterium Borrelia burgdorferi was the same in shrubland along beaches as in woodland habitats. (Source: The Scientist)

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Saturday 19 November 2022

Lyme Disease outbreak: What are the symptoms of lyme disease? How to tell if YOU have it

LYME DISEASE is currently on the rise, as scientists have found there could be far more cases of the disease than previously estimated. What are the symptoms of Lyme disease? (Source: Daily Express - Health)

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Saturday 19 November 2022

Lyme Disease and Tick-Borne Infections: A Neurologist's View Lyme Disease and Tick-Borne Infections: A Neurologist's View

Fundamental misunderstandings exist among both patients and practitioners about the nature of tick-borne infections. This review aims to address these issues from the neurologist's perspective.Seminars in Neurology (Source: Medscape Today Headlines)


Saturday 19 November 2022

Lexington diagnostics maker T2 Biosystems' stock plummets on CEO departure, low earnings

Lexington sepsis and lyme disease diagnostics maker T2 Biosystems will need a new CEO to lead it through its ongoing financial struggles. T2 Biosystems (Nasdaq: TTOO) reported after markets closed Tuesday that CEO John McDonough will be stepping down from his role to become executive chairman of the company's board of directors. He will stay in the CEO role until the company hires his successor, according to a press release. McDon ough has been in the top job at T2 since 2007, leading T2 Biosystems… (Source: bizjournals.com Health Care:Biotechnology headlines)


Saturday 19 November 2022

Study finds Lyme-carrying ticks next to beaches and ‘pretty much wherever we looked’

"I don’t think we were expecting to find many ticks, but we did, and we found heaps of ticks in big numbers. And they’re infected with diseases," the study's lead author said. (Source: Washington Post: To Your Health)


Saturday 19 November 2022

Lyme disease may be three times more common in UK than previously thought

New cases of tick-borne Lyme disease might top 8000 in 2019, researchers estimate Related items fromOnMedica Well over half of people have never had an STI test HPV programme linked to dramatic fall in cervical disease Should we have compulsory measles vaccination at school entry? Promise to end new HIV transmissions in England by 2030 Decision to give boys HPV jab will save thousands of lives (Source: OnMedica Latest News)


Saturday 19 November 2022

Tireless Teen Takes Ticks To Task

Fewer than 40% of those bitten by a tick transmitting Lyme disease will have a bullseye rash, and ticks are incredibly small (about the size of a sesame seed), so are easily missed. (Source: Forbes.com Healthcare News)

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Saturday 19 November 2022

The tell-tale sign of Lyme disease: Mother's photo of her 'bullseye' rash after walking her dog

Kate Allen, 28, from Leicester, spotted raised bumps on her skin after walking her dog through long grass in the park in 30°C. Lyme disease is spread by tick bites. (Source: the Mail online | Health)


Saturday 19 November 2022

Phage-Targeting PCR Test Picks Up Early Lyme Disease Phage-Targeting PCR Test Picks Up Early Lyme Disease

Promising data show that a viral gene in the Lyme disease-causing bacteria can distinguish between early and late infection.Medscape Medical News (Source: Medscape Rheumatology Headlines)


Saturday 19 November 2022

The Challenge of Diagnosing Lyme Disease

The biggest problem is that there is no way to test, unequivocally, for the presence of the bacteria that cause the disease. (Source: NYT Health)


Saturday 19 November 2022

Lyme disease symptoms: The major warning sign that could signal you have the condition

LYME disease is an infectious disease caused by a bacterium named Borrelia, spread by ticks found in the woods. It can easily be caught and if a person experiences this one particular sign it could be a major warning that you may be at risk of having the disease. What is it? (Source: Daily Express - Health)


Saturday 19 November 2022

Lyme disease symptoms: How to tell if you’ve been bitten - the three signs

LYME DISEASE is known as a form of arthritis caused by bacteria that is transmitted by ticks. If detected early it can often be treated effectively. What are the three signs you may have Lyme disease? (Source: Daily Express - Health)

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Saturday 19 November 2022

Columbia establishes treatment center, clinical trials network for Lyme disease

(Columbia University Irving Medical Center) With a $16 million gift from the Steven& Alexandra Cohen Foundation, Columbia will open a center for Lyme and other tick-borne diseases this summer, offering patients specialized care and expanding research at a national level. (Source: EurekAlert! - Infectious and Emerging Diseases)


Saturday 19 November 2022

Maine Reports Its First Case Of Rare Tick-Borne Powassan Virus Since 2017

(CNN) — Health officials in Maine are warning about the potential for more cases of Powassan virus disease after one person was confirmed to be sick with the rare tick-borne illness, the first reported case in the state since 2017. The Maine Center for Disease Control and Prevention said Wednesday that a person in the southern part of the state had Powassan encephalitis, a severe disease that causes inflammation in the brain. The agency said the patient showed symptoms in late June and was hospitalized. The Maine CDC issued an advisory to physicians that more cases could be possible and suggested that doctors consider testing for the disease in patients with unexplained encephalitis, meningitis or high fever during the summer and early fall. Powassan virus disease is spread by three ...


Saturday 19 November 2022

Risk Factors for Diseases Associated With Black-Legged Ticks Risk Factors for Diseases Associated With Black-Legged Ticks

As vectors for Lyme disease, black-legged ticks present a public health crisis in North America. Are current prevention recommendations appropriate? Where should prevention efforts be focused?American Journal of Epidemiology (Source: Medscape Today Headlines)


Saturday 19 November 2022

Mouse, not just tick: New genome heralds change in Lyme disease fight

(University of California - Irvine) As Lyme disease increases, researchers have taken a significant step toward finding new ways to prevent its transmission. The experts, who include a pioneer in Lyme disease discovery, have sequenced the genome of the animal carrying the bacteria that causes the illness. The advance by researchers at the University of California, Irvine and colleagues provides a launching pad for fresh approaches to stopping Lyme disease from infecting people. (Source: EurekAlert! - Infectious and Emerging Diseases)


Saturday 19 November 2022

New study predicts changing Lyme disease habitat across the West Coast

(The Translational Genomics Research Institute) The findings of a recent analysis conducted by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest that ecosystems suitable for harboring ticks that carry debilitating Lyme disease could be more widespread than previously thought in California, Oregon and Washington. Bolstering the research were the efforts of an army of " citizen scientists " who collected and submitted 18,881 ticks over nearly three years. (Source: EurekAlert! - Infectious and Emerging Diseases)


Saturday 19 November 2022

Lyme disease: is a solution on the way?

The tick-borne illness, which is on the rise, can have chronic side-effects. So why hasn ’t more effort been put into a cure?As a former martial arts world champion, who trained daily and enjoyed camping and hiking at weekends, Stephen Bullough had always prided himself on leading a healthy life.Like most people, he thought very little when he was bitten by a tick on a camping holiday close to home in Wigan in 2014, never suspecting that this tiny bite would unleash an infection in his body that would one day leave him permanently incapacitated.Continue reading... (Source: Guardian Unlimited Science)


Saturday 19 November 2022

Suspect Lyme Carditis? Start Empiric Antibiotics Suspect Lyme Carditis? Start Empiric Antibiotics

Waiting for test results before initiating therapy for patients suspected of having Lyme carditis may result in death, data from two recent cases show.Medscape Medical News (Source: Medscape Internal Medicine Headlines)


Saturday 19 November 2022

What ’s really behind the spread of Lyme disease? Clue: it’s not the Pentagon | Peter Beaumont

After my tick bite I realised that the climate crisis was a more likely culprit than any conspiracy theory about weaponisationThe first indication I ’d picked up a tick-borne disease three years ago was the excruciating arthritic pain in my feet as I hobbled to a dinner party at a neighbour’s house in Jerusalem.Later that night I experienced flu-like symptoms, including a raging fever that, even with antibiotics, would last for more than a week.Continue reading... (Source: Guardian Unlimited Science)


Saturday 19 November 2022

Five herbal medicines potent against tick-borne disease babesiosis in lab, says new study

(TellMed Strategies) Bay Area Lyme Foundation, a leading sponsor of Lyme disease research in the U.S., today announced the publication of new data finding that five herbal medicines had potent activity compared to commonly-used antibiotics in test tubes against Babesia duncani, a malaria-like parasite found on the West Coast of the U.S. that causes the disease babesiosis. (Source: EurekAlert! - Infectious and Emerging Diseases)

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Saturday 19 November 2022

Did the US military cause Lyme disease on PURPOSE?

Politicians in the US have ordered the military to reveal details of a programme believed to have tried to 'weaponise' ticks, which may have led to them escaping and spreading Lyme disease. (Source: the Mail online | Health)

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Saturday 19 November 2022

Scientists work toward a rapid point-of-care diagnostic test for Lyme disease

Rapid assay for Lyme disease could lead to a practical test for use by healthcare providers. (Source: National Institutes of Health (NIH) News Releases)


Saturday 19 November 2022

Diagnose and treat Lyme disease if bull ’s eye rash is present, says NICE

People presenting erythema migrans, the characteristic skin rash associated with Lyme disease, can be diagnosed and treated without the need for blood tests, NICE has said in a final quality standard published this week. (Source: NHS Networks)


Saturday 19 November 2022

Lyme disease misinterpreted as child abuse - Pan T, Nasreddine A, Trivellas M, Hennrikus WL.

Child abuse is one of the most common causes for child fatality in the United States. Inaccurate reporting of child abuse combined with scarcity of resources for child abuse evaluations can lead to unintended consequences for children and their families. T... (Source: SafetyLit)


Saturday 19 November 2022

Lyme disease: Having this feeling in your head could mean you are at risk

LYME DISEASE is an infectious disease caused by a bacterium named Borrelia, spread by ticks. It can easily be caught and having a feeling in your head could mean you have the disease. (Source: Daily Express - Health)


Saturday 19 November 2022

How Common is Lyme Disease Globally and in Urban Settings?

Discussion Lyme disease (LD) is caused by several genospecies of Borrelia burgdorferi senu lato that are transmitted by ticks of the Ixodes ricinus complex. In the U.S. and Europe it is the most common vector-borne disease. It is named for Lyme, Connecticut in the 1970s when it was “discovered,” but there are reports of LD-type disease in Europe since 1883. There are 18 distinct genospecies with B. afzelii, B. garinii and B. burgdorferi sensu stricto being the 3 most common ones causing human infection. There are many species of Ixodes ticks but only 4 commonly bite humans. Ixodes ricinus mainly in Europe, I, persultcatus in Asia, I. scapularis in the eastern and central US, and I. pacificus in the western US and Canada. However I. pacificus is rarely infected and accounts for ...

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Saturday 19 November 2022

6 Essential Updates in Lyme Disease Research

With the start of peak tick season, check here to spot some of the latest developments in diagnosis and treatment of Lyme disease. (Source: ConsultantLive)


Saturday 19 November 2022

Royal Mint to commemorate fossil hunter Mary Anning

Special 50p coins will feature some of the Jurassic creatures discovered by 19th-century palaeontologistOne of the most terrifying Jurassic sea creatures is to appear on commemorative 50p coins to celebrate the work of thepioneering fossil hunter Mary Anning.The temnodontosaurus coins will shine a light on the 19th-century palaeontologist, who made a series of discoveries near her home in Lyme Regis, Dorset.Continue reading... (Source: Guardian Unlimited Science)


Saturday 19 November 2022

Experts Issue New Guidelines For Lyme Disease Prevention

BOSTON (CBS) – After more than a decade, experts are issuing new guidelines for the prevention and treatment of Lyme disease. Even though many of the recommendations are geared toward medical professionals, there are some key takeaways for the general public. Namely, the best way to protect yourself is to wear protective clothing and insect repellent with DEET and do frequent tick checks if you’ve been outdoors. Bathing within two hours of an outdoor activity can reduce the risk of Lyme disease. And if you have pets, you should check them regularly for ticks to prevent the ticks from falling off and reattaching to humans. If you are bitten by a deer tick, it’s engorged, and it has been attached for 36 hours or more, you should call your doctor or get to an urgent care fac...


Saturday 19 November 2022

Long-term Lyme disease 'actually chronic fatigue syndrome'

Most people who think they have chronic Lyme disease are more likely to have chronic fatigue syndrome, say experts. (Source: BBC News | Health | UK Edition)


Saturday 19 November 2022

Boy, 17, died after Lyme disease infected his heart

Joseph Leone seemed to have a mild cold in the summer of 2013. A month later, he collapsed on the front lawn of his home in Poughkeepsie, New York. He died of Lyme disease that attacked his heart. (Source: the Mail online | Health)

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Saturday 19 November 2022

What Is Lyme Disease in Humans?

Title: What Is Lyme Disease in Humans?Category: Diseases and ConditionsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 2/12/2021 12:00:00 AM (Source: MedicineNet Arthritis General)


Saturday 19 November 2022

Doctors told this woman with Lyme disease to 'try meditation' and that she 'didn't look unwell'

Katherine Wood, 37, of Stow, Massachusetts, was bitten on a tick while on a nature walk in November 2016. Doctors dismissed her symptoms, until she was diagnosed with Lyme disease in July 2017. (Source: the Mail online | Health)


Saturday 19 November 2022

Lyme Vaccines Show New Promise, and Face Old Challenges Lyme Vaccines Show New Promise, and Face Old Challenges

The first human Lyme vaccine was pulled off the market nearly 20 years ago. A new effort faces lingering suspicions.Undark (Source: Medscape Allergy Headlines)


Saturday 19 November 2022

Breakthrough paves way for new Lyme disease treatment

(Virginia Tech) Virginia Tech biochemist Brandon Jutras has discovered the cellular component that contributes to Lyme arthritis, a debilitating and extremely painful condition that is the most common late stage symptom of Lyme disease. (Source: EurekAlert! - Infectious and Emerging Diseases)


Saturday 19 November 2022

Tick behavior and host choice explains geographical patterns of Lyme disease prevalence

(PLOS) A new analysis suggests that north-south differences in ticks' host choice, density, and host-seeking behaviors may explain why Lyme disease is more prevalent in the northeastern U.S. than in the southeast. Howard Ginsberg of the U.S. Geological Survey's Patuxent Wildlife Research Center and colleagues present these findings in an article publishing January 28th in the open-access journalPLOS Biology. (Source: EurekAlert! - Infectious and Emerging Diseases)


Saturday 19 November 2022

More than just Lyme Disease? Ceres Nanosciences pivots its sales strategy.

It got its start in developing a urine test for human growth hormones. But it hopes to go well beyond that now. (Source: bizjournals.com Health Care:Physician Practices headlines)


Saturday 19 November 2022

Lyme Testing Gets Fast and Easy Lyme Testing Gets Fast and Easy

Dr Paul Auwaerter comments on the newly approved, modified two-tier approach for diagnosing Lyme disease.Medscape Infectious Diseases (Source: Medscape Infectious Diseases Headlines)


Saturday 19 November 2022

How to treat wounds caused by insects and animal bites

  Being outdoors during the warm weather season carries with it the risk of bites of all kinds – insects, animals, ticks and others. Here is some helpful advice for treating bites and itching. Check the symptoms. Most insect bites and stings are mild, causing minor symptoms like itching, redness, stinging or a small degree of swelling around the bite. In some rare cases, stings from hornets, bees, wasps, scorpions or fire ants may lead to more serious reactions, including mosquito-borne West Nile virus. The Mayo Clinic advises moving away from the area where you were stung or bitten to prevent further injury. Then, try to remove the stinger if needed, and wash the wound with soap and water. For tick bites, remove the tick immediately. The Cleveland Clinic says the longer a tick...


Saturday 19 November 2022

New study identifies bird species that could spread ticks and Lyme disease

(Cary Institute of Ecosystem Studies) A new study published in the journalGlobal Ecology and Biogeography used machine learning to identify bird species with the potential to transmit the Lyme disease bacterium (Borrelia burgdorferi) to feeding ticks. The team developed a model that identified birds known to spread Lyme disease with 80% accuracy and flagged 21 new species that should be prioritized for surveillance. (Source: EurekAlert! - Medicine and Health)

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Saturday 19 November 2022

One-Of-A-Kind Lyme Disease Program At Spaulding In High Demand

BOSTON (CBS) — Looking back at baby pictures reminds Brandi Dean of a terrifying scare during her second pregnancy. It turns out the Wellesley mom had Lyme disease. “All of a sudden, the right side of my body was completely numb. My heart was racing. I was disoriented and I said, ‘I think you need to take me to the hospital,’” she remembered. After the standard antibiotic treatment, Dean still didn’t feel right. “I’d gone to 12 different specialists and they all had diagnosed me with anxiety.” She had what the Centers for Disease Control calls Post-Treatment Lyme Syndrome. She eventually found a doctor who understood her condition and recovered. Brandi Dean (WBZ-TV) Doctors don’t always know what causes the lingering symptoms, making the diagnosis controversial ...


Saturday 19 November 2022

Characteristics and patient pathways of Lyme disease patients: a retrospective analysis of hospital episode data in England and Wales (19982015)

Analysis (n=2361) noted significant increase (p (Source: Current Awareness Service for Health (CASH))


Saturday 19 November 2022

Mother left paralysed and blind after catching Lyme disease when she was bitten by a tick

Christine Jennings, 57, of Leicester, was bitten by an infected tick 25 years ago and her life has never been the same. The disease affected every part of her health leaving her barely holding on to life. (Source: the Mail online | Health)


Saturday 19 November 2022

Statue of fossil hunter Mary Anning to be erected after campaign

Crowdfunder led by schoolgirl raises £70,000 for sculpture of pioneering palaeontologist in Lyme Regis, DorsetA statue toMary Anning, a fossil hunter and palaeontologist once “lost to history” but now considered a significant female force in science, is finally to be erected after a crowdfunding campaign by a teenage girl.Evie Swire, 13, was nine years old when she first heard of Anning, who was born into a humble family in 1799 near Evie ’s Lyme Regis home in Dorset. The schoolgirl was outraged to discover there was no statue.Continue reading... (Source: Guardian Unlimited Science)


Saturday 19 November 2022

More Ticked Off - The Growing Threat of Lyme and Tick-Borne Diseases

With climate change, we are seeing more tick-borne diseases. Where is the funding to address this urgent crisis? (Source: Forbes.com Healthcare News)

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Saturday 19 November 2022

This New Approach May Reduce The Spread Of Lyme Disease

Finding an effective way to prevent the spread of tick-borne illness such as Lyme disease has been quite challenging over the past several decades. Researchers have now developed a new approach that goes right to the place where a tick transmits disease: its salivary glands. (Source: Forbes.com Healthcare News)

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Saturday 19 November 2022

Lyme disease: One major symptom that could mean you have Lyme disease

LYME disease is a relatively unknown condition with an estimated 2,000 to 3,000 new cases each year in England and Wales. For an unknown disease however, anyone can develop the condition as its caught by a tick. This major symptom could mean you might have Lyme disease. Do you have it? (Source: Daily Express - Health)


Saturday 19 November 2022

500K in U.S. diagnosed with Lyme disease annually, but some may not have it

Roughly 500,000 people across the United States are diagnosed with Lyme disease each year, according to new estimates released Wednesday by the CDC, but researchers raise concern that some people may be misdiagnosed. (Source: Health News - UPI.com)


Saturday 19 November 2022

Medical News Today: Lyme disease and rheumatoid arthritis: What you need to know

Lyme disease and rheumatoid arthritis are both conditions that can affect the nervous system and cause joint pain and swelling. Learn about their similarities and differences here. (Source: Health News from Medical News Today)


Saturday 19 November 2022

Developing New Guidelines on Lyme Disease

Public comments are still being accepted, but antibiotic treatment options for children are likely to be expanded to include the use of doxycycline. (Source: NYT Health)


Saturday 19 November 2022

Forget Sats – find a true measure of education | Letters

Clive Stafford Smithsays Sats are irrelevant to his son ’s life andMary Bousteddefends Labour ’s proposed assessment reforms, whileAnn MooreandRichard Wetherellhighlight the negative effects of testsAmanda Spielman may be warning the wrong people about exam anxiety, certainly as far as younger kids are concerned (Ofsted chief says teachers can cause ‘subliminal’ exam anxiety, May 14). My 10-year-old is not worried because I have told him Sats are irrelevant to his life. His secondary school will determine how best he will fit in, based on its own testing, when he gets there in September. I did ask him to do his best in sympathy with the people who are sweating it out this week: his excellent teachers, whose lives – and the rating of the school – depend on how he does at rote no...


Saturday 19 November 2022

Model predicts where Lyme disease-carrying ticks will develop

A new model helps identify areas with high populations of the ticks that carry Lyme disease, a study published Tuesday by the Proceedings of the Royal Society B found. (Source: Health News - UPI.com)


Saturday 19 November 2022

Lyme disease warning: Shocking symptoms of the disease - including this sign in your voice

LYME disease is still a relatively unknown disease with a myriad of symptoms which makes it difficult to detect. One such unusual symptom is that of losing your voice which left untreated could lead to vocal chord paralysis. (Source: Daily Express - Health)


Saturday 19 November 2022

Lyme disease more likely to affect older, wealthy white women

Disease most common in women aged 61 to 65 Related items fromOnMedica Not tackling infections in homeless could spark epidemics Concerns over UK young adults ’ readiness for first sex Malaria cases rise sharply Texting can improve flu jab uptake HPV programme linked to dramatic fall in cervical disease (Source: OnMedica Latest News)


Saturday 19 November 2022

South East corner of England is one of the worst areas in EUROPE for Lyme disease-carrying ticks

Researchers from across Europe, including the University of East London, mapped reports of the Lyme disease-causing Borrelia burgdorferi bacteria in ticks from 2010 to 2017. (Source: the Mail online | Health)

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Saturday 19 November 2022

Upstate to host virtual SUNY Lyme & Tick-borne Diseases Meeting Jan. 11, registration open to the public

The meeting will bring together researchers and scientists from across the SUNY system. (Source: SUNY Upstate Medical)


Saturday 19 November 2022

Lyme disease warning: The symptom you should watch out for after a tick bite - Dr Ranj

LYME DISEASE is a bacterial infection that affects up to 3,000 people in the UK every year. ITV This Morning ’s Dr Ranj has revealed the lyme disease signs and symptoms to watch out for, including a characteristic rash. Watch out for these symptoms are a tick bite. (Source: Daily Express - Health)


Saturday 19 November 2022

Lyme disease: Older white women 'at highest risk'

White older women in south-west England appear most likely to contract the disease, a study suggests. (Source: BBC News | Health | UK Edition)


Saturday 19 November 2022

Three-antibiotic cocktail clears 'persister' Lyme bacteria in mouse study

(Johns Hopkins University Bloomberg School of Public Health) A new study from researchers at the Johns Hopkins Bloomberg School of Public Health found that a slow-growing variant form of Lyme bacteria caused severe symptoms in a mouse model. The slow-growing variant form of Lyme bacteria, according to the researchers, may account for the persistent symptoms seen in ten to twenty percent of Lyme patients that are not cured by the current Lyme antibiotic treatment. (Source: EurekAlert! - Medicine and Health)


Saturday 19 November 2022

Fatal Lyme carditis in a 37-year-old man shows need for awareness of unusual symptoms

(Canadian Medical Association Journal) Physicians and the public should be aware of the different presentations of Lyme disease, as people spend more time outside in the warmer weather and as areas in Canada where the black legged tick is found expand. Three articles in CMAJ (Canadian Medical Association Journal), which describe a fatal case in a 37-year-old man, atypical skin lesions in a 56-year-old woman and severe neurological symptoms in a 4-year-old boy, illustrate the diversity in presentations. (Source: EurekAlert! - Medicine and Health)


Saturday 19 November 2022

Upstate to begin testing ticks from public on June 1

In 2019, the tick testing program, headed by Upstate Professor Saravanan Thangamani, PhD, received 1,921 tick samples from July through late October. About 25 percent of the ticks were found to carry Lyme disease. (Source: SUNY Upstate Medical)

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Saturday 19 November 2022

Rare Lyme disease-causing bacteria spotted on routine blood films

Eye on Innovation features exciting advances taking place at Mayo Clinic Laboratories. This monthly series shines a spotlight on recently developed tests and highlights how Mayo Clinic translates ideas and discoveries into testing resources that improve diagnosis and care for patients across the globe. ______________________________________________ It ’s long been known that Lyme disease is caused by bacteria transmitted through the bite of an infected black-legged tick (otherwise known as the deer tick). The understanding for many years was… (Source: News from Mayo Clinic)


Saturday 19 November 2022

Knowing Signs and Symptoms of Lyme Disease Is Critical for Early...

With America on lockdown the past two months, many people turned to the woods for safe isolation and social distancing. And now as sections of the country reopen and summer approaches, the outdoors...(PRWeb June 02, 2020)Read the full story at https://www.prweb.com/releases/knowing_signs_and_symptoms_of_lyme_disease_is_critical_for_early_detection_and_treatment_says_industry_leading_quidel/prweb17162063.htm (Source: PRWeb: Medical Pharmaceuticals)


Saturday 19 November 2022

Comparison of Lyme Disease in the United States and Europe Comparison of Lyme Disease in the United States and Europe

The clinical manifestations of this tickborne disease can differ according to the species causing the infection.Emerging Infectious Diseases (Source: Medscape Today Headlines)


Saturday 19 November 2022

National tick surveillance survey identifies gaps to be filled

(Cornell University) New Cornell-led research shows that inadequate funding is the main barrier to better surveillance and control of ticks, including the blacklegged tick, which spreads Lyme disease, the No. 1 vector-borne illness in the country. (Source: EurekAlert! - Biology)


Saturday 19 November 2022

Lyme Disease Tied to Higher Risk for Psychiatric Conditions, Suicide

TUESDAY, Aug. 17, 2021 -- Patients hospitalized with Lyme disease have a higher rate of mental disorders and attempted suicide after infection, according to a study published online July 28 in The American Journal of Psychiatry. Brian A. Fallon,... (Source: Drugs.com - Pharma News)

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Saturday 19 November 2022

What Are the Symptoms of Lyme Disease by Stages?

Title: What Are the Symptoms of Lyme Disease by Stages?Category: Diseases and ConditionsCreated: 6/17/2020 12:00:00 AMLast Editorial Review: 6/17/2020 12:00:00 AM (Source: MedicineNet Arthritis General)


Saturday 19 November 2022

Lyme Disease Can Wreak Havoc on Mental Health

(Source: The Doctors Lounge - Psychiatry)


Saturday 19 November 2022

In the Uncertainties of Lyme Testing, Lessons for COVID-19 In the Uncertainties of Lyme Testing, Lessons for COVID-19

The coronavirus testing debacle, much like early Lyme testing, is a reminder that diagnostics aren't perfect.Undark (Source: Medscape Medical News Headlines)


Saturday 19 November 2022

Lyme Disease, Mental Illness, Suicide

Lyme Disease May Up Risk for Mental Illness, Suicidal Behavior (Source: eMedicineHealth.com)


Saturday 19 November 2022

Study Confirms Memory, Concentration Issues After Lyme Disease

People who have been treated for Lyme disease, but continue to have symptoms, have changes in their brains that confirm the memory and concentration problems many of them have reported, a new study has found. (Source: WebMD Health)


Saturday 19 November 2022

Lyme Disease May Up Risk for Mental Illness, Suicidal Behavior Lyme Disease May Up Risk for Mental Illness, Suicidal Behavior

Increased inflammation, immune activation, and psychological factors may help explain the association of Lyme disease with higher rates of psychiatric disorders and suicidal behavior, researchers say.Medscape Medical News (Source: Medscape Medical News Headlines)


Saturday 19 November 2022

Co-infections in Persons With Early Lyme Disease Co-infections in Persons With Early Lyme Disease

Might some patients with early Lyme disease show evidence of co-infection with other tickborne pathogens?Emerging Infectious Diseases (Source: Medscape Today Headlines)


Saturday 19 November 2022

DR ELLIE CANNON: Could pills for Lyme disease actually be making it worse?

DR ELLIE CANNON: There are between 2,000 and 3,000 cases of Lyme disease every year in England and Wales - with areas such as the New Forest and Scottish Highlands the highest risk. (Source: the Mail online | Health)

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Saturday 19 November 2022

Lyme Disease Now a Threat in City Parks

WEDNESDAY, May 15, 2019 -- As deer populations have exploded across America, moving from forests to suburbs to urban parks, they have brought the threat of Lyme disease to millions of city dwellers, a new study finds. In fact, the deer tick that... (Source: Drugs.com - Daily MedNews)


Saturday 19 November 2022

Can Breakthrough Infections Lead to Long COVID? For an Unlucky Few, Yes

When health experts talk about the remarkable efficacy of COVID-19 vaccines, they typically point to their ability to prevent severe disease and death. Fully vaccinated people can still get “breakthrough” infections from the virus that causes COVID-19—but compared to an unvaccinated person, they’re more than 10 times less likely to be hospitalized or die from their illness, according to U.S. Centers for Disease Control and Prevention (CDC) research. Officials often point to these impressive figures as evidence that we can tame COVID-19 into a mostly mild illness that behaves like a routine cold or flu, and thus with which we can coexist. After all, the vaccines were not designed to quash viral spread entirely; they were designed to defang the virus by preventing its...


Saturday 19 November 2022

Consumer Health: Do you know what to do if you find a tick?

Tick bites: First aid Most tick bites are painless and cause only minor symptoms, such as redness, swelling or a sore on the skin. But some ticks transmit bacteria that cause illnesses, including Lyme disease and Rocky Mountain spotted fever. Learn the correct way to remove and handle a tick, and when you need to [...] (Source: News from Mayo Clinic)


Saturday 19 November 2022

Black patients ’ Lyme disease often diagnosed late, possibly due to missed signs

FINDINGSA UCLA study suggests that many physicians may not have the knowledge or training to properly recognize how Lyme disease appears on the skin of Black patients. The disease, caused by the tick-borne Borrelia bacterium, generally begins with a bull ’s-eye–shaped rash on the skin, along with fever, headache, chills and muscle pain; if not diagnosed promptly and treated with antibiotics, it can lead to more severe and long-lasting symptoms.UCLA ’s Dr. Dan Ly found that approximately 1 in 3 Black patients who were newly diagnosed with Lyme disease already had related neurological complications such as meningitis, neuropathy and cranial neuritis — an indication that the disease may not have been properly diagnosed in its earlier stages. Less than 1 in 10 newly diagnosed white pat...


Saturday 19 November 2022

What Causes Facial Nerve Palsy?

Discussion Facial nerve palsy has been known for centuries, but in 1821 unilateral facial nerve paralysis was described by Sir Charles Bell. Bell’s palsy (BP) is a unilateral, acute facial paralysis that is clinically diagnosed after other etiologies have been excluded by appropriate history, physical examination and/or laboratory testing or imaging. Symptoms include abnormal movement of facial nerve. It can be associated with changes in facial sensation, hearing, taste or excessive tearing. The right and left sides are equally affected but bilateral BP is rare (0.3%). Paralysis can be complete or incomplete at presentation. All ages can be affected but there are increased risks in the 15-45 year age group and those with diabetes, immunodeficiency or are pregnant. Etiology is specif...


Saturday 19 November 2022

Global Lyme Alliance Congratulates Dr. Kim Lewis on Groundbreaking...

An exciting new finding by. Dr. Kim Lewis of Northeastern University gives hope that Lyme disease can be potentially treated without harming the microbiome.(PRWeb October 07, 2021)Read the full story at https://www.prweb.com/releases/global_lyme_alliance_congratulates_dr_kim_lewis_on_groundbreaking_publication_a_selective_antibiotic_for_lyme_disease/prweb18247374.htm (Source: PRWeb: Medical Pharmaceuticals)


Saturday 19 November 2022

Dangerous ticks are on the rise. Here's what you need to know.

There are new concerns about previously-rare types of tick-borne diseases being seen more frequently in the United States. The blacklegged tick not only spreads Lyme disease, it can also transmit a serious virus that may have killed one man and made another sick in New Jersey. In Kentucky, a two-year-old boy is reportedly recovering from another tick-borne disease, Rocky Mountain spotted fever. Dr. David Agus joins "CBS This Morning" from Los Angeles to discuss how to protect yourself from ticks, how to remove them and the consequences of some tick-borne diseases. (Source: Health News: CBSNews.com)

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Saturday 19 November 2022

Judge Dismisses Lyme Disease Lawsuit Against IDSA, Doctors Judge Dismisses Lyme Disease Lawsuit Against IDSA, Doctors

The Infectious Diseases Society of America (IDSA) could have chosen to settle the lawsuit instead of fighting it, but the principles at stake were too high, they decided.Medscape Medical News (Source: Medscape Rheumatology Headlines)


Saturday 19 November 2022

Lyme disease has 'dominated' my life

Morven-May MacCallum speaks out as GPs are urged to be vigilant about the infection spread by ticks. (Source: BBC News | Health | UK Edition)

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Saturday 19 November 2022

What It ’s Like to Live with Lyme Disease

WebMD sat down with New York Times columnist Ross Douthat to find out a little bit more about his journey and what he recommends to anyone with Lyme Disease. (Source: WebMD Health)

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Saturday 19 November 2022

A bacterial remnant may explain arthritis in Lyme patients

New Yale research offers insight into why some Lyme disease patients continue to suffer from debilitating arthritis even after antibiotic treatment. (Source: Yale Science and Health News)


Saturday 19 November 2022

A targeted antibiotic for treating Lyme disease

Researchers found that a neglected antibiotic called hygromycin A selectively kills the bacteria that cause Lyme disease. (Source: NIH Research Matters from the National Institutes of Health (NIH))


Saturday 19 November 2022

New York Times' Story On Lyme Misses The Bull's Eye

This week's NYTimes did a disservice to readers by minimizing the severity of Lyme disease. Here's why. (Source: Forbes.com Healthcare News)


Saturday 19 November 2022

Effects of COVID-19 Pandemic on Reported Lyme Disease Effects of COVID-19 Pandemic on Reported Lyme Disease

Did spending more time indoors during the COVID-19 pandemic result in fewer reported cases of Lyme disease?Emerging Infectious Diseases (Source: Medscape Today Headlines)


Saturday 19 November 2022

Bull ’s eye rash — sufficient sign to treat for Lyme disease

Lab tests not needed if rash is present, says NICE Related items fromOnMedica TB could be cured by four months ’ treatment in many patients Antibiotics courses often longer than guidelines Doctors call for StrepB screening in late pregnancy JCVI recommends universal HPV vaccination New ‘treadmill test’ can predict mortality (Source: OnMedica Latest News)


Saturday 19 November 2022

Novel Lyme vaccine shows promise

A Yale-developed vaccine that helps more quickly identify tick bites on guinea pigs could offer humans protection against Lyme Disease and other pathogens. (Source: Yale Science and Health News)


Saturday 19 November 2022

Woman whose Lyme disease makes her feel 'like she has dementia' is raising £6,000 for treatment

Clare Haworth, from North Lanarkshire, first became ill six years ago but doesn't remember ever being bitten by a tick, which is how people catch Lyme disease. (Source: the Mail online | Health)


Saturday 19 November 2022

Scientists Step Closer to Vaccine for Tick Bites

NIH researcher Andaleeb Sajid discusses her study ’s finding that ticks were unable to feed on vaccinated guinea pigs, preventing transmission of the pathogen that causes Lyme disease. (Source: The Scientist)


Saturday 19 November 2022

Lyme Disease: 5 Characteristics of the Ideal Test

The ideal test for Lyme disease needs to be direct and highly sensitive in specific areas of detection. A new review highlights the 5 key criteria. (Source: ConsultantLive)

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Saturday 19 November 2022

What Does Lyme Disease Do to a Person

? (Source: eMedicineHealth.com)

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Saturday 19 November 2022

Devastated parents fear Lyme disease killed their 39-year-old daughter

Carly Ellis, from Gloucester, was diagnosed with the infection in 2011, with doctors saying a two-week course of antibiotics would 'clear' her. (Source: the Mail online | Health)


Saturday 19 November 2022

Lyme disease: Man spent £25,000 before getting diagnosis

Steven Williams, 36, said his fit, active life was "totally devastated" by the struggle for answers. (Source: BBC News | Health | UK Edition)


Saturday 19 November 2022

Drug-resistant superbugs spreading in European hospitals

Research has found strains of Klebsiella pneumoniae resistant to the carbapenems spreading through hospitals Related items fromOnMedica GPs given help to spot Lyme disease Single-dose malaria drug eliminates parasite from liver Antibiotic research programme launched Measles cases triple in Europe but immunisation rates grow Chief medical officer launches push for flu jab drive (Source: OnMedica Latest News)


Saturday 19 November 2022

Lyme disease: Maesteg patient spent £25k getting diagnosed

Steven Williams was left bedridden and shaking for 18 hours a day after contracting the illness. (Source: BBC News | Health | UK Edition)


Saturday 19 November 2022

Estimated U.K. Incidence Rate of Lyme Disease 12.1 per 100,000

WEDNESDAY, July 31, 2019 -- The incidence of Lyme disease (LD) increased from 2001 to 2012 in the United Kingdom, with an estimated incidence rate of 12.1 per 100,000 individuals per year, according to a study published online July 30 in BMJ... (Source: Drugs.com - Pharma News)


Saturday 19 November 2022

Long COVID Patients Are Waiting Months for Care, and the Problem May Only Get Worse

In March 2020, Laura Fitton, a 50-year-old entrepreneur in Massachusetts, had a high fever, sore throat, gastrointestinal issues, and loss of taste. But at the time, few of those symptoms were linked to COVID-19, so Fitton wasn’t eligible for a test. It took seven more months of persistent symptoms—including brain fog, swollen joints, fast heart rate, chills, and fatigue—for a doctor to order an antibody test. Although the test came back negative—perhaps because of how much time had passed since she had gotten sick—Fitton was relieved that a doctor was finally exploring the possibility of Long COVID, a little-understood condition in which people suffer symptoms long after their acute infection passes. [time-brightcove not-tgx=”true”] Two years afte...


Saturday 19 November 2022

UK tick-borne Lyme disease cases higher than previous estimates

Cases of a nasty infection passed on through tick bites may be much higher in the UK than previously thought, according to new research. (Source: Nursing Times)


Saturday 19 November 2022

Valneva and Pfizer report further positive Phase 2 data for Lyme disease vaccine candidate

Valneva SE (Nasdaq: VALN; Euronext Paris: VLA), a specialty vaccine company, and Pfizer Inc. (NYSE: PFE) today reported further positive Phase 2 data for their Lyme disease vaccine candidate, VLA15. Based on these new results, Valneva and Pfizer plan to proceed with a three-dose primary series vaccination schedule in a planned Phase 3 clinical trial. (Source: World Pharma News)


Saturday 19 November 2022

The Lyme Wars: Major Organizations Aren't Playing Nicely Together

Several groups have differing guidelines for diagnosing and treating Lyme. Too much is in dispute, since our knowledge is so limited. (Source: Forbes.com Healthcare News)

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Saturday 19 November 2022

Aaron Bell: Tory MP confirms PM no confidence letter

Newcastle-under-Lyme MP Aaron Bell says a "breach of trust" has made the PM's position "untenable". #tory #newcastleunderlyme #confidenceletter #aaronbell (Source: Reuters: Health)

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Saturday 19 November 2022

Lyme disease: If left untreated, you could experience these ‘serious’ symptoms

LYME DISEASE is a tick-borne infectious disease. Initial symptoms are usually mild, but if left untreated, more serious symptoms may reveal themselves. Have you spotted these serious signs? (Source: Daily Express - Health)


Saturday 19 November 2022

Lyme and Other Tick-Borne Diseases Are on the Rise. But Why? Lyme and Other Tick-Borne Diseases Are on the Rise. But Why?

The complex interplay of ticks, their habitats and hosts — along with changes in land use and climate — may be enabling the spread of the pathogens they carry.Knowable Magazine (Source: Medscape Infectious Diseases Headlines)


Saturday 19 November 2022

White 'rich' women may be 'more likely to have Lyme disease'

Scientists from the National Institute for Health Research in London analysed 2,361 patients who were admitted to hospital with the bacterial infection between 1998 and 2015. (Source: the Mail online | Health)


Saturday 19 November 2022

Could gene-edited ticks make Lyme disease an ailment of the past?

US researchers, who identified the gene editing method, said it could enable them to alter parts of a tick's DNA used to carry and transmit bacteria that causes diseases. (Source: the Mail online | Health)


Saturday 19 November 2022

Recommendations Developed for Management of Lyme Disease

FRIDAY, Aug. 16, 2019 -- The Infectious Diseases Society of America, the American Academy of Neurology, and the American College of Rheumatology have released a draft of their joint clinical practice guidelines for the management of Lyme... (Source: Drugs.com - Pharma News)


Saturday 19 November 2022

DR ELLIE CANNON: I've felt dizzy for over three years. Is it Lyme disease?

DR ELLIE CANNON: It is true Lyme disease can cause neurological problems, including dizziness and feeling off-balance, but it's rare for such symptoms to be the only complaint. (Source: the Mail online | Health)


Saturday 19 November 2022

Distressing video shows a father, 34, writhing in agony after he caught Lyme disease five years ago

John St Julien, now 34, moved to east Africa in 2014 to launch a charity helping local children be educated. He soon started to feel run down but dismissed it as the pressure of his job. (Source: the Mail online | Health)


Saturday 19 November 2022

Targeting Ticks and Lyme Disease With Gene Editing

Ticks have evaded gene editing attempts for years, but scientists have finally figured out how to effectively modify their genome as they work to reduce disease transmission. (Source: WebMD Health)


Saturday 19 November 2022

The Week That Wasn't: Reverse Aging, Lyme Test, Apple Health Studies The Week That Wasn't: Reverse Aging, Lyme Test, Apple Health Studies

Three medical stories that we didn't cover, explained.Medscape (Source: Medscape Allergy Headlines)

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Saturday 19 November 2022

Targeting Ticks and Lyme Disease With Gene Editing Targeting Ticks and Lyme Disease With Gene Editing

Ticks have evaded gene editing attempts for years, but scientists have finally figured out how to effectively modify their genome as they work to reduce disease transmission.WebMD Health News (Source: Medscape Infectious Diseases Headlines)

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Saturday 19 November 2022

NIH sets five-year plan for tickborne disease research

With an increase of nearly 10,000 cases of tickborne disease from 2016 to 2017 -- mostly lyme disease -- the National Institutes of Health announced a five-year plan to expand research and reduce infections. (Source: Health News - UPI.com)


Saturday 19 November 2022

Researchers Are Getting Closer to Understanding Long COVID. But Treatments Are Likely Still a Ways Off

Two years into the COVID-19 pandemic, questions about Long COVID still outnumber answers. Why do some people develop long-lasting symptoms—often after a mild case of COVID-19, sometimes even after being vaccinated—while others fully recover from their brushes with the SARS-CoV-2 virus? Why does Long COVID seem to disproportionately appear in women? How can one condition affect numerous bodily systems, causing symptoms ranging from brain fog to joint pain to total exhaustion? Is Long COVID a single diagnosis, or is it better understood as an umbrella term for a spectrum of disease, caused by a range of biologically diverse effects of the virus? Or, could it actually be a new manifestation of post-viral illnesses that have been around for decades? [time-brightcove not-tgx=”...


Saturday 19 November 2022

Lyme disease: Feeling this sensation in your head could be a warning sign of the condition

LYME disease is a bacterial infection spread to humans by infected ticks. Ticks are tiny spider-like creatures found in woodland and heath areas. They feed on the blood of birds, mammals and humans. Feeling this sensation in your head could mean you have Lyme disease. (Source: Daily Express - Health)


Saturday 19 November 2022

Upstate tick experts predicts huge season for ticks

The number of ticks sent to the Upstate lab as part of its citizen science program has skyrocketed with more than 30 percent found to be carrying Lyme disease. (Source: SUNY Upstate Medical)


Saturday 19 November 2022

Tick-born encephalitis virus detected in ticks in UK

First ever cases in Britain, says Public Health England Related items fromOnMedica Vaccine linked to earlier onset of seizures in Dravet syndrome Scans show severe brain damage in Zika-affected babies Lyme disease may be three times more common in UK than previously thought Single-dose malaria drug eliminates parasite from liver Common anti-parasitic could be new tool for malaria control (Source: OnMedica Latest News)


Saturday 19 November 2022

Upstate tick expert predicts huge season for ticks

The number of ticks sent to the Upstate lab as part of its citizen science program has skyrocketed with more than 30 percent found to be carrying Lyme disease. (Source: SUNY Upstate Medical)


Saturday 19 November 2022

Medical News Today: Chronic Lyme disease: Everything you need to know

Chronic Lyme disease occurs when a person who has already received treatment for Lyme disease continues to have symptoms in the long term. Learn more about this condition here. (Source: Health News from Medical News Today)


Saturday 19 November 2022

Ben Stiller health: Star's 'arthritic' Lyme disease symptoms - 'it's a really tough thing'

ACTOR Ben Stiller, who starred in classics like Night at the Museum and Meet the Fockers was diagnosed with Lyme disease. The star underwent lots of tests before he finally discovered the reality of his situation. (Source: Daily Express - Health)


Saturday 19 November 2022

Lone Star Ticks Expanding Range Into Northeast, Report Says

(CNN/CBS) — The climate crisis is making us more vulnerable to ticks in an unprecedented and growing threat to public health, according to a new report. Bacterial and protozoan tick-borne diseases doubled in the United States between 2004 and 2016, the report notes, and in 2017, more than 90% of the 60,000 vector-borne diseases in the United States were linked to these particular bloodsucking bugs. The warmer temperatures brought by the climate crisis, in addition to ecological changes and reforestation, have extended the bugs’ range into regions that had not seen certain types of ticks for many decades, if ever. And the report published in the New England Journal of Medicine Tuesday warns that we should be “bracing for the worst.” The lone star tick, a tick disting...

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Saturday 19 November 2022

Alec Baldwin said his family ‘live in fear’ after he was ‘attacked’ by Lyme disease

ALEC BALDWIN, 64, said his family "live in fear" of Lyme disease after the star was "attacked" by the condition for two decades. (Source: Daily Express - Health)

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Saturday 19 November 2022

Hopes rise for statue of pioneering fossil hunter Mary Anning

Mother ’s fundraising campaign in Lyme Regis has been backed by likes of David AttenboroughEvie Swire was nine years old when she first heard the story of a woman who had lived near her home in Dorset and, in her own way, changed the world.Mary Anning was born into a humble family in Lyme Regis in 1799 and grew up hunting for fossils in the area ’s cliffs to supplement their meagre income. When she was 12, she and her brother discovered one of the first ichthyosaurus skeletons, and she would go on to make many other pioneering finds and become immensely knowledgeable in the emerging field of palaeontology.Continue reading... (Source: Guardian Unlimited Science)


Saturday 19 November 2022

Novel Antibody Response Test May Aid in Lyme Disease Diagnostics, Detect Recurrence Novel Antibody Response Test May Aid in Lyme Disease Diagnostics, Detect Recurrence

A test that detects antiphospholipid antibodies in the blood of Lyme disease patients shows potential for identifying the disease sooner than current methods and possibly tracking response to therapy and recurrence, researchers say.Reuters Health Information (Source: Medscape Pathology Headlines)


Saturday 19 November 2022

What is Lyme disease? Things you should know

Lyme disease is the most common illness spread by ticks in North America and Europe. View Lyme disease symptoms, treatments and prevention tips. (Source: CNN.com - Health)


Saturday 19 November 2022

What Is Chronic Lyme Disease (Stage 3)?

Title: What Is Chronic Lyme Disease (Stage 3)?Category: Diseases and ConditionsCreated: 6/17/2020 12:00:00 AMLast Editorial Review: 4/8/2022 12:00:00 AM (Source: MedicineNet Arthritis General)


Saturday 19 November 2022

Justin Bieber Reveals He Has Lyme Disease

Singer Justin Bieber says he has Lyme disease, revealing his condition Wednesday in an Instagram post addressing comments people have made about his appearance in recent months. (Source: WebMD Health)


Saturday 19 November 2022

Tick Spraying May Not Guard Against Lyme Disease

Common measures to kill the harmful pests appear to protect pets more than people, researchers say. (Source: WebMD Health)


Saturday 19 November 2022

Lyme disease patient almost suffered a ruptured artery from same illness as Justin Bieber

The pensioner, from Castelo Branco, Portugal, went to hospital with excruciating pains in his chest and extremely low blood pressure. Justin Bieber announced he had the illness last week. (Source: the Mail online | Health)


Saturday 19 November 2022

What is Vocal Cord Dysfunction?

Discussion Vocal cord function involves balancing muscular and neuronal functions. The superior laryngeal nerves (SLN) and recurrent laryngeal nerves (RLN) are the main nerves responsible for sensation and motor innervation. There are two sides to the larynx and they operate ipsilaterally, therefore one side can be affected while the other is not. Vocal cord paresis or paralysis are “an impairment of the vocal fold motor function that is caused by nerve or neuromuscular abnormalit[ies].” Paresis involves some maintenance of vocal cord movement while paralysis does not. Paresis is also more of a continuum than an absolute movement or not. “Paresis is often considered idiopathic, but potentially any pathology present from skull base to mediastinum that compresses, tethers, ...


Saturday 19 November 2022

Portable Lab You Plug into Your Phone can Diagnose Illnesses Like Coronavirus

Engineers with the University of Cincinnati have created a tiny portable lab that plugs into your phone, connecting it automatically to a doctor's office through a custom app UC developed. The lab the size of a credit card can diagnose infectious diseases such as coronavirus, malaria, HIV or Lyme disease or countless other health conditions like depression and anxiety. (Source: eHealth News EU)


Saturday 19 November 2022

Tim Kaine Refuses to Let Long COVID Be an Afterthought

When Virginia Sen. Tim Kaine came down with a “blizzard” of allergy-like symptoms in March 2020, he blamed the layer of pollen coating his car. “It was Washington, D.C., in late March,” he says. I thought, “‘Okay, well, this is hay fever gone wild.’” Only when his wife, Anne Holton, developed “textbook” COVID-19 symptoms did Kaine start to wonder if he might have the new virus, the subject of the massive economic assistance bill—the CARES Act—that he and other lawmakers were then working to pass. Testing at that time was hard to come by, even for Hillary Clinton’s 2016 running mate, but antibody tests later revealed that Kaine and Holton had been infected by the virus that causes COVID-19. [time-brightcove not-t...

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Saturday 19 November 2022

Ethnobotanical medicine is effective against the bacterium causing Lyme disease

(Frontiers) A preclinical in vitro study shows that selected plant-based herbal medicines, especially Ghanaian quinine and Japanese knotweed, work better than antibiotics against the bacterium that causes Lyme disease. These findings represent an important step towards the development of treatments that might be better tolerated and more effective than the current standard of care. (Source: EurekAlert! - Infectious and Emerging Diseases)

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Saturday 19 November 2022

GPs urged to spot the early signs of Lyme disease

GPs are failing to spot the early signs of Lyme disease, an infection spread through tick bites that is on the rise in the UK, experts warn. Early diagnosis allows treatment with anti-biotics. (Source: the Mail online | Health)


Saturday 19 November 2022

Many lyme disease cases go unreported; A new model could help change that

(Columbia University) A new model based on 17 years of data can help predict the trajectory of where Lyme disease will spread. Identifying high-risk areas can lead to surveillance in counties and areas where infections are likely to emerge. It also allows authorities to alert physicians and the public, which can lead to early treatment, when it is most effective. (Source: EurekAlert! - Medicine and Health)


Saturday 19 November 2022

Lyme Disease May Cost US Nearly $970 Million per Year Lyme Disease May Cost US Nearly $970 Million per Year

Patients with localized disease had the lowest attributed costs, highlighting the importance of early diagnosis and intervention.Medscape Medical News (Source: Medscape Medical News Headlines)


Saturday 19 November 2022

White Supremacists, Yellow Peril & “Chinese Virus” Add to a Volatile Political Mix

Credit: United Nations By Thalif DeenUNITED NATIONS, Mar 24 2020 (IPS) When US President Donald Trump repeatedly characterized the fast-spreading COVID-19 as a “Chinese virus” last week, it prompted some white supremacists to resurrect an age old ethnic slur against Chinese and East Asians: the “Yellow Peril” which, in a bygone era, was touted as a xenophobic threat to the Western world. But Tendayi Achiume, UN Special Rapporteur on Contemporary Forms of Racism, Racial Discrimination and Xenophobia, is highly critical of the racist interpretation to a disease which has claimed over 16,500 deaths worldwide and accounted for more than 378,000 infections, with the epicenter shifting from China to Europe. Singling out Trump, she said: it’s dismaying, however, “to witness State off...


Saturday 19 November 2022

The Tick That Causes a Meat Allergy Is on the Move

The lone star tick can trigger an allergic reaction to red meat in those bitten. Now this arachnid ’s territory is expanding. (Source: NYT Health)


Saturday 19 November 2022

Fears of Unregulated ‘Wild West’ as COVID-19 Blood Tests Hit the U.S. Market

WASHINGTON — Blood tests for the coronavirus could play a key role in deciding whether millions of Americans can safely return to work and school. But public health officials warn that the current “Wild West” of unregulated tests is creating confusion that could ultimately slow the path to recovery. More than 70 companies have signed up to sell so-called antibody tests in recent weeks, according to U.S. regulators. Governments around the world hope that the rapid tests, which typically use a finger-prick of blood on a test strip, could soon ease public restrictions by identifying people who have previously had the virus and have developed some immunity to it. But key questions remain: How accurate are the tests, how much protection is needed and how long will that protec...


Saturday 19 November 2022

Lyme disease symptoms: The signs you need to look out for as UK set to see warmer weather

LYME disease is a type of bacterial infection spread to humans from infected ticks. While not much of a problem during the winter, Lyme disease can be a danger during the summer. As a result, it's important to be wary of the symptoms to look out for. (Source: Daily Express - Health)


Saturday 19 November 2022

Virginia Tech researcher receives grant to study Lyme arthritis

(Virginia Tech) With a $661,216 grant from the Steven& Alexandra Cohen Foundation, Brandon Jutras, an assistant professor of biochemistry in the Virginia Tech College of Agriculture and Life Sciences, will study Lyme arthritis, including the cellular component that contributes to it. (Source: EurekAlert! - Infectious and Emerging Diseases)


Saturday 19 November 2022

Expert warns that the prevalence of ticks in America is growing

Americans can avoid contracting Lyme disease, if they take a few simple steps. The steps include regular tick checks, wearing long sleeves in areas of high exposure and using bug spray. (Source: the Mail online | Health)

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Saturday 19 November 2022

Swelling of the Ear Lobe As a Manifestation of Lyme Disease Swelling of the Ear Lobe As a Manifestation of Lyme Disease

This case describes an unusual dermatologic presentation of Lyme disease, borrelial lymphocytoma, which is rare in the US but more common in Europe.Journal of Medical Case Reports (Source: Medscape Today Headlines)


Saturday 19 November 2022

Statue of fossil-hunting pioneer Mary Anning to be unveiled in Dorset

A nine-year-old pointed out what was missing in Lyme Regis. Her long campaign has now borne fruitIt all began with a curious nine-year-old and a question that she asked her mother. Where in their hometown of Lyme Regis was the statue ofMary Anning, the pioneering Victorian fossil hunter who, she had recently discovered, had lived and worked there?There wasn ’t one, Anya Pearson was forced to tell her indignant daughter. Anning’s lifetime of discoveries – including finding the first ichthyosaur skeleton at the age of just 12 – may have profoundly shaped the emerging science of palaeontology, but in her own Dorset town and farther afield, she had been largely forgotten.Continue reading... (Source: Guardian Unlimited Science)


Saturday 19 November 2022

Tick surveillance and control lagging in US, study shows

(Entomological Society of America) While the prevalence of Lyme disease and other illnesses spread by ticks has steadily increased in the United States over the past 20 years, a new study of the state of American tick surveillance and control reveals an inconsistent and often under-supported patchwork of programs across the country. (Source: EurekAlert! - Infectious and Emerging Diseases)

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Saturday 19 November 2022

'Outdoorsy' Father-of-two, 60, left suffering memory problems with Lyme disease

Russell Bell, 65, from Raleigh in North Carolina, was only diagnosed with the tick-borne disease after he went for tests nine months after developing symptoms. He died earlier this year. (Source: the Mail online | Health)


Saturday 19 November 2022

What Causes Bradycardia?

Discussion Bradycardia is a heart rate below what the lowest value that is normal for age. Infants and children have higher heart rates that slowly decrease with age to adult levels. It is usually noted as an incidental finding because of increased vagal tone. Reasons for cardiology referral include associated heart murmur, syncope especially if associated with exercise or unusual triggers, other signs such as chest pain or palpitations, family history of sudden cardiac death, congenital heart disease or familial heart disease, bradycardic medication use, or unusual symptoms associated with the concern. Severe bradycardia that causes poor cardiac output is a medical emergency. Fortunately most children have mild bradycardia which may have no symptoms or can manifest as dizziness, syncope, ...


Saturday 19 November 2022

'Outdoorsy' Father-of-two, 65, left suffering memory problems with Lyme disease

Russell Bell, 65, from Raleigh in North Carolina, was only diagnosed with the tick-borne disease after he went for tests nine months after developing symptoms. He died earlier this year. (Source: the Mail online | Health)


Saturday 19 November 2022

Erythema - red flag symptoms

Dr Tillmann Jacobi considers red flag symptoms in erythema and details three of the most common causes; Lyme disease, erythema infectiosum and erythema multiforme. (Source: GP Online Education)


Saturday 19 November 2022

Farmers at High Risk of Tick-Borne Illness, But Awareness Lacking

TUESDAY, June 7, 2022 -- American farmers are at increased risk for tick bites, but new research shows they are doing little to defend themselves against the insects and the illnesses they cause. Tick-borne diseases include Lyme disease, Rocky... (Source: Drugs.com - Daily MedNews)


Saturday 19 November 2022

Antibiotic alternative shows promise

UK researchers discover new compound which kills antibiotic-resistant superbugs Related items fromOnMedica GPs given help to spot Lyme disease Single-dose malaria drug eliminates parasite from liver TB could be cured by four months ’ treatment in many patients Antibiotics courses often longer than guidelines 'Keep Antibiotics Working' campaign resurfaces (Source: OnMedica Latest News)


Saturday 19 November 2022

Why So Many Long COVID Patients Are Reporting Suicidal Thoughts

Last year, Diana Berrent—the founder of Survivor Corps, a Long COVID support group—asked the group’s members if they’d ever had thoughts of suicide since developing Long COVID. About 18% of people who responded said they had, a number much higher than the 4% of the general U.S. adult population that has experienced recent suicidal thoughts. A few weeks ago, Berrent posed the same question to current members of her group. This time, of the nearly 200 people who responded, 45% said they’d contemplated suicide. While her poll was small and informal, the results point to a serious problem. “People are suffering in a way that I don’t think the general public understands,” Berrent says. “Not only are people mourning the life that they thought...

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Saturday 19 November 2022

Tick-borne diseases are on the rise. Here's what you need to know.

The tick that carries Lyme can also transmit the rare but serious powassan virus believed to have killed one man and sickened another in New Jersey (Source: Health News: CBSNews.com)


Saturday 19 November 2022

Nearly 15 PER CENT of world has Lyme disease, according to first global estimate

Researchers from China, who examined blood sample data from studies involving more than 150,000 people, found 14.5 per cent had Lyme disease. (Source: the Mail online | Health)


Saturday 19 November 2022

My Son Got Lyme Disease. He ’s Totally Fine.

Horror stories about lingering Lyme disease proliferate, but the illness is easily treated. (Source: NYT Health)


Saturday 19 November 2022

Mayo Clinic expert speaks of significance of Lyme disease uptick

Lyme disease has infected more than 14% of the world's population, according to a new study. "It's significant," says Dr. Bobbi Pritt, director of the Clinical Parasitology Laboratory at Mayo Clinic. "If you look at the numbers and how it breaks down in regions across the United States, in some areas, that exceeds 50% seropositivity. That means people are walking around with antibodies in their blood that are detectable. That shows they've been exposed to Lyme disease at some… (Source: News from Mayo Clinic)


Saturday 19 November 2022

Lyme disease quality standard (QS186)

This quality standard covers diagnosing and managing Lyme disease in people of all ages. It also includes raising public awareness about prevention. It describes high-quality care in priority areas for improvement. It was published in July 2019. (Source: Current Awareness Service for Health (CASH))


Saturday 19 November 2022

Global Seroprevalence of Tickborne Lyme Disease About 14.5 Percent

TUESDAY, June 14, 2022 -- The reported estimated global seroprevalence of Borrelia burgdorferi sensu lato (Bb) is 14.5 percent, according to a systematic review and meta-analysis published online June 13 in BMJ Global Health. Yan Dong, from the... (Source: Drugs.com - Pharma News)


Saturday 19 November 2022

Maine Confirmed Its First Case of a Rare Tick-Borne Virus in Years. Here ’s What to Know About Powassan

Health officials have confirmed that an individual in Maine is sick with Powassan virus disease, marking the first time since 2017 that a person in the state has come down with the rare and serious tick-borne illness. The Maine Center for Disease Control and Prevention announced Wednesday that a southern Maine resident was hospitalized for Powassan encephalitis—brain inflammation associated with the virus—after showing symptoms in late June. The announcement did not specify the individual’s current condition, but health officils doctors to stay vigilant about the potential spread of Powassan throughout the summer and early fall. Here’s what to know about the tick-borne Powassan virus disease. What is Powassan virus disease? Like Lyme disease, Powassan is spread by ...


Saturday 19 November 2022

Nearly 15% of People Worldwide Have Had Lyme Disease, Study Says

Lyme disease was first named nearly 50 years ago in Lyme, Connecticut, but the tick-borne disease is now found around the world. A new study published in BMJ Global Health estimates that 14.5% of the world’s population has, at some point, been infected with Lyme disease, which can cause short-term symptoms including a skin rash, fever, headache, and fatigue—as well as long-term ones, including damage to the joints, heart, and nervous system. The scourge also appears to be getting worse. Lyme prevalence has doubled from 2010 to 2021, compared to 2001 to 2010. [time-brightcove not-tgx=”true”] The study, led by a team of researchers from the Institute for Tropical Medicine at Kunming Medical University in China, was a meta-analysis of 89 studies dating as far back as ...


Saturday 19 November 2022

FDA OKs Streamlined Lyme Disease Tests to Aid Earlier Diagnosis FDA OKs Streamlined Lyme Disease Tests to Aid Earlier Diagnosis

The modified approach for detecting exposure to Borrelia burgdorferi uses two enzyme immunoassays, with no need for Western blot.FDA Approvals (Source: Medscape Emergency Medicine Headlines)

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Saturday 19 November 2022

It's Lyme Time It's Lyme Time

Lyme prevalence is increasing. Are we paying attention?Medscape (Source: Medscape Today Headlines)

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Saturday 19 November 2022

Incidence of Lyme disease in the UK: a population-based cohort study

UK cohort study (n=8.4 million) found that the number of cases of Lyme disease has increased rapidly since 2001, resulting in an incidence of 12.1 per 100,000 per year in 2012. Authors state that this should lead to increased awareness and the need for preventative measures. (Source: Current Awareness Service for Health (CASH))


Saturday 19 November 2022

Nearly 10% of people in North America have had the deadly tick-borne illness Lyme disease

Scientists in southern China estimated as many as 32million Americans may have had the disease at some point in their lives. Globally, up to 14 percent of people are thought to have been infected. (Source: the Mail online | Health)


Saturday 19 November 2022

#MayoClinicRadio podcast: 8/10/19

Listen: Mayo Clinic Radio 8/10/19 On the Mayo Clinic Radio podcast, Dr. Gregory Poland, a Mayo Clinic infectious diseases and vaccine expert, gives an update on infectious disease hot topics, including Lyme disease, the ongoing concern about measles, the hope for a universal flu vaccine and new age guidelines for the HPV vaccine. Also on the podcast, Dr. John Lieske explains how kidney stones form and how [...] (Source: News from Mayo Clinic)


Saturday 19 November 2022

Mayo Clinic Q and A:  Tick-borne illnesses

DEAR MAYO CLINIC: A close friend was diagnosed recently with Lyme disease due to a tick bite. However, I recently read about some new type of tick-borne illness. My family loves to hike and be outdoors, but I'm nervous now about continuing our activities. How can I reduce our risk of illness from insect bites and protect my family? ANSWER: Enjoying the outdoors is a wonderful way to spend quality family time together, but there are certainly… (Source: News from Mayo Clinic)


Saturday 19 November 2022

Lyme disease symptoms: Three parts of your body you should always check for tick bites

LYME disease may have an innocent sounding name, but it ’s a nasty condition transmitted by ticks which, left untreated, can lead to severe health problems. Here are three parts of body you should always check after visiting grassy and woodland areas, as well as other symptoms you should look out for. (Source: Daily Express - Health)


Saturday 19 November 2022

Pfizer buys stake in French vaccine maker Valneva

US pharma group to pay €90.5mn for 8% in deal that will boost joint Lyme disease programme (Source: FT.com - Drugs and Healthcare)


Saturday 19 November 2022

Lyme disease: Most people who experience this sign ‘probably don't' have the condition

LYME disease is a bacterial infection which is spread to humans via tick bites. The most notable symptom is the rash that develops, but not all symptoms associated with the condition necessarily point to Lyme disease. (Source: Daily Express - Health)


Saturday 19 November 2022

Economic Burden of Lyme Disease in High-Incidence Areas Economic Burden of Lyme Disease in High-Incidence Areas

An economic evaluation of the costs associated with Lyme disease underscores the importance of effective prevention measures.Emerging Infectious Diseases (Source: Medscape Today Headlines)


Saturday 19 November 2022

Lyme Carditis Requires Prompt Identification and Treatment Lyme Carditis Requires Prompt Identification and Treatment

Two newly reported cases of fatal Lyme carditis serve as a reminder of the importance of prompt identification and treatment of this potentially life-threatening infection.Reuters Health Information (Source: Medscape Medical News Headlines)

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Saturday 19 November 2022

Mayo Clinic Minute: What to do if you are exposed to Lyme disease

Scientists are studying why tick-borne infections, including Lyme disease, are on the rise and why ticks are expanding into new geographic areas. Lyme disease, the most common tick-borne infection, is caused by the bacteria Borrelia burgdorferi and Borrelia mayonii. It's transmitted by the bite of an infected blacklegged tick, previously known as a deer tick. The Northeast and Upper Midwest are hot spots for Lyme disease, though there are other parts of the U.S. and the world… (Source: News from Mayo Clinic)

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Saturday 19 November 2022

Blog: Standing with people who make me so proud of our union

I’m always so proud of what our union stands for and what we can achieve when we stand together. But sometimes there are days when that’s particularly true – and earlier this week I had one of those days. It started early on a picket line at Whiston Hospital. The strikers – employed by Compass – have a simple demand, to get the same pay and conditions as those they work alongside in our NHS. Their energy, their passion and their unwillingness to give in are truly inspiring. These are the people who keep our NHS – our nation’s greatest achievement – running each day. They clean, they cook and they make sure patients are where they’re meant to be. They embody the incredible values of the NHS and our union, and it’s time that Compass (a company whic...


Saturday 19 November 2022

Insurance Data Shows Big Rise in Lyme Disease in US Insurance Data Shows Big Rise in Lyme Disease in US

The trends show that tick-borne illnesses are becoming a more common concern nationally, not just in the areas where Lyme disease has been found historically.WebMD Health News (Source: Medscape Infectious Diseases Headlines)


Saturday 19 November 2022

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Saturday 19 November 2022

Insurance Data Shows Rise in Lyme Disease in USA

Insurance Data Shows Big Rise in Lyme Disease in US (Source: eMedicineHealth.com)


Saturday 19 November 2022

Lyme Disease Vaccine Could Be Ready In 4 to 5 Years

For now, the only prevention lies in avoiding tick contact but one company, Valneva, is working fervently to develop what they believe will be the world ’s first vaccine against Lyme’s disease. (Source: Forbes.com Healthcare News)


Saturday 19 November 2022

Pfizer tests vaccine to fend off spread of tick-borne Lyme disease

US drugmaker and French partner begin late-stage trial with 14% of global population showing evidence of infection (Source: FT.com - Drugs and Healthcare)


Saturday 19 November 2022

Lyme disease: A peculiar feeling in the head is a warning sign of the condition

LYME disease is a bacterial infection which could lead to severe physical and mental problems if not diagnosed at an early stage. Spotting the early warning signs will ensure prompt treatment and noticing this peculiar feeling in the head could mean you're at risk. (Source: Daily Express - Health)


Saturday 19 November 2022

Major test of first possible Lyme vaccine in 20 years begins

Researchers are seeking thousands of volunteers in the U.S. and Europe. (Source: ABC News: Health)


Saturday 19 November 2022

Lessons From Lyme Disease: Six Reasons The CDC ’s COVID-19 Failure Was Predictable

Lyme disease experts are not surprised by CDC's failure to ensure quick diagnosis of COVID-19. It's failed for 25 years to fix a broken Lyme test. (Source: Forbes.com Healthcare News)


Saturday 19 November 2022

Major test of 1st potential Lyme disease vaccine in 20 years begins in U.S., Europe

Pfizer and French biotech company Valneva are seeking volunteers to test their new vaccine against Lyme disease, which could protect both adults and kids as young as five from the tick-borne illness. (Source: CBC | Health)

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Saturday 19 November 2022

Can Coronavirus Spread Through Secondhand Smoke? Dr. Mallika Marshall Answers Your Questions

BOSTON (CBS) — As Massachusetts continues to fight the coronavirus pandemic, the public has plenty of questions. Dr. Mallika Marshall answered some of those sent to WBZ-TV’s Facebook, Instagram and Twitter accounts. With the upcoming season, we already have troubles with ticks and Lyme disease and mosquitoes and their diseases. How is the coronavirus going to affect this problem? – Ken from north of Boston  Coronavirus is not spread by mosquitoes or ticks, but you’re right, we still have to protect ourselves from insect-borne diseases like Lyme Disease and West Nile Virus. So I would do what we normally do to avoid these insects: use protective clothing and insect repellant and avoid the times of day and locations where they thrive. If I self-isolate for more than two ...


Saturday 19 November 2022

PET scans reveal brain activity related to menopause

PET scans have demonstrated for the first time that only women appear to experienc...Read more on AuntMinnie.comRelated Reading: PET brain scans find links to PTSD severity in 9/11 responders PET tracers reveal long-term consequences of brain injuries Preclinical PET study offers better Alzheimer's detection Carbon-11 PET detects brain inflammation after Lyme disease C-11-based PET tracer could benefit arthritis patients (Source: AuntMinnie.com Headlines)


Saturday 19 November 2022

Coronavirus update: Lyme disease symptoms could be mistaken for COVID-19 - signs to spot

CORONAVIRUS symptoms have been shown to range from a dry cough to conjunctivitis, but some of these symptoms are also linked to other conditions such as Lyme disease. How can you tell the difference between COVID-19 and Lyme disease? (Source: Daily Express - Health)


Saturday 19 November 2022

Lyme disease vaccine in late-stage trials would be first in 20 years

If successful, the vaccine would be the first against Lyme disease in the United States since Lymerix, which was discontinued in 2002 because of poor sales. (Source: Washington Post: To Your Health)


Saturday 19 November 2022

Everything You Need to Know About Lyme Disease

TUESDAY, April 23, 2019 -- With growing concern about mosquito-borne viruses such as Zika, it's easy to let down your guard when it comes to ticks. But Lyme disease is still a danger, especially in the Northeast and upper Midwest. In fact, it has... (Source: Drugs.com - Daily MedNews)


Saturday 19 November 2022

States vs Masks; Lyme Vax Trial Begins; Weapons Stockpile in Hospital Closet

(MedPage Today) -- Note that some links may require registration or subscription. A group of 23 state attorneys general led by Florida told a federal court Monday that the CDC does not have the legal authority to impose a nationwide transportation... (Source: MedPage Today Public Health)


Saturday 19 November 2022

Health Tip: Early Signs of Lyme Disease

-- Lyme disease is caused by a bacterium that may be acquired from the bite of an infected tick. Left untreated, the infection can spread throughout the body and cause serious complications, says the U.S. Centers for Disease Control and... (Source: Drugs.com - Daily MedNews)


Saturday 19 November 2022

Pfizer starts late-stage clinical trials Lyme disease vaccine

A new Lyme disease could be available in the U.S. as early as 2025, as Pfizer has launched final clinical trials for its jab, VLA15. The company is aiming to apply for FDA approval in 2025. (Source: the Mail online | Health)


Saturday 19 November 2022

Enhancement of Lyme Disease Risk by Landscape Connectivity Enhancement of Lyme Disease Risk by Landscape Connectivity

Find out how park connectivity and landscape composition may contribute to Lyme disease risk in urban areas.Emerging Infectious Diseases (Source: Medscape Today Headlines)

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Saturday 19 November 2022

Pfizer Begins Trial for Lyme Disease Vaccine Pfizer Begins Trial for Lyme Disease Vaccine

If the trial succeeds, the vaccine could be the first human vaccine for the tick-borne illness in the US in two decades.WebMD Health News (Source: Medscape PublicHealth Headlines)

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Saturday 19 November 2022

The Dengue Dance?

Discussion Dengue is an important arboviral infection that affects about 40% of the world population. It is found mainly in topical and subtropical areas of the world mainly in developing countries but it range is spreading including the United States. A review of common arboviruses can be found here. It is a flaviavirus with 4 distinct serotypes named DENV-1 through DENV-4 and is spread by A. aegypti a day biting mosquito. Infection with one serotype confers immunity to that serotype but not the others. It does offer some protection for cross-infection but this only lasts a few months. Incubation period is 3-14 days with an average of 7 after exposure. A primary infection is usually benign. A second infection with another serotype or multiple infections with different serotypes can caus...


Saturday 19 November 2022

Only Lyme disease vaccine in development goes to Phase 3 trial

Vaccine maker Pfizer says it has begun Phase 3 clinical trial of its vaccine candidate against Lyme disease with French vaccine company Valneva SE. (Source: CNN.com - Health)


Saturday 19 November 2022

Health group says Ontario must do more to protect children from climate change

An Ontario health advocacy group is calling for more action to protect children from the harmful impacts of climate change. The group says cases of asthma, heat stroke and Lyme disease could all be on the rise in the coming decades. (Source: CBC | Health)


Saturday 19 November 2022

A Hotter World Means More Disease Outbreaks in Our Future

As global temperatures have risen in recent decades, so have the number of outbreaks of infectious diseases. SARS, MERS, Zika, West Nile, COVID-19, and now clusters of monkeypox and polio have all recently threatened public health. That’s no coincidence. In a study published in August in Nature Climate Change, researchers tried to understand the relationship between major environmental changes related to higher greenhouse gas emissions—including global warming, rising sea levels, storms, floods, drought, and heat waves—and the outbreaks of 375 human infectious diseases caused by viruses, bacteria, and other pathogens. They found that 58% of these public-health threats were fueled by climate change. [time-brightcove not-tgx=”true”] “The health impacts of ...


Saturday 19 November 2022

CDC Recommendation for Serologic Diagnosis of Lyme Disease CDC Recommendation for Serologic Diagnosis of Lyme Disease

Recently, the FDA cleared several Lyme disease serologic assays with new indications for use, allowing for an EIA rather than western immunoblot assay as a confirmatory test.Morbidity & Mortality Weekly Report (Source: Medscape Today Headlines)


Saturday 19 November 2022

Vaccine could ward off lyme disease to help the thousands of Britons

A vaccine designed to protect against Lyme disease is being trialled and, if successful, could be available for use in 2025. Lyme disease is an infection spread by ticks. (Source: the Mail online | Health)


Saturday 19 November 2022

PET uncovers heightened ischemia after TBI

A novel PET imaging technique has uncovered high levels of ischemia in patients...Read more on AuntMinnie.comRelated Reading: PET/MRI sheds light on cerebral vascular risk factors Flortaucipir-PET shows tau accumulation after one TBI PET, MRI show physical activity aids brain health Carbon-11 PET detects brain inflammation after Lyme disease SNMMI: Cerebrovascular risk tied to Alzheimer's disease (Source: AuntMinnie.com Headlines)


Saturday 19 November 2022

Kentucky has the fastest growing lyme disease outbreak in the US, insurance data suggests

Experts warn high seasonal temperatures are opening up new habitats for northern ticks in mountainous areas of southern states. But increasesd awareness may also fuel the rise. (Source: the Mail online | Health)


Saturday 19 November 2022

‘I’ve Been Battling and Overcoming.’ Justin Bieber Confirms Lyme Disease Diagnosis

(NEW YORK) — Justin Bieber says that he has been battling Lyme disease. In an Instagram post on Wednesday, the pop star wrote that “it’s been a rough couple years but (I’m) getting the right treatment that will help treat this so far incurable disease and I will be back and better than ever.” Lyme disease is transmitted by Ixodes ticks, also known as deer ticks. Lyme can cause flu-like conditions, neurological problems, joint paint and other symptoms. “While a lot of people kept saying justin Bieber looks like (expletive), on meth etc. they failed to realize I’ve been recently diagnosed with Lyme disease, not only that but had a serious case of chronic mono which affected my, skin, brain function, energy, and overall health,” Bieber wrote. Th...

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Saturday 19 November 2022

Shania Twain's Lyme Disease

(MedPage Today) -- Netflix's new documentary, Shania Twain: Not Just a Girl, follows the country singer from Nashville newcomer to international icon. Twain is the best-selling female country artist of all time, with three diamond-certified albums... (Source: MedPage Today Infectious Disease)

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Saturday 19 November 2022

Lyme Disease at a North Carolina Outdoor Wilderness Camp Lyme Disease at a North Carolina Outdoor Wilderness Camp

This cluster of Lyme disease cases in North Carolina indicates that the disease may be expanding further south.Morbidity & Mortality Weekly Report (Source: Medscape Today Headlines)


Saturday 19 November 2022

Could a new vaccine tackle rising rates of Lyme disease? | podcast

According to a recent study, more than 14% of the world ’s population probably has, or has had, tick-borne Lyme disease – an infection that can cause long and debilitating symptoms. That number is set to rise too, as climate and environment changes continue to increase tick populations and distribution.To help prevent some of these cases, pharmaceutical company Pfizer and biotech company Valneva will soon be testing a new vaccine against Lyme disease with 6,000 volunteers across Europe and in the US.Madeleine Finlay speaks to Dr Eoin Healy about what Lyme disease is and how the vaccine works, and hears from a special guest about their own experience of getting ill with the disease.Archive: BBC News, TODAYContinue reading... (Source: Guardian Unlimited Science)


Saturday 19 November 2022

Warmer weather means it's time to be tick aware

As warm weather sends people outdoors, some are encountering tenacious pests. Ticks go for blood in the hardest-to-reach places on the human body and put you at risk for Lyme disease. Here's what you need to know about staying tick-safe. (Source: CNN.com - Health)


Saturday 19 November 2022

Deer Are Spreading Lyme Ticks in Suburban Backyards

TUESDAY, Sept. 20, 2022 -- They look so cute, grazing quietly in your backyard. But the overpopulation of white-tailed deer across the Northeastern United States could help spread Lyme disease and another tick-borne illness, anaplasmosis, especially... (Source: Drugs.com - Daily MedNews)


Saturday 19 November 2022

Lyme Disease Now a Threat in City Parks

Infected ticks were mostly found in forested parks with vegetation around the edges and connected to each other. (Source: WebMD Health)

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Saturday 19 November 2022

Woman, now 29, needs 16 joint replacements after catching Lyme disease

Meghan Bradshaw, now 29 and from Charlotte in North Carolina, was described by doctors as the 'worst case' of Lyme disease they had seen. She now says she is a 'bionic woman'. (Source: the Mail online | Health)


Saturday 19 November 2022

Ottawa considered at-risk area for lyme disease, warns public health

Ottawa Public Health has stopped collecting ticks after it found a high number of the arachnids within the city carry Lyme disease. (Source: CBC | Health)


Saturday 19 November 2022

Deer Are Spreading Lyme Ticks in Suburban Backyards

A new study suggests the overpopulation of white-tailed deer across the Northeastern U.S. could help spread Lyme disease, especially in suburban areas. (Source: WebMD Health)


Saturday 19 November 2022

UK Lyme disease cases may be three times higher than estimated

Researchers say tick-borne disease ‘is everywhere’ with 8,000 diagnoses likely in 2019Cases of Lyme disease in the UK may be three times higher than previous estimates, according to new research.After analysing the anonymous medical records of 8.4 million people from across the UK, scientists forecast that the total number of Lyme disease diagnoses in the UK could top 8,000 in 2019, compared withpreviousestimates of between 2,000 and 3,000 annual diagnoses.Continue reading... (Source: Guardian Unlimited Science)


Saturday 19 November 2022

Whole Blood RT-PCR Testing for Diagnosis of Early Lyme Disease Whole Blood RT-PCR Testing for Diagnosis of Early Lyme Disease

Is whole blood-RT-PCR useful as a diagnostic aid for early Lyme disease when done in conjunction with serology testing?American Journal of Clinical Pathology (Source: Medscape Today Headlines)

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Saturday 19 November 2022

CVS Health partners with ixlayer for branded at-home testing kits

Consumers can use the tests to detect Lyme disease, vitamin D levels, thyroid function, and sexually-transmitted infections. (Source: mobihealthnews)


Saturday 19 November 2022

Lyme Neuroborreliosis: Known Knowns, Known Unknowns Lyme Neuroborreliosis: Known Knowns, Known Unknowns

This review provides an approach to patients with neurological disorders in whom a diagnosis of Lyme neuroborreliosis is being considered. What does and does not constitute nervous system disease?Brain (Source: Medscape Today Headlines)


Saturday 19 November 2022

Her Face Started Drooping. What Was Wrong?

And if this was Bell ’s palsy, why wasn’t there improvement after a full year? (Source: NYT Health)


Saturday 19 November 2022

Brain Imaging Validates Cognitive Problems After Lyme Disease Brain Imaging Validates Cognitive Problems After Lyme Disease

Many patients who have had Lyme disease struggle with cognitive challenges, even after treatment. This new imaging study shows changes in white matter that might explain these symptoms.Medscape Medical News (Source: Medscape Psychiatry Headlines)


Saturday 19 November 2022

Medical News Today: Lyme disease: Why does joint pain persist?

Lyme disease can cause long-term joint inflammation that lasts long after the body has cleared the infection. A new study uncovers how this might happen. (Source: Health News from Medical News Today)


Saturday 19 November 2022

Can long Covid research unlock other great medical mysteries of our time?

Attention and funding for research into mononucleosis, HIV, Lyme, Ebola, Sars and other infections have historically been limited – but long Covid changed thatRead the Guardian ’s new series, Living with long CovidAs the coronavirus grew from a fleeting concern to a full-blown panic, Lili Lim started to hear about people for whom the illness lasted weeks or even months. There were news stories of young people that couldn ’t shake their fatigue or cognitive malaise, of folks who had to quit their job due to debilitating exhaustion.For Lim, the symptoms were frighteningly recognizable.Continue reading... (Source: Guardian Unlimited Science)

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Saturday 19 November 2022

Want to Stop the Next Pandemic? Start Protecting Wildlife Habitats

(Bloomberg) — There are four critical facets of pandemic prevention, according to Lee Hannah, senior scientist at Conservation International. Three of them make immediate sense against the backdrop of our current emergency: stockpile masks and respirators; have testing infrastructure ready; and ban the global wildlife trade, including the open animal markets where COVID-19 may have first infected people. His fourth recommendation is more grandiose: “Take care of nature.” The assault on ecosystems that allowed COVID-19 to jump from animals to humans went far beyond merchants hunting and selling rare wildlife. Biodiversity—that is, the health of the entire ecosystem—can restrain pathogens before they ever leave the wild. “We need to tell people right now t...

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Saturday 19 November 2022

An Untreated Tick Bite Made Her the 'Bionic Woman'

Meghan Bradshaw has had 16 joint reconstructions and eight joint replacements, all before age 30. This is due to a late diagnosis of Lyme disease, which is a tick-borne illness that can be treated and cured if detected early. (Source: WebMD Health)


Saturday 19 November 2022

Lyme Disease Cases On The Rise In US, Report Says

NEW YORK (CBS) – The United States has seen a big rise in the number of Lyme disease cases. A new study finds that the number of Americans diagnosed with the illness more than doubled over the past decade. Researchers at FAIR looked at private health insurance claims from 2007 to 2018. They found the biggest increase was in urban areas where claims for Lyme disease increased by more than 120%. Read The Report (PDF) “Lyme disease is the nation’s predominant tick-borne disease, and it is growing,” FAIR said in its report. Massachusetts was among the Top 10 states with the highest percentages of insurance claims for Lyme. The infection is spread through tick bites and can affect joints, the nervous system and heart if it goes untreated. (Source: WBZ-TV - Breaking News, Weather and Spo...


Saturday 19 November 2022

New grants support research on factors affecting infectious disease transmission

Headlines on COVID-19 and monkeypox underscore the importance of understanding infectious diseases and how they're transmitted. Scientists are studying these diseases, such as hand, foot and mouth disease and Lyme disease, to gain insights into how … (Source: NSF News)


Saturday 19 November 2022

Updated CDC Recommendation for Serologic Diagnosis of Lyme Disease

Lyme disease is a tickborne zoonosis for which serologic testing is the principal means of laboratory diagnosis. (Source: CDC Morbidity and Mortality Weekly Report)

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Saturday 19 November 2022

Despite Threat of Lyme Disease, Tick Control Lags Across U.S.

WEDNESDAY, June 17, 2020 -- Tick monitoring and control is lacking in much of the United States despite a steady increase in tick-borne illnesses, such as Lyme disease, a new study finds. In the United States, tick-borne illnesses more than doubled... (Source: Drugs.com - Daily MedNews)


Saturday 19 November 2022

Model predicts where ticks, Lyme disease will appear next in Midwest states

(University of Illinois at Urbana-Champaign, News Bureau) By drawing from decades of studies, scientists created a timeline marking the arrival of black-legged ticks, also known as deer ticks, in hundreds of counties across 10 Midwestern states. They used these data - along with an analysis of county-level landscape features associated with the spread of ticks - to build a model that can predict where ticks are likely to appear in future years. (Source: EurekAlert! - Infectious and Emerging Diseases)

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Saturday 19 November 2022

Notes from the Field: Four Cases of Lyme Disease at an Outdoor Wilderness Camp --- North Carolina, 2017 and 2019

The recent discovery of Lyme-infected ticks at the location of an outdoor wilderness program in North Carolina highlights the importance of vectorborne disease prevention. (Source: CDC Morbidity and Mortality Weekly Report)


Saturday 19 November 2022

Lyme disease symptoms: Four early signs of being bitten by an infected tick

LYME disease is a bacterial infection spread to humans by infected ticks. The condition can be treated effectively if detected early, but a delay in recognising it can increase the risk of developing long-lasting symptoms. (Source: Daily Express - Health)


Saturday 19 November 2022

Two years after a tick bite, my wife's an invalid. DR MARTIN SCURR answers your health questions

DR MARTIN SCURR: Pat Toovey from Norfolk found a tick on his wife's back two years ago and she is constantly in pain and struggles to get out of bed. He fears she has Lyme disease. (Source: the Mail online | Health)