The latest publications of scientific medical research, articles and news on Lyme disease from many resources are automatically displayed here.
Friday 9 June 2023
Killing ticks in an area reduces the number carrying the main bacterium that causes Lyme disease, but a large study found it does not lead to fewer reports of people getting sick (Source: New Scientist - Health)
Friday 9 June 2023
Curr Opin Microbiol. 2023 Jun 4;74:102332. doi: 10.1016/j.mib.2023.102332. Online ahead of print.ABSTRACTThe Lyme disease spirochete persists in nature through cycles between ticks and vertebrates. Although the spirochete interacts with numerous, distinct tissues and environmental conditions during its infectious cycle, Borrelia burgdorferi appears to possess a limited ability to sense its external environment. This apparent paradox is being resolved through detailed investigations of the molecular mechanisms through which B. burgdorferi controls production of virulence-associated factors such as the Erp outer surface proteins. The results have led to development of a model for how B. burgdorferi controls expression of its diverse proteins, wherein physiological and metabolic states that a...
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Friday 9 June 2023
CONCLUSION: We successfully developed a Multiplex PCR assay for differential diagnosis of rickettsiosis, Lyme disease and scrub typhus that could be a rapid and easy option in clinical and epidemiological practice.PMID:36124484 | DOI:10.4103/0972-9062.337506 (Source: Journal of Vector Borne Diseases)
Friday 9 June 2023
Conclusions: These findings support the idea that, as one of many factors, the contact with spirochetal antigens may indicate a potential positive correlation with the formation of cardiovascular changes. More research, not only at the diagnostic level but also at the advanced research level, is needed.PMID:36767604 | DOI:10.3390/ijerph20032239 (Source: Atherosclerosis)
Friday 9 June 2023
In this study, we experimentally characterized specific domains of P66 with regard to structure and function. First, we aligned the amino acid sequences of P66 from Lyme disease-causing Borrelia and relapsing fever-causing Borrelia to identify conserved and unique domains between these disease-causing clades. Then, we examined whether specific domains of P66 are exposed on the surface of the bacteria by introducing c-Myc epitope tags into each domain of interest. The c-Myc epitope tag inserted C-terminally to E33 (highly conserved domain), to T187 (integrin binding region domain and a non-conserved domain), and to E334 (non-conserved domain) were all detected on the surface of Borrelia burgdorferi. The c-Myc epitope tag inserted C-terminally to E33 and D303 in conserved domains disrupted P...
Friday 9 June 2023
Contributors : Timothy Casselli ; Catherine A BrissetteSeries Type : Methylation profiling by high throughput sequencingOrganism : Borreliella mayoniiSingle Molecule Real Time (SMRT) sequencing was utilized to map the genome-wide m6A methylation pattern in B. mayonii. Consensus modified motifs were identified in wildtype B. mayonii as well as clonal isolates lacking plasmids that encode predicted methyltransferases. Two conserved m6A modification motifs were identified, and were fully attributable to the presence of specific methyltransferases. (Source: GEO: Gene Expression Omnibus)
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Friday 9 June 2023
We present a case of sudden sensorineural hearing loss and rapidly progressive facial palsy in a female patient in her 40s with no, apparently, notable past medical or surgical history. Investigations revealed a positive serology forB. burgdoferi and the MRI allowed us to identify suggestive signs of Lyme meningitis with multiple cranial nerve involvement. After diagnosis, the patient was treated with intravenous ceftriaxone with a full recovery of sensorineural deafness and facial palsy. This case report highlights the importance of collecting a complete medical history in all cases of facial palsy and sudden hearing loss while presenting an infrequent clinical presentation of early disseminated Lyme disease with neuroborreliosis. (Source: Clinical Case Reports)
Friday 9 June 2023
CONCLUSION: Using quantitative proteomics, we identified differential protein production in I. ricinus salivary glands in response to B. afzelii infection and different feeding conditions. These results provide novel insights into the process of I. ricinus feeding and B. afzelii transmission and revealed novel candidates for an anti-tick vaccine.PMID:36797101 | DOI:10.1016/j.vaccine.2023.02.003 (Source: Vaccine)
Friday 9 June 2023
Conclusion Our results strongly indicate that there are no benefits of doxycycline treatment beyond 2 weeks in European LNB. Trial registration number 2015-001481-25. (Source: Journal of Neurology, Neurosurgery and Psychiatry)
Friday 9 June 2023
AbstractWe aimed to describe the clinical characteristics, management, and residual symptoms (RS) in patients with definite and possible Lyme neuroborreliosis (LNB). We conducted a retrospective French multicenter cohort study (2010 –2020). Cases of LNB were defined as clinical manifestations attributed to LNB and a positiveBorrelia-specific intrathecal antibody index (AI) ( “possible” LNB) and with pleocytosis (“definite” LNB). Risk factors of RS were determined using a logistic regression model. We included 138 adult patients with a positive AI. Mean age was 59.5 years (± 14.7). The median duration of symptoms before diagnosis was 1.0 [0.5–4.0] months. T he most frequent manifestation was radicular pain (n = 79, 57%). Complete cerebrospinal fluid (CSF) leukocyte analy...
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Friday 9 June 2023
Praxis (Bern 1994). 2022;111(14):779-787. doi: 10.1024/1661-8157/a003939.ABSTRACTCME: Neuroborreliosis Abstract. Lyme disease is the most common infectious disease transmitted by ticks throughout Europe. Bacteria of the Borrelia burgdorferi complex are transmitted via tick bites to humans. The typical initial presentation is a localized infection of the skin (Erythema migrans). If the patient is not treated with antibiotics, a disseminated infection might occur, presenting as neurological Lyme disease, Lyme carditis, Lyme arthritis or Acrodermatitis chronica atrophicans. A neuroborreliosis occurs in 3-15% of the cases. It may present as polyradiculitis, meningitis or - in rare cases - as encephalomyelitis. The antimicrobial therapy of neuroborreliosis is doxycyclin, ceftriaxone or penicill...
Friday 9 June 2023
This study provides the first evidence ofB.miyamotoi exposure in human and rodent populations in Thailand and the possible roles of local rodent species andIxodes granulatus tick in its enzootic transmission cycle in nature. (Source: PLoS Neglected Tropical Diseases)
Friday 9 June 2023
Tex Heart Inst J. 2022 Sep 1;49(5):e207515. doi: 10.14503/THIJ-20-7515.ABSTRACTA 19-year-old woman with newly diagnosed Lyme disease presented with complete heart block and an accompanying escape rhythm with a right bundle branch block morphology. With antibiotics, her dysrhythmia resolved completely within 24 hours of presentation. This case highlights an unusual electrocardiographic manifestation of Lyme carditis.PMID:36315846 | DOI:10.14503/THIJ-20-7515 (Source: Texas Heart Institute Journal)
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Friday 9 June 2023
We report the case of a middle-aged female who presente d with complaints of alternating facial palsy and the diligent journey that we took to finally reach a diagnosis of Lyme neuroborreliosis. (Source: Indian Journal of Otolaryngology and Head and Neck Surgery)
Friday 9 June 2023
Tex Heart Inst J. 2022 Sep 1;49(5):e207515. doi: 10.14503/THIJ-20-7515.ABSTRACTA 19-year-old woman with newly diagnosed Lyme disease presented with complete heart block and an accompanying escape rhythm with a right bundle branch block morphology. With antibiotics, her dysrhythmia resolved completely within 24 hours of presentation. This case highlights an unusual electrocardiographic manifestation of Lyme carditis.PMID:36315846 | DOI:10.14503/THIJ-20-7515 (Source: Texas Heart Institute Journal)
Friday 9 June 2023
This study aimed to analyze human-biting Ixodes scapularis ticks submitted to TickReport tick testing service from 2015–2019 in Massachusetts to (1) examine possible patterns of pathogen-positive adult and nymphal ticks over time and (2) explore how socioeconomic factors can influence tick submissions. A passive surveillance data set of ticks and tick-borne pathogens was conducted over 5 years (2015–2019) in Massachusetts. The percentages of four tick-borne pathogens: Borrelia burgdorferi, Anaplasma phagocytophilum, Babesia microti, and Borrelia miyamotoi were determined by Massachusetts county and by month and year. Regression models were used to examine the association between zip-code-level socioeconomic factors and submissions. A total of 13,598 I. scapulari...
Friday 9 June 2023
Tex Heart Inst J. 2022 Sep 1;49(5):e207515. doi: 10.14503/THIJ-20-7515.ABSTRACTA 19-year-old woman with newly diagnosed Lyme disease presented with complete heart block and an accompanying escape rhythm with a right bundle branch block morphology. With antibiotics, her dysrhythmia resolved completely within 24 hours of presentation. This case highlights an unusual electrocardiographic manifestation of Lyme carditis.PMID:36315846 | DOI:10.14503/THIJ-20-7515 (Source: Texas Heart Institute Journal)
Friday 9 June 2023
Infection and Immunity, Ahead of Print. (Source: Infection and Immunity)
Friday 9 June 2023
Tex Heart Inst J. 2022 Sep 1;49(5):e207515. doi: 10.14503/THIJ-20-7515.ABSTRACTA 19-year-old woman with newly diagnosed Lyme disease presented with complete heart block and an accompanying escape rhythm with a right bundle branch block morphology. With antibiotics, her dysrhythmia resolved completely within 24 hours of presentation. This case highlights an unusual electrocardiographic manifestation of Lyme carditis.PMID:36315846 | DOI:10.14503/THIJ-20-7515 (Source: Texas Heart Institute Journal)
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Friday 9 June 2023
Infection and Immunity, Ahead of Print. (Source: Infection and Immunity)
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Friday 9 June 2023
Tex Heart Inst J. 2022 Sep 1;49(5):e207515. doi: 10.14503/THIJ-20-7515.ABSTRACTA 19-year-old woman with newly diagnosed Lyme disease presented with complete heart block and an accompanying escape rhythm with a right bundle branch block morphology. With antibiotics, her dysrhythmia resolved completely within 24 hours of presentation. This case highlights an unusual electrocardiographic manifestation of Lyme carditis.PMID:36315846 | DOI:10.14503/THIJ-20-7515 (Source: Texas Heart Institute Journal)
Friday 9 June 2023
Introduction Lyme disease is the most common vectorborne disease in the Northern hemisphere with more than 400 000 new cases in the USA annually. Lyme meningitis is an uncommon but potentially serious clinical manifestation of Lyme disease. Intravenous ceftriaxone had been the first-line treatment for Lyme meningitis, but is associated with a high rate of complications. Although efficacy and effectiveness (or real-world evidence) data for oral doxycycline are limited, practice guidelines were recently expanded to recommend either oral doxycycline or ceftriaxone as first-line treatments for Lyme meningitis. Our goal is to compare oral doxycycline with intravenous ceftriaxone for the treatment of Lyme meningitis on short-term recovery and long-term quality of life. Methods and analysis We a...
Friday 9 June 2023
This report will have people taking a closer look at some of their casts.” Decades before the word “dinosaur” entered the scientific lexicon, ichthyosaurs were the rock stars of the nascent paleontology field. The first complete ichthyosaur skeleton hailed from Lyme Regis, a seaside town along southern England’s iconic Jurassic Coast. Eroding out of the area’s wave-battered limestone cliffs are the inhabitants of a tropical sea from 200 million years ago, including squidlike ammonites, pterosaurs, and a slew of marine reptiles, including ichthyosaurs and long-necked plesiosaurs. Fossil hunters have flocked to these crumbling cliffs for centuries, thanks in part to the prodigious collecting of pioneering paleontologist Mary Anning in the early 1800s. The daughter of an a...
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Friday 9 June 2023
This study aimed to examine whether patient skin colour can affect the diagnostic ability and confidence of medical students, and their cognitive reasoning processes. We presented students with 12 different clinical presentations on both white skin (WS) and non-white skin (NWS). A think aloud (TA) study was conducted to explore students ’ cognitive reasoning processes (n = 8). An online quiz was also conducted where students submitted a diagnosis and confidence level for each clinical presentation (n = 185). In the TA interviews, students used similar levels of information gathering and analytical reasoning for each skin type but appeared to display increased uncertainty and reduced non-analytical reasoning methods for the NWS images compared to the WS images. In the online quiz,...
Friday 9 June 2023
ConclusionsMRI cranial nerve enhancement is common in LNB patients, but it can be clinically occult. Facial and oculomotor nerves are most often affected. Enhancement of the facial nerve distal internal auditory canal and parotid segments correlate with degree of facial palsy. (Source: Neuroradiology)
Friday 9 June 2023
AbstractLyme neuroborreliosis (LNB) is a manifestation of Lyme disease involving the central and peripheral nervous system. It is caused by the spirocheteBorrelia burgdorferi, transmitted by tick bites to a human host. Clinical signs of LNB develop after the dissemination of the pathogen to the nervous system. The infection occurs in children and adults, but the clinical manifestations differ. In adults, painful meningoradicultis is the most common manifestation of LNB, while children often present with facial nerve palsy and/or subacute meningitis. Subacute headache can be the only manifestation of LNB in children, especially during the summer months in Lyme disease-endemic regions. Non-specific symptoms, such as loss of appetite, fatigue or mood changes, may also occur, especially in you...
Friday 9 June 2023
J. Stark et al. (Source: Emerging Infectious Diseases Journal)
Friday 9 June 2023
The RNA polymerase alternative σ factor RpoS in Borrelia burgdorferi (Bb), the Lyme disease pathogen, is responsible for programmatic-positive and -negative gene regulation essential for the spirochete’s dual-host enzootic cycle. RpoS is expressed during tick-to-mammal transmission and throughout mammalian infection. Although the mammalian-phase RpoS regulon is well described, its counterpart during the transmission blood meal is unknown. Here, we used Bb-specific transcript enrichment by tick-borne disease capture sequencing (TBDCapSeq) to compare the transcriptomes of WT and ΔrpoS Bb in engorged nymphs and following mammalian host-adaptation within dialysis membrane chambers. TBDCapSeq revealed dramatic changes in the contours of the RpoS regulon within ticks and mammals and further ...
Friday 9 June 2023
International Journal of Environmental Research and Public Health doi: 10.3390/ijerph192214893 Authors: Krzysztof A. Kaczmarek Katarzyna Szwabe Irmina Urbanek Pawel Ptaszynski Aleksander Strzelecki Jerzy K. Wranicz Iwona Cygankiewicz Infections with Borrelia may cause cardiac conduction system abnormalities, including atrioventricular blocks (AVBs). Therefore, we aimed to identify patients in whom Lyme carditis (LC) could be considered as the initial diagnosis among consecutive subjects who were referred for implantation of a permanent pacemaker due to symptomatic AVBs. To date, such a systematic evaluation has not been reported yet. Validation of the Suspicious Index for Lyme Carditis (SILC) in our study population was considered as an additional goal. We investigated...
Friday 9 June 2023
Infection and Immunity, Ahead of Print. (Source: Infection and Immunity)
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Friday 9 June 2023
Vector-Borne and Zoonotic Diseases, Ahead of Print. (Source: Vector-Borne and Zoonotic Diseases)
Friday 9 June 2023
CONCLUSIONS: The Sofia 2 Lyme test performs well when compared with the Zeus VlsE1/pepC10 IgG/IgM in a two-tiered testing algorithm.PMID:36881650 | DOI:10.1093/ajcp/aqad007 (Source: American Journal of Clinical Pathology)
Friday 9 June 2023
Lyme borreliosis (LB) is the most common tick-borne infectious disease in the northern hemisphere. The diagnosis of LB is usually made by clinical symptoms and subsequently supported by serology. In Europe, a ... (Source: BMC Infectious Diseases)
Friday 9 June 2023
Biochem Biophys Res Commun. 2023 Feb 27;654:40-46. doi: 10.1016/j.bbrc.2023.02.044. Online ahead of print.ABSTRACTThe Borrelia burgdorferi SpoVG protein has previously been found to be a DNA- and RNA-binding protein. To aid in the elucidation of ligand motifs, affinities for numerous RNAs, ssDNAs, and dsDNAs were measured and compared. The loci used in the study were spoVG, glpFKD, erpAB, bb0242, flaB, and ospAB, with particular focus on the untranslated 5' portion of the mRNAs. Performing binding and competition assays yielded that the 5' end of spoVG mRNA had the highest affinity while the lowest observed affinity was to the 5' end of flaB mRNA. Mutagenesis studies of spoVG RNA and ssDNA sequences suggested that the formation of SpoVG-nucleic acid complexes are not entirely dependent on ...
Friday 9 June 2023
In this study, five unique tissue types were sampled from 90 mice and screened for B. burgdorferi infections. This initial screening revealed a 63% overall B. burgdorferi infection rate in the mice collected (57/90). A total of 163 tissues (30.4%) tested positive for B. burgdorferi infections and when mapped to Borreliella types, 143,894 of the initial 322,480 reads mapped to 10 of the reference sequences in the ospC strain library constructed for this study at a 97% MOI. Two tissue types, the ear and the tongue, each accounted for 90% of the observed Borreliella sequence diversity in the tissue samples surveyed. The largest amount of variation was observed in an individual ear tissue sample with six ospC sequence types, which is equivalent to 60% of the observed variation seen across all ...
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Friday 9 June 2023
Trends Parasitol. 2023 Mar 6:S1471-4922(23)00034-X. doi: 10.1016/j.pt.2023.02.005. Online ahead of print.ABSTRACTBiodiversity loss and the emergence of zoonotic diseases are two major global challenges. An urgent question is how ecosystems and wildlife communities can be restored whilst minimizing the risk of zoonotic diseases carried by wildlife. Here, we evaluate how current ambitions to restore Europe's natural ecosystems may affect the hazard of diseases vectored by the tick Ixodes ricinus at different scales. We find that effects of restoration efforts on tick abundance are relatively straightforward but that the interacting effects of vertebrate diversity and abundance on pathogen transmission are insufficiently known. Long-term integrated surveillance of wildlife communities, ticks,...
Friday 9 June 2023
As a consequence of global temperature rise, ticks (Ixodida) and tick-borne diseases are emerging. During tick attachment to human skin, the feeding cavity becomes a site of transmission for tick salivary compounds, which can exert immunosuppressive effects. Tick-borne pathogens including Borrelia burgdorferi may benefit from dampened immune activation at the bite site. We therefore assessed local and circulating human immune cells and cytokine secretion upon tick bite and developed a human skin explant model mimicking Ixodes ricinus bite. (Source: Journal of Investigative Dermatology)
Friday 9 June 2023
Biochem Biophys Res Commun. 2023 Feb 27;654:40-46. doi: 10.1016/j.bbrc.2023.02.044. Online ahead of print.ABSTRACTThe Borrelia burgdorferi SpoVG protein has previously been found to be a DNA- and RNA-binding protein. To aid in the elucidation of ligand motifs, affinities for numerous RNAs, ssDNAs, and dsDNAs were measured and compared. The loci used in the study were spoVG, glpFKD, erpAB, bb0242, flaB, and ospAB, with particular focus on the untranslated 5' portion of the mRNAs. Performing binding and competition assays yielded that the 5' end of spoVG mRNA had the highest affinity while the lowest observed affinity was to the 5' end of flaB mRNA. Mutagenesis studies of spoVG RNA and ssDNA sequences suggested that the formation of SpoVG-nucleic acid complexes are not entirely dependent on ...
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Friday 9 June 2023
A shorter course of oral doxycycline is effective in treating erythema migrans, the most frequent manifestation of early Lyme borreliosis, and can reduce harmful antibiotic use, trialists recently reported. (Source: JAMA)
Friday 9 June 2023
Conclusion: Rheumatoid arthritis was the most common systemic autoimmune disease association, while syphilis was the most common infectious disease associated with scleritis patients. Our study suggests that patients with nodular scleritis have a lower risk of having an associated immune-mediated disease.PMID:36902755 | DOI:10.3390/jcm12051969 (Source: Herpes)
Friday 9 June 2023
ConclusionsWe propose that CD8+ T cell-mediated cytotoxicity, CD4+ T cell help, autoantibodies to vascular antigens, and complement deposition, may each have a role in microvasculature damage in post-antibiotic LA.This article is protected by copyright. All rights reserved. (Source: Arthritis and Rheumatology)
Friday 9 June 2023
In this study, we developed a lipid nanoparticle (LNP)-encapsulated DNA vaccine encoding outer surface protein C type A (OspC-type A) of B. burgdorferi.ResultsVaccination of C3H/HeN mice with two doses of the candidate vaccine induced significant OspC-type A-specific antibody titres and borreliacidal activity. Analysis of the bacterial burden following needle challenge with B. burgdorferi (OspC-type A) revealed that the candidate vaccine afforded effective protection against homologous infection across a range of susceptible tissues. Notably, vaccinated mice were protected against carditis and lymphadenopathy associated with Lyme borreliosis.DiscussionOverall, the results of this study provide support for the use of a DNA-LNP platform for the development of LD vaccines. (Source: Frontiers ...
Friday 9 June 2023
Previous studies have observed an increased incidence of Cetuximab-induced hypersensitivity infusion reactions (CI-IRs) in the southeastern states of the USA. Tick ’s bites were suspected of generating cross-re... (Source: BMC Cancer)
Friday 9 June 2023
Conclusion CSF-sCD163 is diagnostic for neuroborreliosis with an optimal cut-off of 210 µg/l. Combining ReaScan-CXCL13 with CSF-sCD163 increases AUC. Plasma-sCD163 cannot monitor treatment response.PMID:36931585 | DOI:10.1016/j.cca.2023.117299 (Source: International Journal of Clinical Chemistry)
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Friday 9 June 2023
J Immunol. 2022 Nov 23:ji2101166. doi: 10.4049/jimmunol.2101166. Online ahead of print.ABSTRACTγδ T cells reside at mucosal and epithelial barriers, and they often accumulate at sites of inflammation, both infectious and autoimmune, as well as in certain tumors. However, progress in understanding their function is considerably hampered by a lack of full understanding of the ligands recognized by TCR-γδ and how expression of these ligands is regulated. We recently developed a soluble human TCR-γδ (Vγ9Vδ1) tetramer from a synovial γδ T cell clone of a Lyme arthritis patient and observed that it stains monocytes activated by Borrelia burgdorferi. Those findings are extended in the current study to further examine the physiological regulation of ligand expression on monocytes. The TC...
Friday 9 June 2023
As spring blooms across much of the state, University of Arizona researchers are encouraging the public to check for ticks and contribute to an important community health effort. Rosemary Brandt Today College of Agriculture& Life SciencesRhipicephalussanguineus_hires-small.jpg A male brown dog tick, Rhipicephalus sanguineus. Brown dog ticks are the primary vector for Rocky Mountain spotted fever in Arizona. CDC/ James GathanyHealthScience and TechnologyCollege of Agriculture and Life SciencesCollege of Public Health Media contact(s)Rosemary Brandt College of Agriculture and Life Sciencesrjbrandt@email.arizona.edu520-358-9729How to remove a tickIf you find a tick attached to your skin, don't panic. Simply remove the tick as soon as possible.Using clean, fine-tipped tweezers, g...
Friday 9 June 2023
Oman Med J. 2022 Nov 30;37(6):e446. doi: 10.5001/omj.2022.31. eCollection 2022 Nov.NO ABSTRACTPMID:36458239 | PMC:PMC9644041 | DOI:10.5001/omj.2022.31 (Source: Oman Medical Journal)
Friday 9 June 2023
Vector-Borne and Zoonotic Diseases, Ahead of Print. (Source: Vector-Borne and Zoonotic Diseases)
Friday 9 June 2023
Contributors : Jenny Wachter ; Patti RosaSeries Type : Expression profiling by high throughput sequencingOrganism : Borreliella burgdorferi B31Lyme disease spirochetes must induce RpoS-dependent genes during tick feeding to prepare for host infection. Previous work in our lab identified bbd18 as a negative regulator of RpoS, but inactivation of bbd18 in wild-type spirochetes was never achieved. In the current study we generated an inducible bbd18 gene at the endogenous plasmid locus and demonstrated the essential nature of BBD18 for viability of wild-type spirochetes in vitro and at a unique point in vivo. Transcriptomic analyses demonstrated global induction of RpoS and RpoS-dependent genes following BBD18 depletion, culminating in spirochete lysis. Plasmid prophage genes were also induce...
Friday 9 June 2023
Emerg Infect Dis. 2023 Apr;29(4):701-710. doi: 10.3201/eid2904.221572.ABSTRACTMonitoring of tickborne diseases is critical for prevention and management. We analyzed 418 ticks removed from 359 patients during 2014-2021 in Marseille, France, for identification and bacteria detection. Using morphology, molecular methods, or matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, we identified 197 (47%) Ixodes, 136 (33%) Dermacentor, 67 (16%) Rhipicephalus, 8 (2%) Hyalomma, 6 (1%) Amblyomma, 2 (0.5%) Argas, and 2 (0.5%) Haemaphysalis tick species. We also detected bacterial DNA in 241 (58%) ticks. The most frequent bacterial pathogens were Rickettsia raoultii (17%) and R. slovaca (13%) in Dermacentor ticks, Borrelia spp. (9%) in Ixodes ticks, and R. massiliae (16%) in Rh...
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Friday 9 June 2023
Trends Parasitol. 2023 Mar 22:S1471-4922(23)00071-5. doi: 10.1016/j.pt.2023.03.010. Online ahead of print.ABSTRACTCross-species communication drives the coordination of diverse biological processes in complex systems. Rana et al. discovered that Ixodes scapularis, the tick vector of Lyme disease, produces a receptor that binds host interferon-gamma (IFNγ) in the blood meal, which orchestrates tick development, immunity, and vector competence.PMID:36958955 | DOI:10.1016/j.pt.2023.03.010 (Source: Trends in Parasitology)
Friday 9 June 2023
Study of Lyme Immunology and Clinical Events (SLICE) (study page |release notes) (Source: dbGaP, the database of Genotypes and Phenotypes)
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Friday 9 June 2023
Emerg Infect Dis. 2023 Apr;29(4):701-710. doi: 10.3201/eid2904.221572.ABSTRACTMonitoring of tickborne diseases is critical for prevention and management. We analyzed 418 ticks removed from 359 patients during 2014-2021 in Marseille, France, for identification and bacteria detection. Using morphology, molecular methods, or matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, we identified 197 (47%) Ixodes, 136 (33%) Dermacentor, 67 (16%) Rhipicephalus, 8 (2%) Hyalomma, 6 (1%) Amblyomma, 2 (0.5%) Argas, and 2 (0.5%) Haemaphysalis tick species. We also detected bacterial DNA in 241 (58%) ticks. The most frequent bacterial pathogens were Rickettsia raoultii (17%) and R. slovaca (13%) in Dermacentor ticks, Borrelia spp. (9%) in Ixodes ticks, and R. massiliae (16%) in Rh...
Friday 9 June 2023
We report isolation and whole-genome nucleotide sequencing of a B. garinii isolate from a cotton mouse (Peromyscus gossypinus) in South Carolina, USA. We identified a second B. garinii isolate from the same repository. Phylogenetic analysis does not associate these isolates with the previously described isolates of B. garinii from Canada.PMID:36573553 | DOI:10.3201/eid2901.220930 (Source: Emerging Infectious Diseases)
Friday 9 June 2023
Trends Parasitol. 2023 Mar 22:S1471-4922(23)00071-5. doi: 10.1016/j.pt.2023.03.010. Online ahead of print.ABSTRACTCross-species communication drives the coordination of diverse biological processes in complex systems. Rana et al. discovered that Ixodes scapularis, the tick vector of Lyme disease, produces a receptor that binds host interferon-gamma (IFNγ) in the blood meal, which orchestrates tick development, immunity, and vector competence.PMID:36958955 | DOI:10.1016/j.pt.2023.03.010 (Source: Trends in Parasitology)
Friday 9 June 2023
We report isolation and whole-genome nucleotide sequencing of a B. garinii isolate from a cotton mouse (Peromyscus gossypinus) in South Carolina, USA. We identified a second B. garinii isolate from the same repository. Phylogenetic analysis does not associate these isolates with the previously described isolates of B. garinii from Canada.PMID:36573553 | DOI:10.3201/eid2901.220930 (Source: Emerging Infectious Diseases)
Friday 9 June 2023
To identify the multilocus sequence typing (MLST) sequence types of Borrelia burgdorferi from Ixodes scapularis in Ontario, Canada. (Source: BMC Research Notes)
Friday 9 June 2023
We report isolation and whole-genome nucleotide sequencing of a B. garinii isolate from a cotton mouse (Peromyscus gossypinus) in South Carolina, USA. We identified a second B. garinii isolate from the same repository. Phylogenetic analysis does not associate these isolates with the previously described isolates of B. garinii from Canada.PMID:36573553 | DOI:10.3201/eid2901.220930 (Source: Emerging Infectious Diseases)
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Friday 9 June 2023
CONCLUSIONS: In the current study, most children with Lyme disease experienced full resolution of symptoms, including those who initially met PTLD syndrome criteria. Effective communication about recovery rates and common symptoms that may persist post-treatment is needed.IMPACT: The majority of pediatric patients treated for all stages of Lyme disease reported full resolution of symptoms within 6 months. 22% of pediatric patients reported one or more symptom persisting >6 months, 9% with and 13% without accompanying functional impairment. Effective communication with families about recovery rates and common symptoms that may persist post-treatment of Lyme disease is needed.PMID:36997691 | DOI:10.1038/s41390-023-02577-3 (Source: Pediatric Research)
Friday 9 June 2023
We report isolation and whole-genome nucleotide sequencing of a B. garinii isolate from a cotton mouse (Peromyscus gossypinus) in South Carolina, USA. We identified a second B. garinii isolate from the same repository. Phylogenetic analysis does not associate these isolates with the previously described isolates of B. garinii from Canada.PMID:36573553 | DOI:10.3201/eid2901.220930 (Source: Emerging Infectious Diseases)
Friday 9 June 2023
We present a case of fulminant myocarditis following a tick bite which highlights this diagnostic challenge. (Source: The Journal of Heart and Lung Transplantation)
Friday 9 June 2023
We report isolation and whole-genome nucleotide sequencing of a B. garinii isolate from a cotton mouse (Peromyscus gossypinus) in South Carolina, USA. We identified a second B. garinii isolate from the same repository. Phylogenetic analysis does not associate these isolates with the previously described isolates of B. garinii from Canada.PMID:36573553 | DOI:10.3201/eid2901.220930 (Source: Emerging Infectious Diseases)
Friday 9 June 2023
ConclusionWe present a national level spatial assessment of seasonal LB occurrence in Europe, disentangling factors associated with the presence and increased incidence of LB. Our findings yield quantitative evidence for national public health agencies to plan targeted prevention campaigns to reduce LB burden, enhance surveillance and identify further data needs. This approach can be tested in other LB endemic areas.PMID:37022210 | DOI:10.2807/1560-7917.ES.2023.28.14.2200581 (Source: Euro Surveill)
Friday 9 June 2023
Conclusion: In a Lyme-endemic area in the Netherlands, LNB commonly presents with facial nerve palsy. Facial nerve palsy and headache are more prevalent in children, while radiculitis and encephalitis are mostly reported in adults.What is Known:• The clinical course of Lyme neuroborreliosis in adults is often different from children..• The aim of this study was to compare the clinical characteristics and outcome of LNB between children and adults.What is New:• Lyme neuroborreliosis in the Netherlands commonly presents with facial nerve palsy.• Facial nerve palsy and headache are more prevalent in children than in adults. Radiculitis and encephalitis are mostly reported in adults. (Source: European Journal of Pediatrics)
Friday 9 June 2023
AbstractAnimal ectoparasites are linked to the spread of serious medical and veterinary important pathogens. Our research intends to close the knowledge gap concerning the numerous ectoparasites that inhabit animals in Wayanad. Ectoparasites in animals brought to the veterinary dispensaries in Wayanad were retrieved and identified morphologically and molecularly. Using a high-quality stereomicroscope, the taxonomic features of the four following species were examined and identified: Haemaphysalis bispinosa,Rhipicephalus annulatus, R. microplus, andAmblyomma geoemydae. The important disease vectorA. geoemydae was reported for the first time in Kerala. The important phenotypic characters of the highlighted speciesA. geoemydae are the edge of the basis capituli is circular without cornua, and...
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Friday 9 June 2023
Vector-Borne and Zoonotic Diseases, Ahead of Print. (Source: Vector-Borne and Zoonotic Diseases)
Friday 9 June 2023
Lyme disease (LD), the most prevalent tick-borne disease of humans in the Northern Hemisphere, is caused by the spirochetal bacterium of Borreliella burgdorferi (Bb) sensu lato complex. In nature, Bb spirochetes are continuously transmitted between Ixodes ticks and mammalian or avian reservoir hosts. Peromyscus leucopus mice are considered the primary mammalian reservoir of Bb in the United States. Earlier studies demonstrated that experimentally infected P. leucopus mice do not develop disease. In contrast, C3H mice, a widely used laboratory strain of Mus musculus in the LD field, develop severe Lyme arthritis. To date, the exact tolerance mechanism of P. leucopus mice to Bb-induced infection remains unknown. To address this knowledge gap, the present study has compared spleen transcripto...
Friday 9 June 2023
Lyme neuroborreliosis, caused by the bacterium Borrelia burgdorferi affects both the central and peripheral nervous systems (CNS, PNS). The CNS manifestations, especially at later stages, can mimic/cause many oth... (Source: Journal of Neuroinflammation)
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Friday 9 June 2023
CONCLUSION: These results show a first picture of the microbial diversity of ticks and highlight the importance of microbiota and their role in host-pathogen interaction.PMID:37038504 | PMC:PMC10082412 | DOI:10.18502/jad.v16i2.11801 (Source: Iranian Journal of Arthropod-Borne Diseases)
Friday 9 June 2023
Conclusions: These findings support the idea that, as one of many factors, the contact with spirochetal antigens may indicate a potential positive correlation with the formation of cardiovascular changes. More research, not only at the diagnostic level but also at the advanced research level, is needed. (Source: International Journal of Environmental Research and Public Health)
Friday 9 June 2023
Vector-Borne and Zoonotic Diseases,Volume 23, Issue 4, Page 139-141, April 2023. (Source: Vector-Borne and Zoonotic Diseases)
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Friday 9 June 2023
ConclusionPatients with antibiotic-responsive LA hadBb-IgG1 antibodies with more balanced pro-inflammatory/anti-inflammatory glycan profiles, whereas patients with antibiotic-refractory LA hadBb-IgG1 antibodies with maximal, minimally opposed, pro-inflammatory glycan profiles. Among patients with antibiotic refractory LA, antibodies with this unbalanced inflammatory glycan profile may play a role in sustaining maladaptive joint inflammation.This article is protected by copyright. All rights reserved. (Source: Arthritis and Rheumatology)
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Friday 9 June 2023
Vector-Borne and Zoonotic Diseases,Volume 23, Issue 4, Page 137-138, April 2023. (Source: Vector-Borne and Zoonotic Diseases)
Friday 9 June 2023
Am J Trop Med Hyg. 2023 Feb 6:tpmd220437. doi: 10.4269/ajtmh.22-0437. Online ahead of print.ABSTRACTThe erythema migrans (EM) rash is an important initial diagnostic sign of early Lyme disease. We tested the hypothesis that patients who noticed EM first differed from those who noticed viral-like symptoms first. "EM First" participants (167/271, 61.6%) had shorter illness duration before treatment (5.0 versus 6.2 days, P = 0.019), were more likely to have seen or removed a tick (P = 0.048) and to be non-Hispanic White (P = 0.025), and were less likely to present with disseminated lesions at the time of diagnosis (P = 0.003) than "Symptoms First" participants (104/271, 38.4%). In multivariate analyses, EM First participants had a 22% decrease in time to treatment (P = 0.012) compared with Sy...
Friday 9 June 2023
Vector-Borne and Zoonotic Diseases,Volume 23, Issue 4, Page 142-155, April 2023. (Source: Vector-Borne and Zoonotic Diseases)
Friday 9 June 2023
In this study, low-dose methylprednisolone (0.8 mg/kg/day, MP) was used to induce a steroid-resistant lupus nephritis (SR-LN) mouse model in weeks one to four, and a therapeutic steroid dosage (MP 12 mg/kg/day) or a combined PNS (PNS 100 mg/kg/day) treatment was administered from week five to eight. Lymphocyte-derived exosomes (Lyme-Exos) were isolated from the spleens of mice and injected into untreated homozygous LN mice for 14 days via the tail vein. At the end of the experiment, the efficacy and mechanism of action of different groups of Lyme-Exos on LN mice were observed. The results revealed that exogenously injected Lyme-Exos were effectively taken up by the kidney and affected the progression of kidney disease. Steroid-resistant lymphocyte-derived exosomes intervented with PNS ...
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Friday 9 June 2023
Vector-Borne and Zoonotic Diseases,Volume 23, Issue 4, Page 156-171, April 2023. (Source: Vector-Borne and Zoonotic Diseases)
Friday 9 June 2023
Clin Microbiol Rev. 2022 Oct 12:e0007422. doi: 10.1128/cmr.00074-22. Online ahead of print.ABSTRACTLyme borreliosis is caused by spirochetes belonging to the Borrelia burgdorferi sensu lato group, which are transmitted by Ixodes tick species living in the temperate climate zones of the Northern Hemisphere. The clinical manifestations of Lyme borreliosis are diverse and treated with oral or intravenous antibiotics. In some patients, long-lasting and debilitating symptoms can persist after the recommended antibiotic treatment. The etiology of such persisting symptoms is under debate, and one hypothesis entails persistent infection by a subset of spirochetes after antibiotic therapy. Here, we review and appraise the experimental evidence from in vivo animal studies on the persistence of B. bu...
Friday 9 June 2023
Vector-Borne and Zoonotic Diseases,Volume 23, Issue 4, Page 172-194, April 2023. (Source: Vector-Borne and Zoonotic Diseases)
Friday 9 June 2023
Lyme disease (LD), the leading tick-borne disease in the Northern hemisphere, is caused by spirochetes of several genospecies of the Borreliella burgdorferi sensu lato complex. LD is a multi-systemic and highly debilitating illness that is notoriously challenging to diagnose. The main drawbacks of the two-tiered serology, the only approved diagnostic test in the United States, include poor sensitivity, background seropositivity, and cross-reactivity. Recently, Raman spectroscopy (RS) was examined for its LD diagnostic utility by our earlier proof-of-concept study. The previous investigation analyzed the blood from mice that were infected with 297 and B31 strains of Borreliella burgdorferi sensu stricto (s.s.). The selected strains represented two out of the three major clades of B. burgdor...
Friday 9 June 2023
Vector-Borne and Zoonotic Diseases,Volume 23, Issue 4, Page 195-220, April 2023. (Source: Vector-Borne and Zoonotic Diseases)
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Friday 9 June 2023
Tex Heart Inst J. 2022 Sep 1;49(5):e217777. doi: 10.14503/THIJ-21-7777.NO ABSTRACTPMID:36315845 | DOI:10.14503/THIJ-21-7777 (Source: Texas Heart Institute Journal)
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Friday 9 June 2023
Vector-Borne and Zoonotic Diseases,Volume 23, Issue 4, Page 221-229, April 2023. (Source: Vector-Borne and Zoonotic Diseases)
Friday 9 June 2023
Tex Heart Inst J. 2022 Sep 1;49(5):e217777. doi: 10.14503/THIJ-21-7777.NO ABSTRACTPMID:36315845 | DOI:10.14503/THIJ-21-7777 (Source: Texas Heart Institute Journal)
Friday 9 June 2023
Vector-Borne and Zoonotic Diseases,Volume 23, Issue 4, Page 230-236, April 2023. (Source: Vector-Borne and Zoonotic Diseases)
Friday 9 June 2023
Ixodes scapularis is one of the predominant vectors of Borrelia burgdorferi, the agent of Lyme disease in the USA. The geographic distribution of I. scapularis, endemic to the northeastern and northcentral USA, is expanding as far south as Georgia and Texas, and northwards into Canada and poses an impending public health problem. The prevalence and spread of tick-borne diseases are influenced by the interplay of multiple factors including microbiological, ecological, and environmental. Molecular studies have focused on interactions between the tick-host and pathogen/s that determine the success of pathogen acquisition by the tick and transmission to the mammalian host. In this review we draw attention to additional critical environmental factors that impact tick biology and tick-pathogen i...
Friday 9 June 2023
Vector-Borne and Zoonotic Diseases,Volume 23, Issue 4, Page 237-246, April 2023. (Source: Vector-Borne and Zoonotic Diseases)
Friday 9 June 2023
Vaccine. 2022 Nov 8:S0264-410X(22)01292-0. doi: 10.1016/j.vaccine.2022.10.032. Online ahead of print.ABSTRACTIxodes ricinus and Ixodes scapularis are the main vectors for the causative agents of Lyme borreliosis and a wide range of other pathogens. Repeated tick-bites are known to lead to tick rejection; a phenomenon designated as tick immunity. Tick immunity is mainly directed against tick salivary gland proteins (TSGPs) and has been shown to partially protect against experimental Lyme borreliosis. TSGPs recognized by antibodies from tick immune animals could therefore be interesting candidates for an anti-tick vaccine, which might also block pathogen transmission. To identify conserved Ixodes TSGPs that could serve as a universal anti-tick vaccine in both Europe and the US, a Yeast Surfa...
Friday 9 June 2023
Vector-Borne and Zoonotic Diseases,Volume 23, Issue 4, Page 247-255, April 2023. (Source: Vector-Borne and Zoonotic Diseases)
Friday 9 June 2023
Conclusion In this cohort, there was a large number of VN patients with infectious signs; several patients tested positive for HSV and LD. Therefore we recommend testing VN patients not only for HSV but also for LD and other neurotropic viruses. This approach enables to complement the standard VN treatment with a specific treatment.PMID:36381739 | PMC:PMC9635860 | DOI:10.7759/cureus.29959 (Source: Herpes)
Friday 9 June 2023
Vector-Borne and Zoonotic Diseases,Volume 23, Issue 4, Page 265-272, April 2023. (Source: Vector-Borne and Zoonotic Diseases)
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Friday 9 June 2023
This article reviews uncommon bacterial (brucellosis, actinomycosis, neuromelioidosis, nocardiosis, whipple disease, and listeriosis), Rickettsia, spirochete (neurosyphilis and Lyme disease), and fungal (mucormycosis, aspergillosis, candidiasis, cryptococcosis, and Cladophialophora bantiana) diseases affecting central nervous system (CNS), focusing primarily on their cranial manifestations. These infections often show a variety of neuroimaging features that may be similar or differ from typical pyogenic bacterial meningitis and abscess. Familiarity with these patterns is essential for timely recognition and initiation of appropriate management. Neuroimaging is also useful for identifying complications of CNS infections and follow-up evaluation after initiation of treatment. (Source: Neuroi...
Friday 9 June 2023
Vector-Borne and Zoonotic Diseases,Volume 23, Issue 4, Page 256-264, April 2023. (Source: Vector-Borne and Zoonotic Diseases)
Friday 9 June 2023
This study revealed that for Lyme Disease, one or two SOT administrations can lead to a statistically significant decrease in DNA copies, while for viruses, two or three administrations are required to achieve a statistically significant reduction in the genetic material. These preliminary results indicate that antisense SOT therapy can be considered a potential treatment for viral as well as Lyme diseases.PMID:36412742 | DOI:10.3390/idr14060084 (Source: Herpes)
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Friday 9 June 2023
Lyme disease is one of the most common vector-borne illnesses in the United States. It is caused by Borrelia burgdorferi infection transmitted via the Ixodes tick. Rarely, it can progress to early disseminated Lyme disease with cardiac or neurologic manifestations, or both. (Source: The Journal of Emergency Medicine)
Friday 9 June 2023
by Constantin N. Takacs, Yuko Nakajima, James E. Haber, Christine Jacobs-Wagner The spirocheteBorrelia burgdorferi, which causes Lyme disease, has the most segmented genome among known bacteria. In addition to a linear chromosome, theB.burgdorferi genome contains over 20 linear and circular endogenous plasmids. While many of these plasmids are dispensable under in vitro culture conditions, they are maintained during the natural life cycle of the pathogen. Plasmid-encoded functions are required for colonization of the tick vector, transmission to the vertebrate host, and evasion of host immune defenses. DifferentBorrelia strains can vary substantially in the type of plasmids they carry. The gene composition within the same type of plasmid can also differ from strain to strain, impeding the...
Friday 9 June 2023
Systematic assessments of the presence and severity of particular symptoms over time are relatively uncommon for Lyme disease patients in the United States, and especially for Lyme disease patients with extracutaneous manifestations (ECLD). (Source: The American Journal of Medicine)
Friday 9 June 2023
Advancement in proteomics methods for interrogating biological samples has helped identify disease biomarkers for early diagnostics and unravel underlying molecular mechanisms of disease. Herein, we examined the serum proteomes of 23 study participants presenting with one of two common arthropod-borne infections: Lyme disease (LD), an extracellular bacterial infection or West Nile virus infection (WNV), an intracellular viral infection. The LC/MS based serum proteomes of samples collected at the time of diagnosis and during convalescence were assessed using a depletion-based high-throughput shotgun proteomics (dHSP) pipeline as well as a non-depleting blotting-based low-throughput platform (MStern). The LC/MS integrated analyses identified host proteome responses in the acute and recovery ...
Friday 9 June 2023
Lyme disease is one of the most common vector-borne illnesses in the United States. It is caused by Borrelia burgdorferi infection transmitted via the Ixodes tick. Rarely it can progress to early disseminated Lyme disease with cardiac and/or neurologic manifestations. (Source: The Journal of Emergency Medicine)
Friday 9 June 2023
Ticks infected with the bacterium responsible for Lyme disease are more likely to survive winter, contributing to the spread of the disease as the world warms (Source: New Scientist - Health)
Friday 9 June 2023
In this study, we examined whether intracellular nucleic acid sensing is required for the induction of IFN-I to B. burgdorferi. Using fluorescence microscopy, we show that B. burgdorferi associates with mouse and human cells in culture, and we document that internalized spirochetes colocalize with the pattern recognition receptor cyclic GMP-AMP synthase (cGAS). Moreover, we report that IFN-I responses in mouse macrophages and murine embryonic fibroblasts are significantly attenuated in the absence of cGAS or its adaptor stimulator of IFN genes (STING), which function to sense and respond to intracellular DNA. Longitudinal in vivo tracking of bioluminescent B. burgdorferi revealed similar dissemination kinetics and borrelial load in C57BL/6J wild-type, cGAS-deficient, or STING-deficient mic...
Friday 9 June 2023
Ann Allergy Asthma Immunol. 2022 Dec 24:S1081-1206(22)02010-5. doi: 10.1016/j.anai.2022.12.025. Online ahead of print.ABSTRACTIn this paper, we discuss pertinent cutaneous findings that patients may present following travel to tropical destinations. We address arthropod-borne infectious diseases such as Cutaneous Leishmaniasis, Chagas Disease, Cutaneous Larvae Migrans, Myiasis, and others. We discuss other relevant diseases with cutaneous signs such as Monkey Pox and SARS-CoV-2. We provide clinicians with information regarding the background, diagnosis, treatment, and prevention of these tropical rashes. Additionally, we address the impact that climate change will have on the temporal and geographic incidence of these rashes. Viral, fungal, and vector-borne diseases have seen a geographic ...
Friday 9 June 2023
Infection of C3H/HeJ (C3H) mice with Borrelia burgdorferi results in the development of a robust inflammatory arthritis that peaks around 3-4 weeks post-infection and then spontaneously resolves over the next few weeks. Mice lacking cyclooxygenase (COX)-2 or 5-lipoxygenase (5-LO) activity develop arthritis similar to wild-type mice but display delayed or prolonged joint resolution. Since 12/15-lipoxygenase (12/15-LO) activity is generally down-stream of both COX-2 and 5-LO activity and results in the production of pro-resolution lipids such as lipoxins and resolvins among others, we investigated the impact of 12/15-LO deficiency on the resolution of Lyme arthritis in mice on a C3H background. We found the expression of Alox15 (12/15-LO gene) peaked around 4-weeks post-infection in C3H mice...
Friday 9 June 2023
Ann Allergy Asthma Immunol. 2022 Dec 24:S1081-1206(22)02010-5. doi: 10.1016/j.anai.2022.12.025. Online ahead of print.ABSTRACTIn this paper, we discuss pertinent cutaneous findings that patients may present following travel to tropical destinations. We address arthropod-borne infectious diseases such as Cutaneous Leishmaniasis, Chagas Disease, Cutaneous Larvae Migrans, Myiasis, and others. We discuss other relevant diseases with cutaneous signs such as Monkey Pox and SARS-CoV-2. We provide clinicians with information regarding the background, diagnosis, treatment, and prevention of these tropical rashes. Additionally, we address the impact that climate change will have on the temporal and geographic incidence of these rashes. Viral, fungal, and vector-borne diseases have seen a geographic ...
Friday 9 June 2023
J Microbiol Biotechnol. 2023 Mar 10;33(6):1-9. doi: 10.4014/jmb.2212.12010. Online ahead of print.ABSTRACTMicrobial biofilms are resilient, immune-evasive, and often antibiotic-resistant health challenges, and increasingly the target for research into novel therapeutic strategies. We evaluated the effects of a nutraceutical enzyme and botanical blend (NEBB) on established biofilm. Five microbial strains with known implications in chronic human illnesses were tested: Candida albicans, Staphylococcus aureus, Staphylococcus simulans (coagulase-negative, penicillin-resistant), Borrelia burgdorferi, and Pseudomonas aeruginosa. The strains were allowed to form biofilm in vitro. Biofilm cultures were treated with NEBB containing enzymes targeted at lipids, proteins, and sugars, also containing th...
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Friday 9 June 2023
CONCLUSION: Tick-borne disease is popular among EMRO countries, indicating that they have natural conditions for infections in animals and humans. It appears necessary to develop a disease management strategy and control programs against tick-borne diseases (TBDs). Moreover, the disease-resistant animal could be bred instead of susceptible livestock. Therefore, research studies to control TBDs should be regarded as a top priority plan.PMID:36578998 | PMC:PMC9759441 | DOI:10.18502/jad.v15i3.9814 (Source: Iranian Journal of Arthropod-Borne Diseases)
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Friday 9 June 2023
CONCLUSION: This type of in-silico technique may precisely decrease valuable time and expenses in vaccine designing against Borrelia burgdorferi for experimental planning in laboratories. Currently, scientists frequently utilize bioinformatics approaches that speed up their vaccine-based lab work.PMID:37073655 | DOI:10.2174/1381612829666230418104520 (Source: Current Pharmaceutical Design)
Friday 9 June 2023
This study aims to evaluate the effi... (Source: BMC Infectious Diseases)
Friday 9 June 2023
The early diagnosis and detection of tick-borne infection (TI), including Lyme disease, remains a challenge [1]. Because tick-borne disease is “the great mimicker”, symptoms often appear similar to other systemic and neurological conditions, causing the correct diagnosis to be missed or delayed [1]. The lack of diagnosis and treatment in the acute phase may result in a chronic and even neurological advancement in the undiagnosed diseas e. (Source: International Journal of Infectious Diseases)
Friday 9 June 2023
CONCLUSIONS: The appropriate management of this patient was made possible by the combination of multimodal imaging and appropriate laboratory tests, representing the optimal process in the diagnostic and therapeutic pathway in high-risk patients for ocular Lyme disease.PMID:36710514 | DOI:10.1177/11206721231154172 (Source: European Journal of Ophthalmology)
Friday 9 June 2023
The early diagnosis and detection of tick-borne infection (TI), including Lyme disease, remains a challenge.[1] Since tick-borne disease is “The Great Mimicker,” symptoms often appearing similar to other systemic and neurological conditions causing the correct diagnosis to be missed or delayed.[1] Lack of diagnosis and treatment in the acute phase may result in a chronic and even neurological advancement in the undiagnosed disease. (Source: International Journal of Infectious Diseases)
Friday 9 June 2023
Because patients with a “suspicion of Lyme borreliosis (LB)” may experience medical wandering and difficult care paths, often due to misinformation, multidisciplinary care centers were started all over Europe ... (Source: BMC Infectious Diseases)
Friday 9 June 2023
Without prompt diagnosis and treatment, patients with Lyme disease may develop life threatening multi-organ system complications. As such, we discuss the key diagnostic features of the condition along with patient-specific suggested treatment protocols. Additionally, Lyme disease is reportedly expanding to regions that were previously not impacted, key epidemiological features are outlined. We discuss a patient with severe Lyme disease who presented with widespread cutaneous involvement and atypical pathologic findings within an uncharacteristic geographic region. Erythematous, annular patches and plaques with dusky-to-clear centers were initially observed on the right thigh and later extended to the trunk and bilateral lower extremities. The diagnosis of Lyme disease was made clinically a...
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Friday 9 June 2023
Trends Microbiol. 2022 Oct 13:S0966-842X(22)00256-6. doi: 10.1016/j.tim.2022.09.010. Online ahead of print.ABSTRACTSpirochaetes, a phylum that includes medically important pathogens such as the causative agents of Lyme disease, syphilis, and leptospirosis, are in many ways highly unique bacteria. Their cell morphology, subcellular organization, and metabolism reveal atypical features. Spirochetal motility is also singular, dependent on the presence of periplasmic flagella or endoflagella, inserted subterminally at cell poles and not penetrating the outer membrane and elongating outside the cell as in enterobacteria. In this review we present a comprehensive comparative genomics analysis of endoflagellar systems in spirochetes, highlighting recent findings on the flagellar basal body and fi...
Friday 9 June 2023
Lyme disease is the most common tick-borne disease and is caused by a group of bacteria known as Borrelia burgdorferi sensu lato (s.l.) complex. Sharing the same genus as B. burgdorferi, Borrelia miyamotoi is a distinct genotype that causes relapsing fever disease. This emerging tick-borne disease is increasingly becoming a concern in public health. To investigate the prevalence of B. burgdorferi s.l. and B. miyamotoi in ticks first, we developed a PCR (Bmer-qPCR) that targets the phage terminase large subunit (terL) gene carried by B. miyamotoi. A similar approach had been used successfully in developing Ter-qPCR for detecting B. burgdorferi s.l. The terL protein functions as an enzyme in packaging phage DNA. Analytical validation of the Bmer-qPCR confirmed its specificity, efficiency and...
Friday 9 June 2023
Tex Heart Inst J. 2022 Sep 1;49(5):e217777. doi: 10.14503/THIJ-21-7777.NO ABSTRACTPMID:36315845 | DOI:10.14503/THIJ-21-7777 (Source: Texas Heart Institute Journal)
Friday 9 June 2023
Lyme carditis occurs in 1.5%-10% untreated patients infected with Borrelia burgdorferi in United States and usually manifests as varying degrees of atrioventricular (AV) block, myopericarditis, and degenerative valve disease. Several cases of junctional tachycardia have been reported in children with Lyme disease, but there have not been any cases reported in the adult population. Here, we report a case of accelerated junctional tachycardia in a 42-year-old woman with Lyme carditis. (Source: Heart Rhythm)
Friday 9 June 2023
Contributors : Anne L Sapiro ; Beth Hayes ; Seemay ChouSeries Type : Expression profiling by high throughput sequencingOrganism : Borreliella burgdorferiBorrelia burgdorferi, the causative agent of Lyme disease, is transmitted to vertebrate hosts by Ixodes ticks. As it moves from tick to host, B. burgdorferi must adapt to survive in a vastly different environment. During the tick bloodmeal, which lasts several days, B. burgdorferi is primed for mammalian infection, growing increasingly virulent as it senses cues from its surroundings in the tick. This conditioning is dependent on key transcriptional regulators; however, the downstream transcriptional changes occurring inside of the tick that promote B. burgdorferi transmission and infection are poorly understood due to technical difficulti...
Friday 9 June 2023
Lyme neuroborreliosis (LNB), due to infection of the nervous system by the spirochete Borrelia burgdorferi, occurs in 15% of Lyme disease cases. However, neurovascular involvement is uncommon, especially recurren... (Source: BMC Infectious Diseases)
Friday 9 June 2023
Clin Immunol. 2022 Nov 14:109180. doi: 10.1016/j.clim.2022.109180. Online ahead of print.ABSTRACTBorrelia burgdorferi (Bb) infection causes Lyme disease, for which there is need for more effective therapies. Here, we sequenced the antibody repertoire of plasmablasts in Bb-infected humans. We expressed recombinant monoclonal antibodies (mAbs) representing the identified plasmablast clonal families, and identified their binding specificities. Our recombinant anti-Bb mAbs exhibit a range of activity in mediating macrophage phagocytosis of Bb. To determine if we could increase the macrophage phagocytosis-promoting activity of our anti-Bb mAbs, we generated a TLR9-agonist CpG-oligo-conjugated anti-BmpA mAb. We demonstrated that our CpG-conjugated anti-BmpA mAb exhibited increased peak Bb phagoc...
Friday 9 June 2023
We demonstrate that adult ticks (Ixodes scapularis) infected withBorrelia burgdorferi, the bacterium that causes Lyme Disease, have greater overwintering survival than uninfected ticks.Adult ticks were placed in individual microcosms and allowed to overwinter. In the spring we collected the ticks and tested both dead and living ticks forB. burgdorferi DNA. We also performed lab tests to show that we could accurately identifyB. burgdorferi DNA in ticks 10 weeks after their death. The study was repeated over 3 years, and infected ticks were more likely to survive the winter than uninfected ticks in each of the 3 winters in two different microclimates (i.e., dune grass and forest). Increased overwintering survival of infected ticks will lead to an enrichment of infected adult ticks in the ear...
Friday 9 June 2023
Emerg Infect Dis. 2022 Dec;28(12):2389-2397. doi: 10.3201/eid2812.212612.ABSTRACTSince its initial identification in 1986, Lyme disease has been clinically diagnosed in 29 provinces in China; however, national incidence data are lacking. To summarize Lyme disease seropositivity data among persons across China, we conducted a systematic literature review of Chinese- and English-language journal articles published during 2005‒2020. According to 72 estimates that measured IgG by using a diagnostic enzyme-linked assay (EIA) alone, the seropositivity point prevalence with a fixed-effects model was 9.1%. A more conservative 2-tier testing approach of EIA plus a confirmatory Western immunoblot (16 estimates) yielded seropositivity 1.8%. Seropositivity by EIA for high-risk exposure populations w...
Friday 9 June 2023
S. A. Hern ández et al. (Source: Emerging Infectious Diseases Journal)
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Friday 9 June 2023
J R Coll Physicians Edinb. 2022 Dec 15:14782715221144167. doi: 10.1177/14782715221144167. Online ahead of print.NO ABSTRACTPMID:36519641 | DOI:10.1177/14782715221144167 (Source: Journal of the Royal College of Physicians of Edinburgh)
Friday 9 June 2023
ConclusionPatients with oral antibiotic –responsive LA had Bb IgG1 antibodies with more balanced proinflammatory/antiinflammatory glycan profiles, whereas patients with antibiotic-refractory LA had Bb IgG1 antibodies with maximal, minimally opposed, proinflammatory glycan profiles. Among patients with antibiotic-refractory LA, antibodie s with this unbalanced inflammatory glycan profile may have a role in sustaining maladaptive joint inflammation. (Source: Arthritis and Rheumatology)
Friday 9 June 2023
Ann Allergy Asthma Immunol. 2022 Dec 24:S1081-1206(22)02010-5. doi: 10.1016/j.anai.2022.12.025. Online ahead of print.ABSTRACTIn this paper, we discuss pertinent cutaneous findings that patients may present following travel to tropical destinations. We address arthropod-borne infectious diseases such as Cutaneous Leishmaniasis, Chagas Disease, Cutaneous Larvae Migrans, Myiasis, and others. We discuss other relevant diseases with cutaneous signs such as Monkey Pox and SARS-CoV-2. We provide clinicians with information regarding the background, diagnosis, treatment, and prevention of these tropical rashes. Additionally, we address the impact that climate change will have on the temporal and geographic incidence of these rashes. Viral, fungal, and vector-borne diseases have seen a geographic ...
Friday 9 June 2023
CONCLUSION: Reactivation of latent herpes virus has been suggested as one of the possible mechanisms underlying the phenomenon, but the causal pathophysiology related to the symptom needs further validation. Moreover, in the event of facial palsy post-vaccination, alternative diagnoses such as Guillain-Barre syndrome (GBS), Ramsey-Hunt syndrome, Lyme disease, trauma, central nervous system infection (CNS) infection, or stroke should also be considered.PMID:37198509 (Source: Acta Neurologica Taiwanica)
Friday 9 June 2023
The genus Borrelia is composed of two well-defined monophyletic groups, the Borrelia burgdorferi sensu lato complex (Bb) and the relapsing fever (RF) group borreliae. Recently, a third group, associated with rept... (Source: Parasites and Vectors)
Friday 9 June 2023
Pediatr Res. 2023 May 18. doi: 10.1038/s41390-023-02661-8. Online ahead of print.NO ABSTRACTPMID:37202531 | DOI:10.1038/s41390-023-02661-8 (Source: Pediatric Research)
Friday 9 June 2023
Infection and Immunity, Ahead of Print. (Source: Infection and Immunity)
Friday 9 June 2023
Ocul Immunol Inflamm. 2023 May 19:1-8. doi: 10.1080/09273948.2023.2211161. Online ahead of print.ABSTRACTA group of self-limiting and frequently neglected diseases exist in the literature like Rickettsial disease, Malaria, Dengue fever, Chikungunya, West Nile virus infection, Rift Valley fever, Bartonellosis, or Lyme disease which are poorly understood due to lack of proper diagnostic testing. Currently, multimodal imaging has become a critical modality in the diagnosis and management of ocular diseases. Optical coherence tomography (OCT) is one such remarkable imaging modality in the field of ophthalmology providing high-resolution, cross-sectional images of the retina and choroid with the recent advances such as enhanced depth imaging and swept source OCT. Additionally, OCT angiography (...
Friday 9 June 2023
Tex Heart Inst J. 2022 Sep 1;49(5):e217777. doi: 10.14503/THIJ-21-7777.NO ABSTRACTPMID:36315845 | DOI:10.14503/THIJ-21-7777 (Source: Texas Heart Institute Journal)
Friday 9 June 2023
Eur Rev Med Pharmacol Sci. 2023 May;27(10):4378-4385. doi: 10.26355/eurrev_202305_32443.ABSTRACTLyme borreliosis is caused by the Gram-negative spirochetes Borrelia spp., particularly Borrelia burgdorferi sensu lato complex. The disease is transmitted through the bite of the infected black-legged Ixodes tick. Lyme borreliosis extensively occurs in the Northern Hemisphere, mainly in the United States. Lyme borreliosis cases are also detected in Asian countries including Korea, Nepal, China, Taiwan, and Japan. However, there is an inadequate understanding of Lyme borreliosis in the Southeast Asian region. Hence, this review aims to provide a brief update on the prevalence of Lyme borreliosis infection in Southeast Asia based on the latest literature on this issue. Lyme borreliosis has been d...
Friday 9 June 2023
During cutaneous tick attachment, the feeding cavity becomes a site of transmission for tick salivary compounds and tick-borne pathogens. However, the immunological consequences of tick feeding for human skin remain unclear. Here, we assessed human skin and blood samples upon tick bite and developed a human skin explant model mimicking Ixodes ricinus bites and tick-borne pathogen infection. Following tick attachment, we observed rapidly occurring patterns of immunomodulation, including increases in neutrophils and cutaneous B and T cells. T cells upregulated tissue residency markers, while lymphocytic cytokine production was impaired. In early stages of Borrelia burgdorferi model infections, we detected strain-specific immune responses and close spatial relationships between macrophages an...
Friday 9 June 2023
Dermatol Online J. 2023 Apr 15;29(2). doi: 10.5070/D329260769.ABSTRACTWithout prompt diagnosis and treatment, patients with Lyme disease may develop life threatening multi-organ system complications. As such, we discuss the key diagnostic features of the condition along with patient-specific suggested treatment protocols. Additionally, Lyme disease is reportedly expanding to regions that were previously not impacted, key epidemiological features are outlined. We discuss a patient with severe Lyme disease who presented with widespread cutaneous involvement and atypical pathologic findings within an uncharacteristic geographic region. Erythematous, annular patches and plaques with dusky-to-clear centers were initially observed on the right thigh and later extended to the trunk and bilateral ...
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Friday 9 June 2023
Curr Biol. 2023 May 22;33(10):R389-R394. doi: 10.1016/j.cub.2023.04.018.ABSTRACTIn the early 19th century, long before the discovery of the dinosaurs, scientists and the public alike were faced with the realization that strange beasts, wholly extinct, were once populating Earth's ancient oceans. In no small part, this realization was through the discovery of the first plesiosaurs (and ichthyosaurs) along the Dorset coast of England in the seaside town of Lyme Regis. There was this large marine reptile resembling a large sea turtle, but with four evenly shaped flippers and looking as though a large snake had been pulled through its carapace. It was soon to be named scientifically Plesiosaurus, in reference to its greater similarity to living reptiles than the Ichthyosaurus (Figure 1). While...
Friday 9 June 2023
Curr Biol. 2023 May 22;33(10):R389-R394. doi: 10.1016/j.cub.2023.04.018.ABSTRACTIn the early 19th century, long before the discovery of the dinosaurs, scientists and the public alike were faced with the realization that strange beasts, wholly extinct, were once populating Earth's ancient oceans. In no small part, this realization was through the discovery of the first plesiosaurs (and ichthyosaurs) along the Dorset coast of England in the seaside town of Lyme Regis. There was this large marine reptile resembling a large sea turtle, but with four evenly shaped flippers and looking as though a large snake had been pulled through its carapace. It was soon to be named scientifically Plesiosaurus, in reference to its greater similarity to living reptiles than the Ichthyosaurus (Figure 1). While...
Friday 9 June 2023
Dermatol Online J. 2023 Apr 15;29(2). doi: 10.5070/D329260769.ABSTRACTWithout prompt diagnosis and treatment, patients with Lyme disease may develop life threatening multi-organ system complications. As such, we discuss the key diagnostic features of the condition along with patient-specific suggested treatment protocols. Additionally, Lyme disease is reportedly expanding to regions that were previously not impacted, key epidemiological features are outlined. We discuss a patient with severe Lyme disease who presented with widespread cutaneous involvement and atypical pathologic findings within an uncharacteristic geographic region. Erythematous, annular patches and plaques with dusky-to-clear centers were initially observed on the right thigh and later extended to the trunk and bilateral ...
Friday 9 June 2023
Emerg Infect Dis. 2023 Jun;29(6):1091-1101. doi: 10.3201/eid2906.221685.ABSTRACTPatients who have Lyme neuroborreliosis (LNB) might experience lingering symptoms that persist despite antibiotic drug therapy. We tested whether those symptoms are caused by maladaptive immune responses by measuring 20 immune mediators in serum and cerebrospinal fluid (CSF) in 79 LNB patients followed for 1 year. At study entry, most mediators were highly concentrated in CSF, the site of the infection. Those responses resolved with antibiotic therapy, and associations between CSF cytokines and signs and symptoms of LNB were no longer observed. In contrast, subjective symptoms that persisted after use of antibiotics were associated with increased levels of serum interferon-α (IFN-α), which were already observ...
Friday 9 June 2023
PHM Session: Dermatologic Disease Presentations, Skin Color, and Disparities in Medical Care Presenters: Deawodi Ladzekpo, MD, and Sonya Tang Girdwood, MD, PhD, Cincinnati Children’s Hospital, Ohio Drs. Ladzekpo and Tang Girdwood brought to light disparities in medical care that result from the underrepresentation of dermatologic conditions in patients of color (POC). The topic was introduced with a reference to Lyme disease, in particular the fact that many POC aren’t diagnosed until they have advanced disease compared to white patients. The question was then put forth: Do POC not have symptoms until they are in the later stages? Or rather, does the lack of awareness of the appearance of erythema migrans on the skin of color delay their diagnosis and treatment? The first half of the s...
Friday 9 June 2023
In conclusion, our data indicate that Iripin-1 facilitates I. ricinus feeding by attenuating the host’s inflammatory response at the tick attachment site. (Source: Frontiers in Immunology)
Friday 9 June 2023
Ann Allergy Asthma Immunol. 2022 Dec 24:S1081-1206(22)02010-5. doi: 10.1016/j.anai.2022.12.025. Online ahead of print.ABSTRACTIn this paper, we discuss pertinent cutaneous findings that patients may present following travel to tropical destinations. We address arthropod-borne infectious diseases such as Cutaneous Leishmaniasis, Chagas Disease, Cutaneous Larvae Migrans, Myiasis, and others. We discuss other relevant diseases with cutaneous signs such as Monkey Pox and SARS-CoV-2. We provide clinicians with information regarding the background, diagnosis, treatment, and prevention of these tropical rashes. Additionally, we address the impact that climate change will have on the temporal and geographic incidence of these rashes. Viral, fungal, and vector-borne diseases have seen a geographic ...
Friday 9 June 2023
CONCLUSIONS: Language fluency appears to be an independent area of neurocognitive deficit within the constellation of PTLDS symptoms.PMID:36548120 | DOI:10.1093/arclin/acac095 (Source: Archives of Clinical Neuropsychology)
Friday 9 June 2023
Can J Neurol Sci. 2022 Dec 1:1-7. doi: 10.1017/cjn.2022.329. Online ahead of print.NO ABSTRACTPMID:36451597 | DOI:10.1017/cjn.2022.329 (Source: The Canadian Journal of Neurological Sciences)
Friday 9 June 2023
CONCLUSION: The strong immune response to the 41 kDa flagellin protein by the different mammalian species suggests the utility of a possible vaccine targeting this protein, although other proteins may also be appropriate, for preventing Lyme disease following a bite from an infected tick.PMID:36403566 | DOI:10.1016/j.biopha.2022.114013 (Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie)
Friday 9 June 2023
Michael Eriksen Benros, M.D., Ph.D. is professor and Head of Research at Mental Health Centre Copenhagen, Copenhagen University Hospital, Denmark. He received a two year grant from GLA for his study: Nationwide Cohort Studies Examining Psychiatric Disorders and Suicidal Behavior after Lyme disease. Abstract The immune system is linked to an increasing number of medical diseases, including lately also severe mental disorders. Utilizing the nationwide registers and biobanks in Denmark we have consistently displayed that infections and autoimmune diseases increases the risk of developing severe mental disorders in a dose-response relationship, where the risk of severe mental disorders particularly increases with the amount of infections exposed to. It is a broad range of infections and autoi...
Tuesday 6 June 2023
Eye on Innovation features exciting advances taking place at Mayo Clinic Laboratories. This monthly series shines a spotlight on recently developed tests and highlights how Mayo Clinic translates ideas and discoveries into testing resources that improve diagnosis and care for patients across the globe. ______________________________________________ It ’s long been known that Lyme disease is caused by bacteria transmitted through the bite of an infected black-legged tick (otherwise known as the deer tick). The understanding for many years was… (Source: News from Mayo Clinic)
Tuesday 6 June 2023
Lyme Disease May Up Risk for Mental Illness, Suicidal Behavior (Source: eMedicineHealth.com)
Tuesday 6 June 2023
FINDINGSA UCLA study suggests that many physicians may not have the knowledge or training to properly recognize how Lyme disease appears on the skin of Black patients. The disease, caused by the tick-borne Borrelia bacterium, generally begins with a bull ’s-eye–shaped rash on the skin, along with fever, headache, chills and muscle pain; if not diagnosed promptly and treated with antibiotics, it can lead to more severe and long-lasting symptoms.UCLA ’s Dr. Dan Ly found that approximately 1 in 3 Black patients who were newly diagnosed with Lyme disease already had related neurological complications such as meningitis, neuropathy and cranial neuritis — an indication that the disease may not have been properly diagnosed in its earlier stages. Less than 1 in 10 newly diagnosed white pat...
Tuesday 6 June 2023
Researchers found that a neglected antibiotic called hygromycin A selectively kills the bacteria that cause Lyme disease. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Tuesday 6 June 2023
For the first time, Lyme disease-carrying ticks -- typically associated with woodlands in New England and other forested regions of the US -- have been found in abundance near beaches in Northern California, new research shows.WebMD Health News (Source: Medscape Infectious Diseases Headlines)
Tuesday 6 June 2023
Lyme disease-carrying ticks usually found in woodlands and fields are spreading along California's beaches, carried by an unknown host. (Source: Los Angeles Times - Science)
Tuesday 6 June 2023
Scientists are studying why tick-borne infections, including Lyme disease, are on the rise and why ticks are expanding into new geographic areas. Lyme disease, the most common tick-borne infection, is caused by the bacteria Borrelia burgdorferi and Borrelia mayonii. It's transmitted by the bite of an infected blacklegged tick, previously known as a deer tick. The Northeast and Upper Midwest are hot spots for Lyme disease, though there are other parts of the U.S. and the world… (Source: News from Mayo Clinic)
Tuesday 6 June 2023
WEDNESDAY, July 31, 2019 -- The incidence of Lyme disease (LD) increased from 2001 to 2012 in the United Kingdom, with an estimated incidence rate of 12.1 per 100,000 individuals per year, according to a study published online July 30 in BMJ... (Source: Drugs.com - Pharma News)
Tuesday 6 June 2023
The trends show that tick-borne illnesses are becoming a more common concern nationally, not just in the areas where Lyme disease has been found historically.WebMD Health News (Source: Medscape Infectious Diseases Headlines)
Tuesday 6 June 2023
Cases of a nasty infection passed on through tick bites may be much higher in the UK than previously thought, according to new research. (Source: Nursing Times)
Tuesday 6 June 2023
Insurance Data Shows Big Rise in Lyme Disease in US (Source: eMedicineHealth.com)
Tuesday 6 June 2023
Several groups have differing guidelines for diagnosing and treating Lyme. Too much is in dispute, since our knowledge is so limited. (Source: Forbes.com Healthcare News)
Tuesday 6 June 2023
(Virginia Tech) The awards are designed to support established and up-and-coming scientists who have identified new and defined approaches to improve diagnostics or therapeutics for Lyme disease. (Source: EurekAlert! - Medicine and Health)
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Tuesday 6 June 2023
At my animal hospital in upstate New York, an epicenter of the U.S. tick epidemic, my dog Fawn lets out a whimper as the veterinarian injects her with her annual Lyme disease shot. I roll my eyes. She doesn’t know how good she has it. The injection means that if a tick bites her (and in rural New York, a tick always does), the creepy crawly will feast on dog blood that’s been supercharged with a Lyme bacteria-killing substance, and Lyme disease won’t be transmitted to Fawn. I wish I could be shot up with that superpower. Currently, there is no human vaccine for Lyme disease—even though more than two decades ago, people could get a safe and effective preventative shot similar to Fawn’s. Now, thanks to potent anti-vaccine pushback, all we can do is try to avoid ...
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Tuesday 6 June 2023
Research has found strains of Klebsiella pneumoniae resistant to the carbapenems spreading through hospitals Related items fromOnMedica GPs given help to spot Lyme disease Single-dose malaria drug eliminates parasite from liver Antibiotic research programme launched Measles cases triple in Europe but immunisation rates grow Chief medical officer launches push for flu jab drive (Source: OnMedica Latest News)
Tuesday 6 June 2023
The former “Bachelorette” winner has Lyme disease that was triggered by high levels of mold in his body, he shared on wife Trista... (Source: Reuters: Health)
Tuesday 6 June 2023
An economic evaluation of the costs associated with Lyme disease underscores the importance of effective prevention measures.Emerging Infectious Diseases (Source: Medscape Today Headlines)
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Tuesday 6 June 2023
MONDAY, June 5, 2023 (American Heart Association News) -- Warmer weather is drawing people outdoors to enjoy nature. But for those who spend time working in the garden or walking along wooded or grassy trails, it also means greater exposure to a... (Source: Drugs.com - Daily MedNews)
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Tuesday 6 June 2023
MONDAY, June 5, 2023 -- Ticks are extremely resilient even when temperatures vary wildly, according to scientists who are working to better understand the spread of Lyme disease. In their new study, black-legged ticks, notorious for carrying... (Source: Drugs.com - Daily MedNews)
Tuesday 6 June 2023
A Yale-developed vaccine that helps more quickly identify tick bites on guinea pigs could offer humans protection against Lyme Disease and other pathogens. (Source: Yale Science and Health News)
Tuesday 6 June 2023
US pharma group to pay €90.5mn for 8% in deal that will boost joint Lyme disease programme (Source: FT.com - Drugs and Healthcare)
Tuesday 6 June 2023
The Infectious Diseases Society of America (IDSA) could have chosen to settle the lawsuit instead of fighting it, but the principles at stake were too high, they decided.Medscape Medical News (Source: Medscape Rheumatology Headlines)
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Tuesday 6 June 2023
(The Translational Genomics Research Institute) The findings of a recent analysis conducted by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest that ecosystems suitable for harboring ticks that carry debilitating Lyme disease could be more widespread than previously thought in California, Oregon and Washington. Bolstering the research were the efforts of an army of " citizen scientists " who collected and submitted 18,881 ticks over nearly three years. (Source: EurekAlert! - Infectious and Emerging Diseases)
Tuesday 6 June 2023
DR ELLIE CANNON: There are between 2,000 and 3,000 cases of Lyme disease every year in England and Wales - with areas such as the New Forest and Scottish Highlands the highest risk. (Source: the Mail online | Health)
Tuesday 6 June 2023
DEAR MAYO CLINIC: A close friend was diagnosed recently with Lyme disease due to a tick bite. However, I recently read about some new type of tick-borne illness. My family loves to hike and be outdoors, but I'm nervous now about continuing our activities. How can I reduce our risk of illness from insect bites and protect my family? ANSWER: Enjoying the outdoors is a wonderful way to spend quality family time together, but there are certainly… (Source: News from Mayo Clinic)
Tuesday 6 June 2023
TUESDAY, Aug. 17, 2021 -- Patients hospitalized with Lyme disease have a higher rate of mental disorders and attempted suicide after infection, according to a study published online July 28 in The American Journal of Psychiatry. Brian A. Fallon,... (Source: Drugs.com - Pharma News)
Tuesday 6 June 2023
Child abuse is one of the most common causes for child fatality in the United States. Inaccurate reporting of child abuse combined with scarcity of resources for child abuse evaluations can lead to unintended consequences for children and their families. T... (Source: SafetyLit)
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Tuesday 6 June 2023
SUNDAY, July 25, 2021 -- When you're heading outdoors this summer, keep an eye out for ticks during and after your outing, health experts say. These common parasites can transmit Lyme disease, a potentially serious illness. Lyme disease is... (Source: Drugs.com - Daily MedNews)
Tuesday 6 June 2023
Scientists in southern China estimated as many as 32million Americans may have had the disease at some point in their lives. Globally, up to 14 percent of people are thought to have been infected. (Source: the Mail online | Health)
Tuesday 6 June 2023
App Helps Screen for Autism Spectrum Disorder Step It Up! : Get Active for Your Health Disruptive Leg Movement? : Managing Restless Legs Syndrome Protect Yourself From Lyme Disease Noisy Planet (Source: NIH News in Health)
Tuesday 6 June 2023
Title: What Is Lyme Disease in Humans?Category: Diseases and ConditionsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 2/12/2021 12:00:00 AM (Source: MedicineNet Arthritis General)
Tuesday 6 June 2023
Recent guidance from several specialty societies can answers many patients'questions and aid clinical decision-making regarding tick bites.Medscape Family Medicine (Source: Medscape Infectious Diseases Headlines)
Tuesday 6 June 2023
Lyme prevalence is increasing. Are we paying attention?Medscape (Source: Medscape Today Headlines)
Tuesday 6 June 2023
The disease is most often caused by the tiny parasites and transmitted to humans in warmer months by deer ticks — the same ones that spread Lyme disease. (Source: Washington Post: To Your Health)
Tuesday 6 June 2023
(Cary Institute of Ecosystem Studies) A new study published in the journalGlobal Ecology and Biogeography used machine learning to identify bird species with the potential to transmit the Lyme disease bacterium (Borrelia burgdorferi) to feeding ticks. The team developed a model that identified birds known to spread Lyme disease with 80% accuracy and flagged 21 new species that should be prioritized for surveillance. (Source: EurekAlert! - Medicine and Health)
Tuesday 6 June 2023
LYME DISEASE is an infection spread by ticks and is potentially life-threatening. How common is lyme disease in the UK? (Source: Daily Express - Health)
Tuesday 6 June 2023
Lyme disease was first named nearly 50 years ago in Lyme, Connecticut, but the tick-borne disease is now found around the world. A new study published in BMJ Global Health estimates that 14.5% of the world’s population has, at some point, been infected with Lyme disease, which can cause short-term symptoms including a skin rash, fever, headache, and fatigue—as well as long-term ones, including damage to the joints, heart, and nervous system. The scourge also appears to be getting worse. Lyme prevalence has doubled from 2010 to 2021, compared to 2001 to 2010. [time-brightcove not-tgx=”true”] The study, led by a team of researchers from the Institute for Tropical Medicine at Kunming Medical University in China, was a meta-analysis of 89 studies dating as far back as ...
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Tuesday 6 June 2023
"I don’t think we were expecting to find many ticks, but we did, and we found heaps of ticks in big numbers. And they’re infected with diseases," the study's lead author said. (Source: Washington Post: To Your Health)
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Tuesday 6 June 2023
Roughly 500,000 people across the United States are diagnosed with Lyme disease each year, according to new estimates released Wednesday by the CDC, but researchers raise concern that some people may be misdiagnosed. (Source: Health News - UPI.com)
Tuesday 6 June 2023
Steven Williams, 36, said his fit, active life was "totally devastated" by the struggle for answers. (Source: BBC News | Health | UK Edition)
Tuesday 6 June 2023
TUESDAY, June 14, 2022 -- The reported estimated global seroprevalence of Borrelia burgdorferi sensu lato (Bb) is 14.5 percent, according to a systematic review and meta-analysis published online June 13 in BMJ Global Health. Yan Dong, from the... (Source: Drugs.com - Pharma News)
Tuesday 6 June 2023
NIH researcher Andaleeb Sajid discusses her study ’s finding that ticks were unable to feed on vaccinated guinea pigs, preventing transmission of the pathogen that causes Lyme disease. (Source: The Scientist)
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Tuesday 6 June 2023
The meeting will bring together researchers and scientists from across the SUNY system. (Source: SUNY Upstate Medical)
Tuesday 6 June 2023
Did spending more time indoors during the COVID-19 pandemic result in fewer reported cases of Lyme disease?Emerging Infectious Diseases (Source: Medscape Today Headlines)
Tuesday 6 June 2023
Lyme disease has infected more than 14% of the world's population, according to a new study. "It's significant," says Dr. Bobbi Pritt, director of the Clinical Parasitology Laboratory at Mayo Clinic. "If you look at the numbers and how it breaks down in regions across the United States, in some areas, that exceeds 50% seropositivity. That means people are walking around with antibodies in their blood that are detectable. That shows they've been exposed to Lyme disease at some… (Source: News from Mayo Clinic)
Tuesday 6 June 2023
WebMD sat down with New York Times columnist Ross Douthat to find out a little bit more about his journey and what he recommends to anyone with Lyme Disease. (Source: WebMD Health)
Tuesday 6 June 2023
FRIDAY, Dec. 11, 2020 -- In new evidence-based clinical practice guidelines, published online Nov. 30 in Clinical Infectious Diseases, recommendations are presented for the prevention, diagnosis, and treatment of Lyme disease. The guidelines were... (Source: Drugs.com - Pharma News)
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Tuesday 6 June 2023
An exciting new finding by. Dr. Kim Lewis of Northeastern University gives hope that Lyme disease can be potentially treated without harming the microbiome.(PRWeb October 07, 2021)Read the full story at https://www.prweb.com/releases/global_lyme_alliance_congratulates_dr_kim_lewis_on_groundbreaking_publication_a_selective_antibiotic_for_lyme_disease/prweb18247374.htm (Source: PRWeb: Medical Pharmaceuticals)
Tuesday 6 June 2023
Researchers from China, who examined blood sample data from studies involving more than 150,000 people, found 14.5 per cent had Lyme disease. (Source: the Mail online | Health)
Tuesday 6 June 2023
When health experts talk about the remarkable efficacy of COVID-19 vaccines, they typically point to their ability to prevent severe disease and death. Fully vaccinated people can still get “breakthrough” infections from the virus that causes COVID-19—but compared to an unvaccinated person, they’re more than 10 times less likely to be hospitalized or die from their illness, according to U.S. Centers for Disease Control and Prevention (CDC) research. Officials often point to these impressive figures as evidence that we can tame COVID-19 into a mostly mild illness that behaves like a routine cold or flu, and thus with which we can coexist. After all, the vaccines were not designed to quash viral spread entirely; they were designed to defang the virus by preventing its...
Tuesday 6 June 2023
New clinical practice guidelines on Lyme disease place a strong emphasis on antibody testing to assess for rheumatologic and neurologic syndromes.Medscape Medical News (Source: Medscape Infectious Diseases Headlines)
Tuesday 6 June 2023
Increased inflammation, immune activation, and psychological factors may help explain the association of Lyme disease with higher rates of psychiatric disorders and suicidal behavior, researchers say.Medscape Medical News (Source: Medscape Medical News Headlines)
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Tuesday 6 June 2023
Last year, Diana Berrent—the founder of Survivor Corps, a Long COVID support group—asked the group’s members if they’d ever had thoughts of suicide since developing Long COVID. About 18% of people who responded said they had, a number much higher than the 4% of the general U.S. adult population that has experienced recent suicidal thoughts. A few weeks ago, Berrent posed the same question to current members of her group. This time, of the nearly 200 people who responded, 45% said they’d contemplated suicide. While her poll was small and informal, the results point to a serious problem. “People are suffering in a way that I don’t think the general public understands,” Berrent says. “Not only are people mourning the life that they thought...
Tuesday 6 June 2023
(Source: The Doctors Lounge - Psychiatry)
Tuesday 6 June 2023
(Yale University) Yale researchers have discovered a protein that helps protect hosts from infection with the tick-borne spirochete that causes Lyme Disease, a finding that may help diagnose and treat this infection, they report Nov. 11 in the journalPLOS Pathogens. (Source: EurekAlert! - Medicine and Health)
Tuesday 6 June 2023
The clinical manifestations of this tickborne disease can differ according to the species causing the infection.Emerging Infectious Diseases (Source: Medscape Today Headlines)
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Tuesday 6 June 2023
TUESDAY, June 7, 2022 -- American farmers are at increased risk for tick bites, but new research shows they are doing little to defend themselves against the insects and the illnesses they cause. Tick-borne diseases include Lyme disease, Rocky... (Source: Drugs.com - Daily MedNews)
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Tuesday 6 June 2023
OBJECTIVE: Lyme borreliosis is a tick-borne infectious disease that may confer an increased risk of mental disorders, but previous studies have been hampered by methodological limitations, including small sample sizes. The authors used a nationwide retrosp... (Source: SafetyLit)
Tuesday 6 June 2023
DiscussionMusculoskeletal problems are common problems in pediatric practice with up to 15% of acute care visits being for this problem. Joint pain is a common concern for families but the differential diagnosis is extensive and needs thoughtful consideration. History is a key to discerning the potential diagnosis but also in guiding the physical examination and laboratory examination. Family history especially for systemic diseases should be considered. On physical examination all joints should be examined include sacroiliac and temporomandibular joints. Is this arthritis or arthralgia? Distinction between inflammatory and non-inflammatory joints is important. Joints with inflammation are painful or stiff after rest and improve with activity. Joints without inflammation are better afte...
Tuesday 6 June 2023
One element of Upstate's work on Lyme disease and ticks is it's wildly successful tick identification program. Since April, more than 13,000 ticks have been sent to Upstate, with nearly one-third carrying some sort of infectious disease. (Source: SUNY Upstate Medical)
Tuesday 6 June 2023
Russell Bell, 65, from Raleigh in North Carolina, was only diagnosed with the tick-borne disease after he went for tests nine months after developing symptoms. He died earlier this year. (Source: the Mail online | Health)
Tuesday 6 June 2023
This updated toolkit provides background information on ticks, Lyme disease risk, how to improve awareness of ticks and mitigate against tick-borne diseases through the promotion of Public Health England's key message which is to'be tick aware'. (Source: Current Awareness Service for Health (CASH))
Tuesday 6 June 2023
A few years ago, Jaime Seltzer was helping coordinate research projects, grant applications and funding for a Stanford research group studying a condition called myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Up to 2.5 million Americans, including Seltzer, have ME/CFS, and yet it felt like almost no one paid attention to her group’s research. “What is it going to take for researchers to take ME seriously?” she and her colleagues often wondered aloud. The morbid answer, they hypothesized, was a pandemic. Since ME/CFS often follows viral infections, they feared it would take something as destructive as mass illness for the larger scientific community to take notice. Unfortunately, this year they were proven right. As the COVID-19 pandemic presses on, doctors ...
Tuesday 6 June 2023
La enfermedad de Lyme est á proliferando. ¿Cómo puede prevenirla? ¿Cuáles son los síntomas y qué debe hacer si cree haberla contraído? (Source: FDA Center for Drug Evaluation and Research - What's New)
Tuesday 6 June 2023
Russell Bell, 65, from Raleigh in North Carolina, was only diagnosed with the tick-borne disease after he went for tests nine months after developing symptoms. He died earlier this year. (Source: the Mail online | Health)
Tuesday 6 June 2023
Dr Paul Auwaerter highlights the major changes in this guideline, which was a collaboration of the IDSA, AAN, and ACR.Medscape Infectious Diseases (Source: Medscape Infectious Diseases Headlines)
Tuesday 6 June 2023
(Virginia Tech) Renowned tick immunobiologist Utpal Pal wants to adapt the rabies vaccination platform to produce antibodies that can protect against Borrelia burgdorferi, the bacteria responsible for Lyme disease. The intention is to apply this work to other tick-borne diseases in the future. (Source: EurekAlert! - Medicine and Health)
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Tuesday 6 June 2023
The blood-sucking critters are capable of thriving along the western coast, according to new research. Though experts don't exactly know how they're picking up the bacteria that causes the illness.(Image credit: James Gathany/AP) (Source: NPR Health and Science)
Tuesday 6 June 2023
A nine-year-old pointed out what was missing in Lyme Regis. Her long campaign has now borne fruitIt all began with a curious nine-year-old and a question that she asked her mother. Where in their hometown of Lyme Regis was the statue ofMary Anning, the pioneering Victorian fossil hunter who, she had recently discovered, had lived and worked there?There wasn ’t one, Anya Pearson was forced to tell her indignant daughter. Anning’s lifetime of discoveries – including finding the first ichthyosaur skeleton at the age of just 12 – may have profoundly shaped the emerging science of palaeontology, but in her own Dorset town and farther afield, she had been largely forgotten.Continue reading... (Source: Guardian Unlimited Science)
Tuesday 6 June 2023
From what to do when a patient presents with a tick, to which antibiotic to select for treatment.Medscape Family Medicine (Source: Medscape FamilyMedicine Headlines)
Tuesday 6 June 2023
(Rutgers University) A tick species associated with bats has been reported for the first time in New Jersey and could pose health risks to people, pets and livestock, according to a Rutgers-led study in the Journal of Medical Entomology. This species (Carios kelleyi) is a " soft " tick. Deer ticks, which carry Lyme disease, are an example of " hard " ticks. (Source: EurekAlert! - Infectious and Emerging Diseases)
Tuesday 6 June 2023
Don Murry Grubbs, from White House, Tennessee was diagnosed with two tick-borne illnesses - Lyme disease and Rocky Mountain Spotted Fever - after being bitten by two different ticks. (Source: the Mail online | Health)
Tuesday 6 June 2023
Americans can avoid contracting Lyme disease, if they take a few simple steps. The steps include regular tick checks, wearing long sleeves in areas of high exposure and using bug spray. (Source: the Mail online | Health)
Tuesday 6 June 2023
(University of Maryland) The University of Maryland (UMD) received funding from the Steven& Alexandra Cohen Foundation to develop novel therapeutic strategies to stop infection from Lyme disease pathogens before it begins. Unlike traditional antibiotics that attack the pathogen directly and put it on the defensive, UMD is exploring antimicrobials that would interfere with the pathogen on a biomolecular level to inhibit it from causing an infection in the first place. (Source: EurekAlert! - Infectious and Emerging Diseases)
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Tuesday 6 June 2023
It ’s not just Covid-19. Pathogens once confined to nature are making their way into humans on a more regular basis. And it’s our fault. (Source: NYT Health)
Tuesday 6 June 2023
This winter was one of the warmest on record, and lingering summer heat could add weeks of outdoor activity to animals that carry ticks, which thrive in hot, humid conditions. (Source: WebMD Health)
Tuesday 6 June 2023
LYME disease is a type of bacterial infection spread to humans from infected ticks. While not much of a problem during the winter, Lyme disease can be a danger during the summer. As a result, it's important to be wary of the symptoms to look out for. (Source: Daily Express - Health)
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Tuesday 6 June 2023
In Northern California, the proportion of ticks infected with the bacterium Borrelia burgdorferi was the same in shrubland along beaches as in woodland habitats. (Source: The Scientist)
Tuesday 6 June 2023
Lyme and Covid-19 are replacing syphilis as the great masquerader. They share many puzzling symptoms and are all easily missed. (Source: Forbes.com Healthcare News)
Tuesday 6 June 2023
Promising data show that a viral gene in the Lyme disease-causing bacteria can distinguish between early and late infection.Medscape Medical News (Source: Medscape Rheumatology Headlines)
Tuesday 6 June 2023
The lone star tick can trigger an allergic reaction to red meat in those bitten. Now this arachnid ’s territory is expanding. (Source: NYT Health)
Tuesday 6 June 2023
US drugmaker and French partner begin late-stage trial with 14% of global population showing evidence of infection (Source: FT.com - Drugs and Healthcare)
Tuesday 6 June 2023
The E.P.A. has approved nootkatone, which is found in cedars and grapefruit. It repels ticks, mosquitoes and other dangerous bugs for hours, but is safe enough to eat. (Source: NYT Health)
Tuesday 6 June 2023
LYME disease is a bacterial infection that is passed on to humans by infected ticks. High-risk areas include grassy and wooded areas, making that leisurely stroll not seem so idyllic any more. Look for a sign on your knee that you may be needing a visit to your doctors pronto. (Source: Daily Express - Health)
Tuesday 6 June 2023
Patients with localized disease had the lowest attributed costs, highlighting the importance of early diagnosis and intervention.Medscape Medical News (Source: Medscape Medical News Headlines)
Tuesday 6 June 2023
LYME disease is a bacterial infection which could lead to severe physical and mental problems if not diagnosed at an early stage. Spotting the early warning signs will ensure prompt treatment and noticing this peculiar feeling in the head could mean you're at risk. (Source: Daily Express - Health)
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Tuesday 6 June 2023
Insects can pass along serious illnesses, such as Lyme disease and West Nile virus. Because of covid-19, health agencies are focusing less on these problems. (Source: Washington Post: To Your Health)
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Tuesday 6 June 2023
ORONO, Maine (AP) — More than a third of the deer ticks submitted to a Maine lab last year tested positive for Lyme disease, a surveillance report from the lab said. The report is from the University of Maine Tick Lab. The lab found that a smaller percentage of ticks tested positive for anaplasmosis and babesiosis, which are other tick-borne diseases. The tick lab’s manager, Griffin Dill, said the information will help authorities learn how fast the ticks are spreading in the state. The study is the first of its kind in Maine, the Bangor Daily news reported. The report found that just shy of 39% of deer ticks tested positive for Lyme. The data also show ticks were more frequently found higher on the bodies of children than adults. Lyme disease can cause symptoms such as neck stiffn...
Tuesday 6 June 2023
GPs are failing to spot the early signs of Lyme disease, an infection spread through tick bites that is on the rise in the UK, experts warn. Early diagnosis allows treatment with anti-biotics. (Source: the Mail online | Health)
Tuesday 6 June 2023
Engineers with the University of Cincinnati have created a tiny portable lab that plugs into your phone, connecting it automatically to a doctor's office through a custom app UC developed. The lab the size of a credit card can diagnose infectious diseases such as coronavirus, malaria, HIV or Lyme disease or countless other health conditions like depression and anxiety. (Source: World Pharma News)
Tuesday 6 June 2023
LYME disease is a debilitating bacterial infection and with lockdowns easing and more people venturing outside, knowing the potential risks and symptoms is extremely important. If you experience any of these six, lesser-known warning signs you may be at risk. (Source: Daily Express - Health)
Tuesday 6 June 2023
AUGUSTA, Maine (AP) — Maine reported a record number of Lyme disease cases last year, and the number could rise as data continues to trickle in, officials said Thursday. There were at least 2,079 cases in 2019, the Maine Center for Disease Control and Prevention reported. It’s too early to say why the numbers grew last year. But the numbers underscore the importance of taking precautions to avoid tick bites, said Dr. Nirav Shah, director of the Maine CDC. Winter is a time of low ticket activity. But ticks can be active when the temperature climbs above 40, as it did last weekend in Maine. The state also experienced increases in two other tickborne diseases, with 685 cases of anaplasmosis and 138 cases of babesiosis. Lyme disease is caused by bacteria carried by infected deer ticks....
Tuesday 6 June 2023
When Virginia Sen. Tim Kaine came down with a “blizzard” of allergy-like symptoms in March 2020, he blamed the layer of pollen coating his car. “It was Washington, D.C., in late March,” he says. I thought, “‘Okay, well, this is hay fever gone wild.’” Only when his wife, Anne Holton, developed “textbook” COVID-19 symptoms did Kaine start to wonder if he might have the new virus, the subject of the massive economic assistance bill—the CARES Act—that he and other lawmakers were then working to pass. Testing at that time was hard to come by, even for Hillary Clinton’s 2016 running mate, but antibody tests later revealed that Kaine and Holton had been infected by the virus that causes COVID-19. [time-brightcove not-t...
Tuesday 6 June 2023
A engineer forced to quit work hopes pop star Justin Bieber will raise awareness of the condition. (Source: BBC News | Health | UK Edition)
Tuesday 6 June 2023
New Hampshire has signed into law a bill that establishes a commission to study the limitations of current testing for Lyme disease and other tick-borne illnesses and available treatment.Associated Press (Source: Medscape Infectious Diseases Headlines)
Tuesday 6 June 2023
Here is why Lyme Disease is tough to diagnose, tough to understand, and tough to have. (Source: Forbes.com Healthcare News)
Tuesday 6 June 2023
Discussion Vocal cord function involves balancing muscular and neuronal functions. The superior laryngeal nerves (SLN) and recurrent laryngeal nerves (RLN) are the main nerves responsible for sensation and motor innervation. There are two sides to the larynx and they operate ipsilaterally, therefore one side can be affected while the other is not. Vocal cord paresis or paralysis are “an impairment of the vocal fold motor function that is caused by nerve or neuromuscular abnormalit[ies].” Paresis involves some maintenance of vocal cord movement while paralysis does not. Paresis is also more of a continuum than an absolute movement or not. “Paresis is often considered idiopathic, but potentially any pathology present from skull base to mediastinum that compresses, tethers, ...
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Tuesday 6 June 2023
More details about his affliction will be unveiled in an upcoming documentary series, Bieber said. (Source: Washington Post: To Your Health)
Tuesday 6 June 2023
LYME disease is a bacterial infection which is transmitted by a tick bite. Feeling this sensation in your head could mean you're at risk. (Source: Daily Express - Health)
Tuesday 6 June 2023
Here are some of the latest health and medical news developments, compiled by the editors of HealthDay: Justin Bieber Reveals He Has Lyme Disease Singer Justin Bieber says he has Lyme disease. He revealed his condition Wednesday in an Instagram... (Source: Drugs.com - Daily MedNews)
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Tuesday 6 June 2023
Common measures to kill the harmful pests appear to protect pets more than people, researchers say. (Source: WebMD Health)
Tuesday 6 June 2023
In Lyme disease-endemic areas, a C6 peptide enzyme immunoassay (EIA) test may help guide initial management of children with acute arthritis, an observational study suggests.Reuters Health Information (Source: Medscape Orthopaedics Headlines)
Tuesday 6 June 2023
Pasos para ayudar a prevenir las picaduras y las enfermedades. ... por: Sarah Elizabeth Adler, AARP, 14 de julio de 2020 | ... In English | Garrapatas: Son las peque ñas plagas que interrumpen la di... (Source: AARP.org News)
Tuesday 6 June 2023
Tuesday 6 June 2023
Title: What Is Chronic Lyme Disease (Stage 3)?Category: Diseases and ConditionsCreated: 6/17/2020 12:00:00 AMLast Editorial Review: 4/8/2022 12:00:00 AM (Source: MedicineNet Arthritis General)
Tuesday 6 June 2023
Insurance claim lines related to Lyme disease, a bacterial infection transmitted through the bite of black-legged ticks, increased by 117 percent across the country between 2007 and 2018, according to new research. (Source: Health News - UPI.com)
Tuesday 6 June 2023
Her lethargy and joint pain suggested a tick-borne illness. Adding to the mystery, was a recent trip abroad a clue or a red herring? (Source: NYT Health)
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Tuesday 6 June 2023
(FAIR Health) From 2007 to 2018, claim lines with diagnoses of Lyme disease increased nationally 117%. The new FAIR Health Study Uncovers Geographic, Age and Gender Variation, among Other Notable Statistics. Comparing Lyme disease to other tick-borne diseases, the study draws on data from FAIR Health's comprehensive repository of over 29 billion private healthcare claim records -- the largest in the country. (Source: EurekAlert! - Infectious and Emerging Diseases)
Tuesday 6 June 2023
A test that detects antiphospholipid antibodies in the blood of Lyme disease patients shows potential for identifying the disease sooner than current methods and possibly tracking response to therapy and recurrence, researchers say.Reuters Health Information (Source: Medscape Pathology Headlines)
Tuesday 6 June 2023
Scientists at Columbia University, New York, are developing test that uses microchips to detect antibodies against Lyme disease. The condition, spread by ticks, can be fatal to humans. (Source: the Mail online | Health)
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Tuesday 6 June 2023
(Harvard Medical School) A $5 million donation to Harvard Medical School will propel Lyme disease research, education (Source: EurekAlert! - Medicine and Health)
Tuesday 6 June 2023
Fundamental misunderstandings exist among both patients and practitioners about the nature of tick-borne infections. This review aims to address these issues from the neurologist's perspective.Seminars in Neurology (Source: Medscape Today Headlines)
Tuesday 6 June 2023
ALEC BALDWIN, 64, said his family "live in fear" of Lyme disease after the star was "attacked" by the condition for two decades. (Source: Daily Express - Health)
Tuesday 6 June 2023
Fewer than 40% of those bitten by a tick transmitting Lyme disease will have a bullseye rash, and ticks are incredibly small (about the size of a sesame seed), so are easily missed. (Source: Forbes.com Healthcare News)
Tuesday 6 June 2023
LYME disease is a bacterial infection that can be spread to humans by infected ticks, tiny spider-like creatures that dwell in woodland. Untreated Lyme disease can cause a host of debilitating health problems so it is vital to act on the early warning sign. (Source: Daily Express - Health)
Tuesday 6 June 2023
LYME disease is an infectious disease caused by a bacterium named Borrelia, spread by ticks found in the woods. It can easily be caught and if a person experiences this one particular sign it could be a major warning that you may be at risk of having the disease. What is it? (Source: Daily Express - Health)
Tuesday 6 June 2023
ACTOR Ben Stiller, who starred in classics like Night at the Museum and Meet the Fockers was diagnosed with Lyme disease. The star underwent lots of tests before he finally discovered the reality of his situation. (Source: Daily Express - Health)
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Tuesday 6 June 2023
As vectors for Lyme disease, black-legged ticks present a public health crisis in North America. Are current prevention recommendations appropriate? Where should prevention efforts be focused?American Journal of Epidemiology (Source: Medscape Today Headlines)
Tuesday 6 June 2023
The coronavirus testing debacle, much like early Lyme testing, is a reminder that diagnostics aren't perfect.Undark (Source: Medscape Medical News Headlines)
Tuesday 6 June 2023
Waiting for test results before initiating therapy for patients suspected of having Lyme carditis may result in death, data from two recent cases show.Medscape Medical News (Source: Medscape Internal Medicine Headlines)
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Tuesday 6 June 2023
The number of ticks sent to the Upstate lab as part of its citizen science program has skyrocketed with more than 30 percent found to be carrying Lyme disease. (Source: SUNY Upstate Medical)
Tuesday 6 June 2023
Rapid assay for Lyme disease could lead to a practical test for use by healthcare providers. (Source: National Institutes of Health (NIH) News Releases)
Tuesday 6 June 2023
Title: What Are the Symptoms of Lyme Disease by Stages?Category: Diseases and ConditionsCreated: 6/17/2020 12:00:00 AMLast Editorial Review: 6/17/2020 12:00:00 AM (Source: MedicineNet Arthritis General)
Tuesday 6 June 2023
Discussion Lyme disease (LD) is caused by several genospecies of Borrelia burgdorferi senu lato that are transmitted by ticks of the Ixodes ricinus complex. In the U.S. and Europe it is the most common vector-borne disease. It is named for Lyme, Connecticut in the 1970s when it was “discovered,” but there are reports of LD-type disease in Europe since 1883. There are 18 distinct genospecies with B. afzelii, B. garinii and B. burgdorferi sensu stricto being the 3 most common ones causing human infection. There are many species of Ixodes ticks but only 4 commonly bite humans. Ixodes ricinus mainly in Europe, I, persultcatus in Asia, I. scapularis in the eastern and central US, and I. pacificus in the western US and Canada. However I. pacificus is rarely infected and accounts for ...
Tuesday 6 June 2023
The number of ticks sent to the Upstate lab as part of its citizen science program has skyrocketed with more than 30 percent found to be carrying Lyme disease. (Source: SUNY Upstate Medical)
Tuesday 6 June 2023
Most people who think they have chronic Lyme disease are more likely to have chronic fatigue syndrome, say experts. (Source: BBC News | Health | UK Edition)
Tuesday 6 June 2023
(Cornell University) New Cornell-led research shows that inadequate funding is the main barrier to better surveillance and control of ticks, including the blacklegged tick, which spreads Lyme disease, the No. 1 vector-borne illness in the country. (Source: EurekAlert! - Biology)
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Tuesday 6 June 2023
The first human Lyme vaccine was pulled off the market nearly 20 years ago. A new effort faces lingering suspicions.Undark (Source: Medscape Allergy Headlines)
Tuesday 6 June 2023
Two years into the COVID-19 pandemic, questions about Long COVID still outnumber answers. Why do some people develop long-lasting symptoms—often after a mild case of COVID-19, sometimes even after being vaccinated—while others fully recover from their brushes with the SARS-CoV-2 virus? Why does Long COVID seem to disproportionately appear in women? How can one condition affect numerous bodily systems, causing symptoms ranging from brain fog to joint pain to total exhaustion? Is Long COVID a single diagnosis, or is it better understood as an umbrella term for a spectrum of disease, caused by a range of biologically diverse effects of the virus? Or, could it actually be a new manifestation of post-viral illnesses that have been around for decades? [time-brightcove not-tgx=”...
Tuesday 6 June 2023
Dr Paul Auwaerter comments on the newly approved, modified two-tier approach for diagnosing Lyme disease.Medscape Infectious Diseases (Source: Medscape Infectious Diseases Headlines)
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Tuesday 6 June 2023
With America on lockdown the past two months, many people turned to the woods for safe isolation and social distancing. And now as sections of the country reopen and summer approaches, the outdoors...(PRWeb June 02, 2020)Read the full story at https://www.prweb.com/releases/knowing_signs_and_symptoms_of_lyme_disease_is_critical_for_early_detection_and_treatment_says_industry_leading_quidel/prweb17162063.htm (Source: PRWeb: Medical Pharmaceuticals)
Tuesday 6 June 2023
Analysis (n=2361) noted significant increase (p (Source: Current Awareness Service for Health (CASH))
Tuesday 6 June 2023
Ticks have evaded gene editing attempts for years, but scientists have finally figured out how to effectively modify their genome as they work to reduce disease transmission.WebMD Health News (Source: Medscape Infectious Diseases Headlines)
Tuesday 6 June 2023
Finding an effective way to prevent the spread of tick-borne illness such as Lyme disease has been quite challenging over the past several decades. Researchers have now developed a new approach that goes right to the place where a tick transmits disease: its salivary glands. (Source: Forbes.com Healthcare News)
Tuesday 6 June 2023
In 2019, the tick testing program, headed by Upstate Professor Saravanan Thangamani, PhD, received 1,921 tick samples from July through late October. About 25 percent of the ticks were found to carry Lyme disease. (Source: SUNY Upstate Medical)
Tuesday 6 June 2023
Public comments are still being accepted, but antibiotic treatment options for children are likely to be expanded to include the use of doxycycline. (Source: NYT Health)
Tuesday 6 June 2023
Ticks have evaded gene editing attempts for years, but scientists have finally figured out how to effectively modify their genome as they work to reduce disease transmission. (Source: WebMD Health)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. 100% free.
Tuesday 6 June 2023
Disease most common in women aged 61 to 65 Related items fromOnMedica Not tackling infections in homeless could spark epidemics Concerns over UK young adults ’ readiness for first sex Malaria cases rise sharply Texting can improve flu jab uptake HPV programme linked to dramatic fall in cervical disease (Source: OnMedica Latest News)
Tuesday 6 June 2023
(Canadian Medical Association Journal) Physicians and the public should be aware of the different presentations of Lyme disease, as people spend more time outside in the warmer weather and as areas in Canada where the black legged tick is found expand. Three articles in CMAJ (Canadian Medical Association Journal), which describe a fatal case in a 37-year-old man, atypical skin lesions in a 56-year-old woman and severe neurological symptoms in a 4-year-old boy, illustrate the diversity in presentations. (Source: EurekAlert! - Medicine and Health)
Tuesday 6 June 2023
White older women in south-west England appear most likely to contract the disease, a study suggests. (Source: BBC News | Health | UK Edition)
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Tuesday 6 June 2023
DR ELLIE CANNON: It is true Lyme disease can cause neurological problems, including dizziness and feeling off-balance, but it's rare for such symptoms to be the only complaint. (Source: the Mail online | Health)
Tuesday 6 June 2023
LYME disease is a bacterial infection spread to humans by infected ticks. The condition can be treated effectively if detected early, but a delay in recognising it can increase the risk of developing long-lasting symptoms. (Source: Daily Express - Health)
Tuesday 6 June 2023
Some tick-spread bacteria could be weaponized — but this would be a pretty useless choice. (Source: Washington Post: To Your Health)
Tuesday 6 June 2023
US researchers, who identified the gene editing method, said it could enable them to alter parts of a tick's DNA used to carry and transmit bacteria that causes diseases. (Source: the Mail online | Health)
Tuesday 6 June 2023
Steph Todd, from Thornbury in Gloucestershire, said people say her seizures make it look like she is 'possessed' and that she desperately wants treatment in the US. (Source: the Mail online | Health)
Tuesday 6 June 2023
(Washington State University) The next time a tick feeds on you, Washington State University researchers hope to make sure persistent arthritis caused by Lyme disease doesn't linger for a lifetime. (Source: EurekAlert! - Medicine and Health)
Tuesday 6 June 2023
We know far too little about Lyme and how to diagnose it, let alone have agreement between major advisory groups as to how to treat the disease. (Source: Forbes.com Healthcare News)
Tuesday 6 June 2023
The complex interplay of ticks, their habitats and hosts — along with changes in land use and climate — may be enabling the spread of the pathogens they carry.Knowable Magazine (Source: Medscape Infectious Diseases Headlines)
Tuesday 6 June 2023
As tick populations take hold permanently in large swaths of Canada, more people will be exposed and contract Lyme disease. (Source: CBC | Health)
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Tuesday 6 June 2023
With Lyme disease on the rise, people need to take special care to avoid tick encounters amid the COVID-19 crisis. (Source: Science - The Huffington Post)
Tuesday 6 June 2023
LYME DISEASE is on the rise according to Doctor Hilary on Lorraine with new cases of the disease everyday. What is it and how to know if you might have it? (Source: Daily Express - Health)
Tuesday 6 June 2023
Newcastle-under-Lyme MP Aaron Bell says a "breach of trust" has made the PM's position "untenable". #tory #newcastleunderlyme #confidenceletter #aaronbell (Source: Reuters: Health)
Tuesday 6 June 2023
LYME DISEASE is currently on the rise, as scientists have found there could be far more cases of the disease than previously estimated. What are the symptoms of Lyme disease? (Source: Daily Express - Health)
Tuesday 6 June 2023
Prepare for tick season by reviewing these five things to know about Lyme disease testing.CDC Expert Commentary (Source: Medscape Infectious Diseases Headlines)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. 100% free.
Tuesday 6 June 2023
Lexington sepsis and lyme disease diagnostics maker T2 Biosystems will need a new CEO to lead it through its ongoing financial struggles. T2 Biosystems (Nasdaq: TTOO) reported after markets closed Tuesday that CEO John McDonough will be stepping down from his role to become executive chairman of the company's board of directors. He will stay in the CEO role until the company hires his successor, according to a press release. McDon ough has been in the top job at T2 since 2007, leading T2 Biosystems… (Source: bizjournals.com Health Care:Biotechnology headlines)
Tuesday 6 June 2023
Valneva SE (Nasdaq: VALN; Euronext Paris: VLA), a specialty vaccine company, and Pfizer Inc. (NYSE: PFE) today reported further positive Phase 2 data for their Lyme disease vaccine candidate, VLA15. Based on these new results, Valneva and Pfizer plan to proceed with a three-dose primary series vaccination schedule in a planned Phase 3 clinical trial. (Source: World Pharma News)
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Tuesday 6 June 2023
New cases of tick-borne Lyme disease might top 8000 in 2019, researchers estimate Related items fromOnMedica Well over half of people have never had an STI test HPV programme linked to dramatic fall in cervical disease Should we have compulsory measles vaccination at school entry? Promise to end new HIV transmissions in England by 2030 Decision to give boys HPV jab will save thousands of lives (Source: OnMedica Latest News)
Tuesday 6 June 2023
SUNDAY, March 22, 2020 -- Where you put leaves raked from your yard last fall could affect your family's risk of bites from ticks that transmit Lyme disease-causing bacteria, a new study suggests. In areas where Lyme-causing ticks are prevalent,... (Source: Drugs.com - Daily MedNews)
Tuesday 6 June 2023
Kate Allen, 28, from Leicester, spotted raised bumps on her skin after walking her dog through long grass in the park in 30°C. Lyme disease is spread by tick bites. (Source: the Mail online | Health)
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Tuesday 6 June 2023
In March 2020, Laura Fitton, a 50-year-old entrepreneur in Massachusetts, had a high fever, sore throat, gastrointestinal issues, and loss of taste. But at the time, few of those symptoms were linked to COVID-19, so Fitton wasn’t eligible for a test. It took seven more months of persistent symptoms—including brain fog, swollen joints, fast heart rate, chills, and fatigue—for a doctor to order an antibody test. Although the test came back negative—perhaps because of how much time had passed since she had gotten sick—Fitton was relieved that a doctor was finally exploring the possibility of Long COVID, a little-understood condition in which people suffer symptoms long after their acute infection passes. [time-brightcove not-tgx=”true”] Two years afte...
Tuesday 6 June 2023
The biggest problem is that there is no way to test, unequivocally, for the presence of the bacteria that cause the disease. (Source: NYT Health)
Tuesday 6 June 2023
Supporting entrepreneurs can take many forms from grants to providing access to capital and from expanding their networks of mentors and peers to providing training that addresses both hard and soft skills. (Source: Forbes.com Healthcare News)
Tuesday 6 June 2023
LYME DISEASE is known as a form of arthritis caused by bacteria that is transmitted by ticks. If detected early it can often be treated effectively. What are the three signs you may have Lyme disease? (Source: Daily Express - Health)
Tuesday 6 June 2023
Researchers are seeking thousands of volunteers in the U.S. and Europe. (Source: ABC News: Health)
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Tuesday 6 June 2023
Pfizer and French biotech company Valneva are seeking volunteers to test their new vaccine against Lyme disease, which could protect both adults and kids as young as five from the tick-borne illness. (Source: CBC | Health)
Tuesday 6 June 2023
LYME DISEASE is a tick-borne infectious disease. Initial symptoms are usually mild, but if left untreated, more serious symptoms may reveal themselves. Have you spotted these serious signs? (Source: Daily Express - Health)
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Tuesday 6 June 2023
PET scans have demonstrated for the first time that only women appear to experienc...Read more on AuntMinnie.comRelated Reading: PET brain scans find links to PTSD severity in 9/11 responders PET tracers reveal long-term consequences of brain injuries Preclinical PET study offers better Alzheimer's detection Carbon-11 PET detects brain inflammation after Lyme disease C-11-based PET tracer could benefit arthritis patients (Source: AuntMinnie.com Headlines)
Tuesday 6 June 2023
Scientists from the National Institute for Health Research in London analysed 2,361 patients who were admitted to hospital with the bacterial infection between 1998 and 2015. (Source: the Mail online | Health)
Tuesday 6 June 2023
If successful, the vaccine would be the first against Lyme disease in the United States since Lymerix, which was discontinued in 2002 because of poor sales. (Source: Washington Post: To Your Health)
Tuesday 6 June 2023
FRIDAY, Aug. 16, 2019 -- The Infectious Diseases Society of America, the American Academy of Neurology, and the American College of Rheumatology have released a draft of their joint clinical practice guidelines for the management of Lyme... (Source: Drugs.com - Pharma News)
Tuesday 6 June 2023
(MedPage Today) -- Note that some links may require registration or subscription. A group of 23 state attorneys general led by Florida told a federal court Monday that the CDC does not have the legal authority to impose a nationwide transportation... (Source: MedPage Today Public Health)
Tuesday 6 June 2023
John St Julien, now 34, moved to east Africa in 2014 to launch a charity helping local children be educated. He soon started to feel run down but dismissed it as the pressure of his job. (Source: the Mail online | Health)
Tuesday 6 June 2023
A new Lyme disease could be available in the U.S. as early as 2025, as Pfizer has launched final clinical trials for its jab, VLA15. The company is aiming to apply for FDA approval in 2025. (Source: the Mail online | Health)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. 100% free.
Tuesday 6 June 2023
Three medical stories that we didn't cover, explained.Medscape (Source: Medscape Allergy Headlines)
Tuesday 6 June 2023
If the trial succeeds, the vaccine could be the first human vaccine for the tick-borne illness in the US in two decades.WebMD Health News (Source: Medscape PublicHealth Headlines)
Tuesday 6 June 2023
With an increase of nearly 10,000 cases of tickborne disease from 2016 to 2017 -- mostly lyme disease -- the National Institutes of Health announced a five-year plan to expand research and reduce infections. (Source: Health News - UPI.com)
MedWorm Message: Have you tried our new medical search engine? More powerful than before. 100% free.
Tuesday 6 June 2023
Vaccine maker Pfizer says it has begun Phase 3 clinical trial of its vaccine candidate against Lyme disease with French vaccine company Valneva SE. (Source: CNN.com - Health)
Tuesday 6 June 2023
LYME disease is a bacterial infection spread to humans by infected ticks. Ticks are tiny spider-like creatures found in woodland and heath areas. They feed on the blood of birds, mammals and humans. Feeling this sensation in your head could mean you have Lyme disease. (Source: Daily Express - Health)
Tuesday 6 June 2023
As global temperatures have risen in recent decades, so have the number of outbreaks of infectious diseases. SARS, MERS, Zika, West Nile, COVID-19, and now clusters of monkeypox and polio have all recently threatened public health. That’s no coincidence. In a study published in August in Nature Climate Change, researchers tried to understand the relationship between major environmental changes related to higher greenhouse gas emissions—including global warming, rising sea levels, storms, floods, drought, and heat waves—and the outbreaks of 375 human infectious diseases caused by viruses, bacteria, and other pathogens. They found that 58% of these public-health threats were fueled by climate change. [time-brightcove not-tgx=”true”] “The health impacts of ...
Tuesday 6 June 2023
First ever cases in Britain, says Public Health England Related items fromOnMedica Vaccine linked to earlier onset of seizures in Dravet syndrome Scans show severe brain damage in Zika-affected babies Lyme disease may be three times more common in UK than previously thought Single-dose malaria drug eliminates parasite from liver Common anti-parasitic could be new tool for malaria control (Source: OnMedica Latest News)
Tuesday 6 June 2023
A vaccine designed to protect against Lyme disease is being trialled and, if successful, could be available for use in 2025. Lyme disease is an infection spread by ticks. (Source: the Mail online | Health)
Tuesday 6 June 2023
Chronic Lyme disease occurs when a person who has already received treatment for Lyme disease continues to have symptoms in the long term. Learn more about this condition here. (Source: Health News from Medical News Today)
Tuesday 6 June 2023
Experts warn high seasonal temperatures are opening up new habitats for northern ticks in mountainous areas of southern states. But increasesd awareness may also fuel the rise. (Source: the Mail online | Health)
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Tuesday 6 June 2023
(CNN/CBS) — The climate crisis is making us more vulnerable to ticks in an unprecedented and growing threat to public health, according to a new report. Bacterial and protozoan tick-borne diseases doubled in the United States between 2004 and 2016, the report notes, and in 2017, more than 90% of the 60,000 vector-borne diseases in the United States were linked to these particular bloodsucking bugs. The warmer temperatures brought by the climate crisis, in addition to ecological changes and reforestation, have extended the bugs’ range into regions that had not seen certain types of ticks for many decades, if ever. And the report published in the New England Journal of Medicine Tuesday warns that we should be “bracing for the worst.” The lone star tick, a tick disting...
Tuesday 6 June 2023
(MedPage Today) -- Netflix's new documentary, Shania Twain: Not Just a Girl, follows the country singer from Nashville newcomer to international icon. Twain is the best-selling female country artist of all time, with three diamond-certified albums... (Source: MedPage Today Infectious Disease)
Tuesday 6 June 2023
Mother ’s fundraising campaign in Lyme Regis has been backed by likes of David AttenboroughEvie Swire was nine years old when she first heard the story of a woman who had lived near her home in Dorset and, in her own way, changed the world.Mary Anning was born into a humble family in Lyme Regis in 1799 and grew up hunting for fossils in the area ’s cliffs to supplement their meagre income. When she was 12, she and her brother discovered one of the first ichthyosaurus skeletons, and she would go on to make many other pioneering finds and become immensely knowledgeable in the emerging field of palaeontology.Continue reading... (Source: Guardian Unlimited Science)
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Tuesday 6 June 2023
According to a recent study, more than 14% of the world ’s population probably has, or has had, tick-borne Lyme disease – an infection that can cause long and debilitating symptoms. That number is set to rise too, as climate and environment changes continue to increase tick populations and distribution.To help prevent some of these cases, pharmaceutical company Pfizer and biotech company Valneva will soon be testing a new vaccine against Lyme disease with 6,000 volunteers across Europe and in the US.Madeleine Finlay speaks to Dr Eoin Healy about what Lyme disease is and how the vaccine works, and hears from a special guest about their own experience of getting ill with the disease.Archive: BBC News, TODAYContinue reading... (Source: Guardian Unlimited Science)
Tuesday 6 June 2023
Lyme disease is the most common illness spread by ticks in North America and Europe. View Lyme disease symptoms, treatments and prevention tips. (Source: CNN.com - Health)
Tuesday 6 June 2023
TUESDAY, Sept. 20, 2022 -- They look so cute, grazing quietly in your backyard. But the overpopulation of white-tailed deer across the Northeastern United States could help spread Lyme disease and another tick-borne illness, anaplasmosis, especially... (Source: Drugs.com - Daily MedNews)
Tuesday 6 June 2023
Singer Justin Bieber says he has Lyme disease, revealing his condition Wednesday in an Instagram post addressing comments people have made about his appearance in recent months. (Source: WebMD Health)
Tuesday 6 June 2023
Meghan Bradshaw, now 29 and from Charlotte in North Carolina, was described by doctors as the 'worst case' of Lyme disease they had seen. She now says she is a 'bionic woman'. (Source: the Mail online | Health)
Tuesday 6 June 2023
The pensioner, from Castelo Branco, Portugal, went to hospital with excruciating pains in his chest and extremely low blood pressure. Justin Bieber announced he had the illness last week. (Source: the Mail online | Health)
Tuesday 6 June 2023
A new study suggests the overpopulation of white-tailed deer across the Northeastern U.S. could help spread Lyme disease, especially in suburban areas. (Source: WebMD Health)
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Tuesday 6 June 2023
Engineers with the University of Cincinnati have created a tiny portable lab that plugs into your phone, connecting it automatically to a doctor's office through a custom app UC developed. The lab the size of a credit card can diagnose infectious diseases such as coronavirus, malaria, HIV or Lyme disease or countless other health conditions like depression and anxiety. (Source: eHealth News EU)
Tuesday 6 June 2023
Is whole blood-RT-PCR useful as a diagnostic aid for early Lyme disease when done in conjunction with serology testing?American Journal of Clinical Pathology (Source: Medscape Today Headlines)
Tuesday 6 June 2023
(Frontiers) A preclinical in vitro study shows that selected plant-based herbal medicines, especially Ghanaian quinine and Japanese knotweed, work better than antibiotics against the bacterium that causes Lyme disease. These findings represent an important step towards the development of treatments that might be better tolerated and more effective than the current standard of care. (Source: EurekAlert! - Infectious and Emerging Diseases)
Tuesday 6 June 2023
This review provides an approach to patients with neurological disorders in whom a diagnosis of Lyme neuroborreliosis is being considered. What does and does not constitute nervous system disease?Brain (Source: Medscape Today Headlines)
Tuesday 6 June 2023
(Columbia University) A new model based on 17 years of data can help predict the trajectory of where Lyme disease will spread. Identifying high-risk areas can lead to surveillance in counties and areas where infections are likely to emerge. It also allows authorities to alert physicians and the public, which can lead to early treatment, when it is most effective. (Source: EurekAlert! - Medicine and Health)
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Tuesday 6 June 2023
Headlines on COVID-19 and monkeypox underscore the importance of understanding infectious diseases and how they're transmitted. Scientists are studying these diseases, such as hand, foot and mouth disease and Lyme disease, to gain insights into how … (Source: NSF News)
Tuesday 6 June 2023
Credit: United Nations By Thalif DeenUNITED NATIONS, Mar 24 2020 (IPS) When US President Donald Trump repeatedly characterized the fast-spreading COVID-19 as a “Chinese virus” last week, it prompted some white supremacists to resurrect an age old ethnic slur against Chinese and East Asians: the “Yellow Peril” which, in a bygone era, was touted as a xenophobic threat to the Western world. But Tendayi Achiume, UN Special Rapporteur on Contemporary Forms of Racism, Racial Discrimination and Xenophobia, is highly critical of the racist interpretation to a disease which has claimed over 16,500 deaths worldwide and accounted for more than 378,000 infections, with the epicenter shifting from China to Europe. Singling out Trump, she said: it’s dismaying, however, “to witness State off...
Tuesday 6 June 2023
And if this was Bell ’s palsy, why wasn’t there improvement after a full year? (Source: NYT Health)
Tuesday 6 June 2023
WASHINGTON — Blood tests for the coronavirus could play a key role in deciding whether millions of Americans can safely return to work and school. But public health officials warn that the current “Wild West” of unregulated tests is creating confusion that could ultimately slow the path to recovery. More than 70 companies have signed up to sell so-called antibody tests in recent weeks, according to U.S. regulators. Governments around the world hope that the rapid tests, which typically use a finger-prick of blood on a test strip, could soon ease public restrictions by identifying people who have previously had the virus and have developed some immunity to it. But key questions remain: How accurate are the tests, how much protection is needed and how long will that protec...
Tuesday 6 June 2023
Meghan Bradshaw has had 16 joint reconstructions and eight joint replacements, all before age 30. This is due to a late diagnosis of Lyme disease, which is a tick-borne illness that can be treated and cured if detected early. (Source: WebMD Health)
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Tuesday 6 June 2023
(Virginia Tech) With a $661,216 grant from the Steven& Alexandra Cohen Foundation, Brandon Jutras, an assistant professor of biochemistry in the Virginia Tech College of Agriculture and Life Sciences, will study Lyme arthritis, including the cellular component that contributes to it. (Source: EurekAlert! - Infectious and Emerging Diseases)
Tuesday 6 June 2023
Attention and funding for research into mononucleosis, HIV, Lyme, Ebola, Sars and other infections have historically been limited – but long Covid changed thatRead the Guardian ’s new series, Living with long CovidAs the coronavirus grew from a fleeting concern to a full-blown panic, Lili Lim started to hear about people for whom the illness lasted weeks or even months. There were news stories of young people that couldn ’t shake their fatigue or cognitive malaise, of folks who had to quit their job due to debilitating exhaustion.For Lim, the symptoms were frighteningly recognizable.Continue reading... (Source: Guardian Unlimited Science)
Tuesday 6 June 2023
This case describes an unusual dermatologic presentation of Lyme disease, borrelial lymphocytoma, which is rare in the US but more common in Europe.Journal of Medical Case Reports (Source: Medscape Today Headlines)
Tuesday 6 June 2023
Consumers can use the tests to detect Lyme disease, vitamin D levels, thyroid function, and sexually-transmitted infections. (Source: mobihealthnews)
Tuesday 6 June 2023
(Entomological Society of America) While the prevalence of Lyme disease and other illnesses spread by ticks has steadily increased in the United States over the past 20 years, a new study of the state of American tick surveillance and control reveals an inconsistent and often under-supported patchwork of programs across the country. (Source: EurekAlert! - Infectious and Emerging Diseases)
Tuesday 6 June 2023
Many patients who have had Lyme disease struggle with cognitive challenges, even after treatment. This new imaging study shows changes in white matter that might explain these symptoms.Medscape Medical News (Source: Medscape Psychiatry Headlines)
Tuesday 6 June 2023
Discussion Bradycardia is a heart rate below what the lowest value that is normal for age. Infants and children have higher heart rates that slowly decrease with age to adult levels. It is usually noted as an incidental finding because of increased vagal tone. Reasons for cardiology referral include associated heart murmur, syncope especially if associated with exercise or unusual triggers, other signs such as chest pain or palpitations, family history of sudden cardiac death, congenital heart disease or familial heart disease, bradycardic medication use, or unusual symptoms associated with the concern. Severe bradycardia that causes poor cardiac output is a medical emergency. Fortunately most children have mild bradycardia which may have no symptoms or can manifest as dizziness, syncope, ...
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Tuesday 6 June 2023
People who have been treated for Lyme disease, but continue to have symptoms, have changes in their brains that confirm the memory and concentration problems many of them have reported, a new study has found. (Source: WebMD Health)
Tuesday 6 June 2023
(CNN) — After more than three months of shutdowns, mandatory quarantines, self-imposed exile from society and working from home, nature-lovers looking for a well-earned breath of fresh air could face a possible collision course between coronavirus and tick-borne illnesses this summer. A “perfect storm,” warns Eva Sapi, a University of New Haven biology professor and group director for the Lyme Disease Research Group. Noting the mild winter on the East Coast, Sapi says, “We do have a bad year for the ticks.” Hikers, campers and anyone else eager for an escape could “just explode into the outdoors. And there may not be the same thoughtful approach” to preventing exposure, explains Dr. Sorana Segal-Maurer, director of the Dr. James J. Rahal, Jr. Divi...
Tuesday 6 June 2023
(Source: MayoClinic.com Full Feed)
Tuesday 6 June 2023
by Sarah Elizabeth Adler, AARP, Updated July 14, 2020 | ... En espa ñol | Ticks: They're the tiny pests that stop outdoor fun in its tracks — and experts say they stay active well into fall, making ... (Source: AARP.org News)
Tuesday 6 June 2023
A genetic test would be an improvement on current FDA-approved tests, which identify antibodies that can take weeks to emerge. (Source: Washington Post: To Your Health)
Tuesday 6 June 2023
SATURDAY, Aug. 1, 2020 -- Summer means higher odds of getting Lyme disease, so know how to avoid it, health experts say. Lyme disease is caused by a bacterium carried by some ticks and, if left untreated, can cause severe health problems. Ticks can... (Source: Drugs.com - Daily MedNews)
Tuesday 6 June 2023
Pfizer stock pulled back in mid-December, but remains above its key moving averages, on a series of good news for its Covid and respiratory syncytial virus vaccines. X This month, alone, the Food and Drug Administration granted a priority review for Pfizer's (PFE) RSV vaccine in older adults. RSV…#molnupiravir #bntx #comirnaty #ibd #compositeratings #lyme #pfizer #allisongatlin #technicalanalysis #fdamullsits (Source: Reuters: Health)
Tuesday 6 June 2023
Platinum Seal allows donors to focus on progress and results for top Lyme disease organization(PRWeb August 10, 2020)Read the full story at https://www.prweb.com/releases/global_lyme_alliance_reaches_guidestars_highest_seal_of_transparency/prweb17313403.htm (Source: PRWeb: Medical Pharmaceuticals)
Tuesday 6 June 2023
Study shows that ticks infected with pathogens carrying Lyme disease prefer to bite humans in different areas than uninfected ticks. (Source: SUNY Upstate Medical)
Tuesday 6 June 2023
Credit: United Nations Office for Disaster Risk Reduction (UNDRR)By Lawrence SurendraBANGKOK, Thailand, Aug 24 2020 (IPS) The COVID 19 Pandemic continues relentlessly. Deaths approaching a million globally, 22 million infected and growing. Brazil, India, the US and Russia accounting for almost 50% of the total cases in the world. Medically the promise of a vaccine is given as signs of hope; what surprises awaits us when such a vaccine is available, would be another story. Economically, to address the uncertainty and the grim future ahead, the UN, some governments and even Joe Biden the US Presidential hopeful, are waving “Build Back better” as ways to achieve ‘a new normal’ out of the current pandemic. “Build Back Better” emerged out of the 3rd International Conference on Disa...
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Tuesday 6 June 2023
Support for funding spearheaded by Sens. Schumer, Gillibrand and Rep. Katko (Source: SUNY Upstate Medical)
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Tuesday 6 June 2023
DR ELLIE CANNON: Today's reader would like to know whether a recent bout of lyme disease could have caused their itchy skin and is there a remedy to alleviate the annoying symptoms. (Source: the Mail online | Health)
Tuesday 6 June 2023
Patients with Lyme neuroborreliosis, a late-stage manifestation of Lyme disease, may develop psychiatric illness, but new research suggests that when symptoms do develop, they tend to resolve within a year.Medscape Medical News (Source: Medscape Internal Medicine Headlines)
Tuesday 6 June 2023
BBB Model Used to Study How Lyme neuroborreliosis (LNB) penetrates the Brian.Yvonne Adams, Anne Skovsbo Clausen, Peter Østrup Jensen, Malin Lager, Peter Wilhelmsson, Anna J. Henningson, Per-Eric Lindgren, Daniel Faurholt-Jepsen, Helene Mens, Peter Kraiczy, Kasper Nørskov Kragh, Thomas Bjarnsholt, Andreas Kjaer, Anne-Mette Lebech, Anja R. Jensen,3D blood-brain barrier-organoids as a model for Lyme neuroborreliosis highlighting genospecies dependent organotropism, iScience, Volume 26, Issue 1, 2023, 105838, ISSN 2589-0042, https://doi.org/10.1016/j.isci.2022.105838.Image: LNB Penetrating the BBB (green Fluorescence)Researchers discovered Borrelia spp. exposure triggers a loss of tight junctions. Organoid structural integrity is significantly reduced after Borrelia spp. exposure (Sourc...
Tuesday 6 June 2023
The newly identified protein acts like an early warning signal to the immune system when exposed to the bacteria at causes Lyme disease. (Source: Yale Science and Health News)
Tuesday 6 June 2023
Early Lyme Disease as Manifested by Erythema Migrans: Developing Drugs for Treatment (Source: FDA Center for Drug Evaluation and Research - What's New)
Tuesday 6 June 2023
(University of Illinois at Urbana-Champaign, News Bureau) By drawing from decades of studies, scientists created a timeline marking the arrival of black-legged ticks, also known as deer ticks, in hundreds of counties across 10 Midwestern states. They used these data - along with an analysis of county-level landscape features associated with the spread of ticks - to build a model that can predict where ticks are likely to appear in future years. (Source: EurekAlert! - Infectious and Emerging Diseases)
Tuesday 6 June 2023
Shania Twain is back on her horse with “Queen Of Me,” her first album in more than five years. The Canadian country-pop superstar marks her comeback with the 12-track set, led by “Waking Up Dreaming,” her first single since 2017, and her latest, “Giddy Up!”. A five-time Grammy Award winner, Queen…#shaniatwain #queenofme #wakingupdreaming #grammyaward #republicnashville #twain #lyme #applemusic #paisleypark #applemusics (Source: Reuters: Health)
Tuesday 6 June 2023
Crowdfunder led by schoolgirl raises £70,000 for sculpture of pioneering palaeontologist in Lyme Regis, DorsetA statue toMary Anning, a fossil hunter and palaeontologist once “lost to history” but now considered a significant female force in science, is finally to be erected after a crowdfunding campaign by a teenage girl.Evie Swire, 13, was nine years old when she first heard of Anning, who was born into a humble family in 1799 near Evie ’s Lyme Regis home in Dorset. The schoolgirl was outraged to discover there was no statue.Continue reading... (Source: Guardian Unlimited Science)
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Tuesday 6 June 2023
(MedPage Today) -- The ChatGPT artificial intelligence chatbot provided largely appropriate responses to simple cardiovascular prevention questions, though some answers lacked context and may be harmful. (JAMA) People conceived from assisted reproductive... (Source: MedPage Today Cardiovascular)
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Tuesday 6 June 2023
Special 50p coins will feature some of the Jurassic creatures discovered by 19th-century palaeontologistOne of the most terrifying Jurassic sea creatures is to appear on commemorative 50p coins to celebrate the work of thepioneering fossil hunter Mary Anning.The temnodontosaurus coins will shine a light on the 19th-century palaeontologist, who made a series of discoveries near her home in Lyme Regis, Dorset.Continue reading... (Source: Guardian Unlimited Science)
Tuesday 6 June 2023
Around 3,500 patients will be pulled from the Phase III study due to violations of Good Clinical Practice (GCP) rules, which refer to ethical and scientific standards for clinical trials. (Source: the Mail online | Health)
Tuesday 6 June 2023
(Columbia University Irving Medical Center) With a $16 million gift from the Steven& Alexandra Cohen Foundation, Columbia will open a center for Lyme and other tick-borne diseases this summer, offering patients specialized care and expanding research at a national level. (Source: EurekAlert! - Infectious and Emerging Diseases)
Tuesday 6 June 2023
stock plummeted Friday after Pfizer (PFE) said it will drop roughly half of the participants enrolled in the companies' Lyme disease vaccine study. The decision comes after Pfizer found violations of "good clinical practice" rules at study sites run by a third-party operator. These rules safeguard…#pfe #lyme #gcp #valneva #pfizer #phase3 #clinicaltrialsgov #vla15 #marketsmithcom #apatentcliffiscoming (Source: Reuters: Health)
Tuesday 6 June 2023
The modified approach for detecting exposure to Borrelia burgdorferi uses two enzyme immunoassays, with no need for Western blot.FDA Approvals (Source: Medscape Emergency Medicine Headlines)
Tuesday 6 June 2023
(Source: Reuters: Health)
Tuesday 6 June 2023
UK cohort study (n=8.4 million) found that the number of cases of Lyme disease has increased rapidly since 2001, resulting in an incidence of 12.1 per 100,000 per year in 2012. Authors state that this should lead to increased awareness and the need for preventative measures. (Source: Current Awareness Service for Health (CASH))
Tuesday 6 June 2023
"Outdoorsy" Noah is hoping to crowdfund £ 40,000 to pay for private treatment for Lyme disease saying he "doesn't have a life". (Source: Daily Express - Health)
Tuesday 6 June 2023
Listen: Mayo Clinic Radio 8/10/19 On the Mayo Clinic Radio podcast, Dr. Gregory Poland, a Mayo Clinic infectious diseases and vaccine expert, gives an update on infectious disease hot topics, including Lyme disease, the ongoing concern about measles, the hope for a universal flu vaccine and new age guidelines for the HPV vaccine. Also on the podcast, Dr. John Lieske explains how kidney stones form and how [...] (Source: News from Mayo Clinic)
Tuesday 6 June 2023
Emily Cahill, a former software engineer at Google, said being laid off was like a "blessing." Emily Cahill Emily Cahill, a software engineer, was one of 12,000 people laid off by Google in January. She told Insider she's starting a wellness club after struggling with Lyme disease in college.…#cahill #google #cahillemilycahill #lyme #emilycahill #wholehealingclub (Source: Reuters: Health)
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Tuesday 6 June 2023
LYME disease may have an innocent sounding name, but it ’s a nasty condition transmitted by ticks which, left untreated, can lead to severe health problems. Here are three parts of body you should always check after visiting grassy and woodland areas, as well as other symptoms you should look out for. (Source: Daily Express - Health)
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Tuesday 6 June 2023
The warming world can be a hospitable place for blacklegged ticks, which carry the bacteria that cause Lyme disease. They thrive in temperatures at or above 7.2º C (45º F) and at 82% or greater humidity (the warmer and wetter, the better). As climate change steadily bakes the planet—with shorter, milder winters and longer, hotter summers and springs—the range of places with those conditions is growing. However, climate change is actually making some parts of the world less hospitable to ticks. Extreme weather leads to droughts (which causes ticks to dry out and die) as well as a lack of snow cover (which the species needs to provide insulation as they spend the winter burrowed beneath leaf cover). [time-brightcove not-tgx=”true”] Is climate change a net ...
Tuesday 6 June 2023
LYME disease is a bacterial infection which is spread to humans via tick bites. The most notable symptom is the rash that develops, but not all symptoms associated with the condition necessarily point to Lyme disease. (Source: Daily Express - Health)
Tuesday 6 June 2023
Public finally able to see 3D remains of plesiosaur discovered on Lyme Regis beach 16 years agoAt first when Raffle the dog began scratching at something on the beach at Lyme Regis, Tracey Barclay thought he had probably found a boring old stick or stone.But when she looked closer, Barclay realised Raffle had happened upon something much more interesting – the remains of a plesiosaur, a marine reptile that swam off modern day Dorset 200m years ago.Continue reading... (Source: Guardian Unlimited Science)
Tuesday 6 June 2023
Two newly reported cases of fatal Lyme carditis serve as a reminder of the importance of prompt identification and treatment of this potentially life-threatening infection.Reuters Health Information (Source: Medscape Medical News Headlines)
Tuesday 6 June 2023
Babesiosis, which can cause flulike symptoms, could be spreading because of rising temperatures and the growing deer population. (Source: NYT Health)
Tuesday 6 June 2023
I’m always so proud of what our union stands for and what we can achieve when we stand together. But sometimes there are days when that’s particularly true – and earlier this week I had one of those days. It started early on a picket line at Whiston Hospital. The strikers – employed by Compass – have a simple demand, to get the same pay and conditions as those they work alongside in our NHS. Their energy, their passion and their unwillingness to give in are truly inspiring. These are the people who keep our NHS – our nation’s greatest achievement – running each day. They clean, they cook and they make sure patients are where they’re meant to be. They embody the incredible values of the NHS and our union, and it’s time that Compass (a company whic...
Tuesday 6 June 2023
Ruby McMahon and Eve Slemp of East Lyme, Conn. Ms. McMahon went “TikTok sober” about a year ago, while Miss Slemp is a regular user of the app. This month, the company announced a new 60-minute “daily screen time limit” for users under 18. But for most young users, staying on the app takes just a…#rubymcmahon #eveslemp #eastlyme #conn #missslemp #tiktok #eastlymehighschool #connecticut #bytedance #beijing (Source: Reuters: Health)
Tuesday 6 June 2023
Tuesday 6 June 2023
An infected black-legged tick can transmit babesiosis and other infections Tick season is underway in much of the U.S. This season, another tick-borne disease is on the list of concerns. That's because the Centers for Disease Control and Prevention has found a significant increase in reported cases of babesiosis(bah-beez-E-oh-sis) infection in eastern parts of the U.S. "Babesiosis is another tick-borne disease that we hear about, in addition to Lyme disease, anaplasmosis and others," says Dr. Bobbi… (Source: News from Mayo Clinic)
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Tuesday 6 June 2023
For now, the only prevention lies in avoiding tick contact but one company, Valneva, is working fervently to develop what they believe will be the world ’s first vaccine against Lyme’s disease. (Source: Forbes.com Healthcare News)
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Tuesday 6 June 2023
The presence of Borrelia garinii, a cause of Lyme disease, was confirmed in the U.S. using genomic sequencing.Emerging Infectious Diseases (Source: Medscape Today Headlines)
Tuesday 6 June 2023
LYME disease is a bacterial infection which could lead to severe physical and mental problems if not diagnosed at an early stage. Spotting the early warning signs will ensure prompt treatment and noticing this peculiar feeling in the head could mean you're at risk. (Source: Daily Express - Health)
Tuesday 6 June 2023
My husband is 81 years old and I am 68. He was a banking professional for many years and retired in 2007. He always handled our finances but became ill a few years ago. I took it upon myself to sort out our tax situation and was appalled to find he had not done our taxes after 2018. He got sick in…#treasurydepartment #bradgould #floridabar #comiter #basemanbraunllp #stuart #fla #lethasgrittamcdowell #hooklaw #lyme (Source: Reuters: Health)
Tuesday 6 June 2023
Lyme disease experts are not surprised by CDC's failure to ensure quick diagnosis of COVID-19. It's failed for 25 years to fix a broken Lyme test. (Source: Forbes.com Healthcare News)
Tuesday 6 June 2023
Chris Rose lost ten years of his health—not to mention his gallbladder—to a single tick bite. The tick bit in 2010 and Rose, now a 50-year-old network engineer in Chapel Hill, N.C., thought little of it at the time. “It was one of those lone star ticks,” he says, “and I just picked it off me. It wasn’t a big deal.” Before long, however, Rose began developing crushing chest pains, abdominal discomfort, diarrhea, and other symptoms. Doctors screened him for heart disease, irritable bowel syndrome, and gallstones, and even removed his gallbladder to see if that might ease the intestinal symptoms. But nothing worked, and the symptoms persisted for a decade. [time-brightcove not-tgx=”true”] Finally, in 2020, he visited Dr. Sarah McGill, a g...
Tuesday 6 June 2023
BOSTON (CBS) — As Massachusetts continues to fight the coronavirus pandemic, the public has plenty of questions. Dr. Mallika Marshall answered some of those sent to WBZ-TV’s Facebook, Instagram and Twitter accounts. With the upcoming season, we already have troubles with ticks and Lyme disease and mosquitoes and their diseases. How is the coronavirus going to affect this problem? – Ken from north of Boston Coronavirus is not spread by mosquitoes or ticks, but you’re right, we still have to protect ourselves from insect-borne diseases like Lyme Disease and West Nile Virus. So I would do what we normally do to avoid these insects: use protective clothing and insect repellant and avoid the times of day and locations where they thrive. If I self-isolate for more than two ...
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Tuesday 6 June 2023
Lyme, Connecticut Dennis Carbo Two circa-1760 houses make up this pastel-painted five-bedroom home: the site's original gambrel Colonial and a center-chimney Colonial moved from a town nearby. The house has antique details, a library, a tavern, a music room, and a connecting eat-in kitchen…#lyme #connecticut #denniscarbo #colonial #connecticutriver #paulsmyth #williampitt #sotheby #internationalrealty #albion (Source: Reuters: Health)
Tuesday 6 June 2023
CORONAVIRUS symptoms have been shown to range from a dry cough to conjunctivitis, but some of these symptoms are also linked to other conditions such as Lyme disease. How can you tell the difference between COVID-19 and Lyme disease? (Source: Daily Express - Health)
Tuesday 6 June 2023
Lyme is Moderna ’s first attempt at creating a vaccine for a bacterial infection. (Source: Forbes.com Healthcare News)
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Tuesday 6 June 2023
Title: What Happens if You Go Untreated for Lyme Disease?Category: Diseases and ConditionsCreated: 6/17/2020 12:00:00 AMLast Editorial Review: 6/29/2020 12:00:00 AM (Source: MedicineNet Arthritis General)
Tuesday 6 June 2023
A study by the Yale School of Public Health found that Powassan virus, dubbed 'Lyme disease's deadly cousin', is being detected in clusters in Connecticut, New York State and Maine. (Source: the Mail online | Health)
Tuesday 6 June 2023
With no vaccine against Lyme right now, the author and his colleagues are working to create seasonal protection. (Source: Washington Post: To Your Health)
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Tuesday 6 June 2023
Upstate is specifically looking for a minimum of 100 participants ages 12 to 17 for the two-year study. (Source: SUNY Upstate Medical)
Tuesday 6 June 2023
LYME DISEASE is normally harmless, but if it is left untreated it can be deadly. How do you get Lyme disease? (Source: Daily Express - Health)
Tuesday 6 June 2023
La enfermedad de Lyme est á en aumento. ¿Cómo puede prevenirla?¿Cuáles son los síntomas y qué debe hacer si cree que usted o su perro la padecen? (Source: FDA Center for Drug Evaluation and Research - What's New)
Tuesday 6 June 2023
(University of Arizona College of Engineering) In her Little Sensor Lab, University of Arizona professor Judith Su is working to sense single molecule amounts of 'anything worth sensing' -- including biomarkers for cancer, Alzheimer's disease, Lyme disease and even COVID-19. (Source: EurekAlert! - Medicine and Health)
Tuesday 6 June 2023
A late diagnosis or misdiagnosis of Lyme disease can lead to serious long-term health problems. (Source: Daily Express - Health)
Tuesday 6 June 2023
(University of California - San Francisco) Ticks live dangerous lives, spending most of their time questing for a host across wildly different habitats and seasons. Once they encounter a reptile, bird, or a mammal like us, they become intimately connected with it -- and all of its bacteria and viruses -- for days on end. Though ticks are notorious for transmitting pathogens such as the Lyme disease bacterium, how does their immune system keep them safe from contracting pathogens themselves? (Source: EurekAlert! - Infectious and Emerging Diseases)
Tuesday 6 June 2023
In severe cases Lyme disease can cause lasting joint pain, and nerve and heart problems. (Source: Daily Express - Health)
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Tuesday 6 June 2023
(PLOS) A new analysis suggests that north-south differences in ticks' host choice, density, and host-seeking behaviors may explain why Lyme disease is more prevalent in the northeastern U.S. than in the southeast. Howard Ginsberg of the U.S. Geological Survey's Patuxent Wildlife Research Center and colleagues present these findings in an article publishing January 28th in the open-access journalPLOS Biology. (Source: EurekAlert! - Infectious and Emerging Diseases)
Tuesday 6 June 2023
Toolkit and resources for local authorities and other stakeholders to raise awareness of the potential risks created by ticks and tick-borne disease in England. 24 April 2023Added co-branded resources. 4 April 2023Updated tick awareness leaflet, poster and toolkit. Removed co-branded resources. (Source: Current Awareness Service for Health (CASH))
Tuesday 6 June 2023
Discussion Dengue is an important arboviral infection that affects about 40% of the world population. It is found mainly in topical and subtropical areas of the world mainly in developing countries but it range is spreading including the United States. A review of common arboviruses can be found here. It is a flaviavirus with 4 distinct serotypes named DENV-1 through DENV-4 and is spread by A. aegypti a day biting mosquito. Infection with one serotype confers immunity to that serotype but not the others. It does offer some protection for cross-infection but this only lasts a few months. Incubation period is 3-14 days with an average of 7 after exposure. A primary infection is usually benign. A second infection with another serotype or multiple infections with different serotypes can caus...
Tuesday 6 June 2023
It is estimated that 476,000 people in the US are diagnosed and treated for Lyme disease annually.WebMD Health News (Source: Medscape Infectious Diseases Headlines)
Tuesday 6 June 2023
An Ontario health advocacy group is calling for more action to protect children from the harmful impacts of climate change. The group says cases of asthma, heat stroke and Lyme disease could all be on the rise in the coming decades. (Source: CBC | Health)
Tuesday 6 June 2023
After a mild winter in the U.S., scientists are watching to see if there will be an uptick in ticks this year (Source: ABC News: Health)
Tuesday 6 June 2023
Recently, the FDA cleared several Lyme disease serologic assays with new indications for use, allowing for an EIA rather than western immunoblot assay as a confirmatory test.Morbidity & Mortality Weekly Report (Source: Medscape Today Headlines)
Tuesday 6 June 2023
Experts say cases of babesiosis are increasing along with Lyme disease. Pay attention to these symptoms. (Source: Healthy Living - The Huffington Post)
Tuesday 6 June 2023
A novel PET imaging technique has uncovered high levels of ischemia in patients...Read more on AuntMinnie.comRelated Reading: PET/MRI sheds light on cerebral vascular risk factors Flortaucipir-PET shows tau accumulation after one TBI PET, MRI show physical activity aids brain health Carbon-11 PET detects brain inflammation after Lyme disease SNMMI: Cerebrovascular risk tied to Alzheimer's disease (Source: AuntMinnie.com Headlines)
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Tuesday 6 June 2023
Experts say cases of babesiosis are increasing along with Lyme disease. Pay attention to these symptoms. (Source: Healthy Living - The Huffington Post)
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Tuesday 6 June 2023
(NEW YORK) — Justin Bieber says that he has been battling Lyme disease. In an Instagram post on Wednesday, the pop star wrote that “it’s been a rough couple years but (I’m) getting the right treatment that will help treat this so far incurable disease and I will be back and better than ever.” Lyme disease is transmitted by Ixodes ticks, also known as deer ticks. Lyme can cause flu-like conditions, neurological problems, joint paint and other symptoms. “While a lot of people kept saying justin Bieber looks like (expletive), on meth etc. they failed to realize I’ve been recently diagnosed with Lyme disease, not only that but had a serious case of chronic mono which affected my, skin, brain function, energy, and overall health,” Bieber wrote. Th...
Tuesday 6 June 2023
MONDAY, May 1, 2023 -- Most children with Lyme disease experience full resolution of symptoms, according to a study published online March 30 in Pediatric Research. Maureen Monaghan, Ph.D., from The George Washington University School of Medicine... (Source: Drugs.com - Pharma News)
Tuesday 6 June 2023
This cluster of Lyme disease cases in North Carolina indicates that the disease may be expanding further south.Morbidity & Mortality Weekly Report (Source: Medscape Today Headlines)
Tuesday 6 June 2023
Learn about the neurological manifestations of Lyme disease, and the role of the pharmacist in its treatment and prevention.U.S. Pharmacist (Source: Medscape Today Headlines)
Tuesday 6 June 2023
As warm weather sends people outdoors, some are encountering tenacious pests. Ticks go for blood in the hardest-to-reach places on the human body and put you at risk for Lyme disease. Here's what you need to know about staying tick-safe. (Source: CNN.com - Health)
Tuesday 6 June 2023
An interactive map reveals where in England Lyme disease has infected the most people. Nearly three-quarters (72.6 per cent) of the country logged a case of the bacterial infection last year. (Source: the Mail online | Health)
Tuesday 6 June 2023
(NEW YORK) — WNBA MVP Elena Delle Donne was shocked and hurt when her request to be medically excused for the season was denied by an independent medical panel. Having battled Lyme disease for more than a decade and now taking 64 pills a day, she thought she was definitely going to be considered high-risk to get severe illness if she contracted the coronavirus. The panel of independent doctors the league and union agreed upon to make that decision thought otherwise, ruling Monday that she was not “high risk, and should be permitted to play in the bubble.” The disease is not included on the Centers for Disease Control and Prevention’s list of underlying conditions that could put someone at an increased risk for severe illness from COVID-19. The Washington Mystics st...
Tuesday 6 June 2023
Join experts Drs Felicia Chow and Karen Roos as they discuss the diagnosis and treatment of Lyme meningitis and other emerging neuroborreliosis.Medscape (Source: Medscape Today Headlines)
Tuesday 6 June 2023
Lyme disease is on the rise. How can you prevent it? What are the symptoms, and what should you do if you think you or your pet have it? (Source: FDA Center for Drug Evaluation and Research - What's New)
Tuesday 6 June 2023
US Biologic has received conditional licensure from the USDA for its Lyme disease vaccine for mice, which will allow it to take the product to market. (Source: bizjournals.com Health Care:Physician Practices headlines)
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Tuesday 6 June 2023
A new model helps identify areas with high populations of the ticks that carry Lyme disease, a study published Tuesday by the Proceedings of the Royal Society B found. (Source: Health News - UPI.com)
Tuesday 6 June 2023
SATURDAY, May 13, 2023 -- The best way to prevent Lyme disease is to not get bitten by a tick, or to get it off your body within 24 hours. That doesn ’t mean you shouldn’t enjoy the great outdoors. Experts from Tufts University School of Medicine... (Source: Drugs.com - Daily MedNews)
Tuesday 6 June 2023
Researchers say tick-borne disease ‘is everywhere’ with 8,000 diagnoses likely in 2019Cases of Lyme disease in the UK may be three times higher than previous estimates, according to new research.After analysing the anonymous medical records of 8.4 million people from across the UK, scientists forecast that the total number of Lyme disease diagnoses in the UK could top 8,000 in 2019, compared withpreviousestimates of between 2,000 and 3,000 annual diagnoses.Continue reading... (Source: Guardian Unlimited Science)
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Tuesday 6 June 2023
Canadians need to be more vigilant against the rapid growth in the number of Lyme disease cases across the country, as climate change fuels an explosion of tick populations and new hotspots for infection continue to emerge from coast to coast. (Source: CBC | Health)
Tuesday 6 June 2023
DR MARTIN SCURR: Pat Toovey from Norfolk found a tick on his wife's back two years ago and she is constantly in pain and struggles to get out of bed. He fears she has Lyme disease. (Source: the Mail online | Health)
Tuesday 6 June 2023
THURSDAY, May 25, 2023– Robert Weymouth, 58, of Portland, Maine, died this year because of a tick bite. You've likely heard of Lyme disease and the problems it can cause when passed to a human through the bite of a deer tick. But Lyme... (Source: Drugs.com - Daily MedNews)
Tuesday 6 June 2023
NEW YORK (CBS) – The United States has seen a big rise in the number of Lyme disease cases. A new study finds that the number of Americans diagnosed with the illness more than doubled over the past decade. Researchers at FAIR looked at private health insurance claims from 2007 to 2018. They found the biggest increase was in urban areas where claims for Lyme disease increased by more than 120%. Read The Report (PDF) “Lyme disease is the nation’s predominant tick-borne disease, and it is growing,” FAIR said in its report. Massachusetts was among the Top 10 states with the highest percentages of insurance claims for Lyme. The infection is spread through tick bites and can affect joints, the nervous system and heart if it goes untreated. (Source: WBZ-TV - Breaking News, Weather and Spo...
Tuesday 6 June 2023
A Maine resident has died from the Powassan virus, a rare tick-borne illness, Maine’s Centers for Disease Control confirmed on Wednesday. The individual, who was likely infected in the state, developed neurologic symptoms and died while in the hospital, according to Maine’s CDC. This is the state’s first case of Powassan virus this year. In 2022, two individuals died from the illness, making this the third recorded Powassan death in Maine since 2015. Read More: Ticks Carry More Diseases Than Just Lyme. Here’s What You Need to Know [time-brightcove not-tgx=”true”] Like Lyme disease, which the CDC says impacts over 400,000 Americans each year, the disease is caused by a virus transmitted through ticks. Many people who contract the Powassan virus do not e...
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Tuesday 6 June 2023
PET scans for the first time show brain activity that could potentially explai...Read more on AuntMinnie.comRelated Reading: PET scans reveal brain activity related to menopause PET brain scans find links to PTSD severity in 9/11 responders PET tracers reveal long-term consequences of brain injuries Carbon-11 PET detects brain inflammation after Lyme disease PET imaging shows that depression alters the brain (Source: AuntMinnie.com Headlines)
Tuesday 6 June 2023
(MedPage Today) -- While tickborne diseases have been on the rise across the U.S., outdoor enthusiasts can take comfort knowing that most common infections aren't transmitted quickly, researchers said. For instance, Borrelia burgdorferi, the bacteria... (Source: MedPage Today Public Health)
Tuesday 6 June 2023
(MedPage Today) -- While tickborne diseases have been on the rise across the U.S., outdoor enthusiasts can take comfort knowing that most common infections aren't transmitted quickly, researchers said. For instance, Borrelia burgdorferi, the bacteria... (Source: MedPage Today Public Health)
Tuesday 6 June 2023
Lyme disease is a tickborne zoonosis for which serologic testing is the principal means of laboratory diagnosis. (Source: CDC Morbidity and Mortality Weekly Report)
Tuesday 6 June 2023
Why some people recover from Lyme disease, while others experience months, years or even decades of chronic symptoms has long puzzled doctors. New research offers some clues to an immune system marker in the blood that is elevated among people with lingering Lyme disease symptoms, even after…#lyme #interferon #klemenstrle #tuftsuniversity #strle #cdc #borrelia #robertadebiasi #ptlds #rebeccagreenberg (Source: Reuters: Health)
Tuesday 6 June 2023
Lyme disease is a bacterial infection caused by the bite of an infected black-legged tick, commonly known as a deer tick. Preventing tick bites is the best defense against the disease. And now there is good news for those looking for an alternative insect repellant to fight off ticks, says Dr. Omar Abu Saleh, a Mayo Clinic [...] (Source: News from Mayo Clinic)
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Tuesday 6 June 2023
(TellMed Strategies) Bay Area Lyme Foundation, a leading sponsor of Lyme disease research in the U.S., today announced the publication of new data finding that five herbal medicines had potent activity compared to commonly-used antibiotics in test tubes against Babesia duncani, a malaria-like parasite found on the West Coast of the U.S. that causes the disease babesiosis. (Source: EurekAlert! - Infectious and Emerging Diseases)
Tuesday 6 June 2023
WEDNESDAY, June 17, 2020 -- Tick monitoring and control is lacking in much of the United States despite a steady increase in tick-borne illnesses, such as Lyme disease, a new study finds. In the United States, tick-borne illnesses more than doubled... (Source: Drugs.com - Daily MedNews)
Tuesday 6 June 2023
EXCLUSIVE: Kelly Brooks, 27, of Hampshire, suffers from chronic Lyme disease - a tick-borne condition that has severe symptoms including agonising joint pain, fatigue and headaches. (Source: the Mail online | Health)
Tuesday 6 June 2023
Steven Williams was left bedridden and shaking for 18 hours a day after contracting the illness. (Source: BBC News | Health | UK Edition)
Tuesday 6 June 2023
(Bloomberg) — There are four critical facets of pandemic prevention, according to Lee Hannah, senior scientist at Conservation International. Three of them make immediate sense against the backdrop of our current emergency: stockpile masks and respirators; have testing infrastructure ready; and ban the global wildlife trade, including the open animal markets where COVID-19 may have first infected people. His fourth recommendation is more grandiose: “Take care of nature.” The assault on ecosystems that allowed COVID-19 to jump from animals to humans went far beyond merchants hunting and selling rare wildlife. Biodiversity—that is, the health of the entire ecosystem—can restrain pathogens before they ever leave the wild. “We need to tell people right now t...
Tuesday 6 June 2023
Mainstream medicine has failed many Lyme disease patients. It's fast becoming irrelevant. (Source: Forbes.com Healthcare News)
Tuesday 6 June 2023
The recent discovery of Lyme-infected ticks at the location of an outdoor wilderness program in North Carolina highlights the importance of vectorborne disease prevention. (Source: CDC Morbidity and Mortality Weekly Report)
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